2020
D. Bandelli, I. Muljajew, K. Scheuer, J. B. Max, C. Weber, F. H. Schacher, K. D. Jandt, U. S. SchubertCopolymerization of caprolactone isomers to obtain nanoparticles with constant hydrophobicity and tunable crystallinity Macromolecules 2020 , DOI: 10.1021/acs.macromol.0c00486.
B. Böttcher, B. Hoffmann, E. Garbe, T. Weise, Z. Cseresnyés, P. Brandt, S. Dietrich, D. Driesch, M. T. Figge, S. VylkovaThe transcription factor Stp2 is important for Candida albicans biofilm establishment and sustainability Front. Microbiol. 2020 , 11 , 794.
G. Cinar, C. Englert, M. Lehmann, I. NischangIn situ, quantitative assessment of multifunctional nanoscale drug delivery systems in human serum Anal. Chem. 2020 , 92 , 7932-7939.
Z. Cseresnyes, M. I. A. Hassan, H.-M. Dahse, K. Voigt, M. T. FiggeQuantitative impact of cell membrane fluorescence labeling on phagocytosis measurements in confrontation assays Front. Microbiol. 2020 , DOI: 10.3389/fmicb.2020.01193.
M. A. De Jesús-Téllez, D. M. Sánchez-Cerrillo, P. Quintana-Owen, U. S. Schubert, D. Contreras-López, C. Guerrero-SánchezKinetic investigations of quaternization reactions of poly[2-(dimethylamino)ethyl methacrylate] with diverse alkyl halides Macromol. Chem. Phys. 2020 , 221 , 1900543.
A. Medyukhina, M. Blickensdorf, Z. Cseresnyés, N. Ruef, J. V. Stein, M. T. Figge
P. Wei, G. Gangapurwala, D. Pretzel, L. Wang, S. Schubert, J. C. Brendel, U. S. SchubertTunable nanogels by host–guest interaction with carboxylate pillar[5]arene for controlled encapsulation and release of doxorubicin Nanoscale 2020 , 12 , 13595-13605.
A. Barbotin, I. Urbančič, S. Galiani, C. Eggeling, M. Booth, E. Sezginz-STED imaging and spectroscopy to investigate nanoscale membrane structure and dynamics Biophys. J. 2020 , 118 , 2448-2457.
A. A. Womiloju, C. Höppener, U. S. Schubert, S. HoeppenerMicrowave-assisted synthesis of core–shell nanoparticles - Insights into the growth of different geometries Part. Part. Syst. Charact. 2020 , 2000019.
T. A. Stanly, M. Fritzsche, S. Banerji, D. Shrestha, F. Schneider, C. Eggeling, D. G. JacksonThe cortical actin network regulates avidity-dependent binding of hyaluronan by the Lymphatic Vessel Endothelial receptor LYVE-1 J. Biol. Chem. 2020 , DOI: 10.1074/jbc.RA1119.011992.
B. Shkodra-Pula, A. Vollrath, U. S. Schubert, S. SchubertPolymer-based nanoparticles for biomedical applications in Frontiers of Nanoscience , Vol. 16 (Eds.: W. J. Parak, N. Feliu), Elsevier, 2020 , pp. 233-252.
B. Shkodra-Pula, C. Kretzer, P. Jordan, P. Klemm, A. Koeberle, D. Pretzel, E. Banoglu, S. Lorkowski, M. Wallert, S. Hoeppener, S. Stumpf, A. Vollrath, S. Schubert, O. Werz, U. S. SchubertEncapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity J. Nanobiotechnol. 2020 , DOI: 10.21203/rs.21203.rs-15745/v21201.
E. Sezgin, D. Carugo, I. Levental, E. Stride, C. EggelingCreating supported plasma membrane bilayers using acoustic pressure bioRxiv 2020 , DOI: 10.1101/2020.1101.1120.912840.
F. Schneider, P. Hernandez-Varas, C. Lagerholm, D. Shrestha, E. Sezgin, J. Roberti, G. Ossato, F. Hecht, C. Eggeling, I. UrbančičHigh photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopy J. Phys. D: Appl. Phys. 2020 , 53 , 64003.
F. Richter, L. Martin, K. Leer, E. Moek, F. Hausig, J. C. Brendel, A. TraegerTuning of endosomal escape and gene expression by functional groups, molecular weight and transfection medium: a structure–activity relationship study J. Mater. Chem. B 2020 , DOI: 10.1039/d1030tb00340a.
T. Hanke, S.-Y. Cheung, W. Kilu, J. Heering, X. Ni, V. Planz, S. Schierle, G. Faudone, M. Friedrich, M. Wanior, O. Werz, M. Windbergs, E. Proschak, M. Schubert-Zsilavecz, A. Chaikuad, S. Knapp, D. MerkA selective modulator of peroxisome proliferator-activated receptor γ with an unprecedented binding mode J. Med. Chem. 2020 , Doi: 10.1021/acs.jmedchem.1029b01786.
M. Dirauf, C. Grune, C. Weber, U. S. Schubert, D. FischerPoly(ethylene glycol) or poly(2-ethyl-2-oxazoline) – A systematic comparison of PLGA nanoparticles from the bottom up Eur. Polym. J. 2020 , 134 , 109801.
M. Dirauf, A. Erlebach, C. Weber, S. Hoeppener, J. R. Buchheim, M. Sierka, U. S. SchubertBlock copolymers composed of PEtOx and polyesteramides based on glycolic acid, L-valine, and L-isoleucine Macromolecules 2020 , DOI: 10.1021/acs.macromol.1020c00282.
M. G. Chini, A. Giordano, M. Potenza, S. Terracciano, K. Fischer, M. C. Vaccaro, E. Colarusso, I. Bruno, R. Riccio, A. Koeberle, O. Werz, G. BifulcoTargeting mPGES-1 by a combinatorial approach: Identification of the aminobenzothiazole scaffold to suppress PGE2 levels ACS Med. Chem. Lett. 2020 , DOI: 10.1021/acsmedchemlett.1029b00618.
P. Carravilla, J. L. Nieva, C. EggelingFluorescence microscopy of the HIV-1 envelope Viruses 2020 , 12 , 348.
A. Barbotin, I. Urbančič, S. Galiani, C. Eggeling, M. BoothBackground reduction in STED-FCS using coherent-hybrid STED bioRxiv 2020 , DOI: 10.1101/2020.1101.1106.895243.
J. Alex, K. González, T. Kindel, P. Bellstedt, C. Weber, T. Heinekamp, T. Orasch, C. Guerrero-Sanchez, U. S. Schubert, A. A. BrakhageCaspofungin functionalized polymethacrylates with antifungal properties Biomacromolecules 2020 , DOI: 10.1021/acs.biomac.0c00096.
H. Lindemann, M. Kühne, C. Grune, P. Warncke, S. Hofmann, A. Koschella, M. Godmann, D. Fischer, T. Heinzel, T. HeinzePolysaccharide nanoparticles bearing HDAC inhibitor as nontoxic nanocarrier for drug delivery Macromol. Biosci. 2020 , 2000039.
M. Grube, I. Perevyazko, T. Heinze, U. S. Schubert, I. Nischang,Revisiting very disperse macromolecule populations in hydrodynamic and light scattering studies of sodium carboxymethyl celluloses Carbohydr. Polym. 2020 , 229 , 115452.
S. C. Koeberle, A. Gollowitzer, J. Laoukili, O. Kranenburg, O. Werz, A. Koeberle, A. P. KippDistinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms Redox Biology 2020 , 28 , 101388.
I. Muljajew, A. Erlebach, C. Weber, J. R. Buchheim, M. Sierka, U. S. SchubertA polyesteramide library from dicarboxylic acids and 2,2′-bis(2-oxazoline): synthesis, characterization, nanoparticle formulation and molecular dynamics simulations Polym. Chem. 2020 , 11 , 112-124.
M. Werner, S. Pace, A. Czapka, P. M. Jordan, J. Gerstmeier, A. Koeberle, O. WerzCommunication between human macrophages and epithelial cancer cell lines dictates lipid mediator biosynthesis Cell. Mol. Life Sci. 2020 , DOI: 10.1007/s00018-00019-03413-w.
T. Wloka, S. Czich, M. Kleinsteuber, E. Moek, C. Weber, M. Gottschaldt, K. Liefeith, U. S. SchubertMicrofabrication of 3D-hydrogels via two-photon polymerization of poly(2-ethyl-2-oxazoline) diacrylates Eur. Polym. J. 2020 , 122 , 109295.
A. M. Ali, T. Deckert-Gaudig, M. Egiza, V. Deckert, T. YoshitakeNear- and far-field Raman spectroscopic studies of nanodiamond composite films deposited by coaxial arc plasma Appl. Phys. Lett. 2020 , 116 , 041601.
C. Chen, F. Richter, C. Guerrero-Sanchez, A. Traeger, U. S. Schubert, A. Feng, S. H. ThangCell-penetrating, peptide-based RAFT agent for constructing penetration enhancers ACS Macro Letters 2020 , 9 , 260-265.
C. Cokca, L. Zartner, I. Tabujew, D. Fischer, K. PenevaIncorporation of indole significantly improves the transfection efficiency of guanidinium-containing poly(methacrylamide)s Macromol. Rapid Commun. 2020 , 41 , 2070012.
J. A. Czaplewska, G. Gangapurwala, A. Vollrath, M. Pröhl, T. Majdanski, D. Pretzel, S. Hoeppener, U. S. Schubert, M. GottschaldtSynthesis of a fructose decorated PAGE-b-PEG-b-PLGA polymer with subsequent formulation of nanoparticles Colloids Surf. A Physicochem. Eng. Asp. 2020 , 124701.
S. Deinhardt-Emmer, K. Rennert, E. Schicke, Z. Cseresnyés, M. Windolph, S. Nietzsche, R. Heller, F. Siwczak, K. F. Haupt, S. Carlstedt, M. Schacke, M. T. Figge, C. Ehrhardt, B. Löffler, A. S. MosigCo-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model Biofabrication 2020 , 12 , 025012.
A. Erlebach, I. Muljajew, M. Chi, C. Bückmann, C. Weber, U. S. Schubert, M. SierkaPredicting solubility of small molecules in macromolecular compounds for nanomedicine application from atomistic simulations Adv. Theory Simul. 2020 , DOI: 10.1002/adts.202000001.
E. Gardey, F. H. Sobotta, S. Hoeppener, T. Bruns, A. Stallmach, J. C. BrendelInfluence of core cross-linking and shell composition of polymeric micelles on immune response and their interaction with human monocytes Biomacromolecules 2020 , DOI: 10.1021/acs.biomac.9b01656.
M. Gericke, P. Schulze, T. HeinzeNanoparticles based on hydrophobic polysaccharide derivatives—formation principles, characterization techniques, and biomedical applications Macromol. Biosci. 2020 , 1900415.
M. Grube, G. Cinar, U. S. Schubert, I. NischangIncentives of using the hydrodynamic invariant and sedimentation parameter for the study of naturally- and synthetically-based macromolecules in solution Polymers 2020 , 12 , 277.
K. Hiesinger, A. Schott, J. S. Kramer, R. Blöcher, F. Witt, S. K. Wittmann, D. Steinhilber, D. Pogoryelov, J. Gerstmeier, O. Werz, E. ProschakDesign of dual inhibitors of soluble epoxide hydrolase and LTA4 hydrolase ACS Med. Chem. Lett. 2020 , 11 , 298-302.
C. Höppener, F. H. Schacher, V. DeckertMultimodal characterization of resin embedded and sliced polymer nanoparticles by means of tip-enhanced raman spectroscopy and force–distance curve based atomic force microscopy Small 2020 , 1907418.
J. Hübner, T. Deckert-Gaudig, J. Glorian, V. K. Deckert, D. SpitzerSurface characterization of nanoscale co-crystals enabled through tip enhanced raman spectroscopy Nanoscale 2020 , DOI: 10.1039/D1030NR00397B.
S. M. A. S. Keshk, A. A. El-Zahhar, Q. A. Alsulami, M. Jaremko, S. Bondock, T. HeinzeSynthesis, characterization and ampyrone drug release behavior of magnetite nanoparticle/2,3-dialdehyde cellulose-6-phosphate composite Cellulose 2020 , 27 , 1603-1618.
A. Koschella, C.-Y. Chien, T. Iwata, M. S. Thonhofer, T. M. Wrodnigg, T. HeinzeAll sugar based cellulose derivatives synthesized by azide–alkyne click chemistry Macromol. Chem. Phys. 2020 , 221 , 1900343.
G. Lauro, S. Terracciano, V. Cantone, D. Ruggiero, K. Fischer, S. Pace, O. Werz, I. Bruno, G. BifulcoA combinatorial virtual screening approach driving the synthesis of 2,4-thiazolidinedione-based molecules as new dual mPGES-1/5-LO inhibitors ChemMedChem 2020 , 15 , 481-489.
V. D. Lechuga-Islas, G. Festag, M. Rosales-Guzmán, O. E. Vega-Becerra, R. Guerrero-Santos, U. S. Schubert, C. Guerrero-SánchezQuasi-block copolymer design of quaternized derivatives of poly(2-(dimethylamino)ethyl methacrylate): Investigations on thermo-induced self-assembly Eur. Polym. J. 2020 , 124 , 109457.
E. Matuszyk, E. Sierka, M. Rodewald, H. Bae, T. Meyer, E. Kus, S. Chlopicki, M. Schmitt, J. Popp, M. BaranskaDifferential response of liver sinusoidal endothelial cells and hepatocytes to oleic and palmitic acid revealed by Raman and CARS imaging Biochim. Biophys. Acta Mol. Basis Disease 2020 , 1866 , 165763.
J. B. Max, P. J. Mons, J. C. Tom, F. H. SchacherDouble hydrophilic poly(ethylene oxide)-block-poly(dehydroalanine) block copolymers: Comparison of two different synthetic routes Macromol. Chem. Phys. 2020 , 221 , 1900383.
A. Olgac, A. Carotti, C. Kretzer, S. Zergiebel, A. Seeling, U. Garscha, O. Werz, A. Macchiarulo, E. BanogluDiscovery of novel 5-lipoxygenase-activating protein (FLAP) inhibitors by exploiting a multistep virtual screening protocol J. Chem. Inf. Model. 2020 , 60 , 1737-1748.
Z. Rao, P. M. Jordan, Y. Wang, D. Menche, S. Pace, J. Gerstmeier, O. WerzDifferential role of vacuolar (H+)-ATPase in the expression and activity of cyclooxygenase-2 in human monocytes Biochem. Pharmacol. 2020 , 175 , 113858.
V. V. Shumyantseva, T. V. Bulko, A. V. Kuzikov, R. A. Masamrekh, A. Y. Konyakhina, I. Romanenko, J. B. Max, M. Köhler, A. A. Gilep, S. A. Usanov, D. V. Pergushov, F. H. Schacher, L. V. SigolaevaAll-electrochemical nanocomposite two-electrode setup for quantification of drugs and study of their electrocatalytical conversion by cytochromes P450 Electrochimica Acta 2020 , 336 , 135579.
P. Singh, T. Deckert-Gaudig, Z. Zhang, V. DeckertPlasmon induced deprotonation of 2-mercaptopyridine Analyst 2020 , 145 , 2106-2110.
M. Sittig, B. Schmidt, H. Görls, T. Bocklitz, M. Wächtler, S. Zechel, M. D. Hager, B. DietzekFluorescence upconversion by triplet-triplet annihilation in all-organic poly(methacrylate)-terpolymers Phys. Chem. Chem. Phys. 2020 , 22 , 4072-4079.
R. Takahashi, S. Miwa, F. H. Sobotta, J. H. Lee, S. Fujii, N. Ohta, J. C. Brendel, K. SakuraiUnraveling the kinetics of the structural development during polymerization-induced self-assembly: decoupling the polymerization and the micelle structure Polym. Chem. 2020 , 11 , 1514-1524.
A. Traeger, S. Voelker, B. Shkodra-Pula, C. Kretzer, S. Schubert, M. Gottschaldt, U. S. Schubert, O. WerzImproved bioactivity of the natural product 5-lipoxygenase inhibitor hyperforin by encapsulation into polymeric nanoparticles Mol. Pharm. 2020 , 17 , 810-816.
P. Wei, J. A. Czaplewska, L. Wang, S. Schubert, J. C. Brendel, U. S. SchubertStraightforward access to glycosylated, acid sensitive nanogels by host–guest interactions with sugar-modified pillar[5]arenes ACS Macro Letters 2020 , 9 , 540-545.
P. Wei, F. H. Sobotta, C. Kellner, D. Bandelli, S. Hoeppener, S. Schubert, J. C. Brendel, U. S. SchubertDegradable polycaprolactone nanoparticles stabilized via supramolecular host–guest interactions with pH-responsive polymer-pillar[5]arene conjugates Polym. Chem. 2020 , 11 , 1985-1997.
F. Wendler, J. C. Tom, M. Sittig, P. Biehl, B. Dietzek, F. H. SchacherBlock copolymers featuring highly photostable photoacids based on vinylnaphthol: Synthesis and self-assembly Macromol. Rapid Commun. 2020 , 41 , 1900607.
2019
F. Wendler, J. C. Tom, F. H. SchacherSynthesis and self-assembly of photoacid-containing block copolymers based on 1-naphthol Polym. Chem. 2019 , 10 , 5602-5616.
D. Bandelli, J. Alex, C. Weber, U. S. SchubertPolyester stereocomplexes beyond PLA: Could synthetic opportunities revolutionize established material blending? Macromol. Rapid Commun. 2019 , 1900560.
T. Chakraborty, M. K. Driscoll, E. Jeffery, M. M. Murphy, P. Roudot, B.-J. Chang, S. Vora, W. M. Wong, C. D. Nielson, H. Zhang, V. Zhemkov, C. Hiremath, E. D. De La Cruz, Y. Yi, I. Bezprozvanny, H. Zhao, R. Tomer, R. Heintzmann, J. P. Meeks, D. K. Marciano, S. J. Morrison, G. Danuser, K. M. Dean, R. FiolkaLight-sheet microscopy of cleared tissues with isotropic, subcellular resolution Nat. Meth. 2019 , 16 , 1109-1113.
C. Favard, J. Chojnacki, P. Merida, N. Yandrapalli, J. Mak, C. Eggeling, D. MuriauxHIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly Sci. Adv. 2019 , 5 , eaaw8651.
E. Romp, V. Arakandy, J. Fischer, C. Wolz, A. Siegmund, B. Löffler, L. Tuchscherr, O. Werz, U. GarschaExotoxins from Staphylococcus aureus activate 5-lipoxygenase and induce leukotriene biosynthesis Cell. Mol. Life Sci. 2019 , DOI: 10.1007/s00018-00019-03393-x.
M. Rosales-Guzmán, O. Pérez-Camacho, C. Guerrero-Sánchez, S. Harrisson, R. Torres-Lubián, J. Vitz, U. S. Schubert, E. Saldívar-GuerraSemiautomated parallel RAFT copolymerization of isoprene with glycidyl methacrylate ACS Comb. Sci. 2019 , 21 , 771-781.
F. Wendler, M. Sittig, J. C. Tom, B. Dietzek, F. H. SchacherPolymeric photoacids based on naphthols - Design criteria, photostability, and light-mediated release Chem. Eur. J. 2019 , DOI: 10.1002/chem.201903819.
R. Meyer, S. Trautmann, K. Rezaei, A. George, A. Turchanin, V. DeckertSynergy of photoinduced force microscopy and tip-enhanced Raman spectroscopy—A correlative study on MoS2 ACS Photonics 2019 , 6 , 1191-1198.
J. B. Max, D. V. Pergushov, L. V. Sigolaeva, F. H. SchacherPolyampholytic graft copolymers based on polydehydroalanine (PDha) – synthesis, solution behavior and application as dispersants for carbon nanotubes Polym. Chem. 2019 , 10 , 3006-3019.
J. Langer, D. Jimenez de Aberasturi, J. Aizpurua, R. A. Alvarez-Puebla, B. Auguié, J. J. Baumberg, G. C. Bazan, S. E. J. Bell, A. Boisen, A. G. Brolo, J. Choo, D. Cialla-May, V. Deckert, L. Fabris, K. Faulds, F. J. García de Abajo, R. Goodacre, D. Graham, A. J. Haes, C. L. Haynes, C. Huck, T. Itoh, M. Käll, J. Kneipp, N. A. Kotov, H. Kuang, E. C. Le Ru, H. K. Lee, J.-F. Li, X. Y. Ling, S. Maier, T. Mayerhoefer, M. Moskovits, K. Murakoshi, J.-M. Nam, S. Nie, Y. Ozaki, I. Pastoriza-Santos, J. Perez-Juste, J. Popp, A. Pucci, S. Reich, B. Ren, G. C. Schatz, T. Shegai, S. Schlücker, T. Li-Lin, K. G. Thomas, Z.-Q. Tian, R. P. Van Duyne, T. Vo-Dinh, Y. Wang, K. A. Willets, C. Xu, H. Xu, Y. Xu, Y. S. Yamamoto, B. Zhao, L. M. Liz-MarzánPresent and future of surface enhanced Raman scattering ACS Nano 2019 , DOI: 10.1021/acsnano.1029b04224.
J. Ernst, M. Klinger-Strobel, J. Thamm, O. Makarewicz, M. Pletz, D. FischerPharmazeutische Industrie 2019 , 81 , 248-255.
J. K. Elter, P. Biehl, M. Gottschaldt, F. H. SchacherCore-crosslinked worm-like micelles from polyether-based diblock terpolymers Polym. Chem. 2019 , DOI: 10.1039/C1039PY01054H.
V. H. Bac, B. S. Paulsen, L. V. Truong, A. Koschella, T. C. Trinh, C. W. Wold, S. Yogarajah, T. HeinzeNeutral polysaccharide from the leaves of pseuderanthemum carruthersii: Presence of 3-O-methyl galactose and anti-inflammatory activity in LPS-stimulated RAW 264.7 cells Polymers 2019 , 11 , 1219.
L. Applová, J. Karlíčková, P. Warncke, K. Macáková, M. Hrubša, M. Macháček, V. Tvrdý, D. Fischer, P. Mladěnka4-Methylcatechol, a flavonoid metabolite with potent antiplatelet effects Mol. Nutr. Food Res. 2019 , 63 , 1900261.
I. Perevyazko, A. Lezov, A. S. Gubarev, E. Lebedeva, G. Festag, C. Guerrero-Sanchez, N. Tsvetkov, U. S. SchubertStructure-property relationships via complementary hydrodynamic approaches: Poly(2-(dimethylamino)ethyl methacrylate)s Polymer 2019 , 182 , 121828.
L. V. Sigolaeva, T. V. Bulko, M. S. Kozin, W. Zhang, M. Köhler, I. Romanenko, J. Yuan, F. H. Schacher, D. V. Pergushov, V. V. ShumyantsevaLong-term stable poly(ionic liquid)/MWCNTs inks enable enhanced surface modification for electrooxidative detection and quantification of dsDNA Polymer 2019 , 168 , 95-103.
C. St Thomas, C. N. Muñoz López, E. J. Jiménez Regalado, M. A. de Jesús Tellez, G. Festag, U. S. Schubert, C. Guerrero-SánchezPreparation of hydrophobically modified associating multiblock copolymers via a one-pot aqueous RAFT polymerization Polym. Chem. 2019 , DOI: 10.1039/C1039PY01311C.
M. Wang, J. Zhang, C. Guerrero-Sanchez, U. S. Schubert, A. Feng, S. H. ThangEnzyme degassing for oxygen-sensitive reactions in open vessels of an automated parallel synthesizer: RAFT polymerizations ACS Comb. Sci. 2019 , 21 , 643-649.
M. Wallert, M. Ziegler, X. Wang, A. Maluenda, X. Xu, M. L. Yap, R. Witt, C. Giles, S. Kluge, M. Hortmann, J. Zhang, P. Meikle, S. Lorkowski, K. Peterα-Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injury Redox Biology 2019 , 26 , 101292.
H. L. Cao, X. Y. Liu, K. D. JandtThe action-network of nanomaterials in "On the issue of transparency and reproducibility in nanomedicine" Nat. Nanotechn. 2019 , 14 , 629-635.
D. Bandelli, C. Weber, U. S. SchubertStrontium isopropoxide: A highly active catalyst for the ring-opening polymerization of lactide and various lactones Macromol. Rapid Commun. 2019 , 1900306.
Z. Rao, S. Pace, P. M. Jordan, R. Bilancia, F. Troisi, F. Börner, N. Andreas, T. Kamradt, D. Menche, A. Rossi, C. N. Serhan, J. Gerstmeier, O. WerzVacuolar (H+)-ATPase critically regulates specialized proresolving mediator pathways in human M2-like monocyte-derived macrophages and has a crucial role in resolution of inflammation J. Immunol. 2019 , 203 , 1031-1043.
H. Würfel, M. Kayser, T. HeinzeNon-aqueous solvent for efficient dissolution of polygalacturonic acid Carbohydr. Polym. 2019 , 207 , 791-795.
H. Würfel, M. Kayser, T. HeinzeTrimethylsilylation of Polygalacturonic Acid Macromol. Chem. Phys. 2019 , 220 , 1900002.
M. Kostag, M. Gericke, T. Heinze, O. A. El SeoudTwenty-five years of cellulose chemistry: innovations in the dissolution of the biopolymer and its transformation into esters and ethers Cellulose 2019 , 26 , 139-184.
C. Pinon-Balderrama, C. Leyva-Porras, R. Olayo-Valles, J. Revilla-Vazquez, U. S. Schubert, C. Guerrero-Sanchez, J. Bonilla-CruzSelf-assembly investigations of sulfonated poly(methyl methacrylate-block-styrene) diblock copolymer thin films Adv. Polym. Technol. 2019 , 2019 , 11.
A. Sierra-Fernandez, S. C. De la Rosa-García, R. Yañez-Macías, C. Guerrero-Sanchez, L. S. Gomez-Villalba, S. Gómez-Cornelio, M. E. Rabanal, U. S. Schubert, R. Fort, P. QuintanaSol–gel synthesis of Mg(OH)2 and Ca(OH)2 nanoparticles: a comparative study of their antifungal activity in partially quaternized p(DMAEMA) nanocomposite films J. Sol-Gel Sci. Technol. 2019 , 89 , 310-321.
M. Zink, K. Hotzel, U. S. Schubert, T. Heinze, D. FischerAmino Acid–Substituted Dextran-Based Non-Viral Vectors for Gene Delivery Macromol. Biosci. 2019 , 19 , 1900085.
J. Gerstmeier, C. Kretzer, S. Di Micco, L. Miek, H. Butschek, V. Cantone, R. Bilancia, R. Rizza, F. Troisi, N. Cardullo, C. Tringali, A. Ialenti, A. Rossi, G. Bifulco, O. Werz, S. PaceNovel benzoxanthene lignans that favorably modulate lipid mediator biosynthesis: A promising pharmacological strategy for anti-inflammatory therapy Biochem. Pharmacol. 2019 , 165 , 263-274.
J. Gerstmeier, J. Seegers, F. Witt, B. Waltenberger, V. Temml, J. M. Rollinger, H. Stuppner, A. Koeberle, D. Schuster, O. WerzGinkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis Frontiers in Pharmacology 2019 , 10.
S. Shekfeh, B. Çalışkan, K. Fischer, T. Yalçın, U. Garscha, O. Werz, E. BanogluA Multi‐step Virtual Screening Protocol for the Identification of Novel Non‐acidic Microsomal Prostaglandin E2 Synthase‐1 (mPGES‐1) Inhibitors ChemMedChem 2019 , 14 , 273-281.
M. Wallert, J. Bauer, S. Kluge, L. Schmölz, Y.-C. Chen, M. Ziegler, A. K. Searle, A. Maxones, M. Schubert, M. Thürmer, H. Pein, A. Koeberle, O. Werz, M. Birringer, K. Peter, S. LorkowskiThe vitamin E derivative garcinoic acid from Garcinia kola nut seeds attenuates the inflammatory response Redox Biology 2019 , 24 , 101166.
M. Reifarth, W. Müller, B. Shkodra-Pula, H. Görls, U. S. Schubert, R. Heintzmann, S. HoeppenerElectron density of polymeric nanoparticles determined by image processing of transmission electron micrographs: Insights into heavy metal staining processes Particle & Particle Systems Characterization 2019 , 1800324.
M. Sahn, C. Weber, U. S. SchubertPoly(2-oxazoline)-containing triblock copolymers: Synthesis and applications Polym. Rev. 2019 , doi: 10.1080/15583724.2018.1496930.
P. Wei, G. Gangapurwala, D. Pretzel, M. N. Leiske, L. Wang, S. Hoeppener, S. Schubert, J. C. Brendel, U. S. SchubertSmart pH-sensitive nanogels for controlled release in an acidic environment Biomacromolecules 2019 , 20 , 130-140.
M. Werner, P. M. Jordan, E. Romp, A. Czapka, Z. Rao, C. Kretzer, A. Koeberle, U. Garscha, S. Pace, H.-E. Claesson, C. N. Serhan, O. Werz, J. GerstmeierTargeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome The FASEB Journal 2019 , doi: 10.1096/fj.201802509R.
L. Wondraczek, G. Pohnert, F. H. Schacher, A. Köhler, M. Gottschaldt, U. S. Schubert, K. Küsel, A. A. BrakhageArtificial microbial arenas: Materials for observing and manipulating microbial consortia Adv. Mater. 2019 , 31 , 1900284.
B. Shkodra-Pula, C. Grune, A. Traeger, A. Vollrath, S. Schubert, D. Fischer, U. S. SchubertEffect of surfactant on the size and stability of PLGA nanoparticles encapsulating a protein kinase C inhibitor Int. J. Pharm. 2019 , 566 , 756-764.
C. Reichardt, S. Monro, F. H. Sobotta, K. L. Colón, T. Sainuddin, M. Stephenson, E. Sampson, J. Roque, H. Yin, J. C. Brendel, C. G. Cameron, S. McFarland, B. DietzekPredictive strength of photophysical measurements for in vitro photobiological activity in a series of Ru(II) polypyridyl complexes derived from π-extended ligands Inorg. Chem. 2019 , 58 , 3156-3166.
H. Qiu, Z. Yang, M. Köhler, J. Ling, F. H. SchacherSynthesis and solution self-assembly of poly(1,3-dioxolane) Macromolecules 2019 , 52 , 3359-3366.
N. Engel, M. Dirauf, S. Seupel, M. N. Leiske, S. Schubert, U. S. SchubertUtilization of 4-(trifluoromethyl)benzenesulfonates as counter ions tunes the initiator efficiency of sophisticated initiators for the preparation of well-defined poly(2-oxazoline)s Macromol. Rapid Commun. 2019 , 40 , 1900094.
N. Al Nakeeb, I. Nischang, B. V. K. J. SchmidtTannic acid-mediated aggregate stabilization of poly(N-vinylpyrrolidone)-b-poly(oligo (ethylene glycol) methyl ether methacrylate) double hydrophilic block copolymers Nanomaterials 2019 , 9 , 662.
M. Maurer, M. S. Gresnigt, A. Last, T. Wollny, F. Berlinghof, R. Pospich, Z. Cseresnyes, A. Medyukhina, K. Graf, M. Gröger, M. Raasch, F. Siwczak, S. Nietzsche, I. D. Jacobsen, M. T. Figge, B. Hube, O. Huber, A. S. MosigA three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies Biomaterials 2019 , 220 , 119396.
M. I. A. Hassan, Z. Cseresnyes, N. Al-Zaben, H.-M. Dahse, R. J. Vilela de Oliveira, G. Walther, K. Voigt, M. T. FiggeThe geographical region of origin determines the phagocytic vulnerability of Lichtheimia strains Environ. Microbiol. , DOI: 10.1111/1462-2920.14752.
D. Bandelli, J. Alex, C. Helbing, N. Ueberschaar, H. Görls, P. Bellstedt, C. Weber, K. D. Jandt, U. S. SchubertPoly(ethylglycolide): A well-defined polyester matching the hydrophilic hydrophobic balance of PLA Polym. Chem. 2019 , DOI: 10.1039/c1039py00875f.
I. Tabujew, C. Cokca, L. Zartner, U. S. Schubert, I. Nischang, D. Fischer, K. PenevaThe influence of gradient and statistical arrangements of guanidinium or primary amine groups in poly(methacrylate) copolymers on their DNA binding affinity Journal of Materials Chemistry B 2019, DOI: 10.1039/c9tb01269a.
A. Barbotin, S. Galiani, I. Urbančič, C. Eggeling, M. J. BoothAdaptive optics allows STED-FCS measurements in the cytoplasm of living cells Optics Express 2019 , 27 , 23378-23395.
T. Klein, F. V. Gruschwitz, S. Rogers, S. Hoeppener, I. Nischang, J. C. BrendelThe influence of directed hydrogen bonds on the self-assembly of amphiphilic polymers in water J. Colloid Interface Sci. 2019 , 557 , 488-497.
M. E. Mikhailova, A. S. Senchukova, A. A. Lezov, A. S. Gubarev, A.-K. Trützschler, U. S. Schubert, N. V. TsvetkovStabilization of Silver Nanoparticles by Cationic Aminoethyl Methacrylate Copolymers in Aqueous Media—Effects of Component Ratios and Molar Masses of Copolymers Polymers 2019 , 11 , 1647.
M. Raasch, E. Fritsche, A. Kurtz, M. Bauer, A. S. MosigMicrophysiological systems meet hiPSC technology - New tools for disease modeling of liver infections in basic research and drug development Adv. Drug Delivery Rev. 2019 , 140 , 51-67.
E. Rossegger, F. Pirolt, S. Hoeppener, U. S. Schubert, O. Glatter, F. WiesbrockCrosslinkable/functionalizable poly(2-oxazoline)based micelles Eur. Polym. J. 2019 , 121 , 109305.
I. Tabujew, M. Heidari, C. Freidel, M. Helm, L. Tebbe, U. Wolfrum, K. Nagel-Wolfrum, K. Koynov, P. Biehl, F. H. Schacher, R. Potestio, K. PenevaTackling the limitations of copolymeric small interfering RNA delivery agents by a combined experimental–computational approach Biomacromolecules 2019 , 20 , 4389-4406.
I. Tabujew, M. Willig, N. Leber, C. Freidel, I. Negwer, K. Koynov, M. Helm, K. Landfester, R. Zentel, K. Peneva, V. MailänderOvercoming the barrier of CD8+ T cells: Two types of nano-sized carriers for siRNA transport Acta Biomaterialia 2019 , 100 , 338-351.
R. Yañez-Macías, A. Muñoz-Bonilla, M. A. De Jesús-Tellez, H. Maldonado-Textle, C. Guerrero-Sánchez, U. S. Schubert, R. Guerrero-SantosCombinations of antimicrobial polymers with nanomaterials and bioactives to improve biocidal therapies Polymers 2019 , 11 , 1789.
M. Yarbakht, P. Pradhan, N. Köse-Vogel, H. Bae, S. Stengel, T. Meyer, M. Schmitt, A. Stallmach, J. Popp, T. W. Bocklitz, T. BrunsNonlinear multimodal imaging characteristics of early septic liver injury in a mouse model of peritonitis Anal. Chem. 2019 , 91 , 11116-11121.
2018
C. Englert, J. C. Brendel, T. C. Majdanski, T. Yildirim, S. Schubert, M. Gottschaldt, N. Windhab, U. S. Schubert, Pharmapolymers in the 21st Century: Synthetic Polymers in Drug Delivery Applications ", Prog. Polym. Sci. 2018 , DOI: 10.1016/j.progpolymsci.2018.1007.1005.
P. Dasari, I. A. Shopova, M. Stroe, D. Wartenberg, H. Martin-Dahse, N. Beyersdorf, P. Hortschansky, S. Dietrich, Z. Cseresnyés, M. T. Figge, M. Westermann, C. Skerka, A. A. Brakhage, P. F. Zipfel, Aspf2 from Aspergillus fumigatus recruits human immune regulators for immune evasion and cell damage ", Front. Immunol. 2018 , 9 , 1635.
L. Vieider, E. Romp, V. Temml, J. Fischer, C. Kretzer, M. Schoenthaler, A. Taha, V. Hernández-Olmos, S. Sturm, D. Schuster, O. Werz, U. Garscha, B. Matuszczak, Synthesis, biological evaluation and structureactivity relationships of diflapolin analogues as dual sEH/FLAP inhibitors ", ACS Med. Chem. Lett. 2018 , DOI: 10.1021/acsmedchemlett.8b00415.
M. Brunzel, T. Majdanski, J. Vitz, I. Nischang, U. Schubert, Fast screening of diol impurities in methoxy poly(ethylene glycol)s (mPEG)s by liquid chromatography on monolithic silica rods ", Polymers 2018 , 10 , 1395.
T. C. Majdanski, J. Vitz, A. Meier, M. Brunzel, S. Schubert, I. Nischang, U. S. Schubert, Green ethers as solvent alternatives for anionic ring-opening polymerizations of ethylene oxide (EO): In-situ kinetic and advanced characterization studies ", Polymer 2018 , 159 , 86-94.
M. Dirauf, D. Bandelli, C. Weber, H. Görls, M. Gottschaldt, U. S. Schubert, TBD-catalyzed ring-opening polymerization of alkyl-substituted morpholine-2,5-dione derivatives ", Macromol. Rapid Commun. 2018 , 39 , 1800433.
H. Pein, A. Ville, S. Pace, V. Temml, U. Garscha, M. Raasch, K. Alsabil, G. Viault, C.-P. Dinh, D. Guilet, F. Troisi, K. Neukirch, S. König, R. Bilancia, B. Waltenberger, H. Stuppner, M. Wallert, S. Lorkowski, C. Weinigel, S. Rummler, M. Birringer, F. Roviezzo, L. Sautebin, J.-J. Helesbeux, D. Séraphin, A. Mosig, D. Schuster, A. Rossi, P. Richomme, O. Werz, A. Koeberle, Endogenous metabolites of vitamin E limit inflammation by targeting 5 lipoxygenase ", Nat. Commun. 2018 , 9 , 3834.
H. Würfel, M. Kayser, T. Heinze, Efficient and catalyst-free synthesis of cellulose acetoacetates ", Cellulose 2018 , 25 , 4919-4928.
K. Ganske, T. Heinze, Evaluation of the synthesis of soluble aromatic cellulose carbonates of low degree of substitution ",Macromol. Chem. Phys. 2018 , 219 , 1800152.
T. Bus, A. Traeger, U. S. Schubert, The great escape: how cationic polyplexes overcome the endosomal barrier ", J. Mater. Chem. B 2018 , 6 , 6904-6918.
M. Bauer, L. Tauhardt, H. M. L. Lambermont-Thijs, K. Kempe, R. Hoogenboom, U. S. Schubert, D. Fischer, Rethinking the impact of the protonable amine density on cationic polymers for gene delivery: A comparative study of partially hydrolyzed poly(2-ethyl-2-oxazoline)s and linear poly(ethylene imine)s ", 2018 , 133 , 112-121.
J. F. Herrmann, C. Höppener, Dumbbell gold nanoparticle dimer antennas with advanced optical properties ", Beilst. J. Nanotechnol. 2018 , 9 , 2188-2197.
R. Meyer, X. Yao, V. Deckert, Latest instrumental developments and bioanalytical applications in tip-enhanced Raman spectroscopy ", Trends Anal. Chem. 2018 , 102 , 250-258.
D. Bandelli, C. Helbing, C. Weber, M. Seifert, I. Muljajew, K. D. Jandt, U. S. Schubert, Maintaining the hydrophilichydrophobic balance of polyesters with adjustable crystallinity for tailor-made nanoparticles ", Macromolecules 2018 , 51 , 5567-5576.
S.-Y. Cheung, M. Werner, L. Esposito, F. Troisi, V. Cantone, S. Liening, S. König, J. Gerstmeier, A. Koeberle, R. Bilancia, R. Rizza, A. Rossi, F. Roviezzo, V. Temml, D. Schuster, H. Stuppner, M. Schubert-Zsilavecz, O. Werz, T. Hanke, S. Pace, Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation ", Eur. J. Med. Chem. 2018 , 156 , 815-830.
A. Koeberle, A. Henkel, M. Verhoff, L. Tausch, S. König, D. Fischer, N. Kather, S. Seitz, M. Paul, J. Jauch, O. Werz, Triterpene acids from Frankincense and semi-synthetic derivatives that inhibit 5-lipoxygenase and cathepsin G ", Molecules 2018 , 23 , 506.
A.-K. Trützschler, T. Bus, M. Sahn, A. Traeger, C. Weber, U. S. Schubert, The power of shielding: Low toxicity and high transfection performance of cationic graft copolymers containing poly(2-oxazoline) side chains ", Biomacromolecules 2018 , 19 , 2759-2771.
M. Grube, M. N. Leiske, U. S. Schubert, I. Nischang, POx as an alternative to PEG? A hydrodynamic and light scattering study ", Macromolecules 2018 , 51 , 1905-1916.
Z. T. Gür, B. Çalışkan, U. Garscha, A. Olgaç, U. S. Schubert, J. Gerstmeier, O. Werz, E. Banoglu, Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7 ", Eur. J. Med. Chem. 2018 , 150 , 876-899.
D. Hertz, M. N. Leiske, T. Wloka, A. Traeger, M. Hartlieb, M. M. Kessels, S. Schubert, B. Qualmann, U. S. Schubert, Comparison of random and gradient amino functionalized poly(2-oxazoline)s: Can the transfection efficiency be tuned by the macromolecular structure? ", J. Polym. Sci., Part A: Polym. Chem. 2018 , DOI: 10.1002/pola.29000.
M. N. Leiske, F. H. Sobotta, F. Richter, S. Hoeppener, J. C. Brendel, A. Traeger, U. S. Schubert, How to tune the gene delivery and biocompatibility of poly(2-(4-aminobutyl)-2-oxazoline) by self- and coassembly ", Biomacromolecules 2018 , 19 , 748-760.
I. Muljajew, C. Weber, I. Nischang, U. Schubert, PMMA-g-OEtOx graft copolymers: Influence of grafting degree and side chain length on the conformation in aqueous solution ", Materials 2018 , 11 , 528.
M. Reifarth, S. Hoeppener, U. S. Schubert, Uptake and intracellular fate of engineered nanoparticles in mammalian cells: Capabilities and limitations of transmission electron microscopypolymerbased nanoparticles ", Adv. Mater. 2018 , 30 , 1703704.
W. S. Zhang, X. Q. Yu, Y. Li, Z. Q. Su, K. D. Jandt, G. Wei, Protein-mimetic peptide nanofibers: Motif design, self-assembly synthesis, and sequence-specific biomedical applications ", Prog. Polym. Sci. 2018 , 80 , 94-124.
M. Reifarth, U. S. Schubert, S. Hoeppener, Considerations for the uptake characteristic of inorgainc nanoparticles into mammalian cells - Insights gained by TEM investigations ", Adv. Biosys. 2018 , DOI: 10.1002/adbi.201700254.
M. Sahn, L. M. Stafast, M. Dirauf, D. Bandelli, C. Weber, U. S. Schubert, LCST behavior of poly(2-ethyl-2-oxazoline) containing diblock and triblock copolymers ", Eur. Polym. J. 2018 , 100 , 57-66.
F. H. Sobotta, F. Hausig, D. O. Harz, S. Hoeppener, U. S. Schubert, J. C. Brendel, Oxidation-responsive micelles by a one-pot polymerization-induced self-assembly approach ", Polym. Chem. 2018 , 9 , 1593-1602.
P. Wei, S. Götz, S. Schubert, J. C. Brendel, U. S. Schubert, Accelerating the acidic degradation of a novel thermoresponsive polymer by host-guest interaction ", 2018 , 9 , 2634-2642.
A.-K. Trützschler, T. Bus, M. Reifarth, J. C. Brendel, S. Hoeppener, A. Traeger, U. S. Schubert, Beyond gene transfection with methacrylate-based polyplexesthe influence of the amino substitution pattern ", Bioconjugate Chem. 2018 , 29 , 2181-2194.
A. Koeberle, O. Werz, Natural products as inhibitors of prostaglandin E2 and pro-inflammatory 5-lipoxygenase-derived lipid mediator biosynthesis ", Biotechnol. Adv. 2018 , 36 , 1709-1723.
L. Volkmann, M. Köhler, F. H. Sobotta, M. T. Enke, J. C. Brendel, F. H. Schacher, Poly(2-acrylamidoglycolic acid) (PAGA): Controlled polymerization using RAFT and chelation of metal cations ", Macromolecules 2018 , DOI: 10.1021/acs.macromol.1028b01260.
J. Zhang, B. Farias-Mancilla, M. Destarac, U. S. Schubert, D. J. Keddie, C. Guerrero-Sanchez, S. Harrisson, Asymmetric copolymers: Synthesis, properties, and applications of gradient and other partially segregated copolymers ", Macromol. Rapid Commun. 2018 , 39 , 1800357.
S. Miwa, R. Takahashi, C. Rössel, S. Matsumoto, S. Fujii, J. H. Lee, F. H. Schacher, K. SakuraiCore–shell–corona micelles from a polyether-based triblock terpolymer: Investigation of the pH-dependent micellar structure Langmuir 2018 , 34 , 7813-7820.
C. Guerrero‐Sanchez, J. Zhang, J. Vitz, U. S. SchubertHigh-throughput synthesis of polymers Encyclopedia of Polymer Science and Technology , 2018 , doi:10.1002/0471440264.pst0471440668.
2017
A. T. Press, A. Ramoji, M. vd Lühe, A. C. Rinkenauer, J. Hoff, M. Butans, C. Rössel, C. Pietsch, U. Neugebauer, F. H. Schacher, M. Bauer, "Cargocarrier interactions significantly contribute to micellar conformation and biodistribution ", NPG Asia Materials 2017 , 9 , e444.
M. Pröhl, S. Seupel, P. Sungur, S. Höppener, M. Gottschaldt, J. C. Brendel, U. S. Schubert, "The influence of the grafting density of glycopolymers on the lectin binding affinity of block copolymer micelles ", Polymer 2017 , 133 , 205-212.
