Alle Einträge erweitern
2025
M. Streiber, N. E. Göppert, V. Bachmann, B. Schulze, R. Gläßer, I. Anufriev, P. Schädel, I. Nischang, C. Weber, O. Werz, U. S. Schubert, A. Traeger Tailoring cationic poly(2-oxazoline)s: Minimizing toxicity and immunogenic response for biological applicationsExterner Link Mater. Today Chem. 2025 , 44 , 102549.
I. Anufriev, T. Klein, S. Hoeppener, J. C. Brendel, I. Nischang Supramolecular polymer bottlebrushes: In situ assessment of noncovalent assemblies in human serum by analytical ultracentrifugationExterner Link Macromol. Rapid Commun . 2025 , 46 , 2400890.
V. H. P. Carrillo, J. J. Whittaker, C. Wiedemann, J. M. Harder, T. Lohr, A. K. Jamithireddy, M. Dajka, B. Goretzki, B. Joseph, A. Guskov, N. J. Harmer, U. Holzgrabe, U. A. Hellmich Structure and dynamics of macrophage infectivity potentiator proteins from pathogenic bacteria and protozoans bound to fluorinated pipecolic acid inhibitorsExterner Link J. Med. Chem. 2025 , 68 , 5926-5941.
Y. F. Chen, F. Arendt, H. Bornhoeft, A. S. S. de Camargo, J. Deubener, A. Diegeler, S. Gogula, A. T. C. Jaimes, S. Kempf, M. Kilo, R. Limbach, R. Mueller, R. Niebergall, Z. W. Pan, F. Puppe, S. Reinsch, G. Schottner, S. Stier, T. Waurischk, L. Wondraczek, M. Sierka Ontology-based digital infrastructure for data-driven glass developmentExterner Link Adv. Eng. Mat. 2025 , 27 , 2401560.
E. Colarusso, G. Lauro, M. Potenza, P. Galatello, M. L. D. Garigliota, M. G. Ferraro, M. Piccolo, M. G. Chini, C. Irace, P. Campiglia, R. K. Hoffstetter, O. Werz, A. Ramunno, G. Bifulco 5-methyl-2-carboxamidepyrrole-based novel dual mPGES-1/sEH inhibitors as promising anticancer candidatesExterner Link Arch. Pharm. (Weinheim) 2025 , 358 , e2400708.
A. Fruntke, J. Hulsmann, L. H. Skodda, B. Blumbott, M. Godmann, A. Koschella, T. Heinzel, T. Heinze, T. Wilke Polysaccharide-based nanoparticles prepared by dialysis: Novel drug deliveryExterner Link J. Chem. Educ. 2025 , 102 , 1169-1178.
E. Gardey, J. C. Brendel, A. Stallmach Pathophysiology of IBD as a key strategy for polymeric nanoparticle developmentExterner Link Adv. Therap. 2025 , 8 , 2400439.
S. Greiner, M. Ebrahimi, M. Rodewald, A. Urbanek, T. Meyer-Zedler, M. Schmitt, U. Neugebauer, J. Popp Characterizing metabolic shifts in septic murine kidney tissue using 2P-FLIM for early sepsis detectionExterner Link Bioengineering 2025 , 12 , 170.
H. Koceva, M. Amiratashani, P. Akbarimoghaddam, B. Hoffmann, G. Zhurgenbayeva, M. S. Gresnigt, V. R. Marcelino, C. Eggeling, M. T. Figge, M. J. Amorim, A. S. Mosig Deciphering respiratory viral infections by harnessing organ-on-chip technology to explore the gut-lung axisExterner Link Open. Biol. 2025 , 15 , 240231.
L. S. Reichel, A. Kemmer, T. Heinze, A. Traeger Design of pH-responsive and amphiphilic pullulan-based biological macromolecule for gene deliveryExterner Link Int. J. Biol. Macromol. 2025 , 301 , 140014.
L. Xiong, D. Beyer, N. Liu, T. Lehmann, S. Neugebauer, S. Schaeuble, O. Sommerfeld, P. Ernst, C. M. Svensson, S. Nietzsche, S. Scholl, T. Bruns, N. Gassler, M. H. Gräler, M. T. Figge, G. Panagiotou, M. Bauer, A. T. Press Targeting protein kinase C-α prolongs survival and restores liver function in sepsis: Evidence from preclinical modelsExterner Link Pharmacol. Res. 2025 , 212 , 107581.
T. Yalçin, P. M. Jordan, A. Olgaç, P. Dahlke, T. G. Maz, E. Banoglu, O. Werz, B. Çaliskan 2-Phenylbenzothiazoles featuring heteroaryl sulfonamide end-capping substructures as developable mPGES-1 inhibitorsExterner Link Arch. Pharm. 2025 , 358 , e2400756.
J. Schroeder, J. Westhoff, I. Vilotijević, O. Werz, S. Hoeppener, B. Löffler, D. Fischer, C. EhrhardtAnti-influenza activity of 6BIGOE: Improved pharmacological profile after encapsulation in plga nanoparticlesExterner Link Int. J. Mol. Sci. 2025 , 26 , 4235.
K. Mehmetaj, W. Foo, Z. Cseresnyés, J. Plitzko, T. A. Shaik, Q. Ain, A. Ramoji, S. Huschke, L. Xiong, A. Zipprich, J. Popp, M. T. Figge, V. Deckert, S. Schubert, N. Gassler, F. H. Schacher, M. Bauer, A. T. Press Passively targeted polymeric nanocarrier delivering STAT1 siRNA to the liver ameliorates steatohepatitis and fibrosis in the thioacetamide mouse modelExterner Link Biomaterials 2025 .
G. Lauro, M. Aliberti, M. De Nisco, S. Pedatella, G. Pepe, M. G. Basilicata, M. G. Chini, K. Fischer, R. K. Hofstetter, O. Werz, M. G. Ferraro, M. Piccolo, C. Irace, A. Saviano, P. Campiglia, A. Bertamino, C. Ostacolo, T. Ciaglia, M. Manfra, G. Bifulco Furazanopyrazine-based novel promising anticancer agents interfering with the eicosanoid biosynthesis pathways by dual mPGES-1 and sEH inhibitionExterner Link Eur. J. Med. Chem. 2025 , 289 , 117402.
C. T. Holick, T. Klein, C. Mehnert, F. Adermann, I. Anufriev, M. Streiber, L. Harder, A. Traeger, S. Hoeppener, C. Franke, I. Nischang, S. Schubert, U. S. Schubert Poly(2-ethyl-2-oxazoline) (POx) as poly(ethylene glycol) (PEG) lipid substitute for lipid nanoparticle formulationsExterner Link Small 2025 , 21 , 2411354.
S. Bekemeier, C. R. Caldeira Rêgo, H. L. Mai, U. Saikia, O. Waseda, M. Apel, F. Arendt, A. Aschemann, B. Bayerlein, R. Courant, G. Dziwis, F. Fuchs, U. Giese, K. Junghanns, M. Kamal, L. Koschmieder, S. Leineweber, M. Luger, M. Lukas, J. Maas, J. Mertens, B. Mieller, L. Overmeyer, N. Pirch, J. Reimann, S. Schröck, P. Schulze, J. Schuster, A. Seidel, O. Shchyglo, M. Sierka, F. Silze, S. Stier, M. Tegeler, J. F. Unger, M. Weber, T. Hickel, J. Schaarschmidt Advancing digital transformation in material science: The role of workflows within the MaterialDigital initiativeExterner Link Adv. Eng. Mat. 2025 , 27 , 2402149.
C. Ventura-Hunter, D. Pretzel, C. Kellner, S. Hoeppener, N. C. Roesner, P. Quintana-Owen, U. S. Schubert, G. Ayora-Talavera, E. Saldívar-Guerra, S. Fedeli, C. Guerrero-Sanchez Amphiphilic block copolymer conjugated with cell-penetrating-peptides derived from Influenza A H1N1 virus as a biocompatible scaffold for enhanced cell-uptakeExterner Link Eur. Polym. J. 2025 , 229 , 113876.
M. Kötzsche, J. Egger, A. Dzierza, S. Reichel, I. Nischang, A. Traeger, D. Fischer, K. Peneva Making the negative positive – fluorination of indole as efficient strategy to improve guanidinium-containing gene carriersExterner Link J. Mater. Chem. B 2025 .
S. Zhang, K. Schlabach, V. H. P. Carrillo, A. Ibrahim, A. Komor, R. Mukherji, S. Chowdhury, L. Reimer, F. Trottmann, C. Hertweck, U. A. Hellmich, P. StallforthA chemical radar allows bacteria to detect and kill predatorsExterner Link Cell 2025 , 118 , 2495-2504.e20.
S. Sunoqrot, S. Abusulieh, I. Anufriev, P. Dahlke, P. M. Jordan, E. Al-Shalabi, C. T. Holick, S. Hoeppener, I. Nischang, O. Werz, S. Schubert, U. S. SchubertMild oxidation of plant polyphenols yields modular nanoparticle-forming materials with drug loading capabilitiesExterner Link Macromol. Biosci. 2025 , 25 , 2400529.
A. Wallbraun, T. Wilke Vom erkrankten Organ zur gezielten Behandlung – Medikamenten-Taxis aus Nano-Kunststoffen im Unterricht untersuchenUnterricht Chemie 2025 , 207 , 36-42.
I. Parchmann, H. Rautenstrauch, T. Wilke, P. Wlotzka Medikamente und ihre Wirkstoffe - ein Thema auch für den ChemieunterrichtUnterricht Chemie 2025 , 207 , 2-8.
P. Wlotzka, T. Wilke Wirkstoffeigenschaften optimieren dank Polyethylenglyco l– Struktur-Eigenschaftsbeziehungen von KunststoffenUnterricht Chemie 2025 , 207 , 30-34.
T. Koswig, J. Kimmig, A. Vollrath, A. Träger, S. Zechel, U. S. Schubert Automatisierung, Robotik und künstliche Intelligenz - Auf dem digitalen Weg zu neuen MedikamentenUnterricht Chemie 2025 , 207 , 9-11.
X. Wang, A. Stihl, C. Höppener, J. Vitz, F. H. Schacher, V. DeckertNanoscale investigation of elasticity changes and augmented rigidity of block copolymer micelles induced by reversible core-cross-linkingExterner Link ACS Appl. Mater. Int. 2025 , 17 , 27557-27567.
G. Perçin, K. Riege, J. Fröbel, J. Metz, S. Culemann, M. Lesche, S. Reinhardt, T. Höfer, S. Hoffmann, C. Waskow Embryonic macrophages orchestrate niche cell homeostasis for the establishment of the definitive hematopoietic stem cell poolExterner Link Nat. Commun. 2025 , 16 , 4428.
L.-J. Jia, F. A. Bernal, J. Söhnlein, J. Sonnberger, I. Heineking, M. Rafiq, Z. Cseresnyés, F. Kage, F. Schmidt, R. Zaher, P. Hortschansky, S. Chaudhary, X. Gong, J. Schirawski, M. T. Figge, B. Hube, A. A. BrakhageConvergent evolution of a fungal effector enabling phagosome membrane penetrationExterner Link bioRxiv 2025 .
J. Meyer, N. E. Göppert, L. M. Stafast, C. Weber, U. S. SchubertPolyesteracetals via TBD Catalyzed Ring-Opening PolymerizationExterner Link Macromol. Rapid Commun. 2025 , e00273.
J. Schreiber, N. E. Göppert, L. M. Stafast, C. Weber, U. S. Schubert Cyclooctyne end-functionalized poly(morpholine-2,5-dione)sExterner Link Macromol. Rapid Commun. 2025 , 46 , 2400705
C. G. Hernández-Valencia, C. M. Torre-Morales, R. I. Ortiz-Huidobro, M. Ramírez-Gilly, V. Martínez-López, J. Fernández-Torres, A. Tecante, R. Sánchez-Sánchez, A. Mazzetto, C. Guerrero-Sanchez, U. S. Schubert, M. Gimeno, Y. Zamudio-CuevasIntra-articular Injectable Poly(gallic acid) and Hyaluronic Acid Reduce Inflammation and Oxidative Stress for the Treatment of OsteoarthritisExterner Link Int. J. Biological Macromol. 2025 , in press
L. Klement, J. Ismail, J. Schroeder, A. Godbole, J. Schreiber, C. Weber, Z. Cseresnyes, M. T. Figge, B. Löffler, U. S. Schubert, S. Schubert, C. Ehrhardt, C. Hoffmann Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM-I against influenza A Virus InfectionExterner Link Adv. Healthc. Mater. 2025 , e04060
J. Schroeder, J. Ismail, C. T. Holick, J. Jungwirth, L. Klement, S. Hoeppener, C. Kosan, M. Schmidtke, B. Löffler, C. Weber, U. S. Schubert, C. Hoffmann, S. Schubert, C. Ehrhardt Advancing influenza virus treatment: in vitro and ex vivo studies of PI3K inhibitor-loaded lipid nanoparticlesExterner Link Materials Today Bio 2025 , 35 , 102587.
2024
L. M. Stafast, M. Swieczkowski, P. Poudel, N. Engel, C. Yin, K. Scheuer, C. Weber, F. H. Schacher, K. D. Jandt, U. S. SchubertPOxylated stereocomplexes from PEtOx-b-PLA Diblock copolymersExterner Link Eur. Polym. J. 2024 , 221 , 113545.
Y. Köster, J. Kimmig, S. Zechel, U. S. SchubertImplementation of the Polymerfingerprint: A molecular structure representation into an artificial neural networkExterner Link STAR Protocols 2024 , 5 (2), 103055.
I. Lepori, Y. Oz, J. Im, N. Ghosh, M. Paul, U. S. Schubert, S. FedeliBioorthogonal “Click” cycloadditions: A toolkit for modulating polymers and nanostructures in living systemsExterner Link Reactions 2024 , 5 (1), 231–245.
C. Yin, J. Hemstedt, K. Scheuer, M. Struczyńska, C. Weber, U. S. Schubert, J. Bossert, K. D. Jandt The effect of stereocomplexation and crystallinity on the degradation of polylactide nanoparticlesExterner Link Nanomater . 2024 , 14 (5), 440.
M. Behnke, A. Vollrath, P. Dahlke, F. P. Larios, M. Chi, E. Tsarenko, P. M. Jordan, C. Weber, M. Dirauf, J. A. Czaplewska, B. Beringer-Siemers, S. Stumpf, C. Kellner, C. Kretzer, S. Hoeppener, I. Nischang, M. Sierka, C. Eggeling, O. Werz, U. S. Schubert, PEtOxylated polyesteramide nanoparticles for the delivery of anti-inflammatory drugsExterner Link Mater. Today Chem . 2024 , 35 , 101848.
P. Zahel, V. Bruggink, J. Hülsmann, F. Steiniger, R. K. Hofstetter, T. Heinzel, U. Beekmann, O. Werz, D. KralischExploring microemulsion systems for the incorporation of glucocorticoids into bacterial cellulose: A novel approach for anti-inflammatory wound dressingsExterner Link Pharmaceutics , 2024, 16 (4), 504.
X. Yao, S. Ehtesabi, C. Höppener, T. Deckert-Gaudig, H. Schneidewind, S. Kupfer, S. Gräfe, V. Deckert Mechanism of plasmon-induced catalysis of thiolates and the impact of reaction conditionsExterner Link J. Am. Chem. Soc. 2024 , 146 (5), 3031-3042.
T. Wilke, M. Petersen, A. Fruntke Wissen aus dem Labor unterrichtsgerecht aufbereitenExterner Link NadC . 2024 , 72 (2), 8-11.
M. Valentine, P. Rudolph, A. Dietschmann, A. Tsavou, S. Mogavero, S. Lee, E. L. Priest, G. Zhurgenbayeva, N. Jablonowski, S. Timme, C. Eggeling, S. Allert, E. Dolk, J. R. Naglik, M. T. Figge, M. S. Gresnigt, B.HubeNanobody-mediated neutralization of candidalysin prevents epithelial damage and inflammatory responses that drive vulvovaginal candidiasis pathogenesisExterner Link MBio. 2024 , 15 (3), e03409-23.
A.Seltmann, P. Carravilla, K. Reglinski, C. Eggeling, D. WaitheNeural network informed photon filtering reduces fluorescence correlation spectroscopy artifactsExterner Link Biophys. J . 2024 , 123 (6), 745-755.
K. K.Schwickert, M. Glitscher, D. Bender, R. Murra, K. Schwickert, S. Pfalzgraf, T. Schirmeister, U. A. Hellmich, E. HildtLate stages of the Zika virus life cycle are impaired by a selective TRPML2 agonistExterner Link bioRxiv 2024 , 578205.
S. Mikutis, S. Lawrinowitz, C. Kretzer, L. Dunsmore, L. Sketeris, T. Rodrigues, O. Werz, G. J. L. Bernardes Machine learning uncovers natural product modulators of the 5-lipoxygenase pathway and facilitates the elucidation of their biological mechanismsExterner Link ACS Chem. Biol . 2024 , 19 (1), 217-229.
P. P. Mapfumo, J. I. Solomun, F. Becker, E. Moek, M. N. Leiske, L. K. Rudolph, J. C. Brendel, A. Traeger Vitamin B3 containing polymers for nanodeliveryExterner Link Macromol. Biosci . 2024 , 24, 2400002.
P. P. Mapfumo, L. S. Reichel, S. Hoeppener, A. Traeger Improving gene delivery: Synergy between alkyl chain length and lipoic acid for PDMAEMA hydrophobic copolymersExterner Link Macromol. Rapid Commun . 2024 , 45 (7), 2300649.
P. Manhas, C. Cokca, R. Sharma, K. Peneva, N. Wangoo, D. Sharma, R. K. SharmaChitosan functionalized doxorubicin loaded poly(methacrylamide) based copolymeric nanoparticles for enhanced cellular internalization and in vitro anticancer evaluationExterner Link Int. J. Biol. Macromol . 2024 , 259 , 129242.
K. Leer, L. S. Reichel, M. Wilhelmi, J. C. Brendel, A. Traeger Tailoring gene transfer efficacy through the arrangement of cationic and anionic blocks in triblock copolymer micellesExterner Link ACS Macro Lett . 2024 , 13 (2), 158-165.
K. Leer, L. S. Reichel, J. Kimmig, F. Richter, S. Hoeppener, J. C. Brendel, S. Zechel, U. S. Schubert, A. Traeger Optimization of mixed micelles based on oppositely charged block copolymers by machine learning for application in gene deliveryExterner Link Small 2024 , 20 (6), 2306116.
K. Kowalczuk, A. Dasgupta, F. Páez Larios, H. F. Ulrich, V. Wegner, J. C. Brendel, C. Eggeling, A. S. Mosig, F. H. Schacher Self-degrading multifunctional PEG-based hydrogels—Tailormade substrates for cell cultureExterner Link Macromol. Biosci . 2024 , 24 (5), 2300383.
S. König, J. Schroeder, S. Nietzsche, T. Heinekamp, A. A. Brakhage, R. Zell, B. Löffler, C. Ehrhardt The influenza A virus promotes fungal growth of Aspergillus fumigatus via direct interaction in vitroExterner Link Microbes Infect . 2024 , 26 (3), 105264.
J. Joseph, L. Spantzel, M. Ali, J. D. Moonnukandathil , S. Unger, K. Reglinski, C. Krafft, A.-D. Müller, C. Eggeling, R. Heintzmann, M. Börsch, A. T. Press, D. Täuber Nanoscale chemical characterization of secondary protein structure of F-Actin using mid-infrared photoinduced force microscopy (PiF-IR)Externer Link Spectrochim Acta. A. Mol. Biomol. Spectrosc. 2024 , 306 , 123612.
P. M. Jordan, K. Günther, V. Nischang, Y. Ning, S. Deinhardt-Emmer, C. Ehrhardt, O. Werz Influenza A virus selectively elevates prostaglandin E(2) formation in pro-resolving macrophagesExterner Link Iscience 2024 , 27 (1), 108775.
J. Ismail, L. C. Klepsch, P. Dahlke, E. Tsarenko, A. Vollrath, D. Pretzel, P. M. Jordan, K. Rezaei, J. A. Czaplewska, S. Stumpf, B. Beringer-Siemers, I. Nischang, S. Hoeppener, O. Werz, U. S. Schubert PEG-Lipid-PLGA hybrid particles for targeted delivery of anti-inflammatory drugsExterner Link Pharmaceutics 2024 , 16 (2), 187.
E. Gardey, Z. Cseresnyes, F. H. Sobotta, J. Eberhardt, D. Haziri, P. C. Grunert, M. T. Kuchenbrod, F. V. Gruschwitz, S. Hoeppener, M. Schumann, N. Gaßler, M. T. Figge, A. Stallmach, J. C. Brendel Selective uptake into inflamed human intestinal tissue and immune cell targeting by wormlike polymer micellesExterner Link Small 2024 , 20 (21), e2306482.
B. Farias-Mancilla, A. Balestri, J. Zhang, H. Frielinghaus, D. Berti, C. Montis, M. Destarac, U. S. Schubert, C. Guerrero-Sanchez, S. Harrisson, B. Lonetti Morphology and thermal transitions of self-assembled NIPAM-DMA copolymers in aqueous media depend on copolymer composition profileExterner Link J. Colloid Interface Sci . 2024 , 662 , 99-108.
C. Ehle, A. Iyer-Bierhoff, Y. Wu, S. Xing, M. Kiehntopf, A. S. Mosig, M. Godmann, T. Heinzel Downregulation of HNF4A enables transcriptomic reprogramming during the hepatic acute-phase responseExterner Link Commun. Biol. 2024 , 7 (1), 589.
C. Cerchia, L. Küfner, O. Werz, A. Lavecchia Identification of selective 5-LOX and FLAP inhibitors as novel anti-inflammatory agents by ligand-based virtual screeningExterner Link Eur. J. Med. Chem . 2024 , 263 , 115932.
M. Behnke, C. T. Holick, A. Vollrath, S. Schubert, U. S. Schubert Knowledge-based design of multifunctional polymeric nanoparticlesExterner Link Handb. Exp. Pharmacol . 2024 , 284 , 3-26.
J. De Breuck, M. Streiber, M. Ringleb, D. Schröder, N. Herzog, U. S. Schubert, S. Zechel, A. Traeger, M. N. LeiskeAmino-acid-derived anionic polyacrylamides with tailored hydrophobicity–physicochemical properties and cellular interactionsExterner Link ACS Polym. 2024 , 4 (3), 222–234.
R. Kampes, A. Chettri, M. Sittig, G. Yang, S. Zechel, S. Kupfer, M. D. Hager, B. Dietzek-Ivanšić, U. S. SchubertAn iridium complex as bidentate halogen bond-based anion receptor featuring an increased optical responseExterner Link Chem. Open 2024 , 13 , e202300183.
R. Pérez-Isidoro, A. G. Valdez-Lara, A. J. Díaz-Salazar, S. Hoeppener, C. Guerrero-Sánchez, P. Quintana-Owen, J. C. Ruiz-Suárez, U. S. Schubert, G. Ayora-Talavera, M. A. De Jesús-Téllez, E. Saldívar-GuerraBiophysical investigation of liposome systems decorated with bioconjugated copolymers in the presence of amantadineExterner Link J. Mater. Chem . B 2024 , 12 , 5823–5837.
T. Schuett, P. Endres, J. Kimmig, R. Lorenz, Y. Köster, S. Stumpf, S. Zechel, U. S. SchubertAutomated screening of precipitation polymerizations and evaluation using image recognition for divinylbenzene and methacrylic acidExterner Link J. Appl. Polym. Sci. 2024 , 141 (38), e55985.
L. Simon, L. S. Reichel, B. T. Benkhaled, J.-M. Devoisselle, S. Catrouillet, J. Eberhardt, S. Hoeppener, U. S. Schubert, J. C. Brendel, M. Morille, V. Lapinte, A. TraegerPolyoxazolines with cholesterol lipid anchor for fast intracellular deliveryExterner Link Macromol. Biosci. 2024, 24 , 2400148.
J. Alex, C. Weber, C. Guerrero-Sanchez, U. S. SchubertRecent developments in synthetic approaches for macromolecular prodrugsExterner Link Progr. Polym. Sci. 2024 , 155 , 101855.
E. Tsarenko, N. E. Goeppert, P. Dahlke, M. Behnke, G. Gangapurwala, B. Beringer-Siemers, L. Jaepel, C. Kellner, D. Pretzel, J. A. Czaplewska, A. Vollrath, P. M. Jordan, C. Weber, O. Werz, U. S. Schubert, I. NischangUnveiling the power of liquid chromatography in examining a library of degradable poly(2-oxazoline)s in nanomedicine applicationsExterner Link J. Mater. Chem. B 2024 , 12 , 11926-11938.
R. Alonso-Roman, A. S. Mosig, M. T. Figge, K. Papenfort, C. Eggeling, F. H. Schacher, B. Hube, M. S. Gresnigt Organ-on-chip models for infectious disease researchExterner Link Nat. Microbiol 2024 , 9 , 891-904.
I. Anufriev, J. Debbeler, A. Traeger, I. Nischang Analysis of Macromolecular Systems as Enabler for Energy and Life Science ApplicationsExterner Link Macromol. Chem. Phys. 2024 , 225 , 17.
V. Bachmann, P. Schädel, J. Westhoff, M. Peric, F. Schömberg, A. L. Skaltsounis, S. Höppener, T. Pantsar, D. Fischer, I. Vilotijevic, O. Werzae Bromo-substituted indirubins for inhibition of protein kinase-mediated signalling involved in inflammatory mediator release in human monocyteExterner Link s Bioorg. Chem. 2024 , 149 , 107470.
A. Chettri, L. I. Kaberov, N. Klosterhalfen, S. Perera, M. Jamshied, F. H. Schacher, B. Dietzek-Ivansic Poly(2-Oxazoline) amphiphilicity tunes the excited-state proton transfer of pyrenol-based polyphotoacidsExterner Link s Chem. Eur. J. 2024 , 30 , e202401047.
A. Dasgupta, A. Koerfer, B. Kokot, I. Urbancic, C. Eggeling, P. Carravilla Effects and avoidance of photoconversion-induced artifacts in confocal and STED microscopyExterner Link Nat. Methods 2024 , 21 , 1171–1174.
A. Feile, V. D. Wegner, M. Raasch, A. S. Mosig Immunocompetent intestine-on-chip model for analyzing gut mucosal immune responsesExterner Link J. Vis. Exp. 2024 , 207 , e66603.
E. Gardey, J. Eberhardt, S. Hoeppener, F. H. Sobotta, J. C. Brendel, A. Stallmach Anti-inflammatory potential of beclometasone-loaded filomicelles on activated human monocytesExterner Link Macromol. Biosci . 2024 , 24 , 2400179.
A. P. Grimm, M. Plank, A. Stihl, C. W. Schmitt, D. Voll, F. H. Schacher, J. Lahann, P. Théato Inverse vulcanization of activated norbornenyl esters-a versatile platform for functional sulfur polymersExterner Link Angew. Chem. Int. Ed. 2024 , 63 , e202411010.
K. Günther, C. Ehrhardt, O. Werz, P. M. Jordan Protocol for lipid mediator profiling and phenotyping of human M1- and M2-monocyte-derived macrophages during host-pathogen interactionsExterner Link STAR Protoc. 2024 , 5 (3), 103142.
C. Höppener, J. Aizpurua, H. Chen, S. Gräfe, A. Jorio, S. Kupfer, Z. L. Zhang, V. Deckert Tip-enhanced Raman scatteringExterner Link Nat. Rev. Method. Prim. 2024 , 4 , 47.
L. J. Jia, K. González, T. Orasch, F. Schmidt, A. A. Brakhage Manipulation of host phagocytosis by fungal pathogens and therapeutic opportunitiesExterner Link Nat. Microbiol 2024 , 9 , 2216-2231.
R. Kampes, A. Chettri, M. Sittig, G. J. Yang, S. Zechel, S. Kupfer, M. D. Hager, B. Dietzek-Ivansic, U. S. Schubert An iridium complex as bidentate halogen bond-based anion receptor featuring an increasedoptical responseExterner Link ChemistryOpen 2024 , 13 , e202300183.
Y. Köster, J. Kimmig, S. Zechel, U. S. Schubert Protocol for creating representations of molecular structures using a polymer-specific decoderExterner Link STAR Protoc. 2024 , 5 (2), 103055.
S. Kröller, J. Schober, N. Krieg, S. Dennhardt, W. Pirschel, M. Kiehntopf, E. M. Conway, S. M. Coldewey The role of the n-terminal domain of thrombomodulin and the potential of recombinant human thrombomodulin as a therapeutic intervention for shiga toxin-induced hemolytic-uremic syndromeExterner Link Toxins 2024 , 16 (9), 409.
N. Liu, M. Sonawane, O. Sommerfeld, C. M. Svensson, M. T. Figge, R. Bauer, S. J. Bischoff, M. Bauer, M. F. Osuchowski, A. T. Press Metamizole outperforms meloxicam in sepsis: insights on analgesics, survival and immunomodulation in the peritoneal contamination and infection sepsis modelExterner Link Front. Immunol. 2024 , 15 , 1432307.
K. Majzner, T. Deckert-Gaudig, M. Baranska, V. Deckert DOX-DNA interactions on the nanoscale: In situ studies using tip-enhanced raman scatteringExterner Link Anal. Chem. 2024 , 96 (22), 8905-8913.
P. P. Mapfumo, L. S. Reichel, T. André, S. Hoeppener, L. K. Rudolph, A. Traeger Optimizing biocompatibility and gene delivery with DMAEA and DMAEAm: A niacin-derived copolymer approachExterner Link Biomacromolecules 2024 , 25 (8), 4749-4761.
P. P. Mapfumo, L. S. Reichel, K. Leer, J. Egger, A. Dzierza, K. Peneva, D. Fischer, A. Traeger Harnessing guanidinium and imidazole functional groups: A dual-charged polymer strategy for enhanced gene deliveryExterner Link ACS Macro Lett. 2024 , 13 (8), 1000-1007.
T. G. Maz, P. Dahlke, A. G. Ergül, A. Olgaç, P. M. Jordan, B. Çaliskan, O. Werz, E. Banoglu Novel 1,3,4-oxadiazole derivatives as highly potent microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitorsExterner Link Bioorg. Chem. 2024 , 147 , 107383.
R. Mincigrucci, E. Paltanin, J. S. Pelli-cresi, F. Gala, E. Pontecorvo, L. Foglia, D. De Angelis, D. Fainozzi, A. Gessini, D. S. P. Molina, O. Stranik, F. Wechsler, R. Heintzmann, J. Rothhardt, L. Loetgering, G. Ruocco, F. Bencivenga, C. Masciovecchio Structured illumination microscopy with extreme ultraviolet pulsesExterner Link Opt. Express 2024 , 32 (17), 30813-30823.
R. H. D. Miora, M. Senftleben, S. Abrahamsson, E. Rohwer, R. Heintzman, G. Bosman Experimental validation of numerical point spread function calculation including aberration estimationExterner Link Opt. Express 2024 , 32 (12), 21887-21908.
S. Schlicht, J. Campbell, A. Weber, J. Westhoff, D. Volodkin, D. Fischer, D. Drummer, A. Vikulina Vaterite-based in situ surface modification and process-dependent biocompatibility of laser sintered polypropyleneExterner Link J. Mater. Res. Technol-JMRT 2024 , 32 , 3447-3455.
K. K. Schwickert, M. Glitscher, D. Bender, N. I. Benz, R. Murra, K. Schwickert, S. Pfalzgraf, T. Schirmeister, U. A. Hellmich, E. Hildt Zika virus replication is impaired by a selective agonist of the TRPML2 ion channelExterner Link Antivir. Res. 2024 , 228 , 105940.
D. Shrestha, Y. Bahasoan, C. Eggeling Cellular output and physicochemical properties of the membrane-derived vesicles depend on chemical stimulantsExterner Link ACS Appl. Mater. Interfaces. 2024 , 16 (37), 48982-48992.
H. F. Ulrich, F. V. Gruschwitz, T. Klein, N. Ziegenbalg, D. T. N. Anh, S. Fujii, S. Hoeppener, K. Sakurai, J. C. Brendel Influence of polymer side chain size and backbone length on the self-assembly of supramolecular polymer bottlebrushesExterner Link Chem. Eur. J. 2024 , 30, 11.
K. Günther, V. Nischang, Z. Cseresnyés, T. Krüger, D. Sheta, Z. Abboud, T. Heinekamp, M. Werner, O. Kniemeyer, A. Beilhack, M. T. Figge, A. A. Brakhage, O. Werz, P. M. Jordan Aspergillus fumigatus-derived gliotoxin impacts innate immune cell activation through modulating lipid mediator production in macrophagesExterner Link Immunology 2024.
J. Plitzko, T. Köhler, T. Meyer-Zedler, S. Schubert, M. Schmitt, J. Popp Hydrolyzation-free characterization of acetalated dextran via 2D correlated raman spectroscopyExterner Link J. Raman Spectrosc. 2024 .
C. Schultz, T. Wegner, C. Heusel, T. Gallagher, Y. Zheng, M. Werner, S. V. Wegner, T. Meyer-Zedler, O. Werz, M. Schmitt, J. Popp, F. Glorius Alkyne-tagged imidazolium-based membrane cholesterol analogs for Raman imaging applicationsExterner Link Chem. Sci. 2024 , 15 , 14323-14335.
N. Engel, M. Dirauf, J. A. Czaplewska, I. Nischang, M. Gottschaldt, U. S. Schubert Determination of ω-end functionalities in tailored poly(2-alkyl-2-oxazoline)s by liquid chromatography and mass spectrometryExterner Link R. Soc. Open Sci. 2024 , 11 , 231008.
N. t. Horst, J. Dietrich, T. Wilke Digitalchemlab ─digital and complexity-differentiated learning modules in an out of school student laboratoryExterner Link J. Chem. Educ. 2024 , 101 (5), 1810–1821.
G. De Angelis, J. Abramo, M. Miasnikova, M. Taubert, C. Eggeling, F. Reina Homogeneous large field-of-view and compact iSCAT-TIRF setup for dynamic single molecule measurementsExterner Link Opt. Express 2024 , 32 (26), 46607-46620.
A. G. Ergul, P. M. Jordan, P. Dahlke, N. B. Bal, A. Olgac, O. Uludag, O. Werz, B. Caliskan, E. BanogluNovel benzimidazole derivatives as potent inhibitors of microsomal prostaglandin E(2) synthase 1 for the potential treatment of inflammation, pain, and feverExterner Link J. Med. Chem. 2024 , 67 (23), 21143-21162.
C. Haring, J. Schroeder, J. Jungwirth, B. Loffler, A. Henke, B. Engert, C. Ehrhardt ProcCluster® and procaine hydrochloride inhibit the replication of influenza A virus in vitroExterner Link Front Microbiol 2024 , 15 , 1422651.
S. König, J. Schroeder, T. Heinekamp, A. A. Brakhage, B. Löffler, B. Engert, C. Ehrhardt ProcCluster® and procaine hydrochloride inhibit the growth of Aspergillus species and exert antimicrobial properties during coinfection with influenza A viruses and A. fumigatus in vitroExterner Link Front. Cell. Infect. Microbiol. 2024 , 14 , 1445428.
A. Abou-Kandil, S. Tröger-Görler, A. Pschibul, T. Krüger, M. Rosin, F. Schmidt, P. Akbarimoghaddam, A. Sarkar, Z. Cseresnyés, Y. Shadkchan, T. Heinekamp, M. H. Gräler, A. E. Barber, G. Walther, M. T. Figge, A. A. Brakhage, N. Osherov, O. Kniemeyer The proteomic response of Aspergillus fumigatus to amphotericin B (AmB) reveals the involvement of the RTA-like protein RtaA in AmB resistanceExterner Link microLife 2024 , 6.
E. Dietel, T. WilkeSituationales Interesse an medizinischen Kontexten im Chemieunterricht: Pilotstudie, in Frühe naturwissenschaftliche Bildung (Ed.: H. van Vorst), GDCP,Externer Link Essen, 2024 , pp. 770–773.
C. Visser, F. Rivieccio, T. Krüger, F. Schmidt, Z. Cseresnyés, M. Rohde, M. T. Figge, O. Kniemeyer, M. G. Blango, A. A. Brakhage Tracking the uptake of labelled host-derived extracellular vesicles by the human fungal pathogen Aspergillus fumigatusExterner Link microLife 2024 , 5.
J. E. Márquez-Castro, A. Licea-Claverie, C. Guerrero-Sánchez, E. R. MéndezSurface modification of gold nanorods (GNRDs) using double thermo-responsive block copolymers: Evaluation of self-assembly and stability of nanohybridsExterner Link Polymers 2024 , 16 (23), 3293.
2023
E. Quansah, E. Gardey, A. Ramoji, T. Meyer-Zedler, B. Goehrig, A. Heutelbeck, S. Hoeppener, M. Schmitt, M. Waldner, A. Stallmach, J. PoppIntestinal epithelial barrier integrity investigated by label-free techniques in ulcerative colitis patientsExterner Link Sci. Rep. 2023 , 13 , 2681.
D. FischerSustainability in drug and nanoparticle processingExterner Link Springer Berlin Heidelberg, Berlin, Heidelberg, 2023 , 284 , 45-68.
I. Anufriev, S. Hoeppener, I. NischangPEG-Lipids: Quantitative study of unimers and aggregates thereof by the methods of molecular hydrodynamicsExterner Link Anal. Chem. 2023 , 95 , 10795-10802.
L.-J. Jia, M. Rafiq, L. Radosa, P. Hortschansky, C. Cunha, Z. Cseresnyés, T. Krüger, F. Schmidt, T. Heinekamp, M. Straßburger, B. Löffler, T. Doenst, J. F. Lacerda, A. Campos, M. T. Figge, A. Carvalho, O. Kniemeyer, A. A. BrakhageAspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathwayExterner Link Cell Host Microbe 2023 , 31 (3), 373-388.e310.
L. I. Kaberov, M. Sittig, A. Chettri, A. Ibrahim, B. Dietzek-Ivanšić, F. H. SchacherMulti-stimuli-responsive copolymers based on 1-pyrenol polyphotoacidsExterner Link Polym. Chem. 2023 , 14 , 3453-3464.
H. Lindemann, M. Kühne, A. Koschella, M. Godmann, T. Heinzel, T. Heinze, "HDACi delivery systems based on cellulose valproate nanoparticles", in HDAC/HAT function assessment and inhibitor development: Methods and protocols (Ed.: O. H. Krämer)Externer Link Springer US , 2023 , 195-205.
S. Wang, P. Poudel, F. H. Schacher, L. I. KaberovDouble stimuli-responsive azobenzene containing poly(2-oxazoline)s: synthesis, light, and temperature-responsive behaviorExterner Link Polym. Chem. 2023 , 14 , 3381-3391.
F. Borner, S. Pace, P. M. Jordan, J. Gerstmeier, M. Gomez, A. Rossi, N. C. Gilbert, M. E. Newcomer, O. WerzAllosteric activation of 15-lipoxygenase-1 by boswellic acid Induces the lipid mediator class switch to promote resolution of inflammationExterner Link Adv. Sci. 2023 , 10 , 2205604.
M. Behnke, P. Klemm, P. Dahlke, B. Shkodra, B. Beringer-Siemers, J. A. Czaplewska, S. Stumpf, P. M. Jordan, S. Schubert, S. Hoeppener, A. Vollrath, O. Werz, U. S. SchubertEthoxy acetalated dextran nanoparticles for drug delivery: A comparative study of formulation methodsExterner Link Int. J. Pharma.: X 2023 , 5 , 100173.
M. Kühne, S. Hofmann, H. Lindemann, Z. Cseresnyés, A. Dzierza, D. Schröder, M. Godmann, A. Koschella, C. Eggeling, D. Fischer, M. T. Figge, T. Heinze, T. HeinzelAnalysis of HDACi-coupled nanoparticles: Opportunities and challenges.Externer Link Methods Mol. Biol. 2023 , 2589 , 129-144.
T. Bellmann, J. Thamm, U. Beekmann, D. Kralisch, D. FischerIn situ formation of polymer microparticles in bacterial nanocellulose using alternative and sustainable solvents to incorporate lipophilic drugsExterner Link Pharmaceutics 2023 , 15 , 559.
W. Foo, Z. Cseresnyes, C. Rossel, Y. F. Teng, A. Ramoji, M. Z. Chi, W. Hauswald, S. Huschke, S. Hoeppener, J. Popp, F. H. Schacher, M. Sierka, M. T. Figge, A. T. Press, M. BauerTuning the corona-core ratio of polyplex micelles for selective oligonucleotide delivery to hepatocytes or hepatic immune cellsExterner Link Biomaterials 2023 , 294 , 122016.
A. T. Frawley, K. G. Leslie, V. Wycisk, S. Galiani, D. Shrestha, C. Eggeling, H. L. AndersonA photoswitchable solvatochromic dye for probing membrane ordering by RESOLFT super-resolution microscopyExterner Link ChemPhysChem 2023 , 24 , e202300125.
A. Fruntke, M. Behnke, L. M. Stafast, T. Trader, E. Dietel, A. Vollrath, C. Weber, U. S. Schubert, T. WilkeTargeted drug delivery: Synthesis of smart nanocarriers for school chemistry educationExterner Link J. Chem. Educ. 2023 , 100 (2), 751-759.
S. Galiani, C. Eggeling, K. ReglinskiSuper-resolution microscopy and studies of peroxisomesExterner Link Biol. Chem. 2023 , 404 , 87-106.
R. Gerst, Z. Cseresnyes, M. T. FiggeJIPipe: Visual batch processing for ImageJExterner Link Nat. Meth. 2023 , 20 , 168-169.
M. Goldmann, F. Schmidt, Z. Cseresnyes, T. Orasch, S. Jahreis, S. Hartung, M. T. Figge, M. von Lilienfeld-Toal, T. Heinekamp, A. A. BrakhageThe lipid raft-associated protein stomatin is required for accumulation of dectin-1 in the phagosomal membrane and for full activity of macrophages against Aspergillus fumigatusExterner Link mSphere 2023 , 8 , e00523-22.
K. Gonzalez, G. Gangapurwala, J. Alex, A. Vollrath, Z. Cseresnyes, C. Weber, J. A. Czaplewska, S. Hoeppener, C. M. Svensson, T. Orasch, T. Heinekamp, C. Guerrero-Sanchez, M. T. Figge, U. S. Schubert, A. A. BrakhageTargeting of phagolysosomes containing conidia of the fungus Aspergillus fumigatus with polymeric particlesExterner Link Appl. Microbiol. Biotechnol. 2023 , 107 , 819-834.
F. Hausig-Punke, G. Dekevic, F. H. Sobotta, J. I. Solomun, F. Richter, D. Salzig, A. Traeger, J. C. BrendelEfficient transfection via an unexpected mechanism by near neutral polypiperazines with tailored response to endosomal pHExterner Link Macromol. Biosci. 2023 , 23 , 2200517.
C. Hoppener, J. K. Elter, F. H. Schacher, V. DeckertInside block copolymer micelles-tracing interfacial influences on crosslinking efficiency in nanoscale confined spacesExterner Link Small 2023 , 19 , 2206451.
V. Krauth, F. Bruno, S. Pace, P. M. Jordan, V. Temml, M. P. Romano, H. Khan, D. Schuster, A. Rossi, R. Filosa, O. WerzHighly potent and selective 5-lipoxygenase inhibition by new, simple heteroaryl-substituted catechols for treatment of inflammationExterner Link Biochem. Pharmacol. 2023 , 208 , 115385.
V. D. Lechuga-Islas, D. M. Sanchez-Cerrillo, S. Stumpf, R. Guerrero-Santos, U. S. Schubert, C. Guerrero-SanchezThermo-responsive polymer catalysts for polyester recycling processes: switching from homogeneous catalysis to heterogeneous separationsExterner Link Polym. Chem. 2023 , 14 , 1893-1904.
V. D. Lechuga-Islas, M. Trejo-Maldonado, I. Anufriev, I. Nischang, I. Terzioglu, J. Ulbrich, R. Guerrero-Santos, L. E. Elizalde-Herrera, U. S. Schubert, C. Guerrero-SanchezAll-aqueous, surfactant-free, and pH-driven nanoformulation methods of dual-responsive polymer nanoparticles and their potential use as nanocarriers of pH-sensitive drugsExterner Link Macromol. Biosci. 2023 , 23 , 2200262.
X. Liu, D. Wenisch, P. Dahlke, P. M. Jordan, M. A. Jakupec, C. R. Kowol, P. Liebing, O. Werz, B. K. Keppler, W. WeigandMulti-action platinum(IV) prodrugs conjugated with COX-inhibiting NSAIDsExterner Link Eur. J. Med. Chem. 2023 , 257 , 115515.
F. J. Ma, R. Kaufmann, J. Sedzicki, Z. Cseresnyes, C. Dehio, S. Hoeppener, M. T. Figge, R. HeintzmannGuided-deconvolution for correlative light and electron microscopyExterner Link PLoS One 2023 , 18 , e0282803.
T. G. Maz, B. Koc, P. M. Jordan, K. Ibis, B. Caliskan, O. Werz, E. BanogluBenzoxazolone-5-urea derivatives as human soluble epoxide hydrolase (sEH) inhibitorsExterner Link ACS Omega 2023 , 8 (2), 2445-2454.
M. Naumann, N. Arend, R. R. Guliev, C. Kretzer, I. Rubio, O. Werz, U. NeugebauerLabel-free characterization of macrophage polarization using raman spectroscopyExterner Link Int. J. Mol. Sci. 2023 , 24 (1), 824.
T. Orasch, G. Gangapurwala, A. Vollrath, K. Gonzalez, J. Alex, A. D. Luis, C. Weber, S. Hoeppener, Z. Cseresnyes, M. T. Figge, C. Guerrero-Sanchez, U. S. Schubert, A. A. BrakhagePolymer-based particles against pathogenic fungi: A non-uptake delivery of compoundsExterner Link Biomater. Adv. 2023 , 146 , 213300.
R. Perez-Isidoro, F. J. Guevara-Pantoja, C. Ventura-Hunter, C. Guerrero-Sanchez, J. C. Ruiz-Suarez, U. S. Schubert, E. Saldivar-GuerraFluidized or not fluidized? Biophysical characterization of biohybrid lipid/protein/polymer liposomes and their interaction with tetracaineExterner Link Biochim. Et Biophys. Acta - General Subjects 2023 , 1867 (2), 130287.
M. Potenza, A. Giordano, M. G. Chini, A. Saviano, C. Kretzer, F. Raucci, M. Russo, G. Lauro, S. Terracciano, I. Bruno, M. Iorizzi, R. K. Hofstetter, S. Pace, F. Maione, O. Werz, G. BifulcoIdentification of 2-aminoacyl-1,3,4-thiadiazoles as prostaglandin E2 and leukotriene biosynthesis inhibitorsExterner Link ACS Med. Chem. Lett. 2023 , 14 (1), 26-34.
L. M. Stafast, N. Engel, H. Gorls, C. Weber, U. S. SchubertEnd-functionalized diblock copolymers by mix and match of poly (2-oxazoline) and polyester building blocksExterner Link Eur. Polym. J. 2023 , 184 , 111779.
E. Tsarenko, U. S. Schubert, I. NischangNanoparticle formulation composition analysis by liquid chromatography on reversed-phase monolithic silicaExterner Link Anal. Chem. 2023 , 95 (2), 565-569.
S. Wang, P. Poudel, F. H. Schacher, L. I. KaberovStraightforward access to block and gradient light-responsive poly(2-oxazoline)s via cationic ring opening polymerization of 2-azobenzenyl-2-oxazolineExterner Link Macromol. Rapid Commun. 2023 , 44 , 2300032.
T. Wloka, S. Czich, F. Chalupa-Gantner, M. Sittig, M. Dirauf, C. Weber, M. Gottschaldt, K. Liefeith, A. Ovsianikov, B. Dietzek-Ivanšić, U. S. SchubertNew water-soluble photo-initiators for two-photon polymerization based on benzylidene cyclopentanonesExterner Link J. Photochem. Photobiol. A: Chem. 2023 , 442 , 114743.
T. X. Yang, A. Valavalkar, A. Romero-Arenas, A. Dasgupta, P. Then, A. Chettri, C. Eggeling, A. Ros, U. Pischel, B. Dietzek-IvansicExcited-state dynamics in borylated arylisoquinoline complexes in solution and in celluloExterner Link Chem. Eur. J. 2023 , 29 , e202203468.
D. Zahn, J. Landers, M. Diegel, S. Salamon, A. Stihl, F. H. Schacher, H. Wende, J. Dellith, S. DutzOptimization of magnetic cobalt ferrite nanoparticles for magnetic heating applications in biomedical technologyExterner Link Nanomaterials 2023 , 13 (10), 1673.
N. E. Göppert, A. Vollrath, L. M. Stafast, S. Stumpf, B. Schulze, S. Hoeppener, C. Weber, U. S. SchubertHow introduction of hydrolyzable moieties in pox influences particle formation – A Library approach based on block copolymers comprising polyestersExterner Link RSC Appl. Polym. 2023 , 2 , 184-195.
Y. Köster, J. Kimmig, S. Zechel, U. S. SchubertFingerprint Applicable for Machine Learning Tested on LCST Behavior of PolymersExterner Link Cell Reports Phys. Sci. 2023 , 4 (9), 101553.
J. M. Peschel, L. S. Reichel, T. Hoffmann, C. Enzensperger, U. S. Schubert, A. Traeger, M. GottschaldtModification of Branched Poly(ethylene imine) with Fructose for Selective Delivery of siRNA into Human Breast Cancer CellsExterner Link Macromol. Bioscience 2023 , 23 , 2300135.
V. Ebrahimi, T. Stephan, J. Kim, P. Carravilla, C. Eggeling, S. Jakobs & K. Y. HanAuthor Correction: Deep learning enables fast, gentle STED microscopyExterner Link Commun. Biol. 2023 , 6 , 831.
M. Ringleb, T. Schuett, S. Zechelab, U. S. SchubertBest practice for sampling in automated parallel synthesizersExterner Link Digit. Discov. 2023 , 2 , 1883-1893.
Lukas K. Peltner, L. G., F. Boerner, N. C. Gilbert, O. Werz, P. M. Jordan, Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediatorsExterner Link Cell Chem. Biol. 2023 , 30 (12), 1508 - 1524.e7.
V. Ebrahimi, T. Stephan, J. Kim, P. Carravilla, C. Eggeling, S. Jakobs, K. Y. Han Deep learning enables fast, gentle STED microscopyExterner Link Commun. Biol . 2023 , 22 .
I. Urbančič, C. Eggeling, E. Sezgin Do lipids tune B cell signaling?Externer Link Nat. Chem. Biol . 2023 , 19 , 669–670.
F. Behrendt, Z. Cseresnyés, R. Gerst, M. Gottschaldt, M. T. Figge, U. S. Schubert, Evaluation of reproducible cryogel preparation based on automated image analysis using deep learningExterner Link J. Biomed. Mater. Res., Part A 2023 , 111 (11), 1734-1749.
N. E. Göppert, S. Quader, J. F. R. Van Guyse, C. Weber, K. Kataoka, U. S. Schubert Amphiphilic poly(2-oxazoline)s with glycine-containing hydrophobic blocks tailored for panobinostat- and imatinib-loaded micellesExterner Link Biomacromolecules 2023, 24 (12), 5915-5925.
N. E. Göppert, A. Vollrath, L. M. Stafast, S. Stumpf, B. Schulze, S. Hoeppener, C. Weber, U. S. SchubertHow introduction of hydrolyzable moieties in POx influences particle formation – a library approach based on block copolymers comprising polyestersExterner Link RSC Appl. Polym. 2023 , 2 , 184-195.
C. Neu, B. Wissuwa, C. Thiemermann, S. M. ColdeweyCardiovascular impairment in Shiga-toxin-2-induced experimental hemolytic–uremic syndrome: a pilot studyExterner Link Front. Immunol. 2023 , 14 , 1252818.
H. Bae, M. Rodewald, T. Meyer-Zedler, T. W. Bocklitz, G. Matz, B. Messerschmidt, A. T. Press, M. Bauer, O. Guntinas-Lichius, A. Stallmach, M. Schmitt, J. Popp Feasibility studies of multimodal nonlinear endoscopy using multicore fiber bundles for remote scanning from tissue sections to bulk organsExterner Link Sci. Rep. 2023 , 13 (1), 13779.
P. Dahlke, L. K. Peltner, P. M. Jordan, O. Werz Differential impact of 5-lipoxygenase-activating protein antagonists on the biosynthesis of leukotrienes and of specialized pro-resolving mediatorsExterner Link Front. Pharmacol . 2023 , 14 , 1219160.
F. Dellbrügge, L. D. Jesse, A. Medyukhina, N. Liu, S. Neugebauer, M. Freißmuth, S. Höppener, M. T. Figge, H. Morrison, L. B. Riecken, A. T. PressContribution of radixin and ezrin to the maintenance of hepatocytes' excretory function in health and diseaseExterner Link Heliyon 2023 , 9 (11), e21009.
A. Fruntke, M. Behnke, E. Dietel, A. Vollrath, U. S. Schubert, T. Wilke Nanomedizin im Chemieunterricht: Zielgerichteter Wirkstofftransport mit polymeren NanopartikelnExterner Link CHEMKON 2023, 31 (6), 207-214.
G. B. Garside, M. Sandoval, S. Beronja, K. L. Rudolph Lentiviral in situ targeting of stem cells in unperturbed intestinal epitheliumExterner Link BMC Biol . 2023 , 21 (1), 6.
F. Guzmán-Lagunes, P. Wongsirichot, J. Winterburn, C. Guerrero Sanchez, C. Montiel Polyhydroxyalkanoates production: A challenge for the plastic industryExterner Link Ind. Eng. Chem. Res. 2023 , 62 (44), 18133-18158.
C. Häring, J. Jungwirth, J. Schroeder, B. Löffler, B. Engert, C. Ehrhardt The local anaesthetic procaine prodrugs ProcCluster(®) and procaine hydrochloride impair SARS-CoV-2 replication and egress in vitroExterner Link Int. J. Mol. Sci. 2023 , 24 (19), 14584.
R. Heintzmann, L. Loetgering, F. Wechsler Scalable angular spectrum propagationExterner Link Optica 2023 , 10 (11), 1407-1416.
C. Höppener, J. K. Elter, F. H. Schacher, V. Deckert Inside block copolymer micelles—Tracing interfacial influences on crosslinking efficiency in nanoscale confined spacesExterner Link Small 2023 , 19 (20), 2206451.
J. Hülsmann, H. Lindemann, J. Wegener, M. Kühne, M. Godmann, A. Koschella, S. M. Coldewey, T. Heinze, T. Heinzel Dually modified cellulose as a non-viral vector for the delivery and uptake of HDAC3 siRNAExterner Link Pharmaceutics , 2023, 15 (12), 2659.
L. Klement, J. Drube The interplay of FLT3 and CXCR4 in acute myeloid leukemia: an ongoing debateExterner Link Front. Oncol . 2023 , 13 , 1258679.
A. Koerfer, F. Reina, C. Eggeling Influence of different surface cleaning methods on STED-FCS and scanning STED-FCS calibration measurementsExterner Link J. Microsc. 2023 , 296 , 150–153.
V. Nischang, F. M. Witt, F. Börner, M. Gomez, P. M. Jordan, O. Werz Frankincense preparation promotes formation of inflammation-resolving lipid mediators by manipulating lipoxygenases in human innate immune cellsExterner Link Front. Pharmacol . 2023 , 14 , 1332628.
A. Olğaç, İ. Çapan, P. Dahlke, P. M. Jordan, O. Werz, E. Banoglu Substituted 1,2,4-triazoles as novel and selective inhibitors of leukotriene biosynthesis targeting 5-lipoxygenase-activating proteinExterner Link Acs Omega 2023 , 8 (34), 31293-31304.
I. E. Osadare, L. Xiong, I. Rubio, U. Neugebauer, A. T. Press, A. Ramoji, J. Popp Raman Spectroscopy profiling of splenic t-cells in sepsis and endotoxemia in miceExterner Link Int. J. Mol. Sci. 2023, 24 (15), 12027.
E. Quansah, T. A. Shaik, E. Çevik, X. Wang, C. Höppener, T. Meyer-Zedler, V. Deckert, M. Schmitt, J. Popp, C. Krafft Investigating biochemical and structural changes of glycated collagen using multimodal multiphoton imaging, Raman spectroscopy, and atomic force microscopyExterner Link Anal. Bioanal. Chem . 2023 , 415 (25), 6257-6267.
Z. Rao, E. Brunner, B. Giszas, A. Iyer-Bierhoff, J. Gerstmeier, F. Börner, P. M. Jordan, S. Pace, K. P. L. Meyer, R. K. Hofstetter, D. Merk, C. Paulenz, T. Heinzel, P. C. Grunert, A. Stallmach, C. N. Serhan, M. Werner, O. Werz Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolutionExterner Link Proc. Natl. Acad. Sci. U. S. A. 2023 , 120 (35), e2302070120.
C.-M. Svensson, K. Reglinski, W. Schliebs, R. Erdmann, C. Eggeling, M. T. Figge Quantitative analysis of peroxisome tracks using a Hidden Markov ModelExterner Link Sci. Rep. 2023 , 13 (1), 19694.
A. Fruntke, N. Horst, C. Bley, B. Blümbott, M. Behnke, L. M. Stafast, A. Vollrath, U.S. Schubert, T. WilkeNanomedicine in chemistry education: development of a digital learning module with real life experimentsExterner Link World J. Chem. Educ. 2023 , 11 , 97 – 103.
F. Behrendt, D. Pretzel, Z. Cseresnyés, M. Kleinsteuber, T. Wloka, L. Radosa, M. T. Figge, M. Gottschaldt, A. Brakhage, U. S. SchubertHydrophilic cryogels as potential 3D cell culture materials: Synthesis and characterization of 2-(methacrylamido) glucopyranose-based polymer scaffoldsExterner Link J. Polym. Sci. 2023 , 61 , 3039-3054.
2022
V. D. Lechuga-Islas, C. Guerrero-Sanchez, R. Guerrero-Santos, J. Vitz, U. S. SchubertHigh-throughput/high-output experimentation in polymer researchExterner Link in Macromolecular Engineering (Eds.: N. Hadjichristidis, Y. Gnanou, K. Matyjaszewski, M. Muthukumar), 2022 , pp. 1-26.
M. Trejo-Maldonado, A. Womiloju, S. Stumpf, S. Hoeppener, U. S. Schubert, L. E. Elizalde, C. Guerrero-SanchezTriazole-functionalized mesoporous materials based on poly(styrene-block-lactic acid): A morphology study of thin filmsExterner Link Polymers 2022 , 14 , 2231.
P. Klemm, J. I. Solomun, M. Rodewald, M. T. Kuchenbrod, V. G. Hänsch, F. Richter, J. Popp, C. Hertweck, S. Hoeppener, C. Bonduelle, S. Lecommandoux, A. Traeger, S. SchubertEfficient gene delivery of tailored amphiphilic polypeptides by polyplex surfingExterner Link Biomacromolecules 2022 , 23 , 4718-4733.
T. Schuett, M. Wejner, J. Kimmig, S. Zechel, T. Wilke, U. S. SchubertImprovement of high-throughput experimentation using synthesis robots by the implementation of tailor-made sensorsExterner Link Polymers 2022 , 14 , 361.
A. Balestri, B. Lonetti, S. Harrisson, B. Farias-Mancilla, J. L. Zhang, H. Amenitsch, U. S. Schubert, C. Guerrero-Sanchez, C. Montis, D. BertiThermo-responsive lipophilic NIPAM-based block copolymers as stabilizers for lipid-based cubic nanoparticlesExterner Link Colloid Surf. B-Biointerfaces 2022 , 220 , 9.
D. Beyer, J. Hoff, O. Sommerfeld, A. Zipprich, N. Gassler, A. T. PressThe liver in sepsis: molecular mechanism of liver failure and their potential for clinical translationExterner Link Mol. Med. 2022 , 28 , 15.
I. Capan, P. M. Jordan, A. Olgac, B. Caliskan, C. Kretzer, O. Werz, E. BanogluDiscovery and optimization of piperazine urea derivatives as soluble epoxide hydrolase (sEH) inhibitorsExterner Link ChemMedChem 2022 , 17 , 9.
M. Z. Chi, R. Gargouri, T. Schrader, K. Damak, R. Maalej, M. SierkaAtomistic descriptors for machine learning models of solubility parameters for small molecules and polymersExterner Link Polymers 2022 , 14 , 11.
G. Cinar, J. I. Solomun, P. Mapfumo, A. Traeger, I. NischangNanoparticle sizing in the field of nanomedicine: Power of an analytical ultracentrifugeExterner Link Anal. Chim. Acta 2022 , 1205 , 13.
A. Czapka, C. Grune, P. Schadel, V. Bachmann, K. Scheuer, M. Dirauf, C. Weber, A. L. Skaltsounis, K. D. Jandt, U. S. Schubert, D. Fischer, O. WerzDrug delivery of 6-bromoindirubin-3 '-glycerol-oxime ether employing poly(D,L-lactide-co-glycolide)-based nanoencapsulation techniques with sustainable solventsExterner Link J. Nanobiotechnol. 2022 , 20 , 21.
A. De San Luis, M. Kleinsteuber, T. Schuett, S. Schubert, U. S. SchubertMiniemulsion polymerization at low temperature: A strategy for one-pot encapsulation of hydrophobic anti-inflammatory drugs into polyester-containing nanoparticlesExterner Link J. Colloid Interface Sci. 2022 , 612 , 628-638.
N. Devi, C. Cokca, R. Sharma, M. Kumar, K. Peneva, R. K. Sharma, N. WangooFabrication of cell penetrating peptide labelled biodegradable poly (methacrylamide) nanoparticles for delivery of doxorubicin in HeLa cellsExterner Link Mater. Today Commun. 2022 , 33 , 11.
M. Dirauf, I. Muljajew, C. Weber, U. S. SchubertRecent advances in degradable synthetic polymers for biomedical applications-Beyond polyestersExterner Link Prog. Polym. Sci. 2022 , 129 , 40.
J. Drube, R. S. Haider, E. S. F. Matthees, M. Reichel, J. Zeiner, S. Fritzwanker, C. Ziegler, S. Barz, L. Klement, J. Filor, V. Weitzel, A. Kliewer, E. Miess-Tanneberg, E. Kostenis, S. Schulz, C. HoffmannGPCR kinase knockout cells reveal the impact of individual GRKs on arrestin binding and GPCR regulationExterner Link Nat. Commun. 2022 , 13 , 18.
R. Eckenstaler, A. Ripperger, M. Hauke, M. Petermann, S. A. Hemkemeyer, E. Schwedhelm, S. Ergun, M. Frye, O. Werz, A. Koeberle, H. Braun, R. A. BenndorfA thromboxane A(2) receptor-driven COX-2-dependent feedback loop that affects endothelial homeostasis and angiogenesisExterner Link Arterioscler. Thromb. Vasc. Biol. 2022 , 42 , 444-461.
A. G. Ergul, T. G. Maz, C. Kretzer, A. Olgac, P. M. Jordan, B. Caliskan, O. Werz, E. BanogluNovel potent benzimidazole-based microsomal prostaglandin E-2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C-4 synthaseExterner Link Eur. J. Med. Chem. 2022 , 231 , 13.
W. Foo, A. Wiede, S. Bierwirth, R. Heintzmann, A. T. Press, W. HauswaldAutomated multicolor mesoscopic imaging for the 3-dimensional reconstruction of fluorescent biomarker distribution in large tissue specimensExterner Link Biomed. Opt. Express 2022 , 13 , 3723-3742.
M. Gabel, A. Knauss, D. Fischer, M. F. Neurath, B. WeigmannSurface Design Options in Polymer- and Lipid-Based siRNA Nanoparticles Using AntibodiesExterner Link Int. J. Mol. Sci. 2022 , 23 , 22.
E. Gardey, F. H. Sobotta, S. Quickert, T. Bruns, J. C. Brendel, A. StallmachROS-sensitive polymer micelles for selective degradation in primary human monocytes from patients with active IBDExterner Link Macromol. Biosci. 2022 , 22 , 6.
C. Grune, C. Kretzer, S. Zergiebel, S. Kattner, J. Thamm, S. Hoeppener, O. Werz, D. FischerEncapsulation of the anti-inflammatory dual FLAP/sEH inhibitor diflapolin improves the efficiency in human whole bloodExterner Link J. Pharm. Sci. 2022 , 111 , 1843-1850.
F. Hausig-Punke, F. Richter, M. Hoernke, J. C. Brendel, A. TraegerTracking the endosomal escape: A closer look at calcein and related reportersExterner Link Macromol. Biosci. 2022 , 22 , 26.
T. N. M. Hoang, Z. Cseresnyes, S. Hartung, M. Blickensdorf, C. Saffer, K. Rennert, A. S. Mosig, M. Von Lilienfeld-Toal, M. T. FiggeInvasive aspergillosis-on-chip: A quantitative treatment study of human Aspergillus fumigatus infectionExterner Link Biomaterials 2022 , 283 , 14.
B. Hoffmann, R. Gerst, Z. Cseresnyes, W. Foo, O. Sommerfeld, A. T. Press, M. Bauer, M. T. FiggeSpatial quantification of clinical biomarker pharmacokinetics through deep learning-based segmentation and signal-oriented analysis of MSOT dataExterner Link Photoacoustics 2022 , 26 , 12.
A. Jimenez-Victoria, R. D. Peralta-Rodriguez, E. Saldivar-Guerra, G. Y. Cortez-Mazatan, L. D. A. Soriano-Melgar, C. Guerrero-SanchezEmulsion polymerization using an amphiphilic oligoether ionic liquid as a surfactantExterner Link Polymers 2022 , 14 , 19.
C. Kretzer, P. M. Jordan, R. Bilancia, A. Rossi, T. G. Maz, E. Banoglu, U. S. Schubert, O. WerzShifting the biosynthesis of leukotrienes toward specialized pro-resolving mediators by the 5-lipoxygenase-activating protein (FLAP) antagonist BRP-201Externer Link J. Inflamm. Res. 2022 , 15 , 911-925.
H. Lindemann, T. HeinzeCellulose allylcarbamate with high content of reactive double bonds for thiol-ene reactionExterner Link React. Funct. Polym. 2022 , 176 , 5.
N. Liu, M. Bauer, A. T. PressThe immunological function of CXCR2 in the liver during sepsisExterner Link J. Inflamm. 2022 , 19 , 13.
L. Miek, P. M. Jordan, K. Gunther, S. Pace, T. Beyer, D. Kowalak, V. Hoerr, B. Loffler, L. Tuchscherr, C. N. Serhan, J. Gerstmeier, O. WerzStaphylococcus aureus controls eicosanoid and specialized pro-resolving mediator production via lipoteichoic acidExterner Link Immunology 2022 , 166 , 47-67.
F. L. Portwich, Y. Carstensen, A. Dasgupta, S. Kupfer, R. Wyrwa, H. Gorls, C. Eggeling, B. Dietzek, S. Grafe, M. Wachtler, R. KretschmerA highly fluorescent dinuclear aluminium complex with near-unity quantum yieldExterner Link Angew. Chem. Int. Ed. 2022 , 61 , 5.
M. Potenza, A. Giordano, M. G. Chini, A. Saviano, C. Kretzer, F. Raucci, M. Russo, G. Lauro, S. Terracciano, I. Bruno, M. Iorizzi, R. K. Hofstetter, S. Pace, F. Maione, O. Werz, G. BifulcoIdentification of 2-aminoacyl-1,3,4-thiadiazoles as prostaglandin E-2 and leukotriene biosynthesis inhibitorsExterner Link ACS Med. Chem. Lett. 2022 , 14 , 26-34.
Z. G. Rao, D. Caprioglio, A. Gollowitzer, C. Kretzer, D. Imperio, J. A. Collado, L. Waltl, S. Lackner, G. Appendino, E. Munoz, V. Temml, O. Werz, A. Minassi, A. KoeberleRotational constriction of curcuminoids impacts 5-lipoxygenase and mPGES-1 inhibition and evokes a lipid mediator class switch in macrophagesExterner Link Biochem. Pharmacol. 2022 , 203 , 16.
M. Reichel, V. Weitzel, L. Klement, C. Hoffmann, J. DrubeSuitability of GRK antibodies for individual detection and quantification of GRK isoforms in western blotsExterner Link Int. J. Mol. Sci. 2022 , 23 , 1195.
I. Richter, S. Radosa, Z. Cseresnyes, I. Ferling, H. Buttner, S. P. Niehs, R. Gerst, K. Scherlach, M. T. Figge, F. Hillmann, C. HertweckToxin-producing endosymbionts shield pathogenic fungus against micropredatorsExterner Link mBio 2022 , 13 , 16.
A. Saviano, S. De Vita, M. G. Chini, N. Marigliano, G. Lauro, G. M. Casillo, F. Raucci, M. Iorizzi, R. K. Hofstetter, K. Fischer, A. Koeberle, O. Werz, F. Maione, G. BifulcoIn silico, in vitro and in vivo analysis of tanshinone IIA and cryptotanshinone from salvia miltiorrhiza as modulators of cyclooxygenase-2/mPGES-1/endothelial prostaglandin EP3 pathwayExterner Link Biomolecules 2022 , 12 , 26.
F. Siwczak, Z. Cseresnyes, M. I. A. Hassan, K. O. Aina, S. Carlstedt, A. Sigmund, M. Groger, B. G. J. Surewaard, O. Werz, M. T. Figge, L. Tuchscherr, B. Loffler, A. S. MosigHuman macrophage polarization determines bacterial persistence of Staphylococcus aureus in a liver-on-chip-based infection modelExterner Link Biomaterials 2022 , 287 , 12.
J. I. Solomun, L. Martin, P. Mapfumo, E. Moek, E. Amro, F. Becker, S. Tuempel, S. Hoeppener, K. L. Rudolph, A. TraegerpH-sensitive packaging of cationic particles by an anionic block copolymer shellExterner Link J. Nanobiotechnol. 2022 , 20 , 17.
G. K. Soni, N. Wangoo, C. Cokca, K. Peneva, R. K. SharmaUltrasensitive aptasensor for arsenic detection using quantum dots and guanylated poly(methacrylamide)Externer Link Anal. Chim. Acta 2022 , 1209 , 10.
L. M. Stafast, C. Weber, M. T. Kuchenbrod, S. Hoeppener, M. Behnke, S. Schubert, K. Mehmetaj, A. T. Press, M. Bauer, U. S. SchubertPoly(2-oxazoline) homopolymers and diblock copolymers containing retinoate omega-end groupsExterner Link ACS Appl. Polym. Mater. 2022 , 4 , 3417-3425.
M. M. Suo, M. K. Rommelfanger, Y. L. Chen, E. M. Amro, B. Han, Z. Y. Chen, K. Szafranski, S. R. Chakkarappan, B. O. Boehm, A. L. MacLean, K. L. RudolphAge-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in miceExterner Link Blood 2022 , 139 , 2653-2665.
I. Terzioglu, C. Ventura-Hunter, J. Ulbrich, E. Saldivar-Guerra, U. S. Schubert, C. Guerrero-SanchezAutomated parallel dialysis for purification of polymersExterner Link Polymers 2022 , 14 , 12.
S. Turanli, A. G. Ergul, P. M. Jordan, A. Olgac, B. Caliskan, O. Werz, E. BanogluQuinazoline-4(3H)-one-7-carboxamide derivatives as human soluble epoxide hydrolase inhibitors with developable 5-lipoxygenase activating protein inhibitionExterner Link ACS Omega 2022 , 7 , 36354–36365.
C. Ventura-Hunter, V. D. Lechuga-Islas, J. Ulbrich, C. Kellner, U. S. Schubert, E. Saldivar-Guerra, M. Rosales-Guzman, C. Guerrero-SanchezGlycerol methacrylate-based copolymers: Reactivity ratios, physicochemical characterization and cytotoxicityExterner Link Eur. Polym. J. 2022 , 178 , 111478.
L. Vieider, E. Zoeller, E. Romp, M. Schoenthaler, V. Hernandez-Olmos, V. Temml, T. Hasenoehrl, D. Schuster, O. Werz, U. Garscha, B. MatuszczakSynthesis and structure-activity relationships for some novel diflapolin derivatives with benzimidazole subunitExterner Link J. Enzym. Inhib. Med. Chem. 2022 , 37 , 1752-1764.
M. Wejner, T. WilkeLabPi: A digital measuring station for STEM education 4.0Externer Link J. Chem. Educ. 2022 , 99 , 819-827.
X. B. Yao, C. Hoppener, H. Schneidewind, S. Hoeppener, Z. A. Tang, A. Buchholz, A. Konig, S. Mogavero, M. Diegel, J. Dellith, A. Turchanin, W. Plass, B. Hube, V. DeckertTargeted suppression of peptide degradation in Ag-based surface-enhanced Raman spectra by depletion of hot carriersExterner Link Small 2022 , 18 , 2205080.
K. H. Zhang, P. M. Jordan, S. Pace, R. K. Hofstetter, M. Werner, X. C. Chen, O. WerzModulation of inflammation-related lipid mediator pathways by celastrol during human macrophage polarizationExterner Link J. Inflamm. Res. 2022 , 15 , 3285-3304.
Z. Wallace, J. Kopycinski, H. Yang, M. L. McCully, C. Eggeling, J. Chojnacki, L. Dorrell Immune mobilising T cell receptors redirect polyclonal CD8+ T cells in chronic HIV infection to form immunological synapsesExterner Link Sci. Rep. 2022 , (12), 13.
S. Insausti, M. Garcia-Porras, J. Torralba, I. Morillo, A. Ramos-Caballero, I. de la Arada, B. Apellaniz, J. M. M. Caaveiro, P. Carravilla, C. Eggeling, E. Rujas, J. L. Nieva Functional delineation of a protein–membrane interaction hotspot site on the HIV-1 neutralizing antibody 10E8Externer Link Int. J. Mol. Sci. 2022 , 23 (18), 17.
S. Galiani, K. Reglinski, P. Carravilla, A. Barbotin, I. Urbancic, J. Ott, J. Sehr, E. Sezgin, F. Schneider, D. Waithe, P. Hublitz, W. Schliebs, R. Erdmann, C. Eggeling Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5Externer Link Biophys. Rep . 2022 , (2), 15.
H. Lindemann, T. Heinze, Cellulose allylcarbamate with high content of reactive double bonds for thiol-ene reactionExterner Link React. Funct. Polym . 2022 , 176, 105306.
N. E. Goppert, M. Dirauf, P. Liebing, C. Weber, U. S. SchubertOrganocatalyzed ring-opening polymerization of (S)-3-benzylmorpholine-2,5-dioneExterner Link Macromol. Rapid Commun. 2022 , 44 , 6.
2021
C. Kretzer, B. Shkodra, P. Klemm, P. M. Jordan, D. Schröder, G. Cinar, A. Vollrath, S. Schubert, I. Nischang, S. Hoeppener, S. Stumpf, E. Banoglu, F. Gladigau, R. Bilancia, A. Rossi, C. Eggeling, U. Neugebauer, U. S. Schubert, O. WerzEthoxy acetalated dextran-based nanocarriers accomplish efficient inhibition of leukotriene formation by a novel FLAP antagonist in human leukocytes and bloodExterner Link Cell. Mol. Life Sci. 2021 , 79 , 40.
A. M. Ali, M. Egiza, K. Murasawa, H. Sugita, T. Deckert-Gaudig, V. Deckert, T. YoshitakeEffects of substrate temperature and intermediate layer on adhesion, structural and mechanical properties of coaxial arc plasma deposition grown nanodiamond composite films on Si substratesExterner Link Surf. Coat. Technol. 2021 , 417 , 127185.
T. T. V. Anh, A. Mostafa, Z. G. Rao, S. Pace, S. Schwaiger, C. Kretzer, V. Temml, C. Giesel, P. M. Jordan, R. Bilancia, C. Weinigel, S. Rummler, B. Waltenberger, T. Hung, A. Rossi, H. Stuppner, O. Werz, A. KoeberleFrom Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolutionExterner Link Acta Pharmaceutica Sinica B 2021 , 11 , 1629-1647.
M. Brunzel, M. Dirauf, M. Sahn, J. A. Czaplewska, N. Fritz, C. Weber, I. Nischang, U. S. SchubertOn the identification and quantification of proton-initiated species in the synthesis of poly(2-alkyl-2-oxazoline)s by high resolution liquid chromatographyExterner Link J. Chromatogr. A 2021 , 1653 , 462364.
H. Büttner, S. P. Niehs, K. Vandelannoote, Z. Cseresnyés, B. Dose, I. Richter, R. Gerst, M. T. Figge, T. P. Stinear, S. J. Pidot, C. HertweckBacterial endosymbionts protect beneficial soil fungus from nematode attackExterner Link PNAS 2021 , 118 , e2110669118.
C. Chen, F. Richter, J. L. Zhang, C. Guerrero-Sanchez, A. Traeger, U. S. Schubert, A. C. Feng, S. H. ThangSynthesis of functional miktoarm star polymers in an automated parallel synthesizerExterner Link Eur. Polym. J. 2021 , 160 , 110777.
Y. L. Chen, K. L. RudolphGranulocyte colony-stimulating factor acts on lymphoid-biased, short-term hematopoietic stem cellsExterner Link Haematologica 2021 , 106 , 1516-1518.
C. Cokca, F. J. Hack, D. Costabel, K. Herwig, J. Hulsmann, P. Then, R. Heintzmann, D. Fischer, K. PenevaPEGylation of guanidinium and indole bearing poly(methacrylamide)s - Biocompatible terpolymers for pDNA deliveryExterner Link Macromol. Biosci. 2021 , 21 , 2100146.
E. Y. Darussalam, O. Peterfi, T. Deckert-Gaudig, L. Roussille, V. DeckertpH-dependent disintegration of insulin amyloid fibrils monitored with atomic force microscopy and surface-enhanced Raman spectroscopyExterner Link Spectrochim. Acta A Mol. Biomol. Spect. 2021 , 256 , 119672.
M. A. De Jesus-Tellez, S. De la Rosa-Garcia, I. Medrano-Galindo, I. Rosales-Penafiel, S. Gomez-Cornelio, C. Guerrero-Sanchez, U. S. Schubert, P. Quintana-OwenAntifungal properties of poly 2-(dimethylamino)ethyl methacrylate (PDMAEMA) and quaternized derivativesExterner Link React. Funct. Polym. 2021 , 163 , 104887.
S. Deb, D. A. Felix, P. Koch, M. K. Deb, K. Szafranski, K. Buder, M. Sannai, M. Groth, J. Kirkpatrick, S. Pietsch, A. Gollowitzer, A. Gross, P. Riemenschneider, A. Koeberle, C. Gonzalez-Estevez, K. L. RudolphTnfaip2/exoc3-driven lipid metabolism is essential for stem cell differentiation and organ homeostasisExterner Link EMBO Rep. 2021 , 22 , e49328.
S. Deinhardt-Emmer, S. Bottcher, C. Haring, L. Giebeler, A. Henke, R. Zell, J. Jungwirth, P. M. Jordan, O. Werz, F. Hornung, C. Brandt, M. Marquet, A. S. Mosig, M. W. Pletz, M. Schacke, J. Rodel, R. Heller, S. Nietzsche, B. Loffler, C. EhrhardtSARS-CoV-2 causes severe epithelial inflammation and barrier dysfunctionExterner Link J. Virol. 2021 , 95 , e00110-21.
M. Dirauf, N. Fritz, M. Gottschaldt, C. Weber, U. S. SchubertPoly(2-ethyl-2-oxazoline) featuring a central amino moietyExterner Link Macromol. Rapid Commun. 2021 , 42 , 2100132.
D. Fischer, N. Dusek, K. Hotzel, T. HeinzeThe role of formamidine groups in dextran based nonviral vectors for gene delivery on their physicochemical and biological characteristicsExterner Link Macromol. Biosci. 2021 , 21 , 2000220.
L. Friedrich, G. Cingolani, Y. H. Ko, M. Iaselli, M. Miciaccia, M. G. Perrone, K. Neukirch, V. Bobinger, D. Merk, R. K. Hofstetter, O. Werz, A. Koeberle, A. Scilimati, G. SchneiderLearning from nature: From a marine natural product to synthetic cyclooxygenase-1 inhibitors by automated de novo designExterner Link Adv. Sci. 2021 , 8 , 2100832.
A. N. Garcia-Sanchez, R. Yanez-Macias, J. L. Hernandez-Flores, A. Alvarez-Morales, J. H. Valenzuela-Soto, C. Guerrero-Sanchez, R. Guerrero-SantosExogenous application of polycationic nanobactericide on tomato plants reduces the candidatus liberibacter solanacearum infectionExterner Link Plants 2021 , 10 , 2096.
N. C. Gilbert, M. E. Newcomer, O. WerzUntangling the web of 5-lipoxygenase-derived products from a molecular and structural perspective: The battle between pro- and anti-inflammatory lipid mediatorsExterner Link Biochem. Pharmacol. 2021 , 193 , 114759.
N. E. Göppert, M. Dirauf, C. Weber, U. S. SchubertBlock copolymers comprising degradable poly(2-ethyl-2-oxazoline) analogues via copper-free click chemistryExterner Link Polym. Chem. 2021 , 12 , 5426–5437.
C. Grune, C. Zens, A. Czapka, K. Scheuer, J. Thamm, S. Hoeppener, K. D. Jandt, O. Werz, U. Neugebauer, D. FischerSustainable preparation of anti-inflammatory atorvastatin PLGA nanoparticlesExterner Link Int. J. Pharm. 2021 , 599 , 120404.
F. V. Gruschwitz, T. Klein, M. T. Kuchenbrod, N. Moriyama, S. Fujii, I. Nischang, S. Hoeppener, K. Sakurai, U. S. Schubert, J. C. BrendelKinetically controlling the length of self-assembled polymer nanofibers formed by intermolecular hydrogen bondsExterner Link ACS Macro Lett. 2021 , 10 , 837-843.
T. Gürses, A. Olğaç, U. Garscha, T. Gür Maz, N. B. Bal, O. Uludağ, B. Çalışkan, U. S. Schubert, O. Werz, E. BanogluSimple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacyExterner Link Bioorg. Chem. 2021 , 112 , 104861.
O. Gutierrez-Gutierrez, D. A. Felix, A. Salvetti, E. M. Amro, A. Thems, S. Pietsch, A. Koeberle, K. L. Rudolph, C. Gonzalez-EstevezRegeneration in starved planarians depends on TRiC/CCT subunits modulating the unfolded protein responseExterner Link EMBO Rep. 2021 , 22 , e52905.
S. Hanio, J. Schlauersbach, B. Lenz, F. Spiegel, R. A. Böckmann, R. Schweins, I. Nischang, U. S. Schubert, S. Endres, A.-C. Pöppler, F. P. Brandl, T. M. Smit, K. Kolter, L. MeinelDrug-induced dynamics of bile colloidsExterner Link Langmuir 2021 , 37 , 2543-2551.
M. I. A. Hassan, M. Keller, M. Hillger, U. Binder, S. Reuter, K. Herold, A. Telagathoti, H.-M. Dahse, S. Wicht, N. Trinks, S. Nietzsche, T. Deckert-Gaudig, V. Deckert, R. Mrowka, U. Terpitz, H. Peter Saluz, K. VoigtThe impact of episporic modification of Lichtheimia corymbifera on virulence and interaction with phagocytesExterner Link Comput. Struct. Biotechnol. J. 2021 , 19 , 880-896.
F. Hausig, F. H. Sobotta, F. Richter, D. O. Harz, A. Traeger, J. C. BrendelCorrelation between protonation of tailor-made polypiperazines and endosomal escape for cytosolic protein deliveryExterner Link ACS Appl. Mater. Interfaces 2021 , 13 , 35233-35247.
R. HeintzmannAnswers to fundamental questions in superresolution microscopyExterner Link Philos. Trans. A Math. Phys. Eng. Sci. 2021 , 379.
P. M. Jordan, N. Andreas, M. Groth, P. Wegner, F. Weber, U. Jager, C. Kuchler, O. Werz, E. Serfling, T. Kamradt, A. Dudeck, S. DrubeATP/IL-33-triggered hyperactivation of mast cells results in an amplified production of pro-inflammatory cytokines and eicosanoidsExterner Link Immunology 2021 , 164 , 541-554.
P. M. Jordan, O. WerzSpecialized pro-resolving mediators: Biosynthesis and biological role in bacterial infectionsExterner Link FEBS J. 2021 , DOI: 10.1111/febs.16266
T. Kammann, J. Hoff, I. Yildirim, B. Shkodra, T. Müller, C. Weber, M. H. Gräler, U. A. Maus, J. C. Paton, M. Singer, A. Traeger, U. S. Schubert, M. Bauer, A. T. PressIntracellularly released cholesterol from polymer-based delivery systems alters cellular responses to pneumolysin and promotes cell survivalExterner Link Metabolites 2021 , 11 , 821.
J. Kimmig, T. Schuett, A. Vollrath, S. Zechel, U. S. SchubertPrediction of nanoparticle sizes for arbitrary methacrylates using artificial neuronal networksExterner Link Adv. Sci. 2021 , 8 , 2102429.
J. Kimmig, S. Zechel, U. S. SchubertDigital transformation in materials science: A paradigm change in material's developmentExterner Link Adv. Mater. 2021 , 33 , 2004940.
T. Klein, F. V. Gruschwitz, M. T. Kuchenbrod, I. Nischang, S. Hoeppener, J. C. BrendelAdjusting the length of supramolecular polymer bottlebrushes by top-down approachesExterner Link Beilst. J. Org. Chem. 2021 , 17 , 2621-2628.
T. Klein, H. F. Ulrich, F. V. Gruschwitz, M. T. Kuchenbrod, R. Takahashi, S. Hoeppener, I. Nischang, K. Sakurai, J. C. BrendelOvercoming the necessity of a lateral aggregation in the formation of supramolecular polymer bottlebrushes in waterExterner Link Macromol. Rapid Commun. 2021 , 42 , 2000585.
P. Klemm, M. Behnke, J. I. Solomun, C. Bonduelle, S. Lecommandoux, A. Traeger, S. SchubertSelf-assembled PEGylated amphiphilic polypeptides for gene transfectionExterner Link J. Mater. Chem. B 2021 , 9 , 8149-8356.
S. Kluge, M. Schubert, L. Bormel, S. LorkowskiThe vitamin E long-chain metabolite alpha-13 '-COOH affects macrophage foam cell formation via modulation of the lipoprotein lipase systemExterner Link Biochim. Biophys. Acta - Mol. Cell Biol. Lipids 2021 , 1866 , 158875.
M. Kohler, P. Rinke, K. Fiederling, H. Gorls, N. Ueberschaar, F. H. Schacher, R. KretschmerCatalytic activity of various beta-diketiminate zinc complexes toward the ring-opening polymerization of caprolactone and derivativesExterner Link Macromol. Chem. Phys. 2021 , 222 , 2100187.
B. Kokot, H. Kokot, P. Umek, K. P. van Midden, S. Pajk, M. Garvas, C. Eggeling, T. Koklic, I. Urbancic, J. StrancarHow to control fluorescent labeling of metal oxide nanoparticles for artefact-free live cell microscopyExterner Link Nanotoxicology 2021 , 15 , 1102-1123.
M. Kuhne, C. Kretzer, H. Lindemann, M. Godmann, T. Heinze, O. Werz, T. HeinzelBiocompatible valproic acid-coupled nanoparticles attenuate lipopolysaccharide-induced inflammationExterner Link Int. J. Pharm. 2021 , 601 , 120567.
M. Kuhne, H. Lindemann, C. Grune, D. Schroder, Z. Cseresnyes, M. Godmann, A. Koschella, M. T. Figge, C. Eggeling, D. Fischer, T. Heinze, T. HeinzelBiocompatible sulfated valproic acid-coupled polysaccharide-based nanocarriers with HDAC inhibitory activityExterner Link J. Control. Release 2021 , 329 , 717-730.
V. D. Lechuga-Islas, M. Trejo-Maldonado, S. Stumpf, R. Guerrero-Santos, L. Elizalde-Herrera, U. S. Schubert, C. Guerrero-SanchezSeparation of volatile compounds from polymers by physisorptionExterner Link Eur. Polym. J. 2021 , 159 , 110748.
K. Leer, G. Cinar, J. I. Solomun, L. Martin, I. Nischang, A. TraegerCore-crosslinked, temperature- and pH-responsive micelles: design, physicochemical characterization, and gene delivery applicationExterner Link Nanoscale 2021 , 13 , 19412-19429.
B. Loffler, L. TuchscherrStaphylococcus aureus toxins: Promoter or handicap during infection?Externer Link Toxins 2021 , 13 , 287.
I. Muljajew, M. Chi, A. Vollrath, C. Weber, B. Beringer-Siemers, S. Stumpf, S. Hoeppener, M. Sierka, U. S. SchubertA combined experimental and in silico approach to determine the compatibility of poly(ester amide)s and indomethacin in polymer nanoparticlesExterner Link Eur. Polym. J. 2021 , 156 , 110606.
I. Muljajew, S. Huschke, A. Ramoji, Z. Cseresnyés, S. Hoeppener, I. Nischang, W. Foo, J. Popp, M. T. Figge, C. Weber, M. Bauer, U. S. Schubert, A. T. PressStealth effect of short polyoxazolines in graft copolymers: Minor changes of backbone end group determine liver cell-type specificityExterner Link ACS Nano 2021 , 15 , 12298–12313
K. Neukirch, K. Alsabil, C. P. Dinh, R. Bilancia, M. Raasch, A. Ville, I. Cerqua, G. Viault, D. Breard, S. Pace, V. Temml, E. Brunner, P. M. Jordan, M. C. Marques, K. Loeser, A. Gollowitzer, S. Permann, J. Gerstmeier, S. Lorkowski, H. Stuppner, U. Garscha, T. Rodrigues, G. J. L. Bernardes, D. Schuster, D. Seraphin, P. Richomme, A. Rossi, A. S. Mosig, F. Roviezzo, O. Werz, J. J. Helesbeux, A. KoeberleExploration of long-chain vitamin E metabolites for the discovery of a highly potent, orally effective, and metabolically stable 5-LOX Inhibitor that limits inflammationExterner Link J. Med. Chem. 2021 , 64 , 11496-11526.
M. F. Osuchowski, M. S. Winkler, T. Skirecki, S. Cajander, M. Shankar-Hari, G. Lachmann, G. Monneret, F. Venet, M. Bauer, F. M. Brunkhorst, S. Weis, A. Garcia-Salido, M. Kox, J.-M. Cavaillon, F. Uhle, M. A. Weigand, S. B. Flohé, W. J. Wiersinga, R. Almansa, A. de la Fuente, I. Martin-Loeches, C. Meisel, T. Spinetti, J. C. Schefold, C. Cilloniz, A. Torres, E. J. Giamarellos-Bourboulis, R. Ferrer, M. Girardis, A. Cossarizza, M. G. Netea, T. van der Poll, J. F. Bermejo-Martín, I. RubioThe COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entityExterner Link The Lancet Respiratory Medicine 2021 , 9 , 622-642.
S. Pace, K. Zhang, P. M. Jordan, R. Bilancia, W. Wang, F. Börner, R. K. Hofstetter, M. Potenza, C. Kretzer, J. Gerstmeier, D. Fischer, S. Lorkowski, N. C. Gilbert, M. E. Newcomer, A. Rossi, X. Chen, O. WerzAnti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediatorsExterner Link Pharmacol. Res. 2021 , 167 , 105556.
H. Penkert, A. Bertrand, V. Tiwari, S. Breimann, S. A. Muller, P. M. Jordan, M. J. Gerl, C. Klose, L. Cantuti-Castelvetri, M. Bosch-Queralt, I. Levental, S. F. Lichtenthaler, O. Werz, M. SimonsProteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recoveryExterner Link Cell Reports 2021 , 37, 109898.
M. Potenza, M. Sciarretta, M. G. Chini, A. Saviano, F. Maione, M. V. D'Auria, S. De Marino, A. Giordano, R. K. Hofstetter, C. Festa, O. Werz, G. BifulcoStructure-based screening for the discovery of 1,2,4-oxadiazoles as promising hits for the development of new anti-inflammatory agents interfering with eicosanoid biosynthesis pathwaysExterner Link Eur. J. Med. Chem. 2021 , 224 , 113693.
A. T. Press, P. Babic, B. Hoffmann, T. Müller, W. Foo, W. Hauswald, J. Benecke, M. Beretta, Z. Cseresnyés, S. Hoeppener, I. Nischang, S. M. Coldewey, M. H. Gräler, R. Bauer, F. Gonnert, N. Gaßler, R. Wetzker, M. T. Figge, U. S. Schubert, M. BauerTargeted delivery of a phosphoinositide 3-kinase γ inhibitor to restore organ function in sepsisExterner Link EMBO Mol. Med. 2021 , 13 , e14436.
L. Pusch, R. Brox, K. Scheuer, T. Yokosawa, M. Wu, B. A. Zubiri, E. Spiecker, K. D. Jandt, D. Fischer, H. HacksteinDistinct endocytosis and immune activation of poly(lactic-co-glycolic) acid nanoparticles prepared by single- and double-emulsion evaporationExterner Link Nanomedicine 2021 , 16 , 2075-2094.
F. Richter, K. Leer, L. Martin, P. Mapfumo, J. I. Solomun, M. T. Kuchenbrod, S. Hoeppener, J. C. Brendel, A. TraegerThe impact of anionic polymers on gene delivery: how composition and assembly help evading the toxicity-efficiency dilemmaExterner Link J. Nanobiotechnol. 2021 , 19 , 292.
F. Richter, P. Mapfumo, L. Martin, J. I. Solomun, F. Hausig, J. J. Frietsch, T. Ernst, S. Hoeppener, J. C. Brendel, A. TraegerImproved gene delivery to K-562 leukemia cells by lipoic acid modified block copolymer micellesExterner Link J. Nanobiotechnol. 2021 , 19 , 70.
T. Ritschel, K. Lehmann, M. Brunzel, J. Vitz, I. Nischang, U. S. Schubert, K. U. TotscheWell-defined poly(ethylene glycol) polymers as non-conventional reactive tracers of colloidal transport in porous mediaExterner Link J. Colloid Interface Sci. 2021 , 584 , 592-601.
M. Rodewald, H. Bae, S. Huschke, T. Meyer-Zedler, M. Schmitt, A. T. Press, S. Schubert, M. Bauer, J. PoppIn vivo coherent anti-Stokes Raman scattering microscopy reveals vitamin A distribution in the liverExterner Link J. Biophotonics 2021 , 14 , e202100040.
E. Rujas, D. P. Leaman, S. Insausti, P. Carravilla, M. Garcia-Porras, E. Largo, I. Morillo, R. Sanchez-Eugenia, L. Zhang, H. Cui, I. Iloro, F. Elortza, J. P. Julien, C. Eggeling, M. B. Zwick, J. M. M. Caaveiro, J. L. NievaFocal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profileExterner Link Iscience 2021 , 24 , 102987.
P. Schädel, F. Troisi, A. Czapka, N. Gebert, S. Pace, A. Ori, O. WerzAging drives organ-specific alterations of the inflammatory microenvironment guided by immunomodulatory mediators in miceExterner Link The FASEB Journal 2021 , 35 , e21558.
F. Schneider, T. Sych, C. Eggeling, E. SezginInfluence of nanobody binding on fluorescence emission, mobility, and organization of GFP-tagged proteinsExterner Link Iscience 2021 , 24 , 101891.
M. Sittig, J. C. Tom, J. K. Elter, F. H. Schacher, B. DietzekQuinoline photobasicity: Investigation within water-soluble light-responsive copolymersExterner Link Chem. Eur. J. 2021 , 27 , 1072-1079.
F. H. Sobotta, M. T. Kuchenbrod, C. Grune, D. Fischer, S. Hoeppener, J. C. BrendelElucidating preparation-structure relationships for the morphology evolution during the RAFT dispersion polymerization of N-acryloyl thiomorpholineExterner Link Polym. Chem. 2021 , 12 , 1668-1680.
F. H. Sobotta, M. T. Kuchenbrod, F. V. Gruschwitz, G. Festag, P. Bellstedt, S. Hoeppener, J. C. BrendelTuneable time delay in the burst release from oxidation-sensitive polymersomes made by PISAExterner Link Angew. Chem. Int. Ed. 2021 , 60 , 24716-24723.
O. Sommerfeld, A. Medyukhina, S. Neugebauer, M. Ghait, S. Ulferts, A. Lupp, R. König, R. Wetzker, S. Schulz, M. T. Figge, M. Bauer, A. T. PressTargeting complement C5a receptor 1 for the treatment of immunosuppression in sepsisExterner Link Mol. Ther. 2021 , 29 , 338-346.
F. A. Stanford, N. Matthies, Z. Cseresnyés, M. T. Figge, M. I. A. Hassan, K. VoigtExpression patterns in reductive iron assimilation and functional consequences during phagocytosis of Lichtheimia corymbifera, an emerging cause of mucormycosisExterner Link Journal of Fungi 2021 , 7 , 272.
B. H. Stumpf, P. Nowakowski, C. Eggeling, A. Maciolek, A. S. SmithProtein induced lipid demixing in homogeneous membranesExterner Link Phys. Rev. Res. 2021 , 3 , L042013.
A. Tannert, J. G. Lopez, N. Petkov, A. Ivanova, K. Peneva, U. NeugebauerLysosome-targeting pH indicator based on peri-fused naphthalene monoimide with superior stability for long term live cell imagingExterner Link J. Mater. Chem. B 2021 , 9 , 112-124.
I. Urbancic, L. Schiffelers, E. Jenkins, W. J. Gong, A. M. Santos, F. Schneider, C. O'Brien-Ball, M. T. Vuong, N. Ashman, E. Sezgin, C. EggelingAggregation and mobility of membrane proteins interplay with local lipid order in the plasma membrane of T cellsExterner Link FEBS Lett. 2021 , 595 , 2127-2146.
A. Vollrath, C. Kretzer, B. Beringer-Siemers, B. Shkodra, J. A. Czaplewska, D. Bandelli, S. Stumpf, S. Hoeppener, C. Weber, O. Werz, U. S. SchubertEffect of crystallinity on the properties of polycaprolactone nanoparticles containing the dual FLAP/mPEGS-1 inhibitor BRP-187Externer Link Polymers 2021 , 13 , 2557.
L. Wang, U. S. Schubert, S. HoeppenerSurface chemical reactions on self-assembled silane based monolayersExterner Link Chem. Soc. Rev. 2021 , 50 , 6507-6540.
L. Wang, A. A. Womiloju, C. Höppener, U. S. Schubert, S. HoeppenerOn the stability of microwave-fabricated SERS substrates – chemical and morphological considerationsExterner Link Beilst. J. Nanotechnol. 2021 , 12 , 541-551.
S. Willems, L. Gellrich, A. Chaikuad, S. Kluge, O. Werz, J. Heering, S. Knapp, S. Lorkowski, M. Schubert-Zsilavecz, D. MerkEndogenous vitamin E metabolites mediate allosteric PPARγ activation with unprecedented co-regulatory interactionsExterner Link Cell Chem. Biol. 2021 , 28 , 1489-1500.
K. Zhang, S. Pace, P. M. Jordan, L. K. Peltner, A. Weber, D. Fischer, R. K. Hofstetter, X. Chen, O. WerzBeneficial modulation of lipid mediator biosynthesis in innate immune cells by antirheumatic tripterygium wilfordii glycosidesExterner Link Biomolecules 2021 , 11 , 746.
J. Alex, J. Ulbrich, M. Rosales-Guzmán, C. Weber, U. S. Schubert, C. Guerrero-SanchezKinetic investigations on homo- and co-polymerizations of pentafluorophenyl (meth)acrylatesExterner Link Eur. Polym. J. 2021 , 143 , 110175.
F. Becker, K. L. RudolphTargeting enzyme agingExterner Link Science 2021 , DOI: 10.1126/science.abf9566.
C. Grune, J. Thamm, O. Werz, D. FischerCyrene™ as an alternative sustainable solvent for the preparation of poly(lactic-co-glycolic acid) nanoparticlesExterner Link J. Pharm. Sci. 2021 , 110 , 959-964.
P. Klemm, S. Huschke, M. Rodewald, N. Ehteshamzad, M. Behnke, X. Wang, G. Cinar, I. Nischang, S. Hoeppener, C. Weber, A. Press, C. Höppener, T. Meyer, V. K. Deckert, M. Schmitt, J. Popp, M. Bauer, S. SchubertCharacterization of a library of vitamin A-functionalized polymethacrylate-based nanoparticles for siRNA deliveryExterner Link Polym. Chem. 2021 , DOI: 10.1039/D1030PY01626H.
K. L. RudolphStem cell agingExterner Link Mech. Ageing Dev. 2021 , 193 , 111394.
J. I. Solomun, G. Cinar, P. Mapfumo, F. Richter, E. Moek, F. Hausig, L. Martin, S. Hoeppener, I. Nischang, A. TraegerSolely aqueous formulation of hydrophobic cationic polymers for efficient gene deliveryExterner Link Int. J. Pharm. 2021 , 593 , 120080.
C. St Thomas, L. E. Elizalde, E. J. Regalado, M. A. De Jesús-Téllez, G. Festag, U. S. Schubert, C. Guerrero-SánchezUnderstanding the influence of chemical structure and length of hydrophobic blocks on the rheological properties of associative copolymersExterner Link Eur. Polym. J. 2021 , 143 , 110190.
H. Wang, R. Heintzmann, B. Diederich The power in your pocket – uncover smartphones for use as cutting-edge microscopic instruments in science and researchExterner Link Adv. Opt. Techn . 2021 , 10 (2), 89-108.
C. Guerrero-Sanchez, R. Yañez-Macias, M. Rosales-Guzmán, M. A. De Jesus-Tellez, C. Piñon-Balderrama, J. J. Haven, G. Moad, T. Junkers, U. S. Schubert High-throughput/high-output experimentation in RAFT POLYMER synthesisExterner Link In RAFT Polymerization , 2021 ; pp 1051-1076.
P. Carravilla, A. Dasgupta, G. Zhurgenbayeva, D. I. Danylchuk, A. S. Klymchenko, E. Sezgin, C. EggelingLong-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyesExterner Link Biophys. Rep . 2021 , 1 (2), 100023
2020
M. Behnke, A. Vollrath, L. Klepsch, B. Beringer-Siemers, S. Stumpf, J. A. A. Czaplewska, S. Hoeppener, O. Werz, U. S. SchubertOptimized encapsulation of the FLAP/PGES-1 Inhibitor BRP-187 in PVA-stabilized PLGA nanoparticles using microfluidicsExterner Link Polymers 2020 , 12 , 2751.
S. Deb, D. A. Felix, P. Koch, M. K. Deb, K. Szafranski, K. Buder, M. Sannai, M. Groth, J. Kirkpatrick, S. Pietsch, A. Gollowitzer, A. Groß, P. Riemenschneider, A. Koeberle, C. Gonzalez-Estevez, K. L. RudolphTnfaip2/Exoc3-driven lipid metabolism is essential for stem cell differentiation and organ homeostasisExterner Link EMBO Rep. 2020 , DOI: 10.15252/embr.201949328.
B. Diederich, R. Lachmann, S. Carlstedt, B. Marsikova, H. Wang, X. Uwurukundo, A. Mosig, R. HeintzmannA versatile and customizable low-cost 3D-printed open standard for microscopic imagingExterner Link Nat. Commun. 2020 , DOI: 10.1038/s41467-41020-19447-41469.
B. Farias-Mancilla, J. Zhang, I. Kulai, M. Destarac, U. S. Schubert, C. Guerrero Sanchez, S. Harrisson, O. ColombaniGradient and asymmetric copolymers: The role of the copolymer composition profile in the ionization of weak polyelectrolytesExterner Link Polym. Chem. 2020 , DOI: 10.1039/d1030py01059f.
N. E. Goeppert, M. Kleinsteuber, C. Weber, U. S. SchubertDegradable poly(2-oxazoline) analogues from partially oxidized poly(ethylene imine)Externer Link Macromolecules 2020 , 53 , 10837-10846.
F. J. Hack, C. Cokca, S. Städter, J. Hülsmann, K. Peneva, D. FischerIndole, phenyl and phenol groups - the role of the comonomer on gene delivery in guanidinium containing methacrylamide terpolymersExterner Link Macromol. Rapid Commun. 2020 , 2000580.
C. Helbing, K. D. Jandt Novel protein and peptide nanofibrous structures via supramolecular co-assemblyExterner Link in Artificial Protein and Peptide Nanofibers (Eds.: G. Wei, S. G. Kumbar), Woodhead Publishing, 2020 , pp. 69-97.
T. Klein, H. F. Ulrich, F. V. Gruschwitz, M. T. Kuchenbrod, R. Takahashi, S. Fujii, S. Hoeppener, I. Nischang, K. Sakurai, J. C. BrendelImpact of amino acids on the aqueous self-assembly of benzenetrispeptides into supramolecular polymer bottlebrushesExterner Link Polym. Chem. 2020 , 11 , 6763-6771.
T. Klein, H. F. Ulrich, F. V. Gruschwitz, M. T. Kuchenbrod, R. Takahashi, S. Hoeppener, I. Nischang, K. Sakurai, J. C. BrendelOvercoming the necessity of a lateral aggregation in the formation of supramolecular polymer bottlebrushes in waterExterner Link Macromol. Rapid Commun. 2020, DOI: 10.1002/marc.202000585.
M. T. Kuchenbrod, R. Heintzmann, U. S. Schubert, S. HoeppenerRevisiting staining of biological samples for electron microscopy: Perspectives for recent researchExterner Link Mater. Horiz. 2020 , DOI: 10.1039/D1030MH01579B.
J. J. Lühr, N. Alex, L. Amon, M. Kräter, M. Kubánková, E. Sezgin, C. H. K. Lehmann, L. Heger, G. F. Heidkamp, A.-S. Smith, V. Zaburdaev, R. A. Böckmann, I. Levental, M. L. Dustin, C. Eggeling, J. Guck, D. DudziakMaturation of monocyte-derived DCs leads to increased cellular stiffness, higher membrane fluidity, and changed lipid compositionExterner Link Front. Immunol. 2020 , 11 , 590121.
B. Shkodra, A. T. Press, A. Vollrath, I. Nischang, S. Schubert, S. Hoeppener, D. Haas, C. Enzensperger, M. Lehmann, P. Babic, K. J. Benecke, A. Traeger, M. Bauer, U. S. SchubertFormulation of liver-specific PLGA-DY-635 nanoparticles loaded with the protein kinase C inhibitor bisindolylmaleimide IExterner Link Pharmaceutics 2020 , 12 , 1110.
F. H. Sobotta, M. Kuchenbrod, S. Hoeppener, J. C. BrendelOne polymer composition, various morphologies: the decisive influence of conditions on the polymerization-induced self-assembly (PISA) of N-acryloyl thiomorpholineExterner Link Nanoscale 2020 , 12 , 20171-20176.
A. Tannert, J. Garcia Lopez, N. Petkov, A. Ivanova, K. Peneva, U. NeugebauerLysosome-targeting pH indicator based on peri-fused naphthalene monoimide with superior stability for long term live cell imagingExterner Link J. Mater. Chem. B 2020 , DOI: 10.1039/D1030TB02208J.
M. A. Ali, M. Egiza, K. Murasawa, H. Sugita, T. Deckert-gaudig, V. Deckert, T. YoshitakeInfluence of adhesion intermediate layers on the stability of nanodiamond composite films deposited on Si substrates by coaxial arc plasmaExterner Link Appl. Phys. Exp. 2020 , DOI: 10.35848/31882-30786/ab35891d35841.
A. J. Beer, D. Hertz, E. Seemann, M. Beretta, M. Westermann, R. Bauer, M. Bauer, M. M. Kessels, B. QualmannReduced Mrp2 surface availability as PI3Kγ-mediated hepatocytic dysfunction reflecting a hallmark of cholestasis in sepsisExterner Link Sci. Rep. 2020 , 10 , 13110.
S. Czich, T. Wloka, H. Rothe, J. Rost, F. Penzold, M. Kleinsteuber, M. Gottschaldt, U. S. Schubert, K. LiefeithTwo-photon polymerized poly(2-ethyl-2-oxazoline) hydrogel 3D microstructures with tunable mechanical properties for tissue engineeringExterner Link Molecules 2020 , 25 , 5066.
A. Dorosz, M. Grosicki, J. Dybas, E. Matuszyk, M. Rodewald, T. Meyer, J. Popp, K. Malek, M. BaranskaEosinophils and neutrophils—Molecular differences revealed by spontaneous Raman, CARS and fluorescence microscopyExterner Link Cells 2020 , 9 , 2041.
D. Fischer, N. Dusek, K. Hotzel, T. HeinzeThe role of formamidine groups in dextran based nonviral vectors for gene delivery on their physicochemical and biological characteristicsExterner Link Macromol. Biosci. 2020 , 2000220.
A. T. Frawley, V. Wycisk, Y. Xiong, S. Galiani, E. Sezgin, I. Urbančič, A. Vargas Jentzsch, K. G. Leslie, C. Eggeling, H. L. AndersonSuper-resolution RESOLFT microscopy of lipid bilayers using a fluorophore-switch dyadExterner Link Chem. Sci. 2020 , 11 , 8955-8960.
N. Gebert, C.-W. Cheng, J. M. Kirkpatrick, D. Di Fraia, J. Yun, P. Schädel, S. Pace, G. B. Garside, O. Werz, K. L. Rudolph, H. Jasper, Ö. H. Yilmaz, A. OriRegion-specific proteome changes of the intestinal epithelium during aging and dietary restrictionExterner Link Cell Rep. 2020 , 31 , 107565.
N. C. Gilbert, J. Gerstmeier, E. E. Schexnaydre, F. Börner, U. Garscha, D. B. Neau, O. Werz, M. E. NewcomerStructural and mechanistic insights into 5-lipoxygenase inhibition by natural productsExterner Link Nat. Chem. Biol. 2020 , 16 , 783-790.
F. V. Gruschwitz, M.-C. Fu, T. Klein, R. Takahashi, T. Higashihara, S. Hoeppener, I. Nischang, K. Sakurai, J. C. BrendelUnraveling decisive structural parameters for the self-assembly of supramolecular polymer bottlebrushes based on benzene trisureasExterner Link Macromolecules 2020 , 53 , 7552-7560.
F. V. Gruschwitz, T. Klein, S. Catrouillet, J. C. BrendelSupramolecular polymer bottlebrushesExterner Link Chem. Commun. 2020 , 56 , 5079-5110.
D. Gutowska-Owsiak, E. I. Podobas, C. Eggeling, G. S. Ogg, J. Bernardino de la SernaAddressing differentiation in live human keratinocytes by assessment of membrane packing orderExterner Link Front. Cell Dev. Biol. 2020 , 8 , 573230.
P. Hummel, A. M. Lechner, K. Herrmann, P. Biehl, C. Rössel, L. Wiedenhöft, F. H. Schacher, M. RetschThermal transport in ampholytic polymers: The role of hydrogen bonding and water uptakeExterner Link Macromolecules 2020 , 53 , 5528-5537.
K. D. Jandt, D. C. WattsNanotechnology in dentistry: Present and future perspectives on dental nanomaterialsExterner Link Dent. Mater. 2020 , 36 , 1365-1378.
Y. Li, J. C. Tom, P. Biehl, J. Ling, F. H. SchacherBlock polypeptoids: Synthesis, characterization, and response toward irradiation with UV light and temperatureExterner Link Macromolecules 2020 , 53 , 5218-5226.
J. B. Max, K. Kowalczuk, M. Köhler, C. Neumann, F. Pielenz, L. V. Sigolaeva, D. V. Pergushov, A. Turchanin, F. Langenhorst, F. H. SchacherPolyampholytic poly(dehydroalanine) graft copolymers as smart templates for pH-controlled formation of alloy nanoparticlesExterner Link Macromolecules 2020 , 53 , 4511-4523.
K. Reglinski, L. Steinfort-Effelsberg, E. Sezgin, C. Klose, H. W. Platta, W. Girzalsky, C. Eggeling, R. ErdmannFluidity and lipid composition of membranes of peroxisomes, mitochondria and the ER from oleic acid-induced Saccharomyces cerevisiaeExterner Link Front. Cell Dev. Biol. 2020 , 8 , 574363.
E. Rujas, S. Insausti, D. P. Leaman, P. Carravilla, S. González-Resines, V. Monceaux, R. Sánchez-Eugenia, M. García-Porras, I. Iloro, L. Zhang, F. Elortza, J.-P. Julien, A. Saéz-Cirión, M. B. Zwick, C. Eggeling, A. Ojida, C. Domene, J. M. M. Caaveiro, J. L. NievaAffinity for the Interface Underpins Potency of Antibodies Operating In Membrane EnvironmentsExterner Link Cell Rep. 2020 , 32 , 108037.
E. Schicke, Z. Cseresnyés, K. Rennert, V. Vau, K. F. Haupt, F. Hornung, S. Nietzsche, F. Swiczak, M. Schmidtke, B. Glück, M. Koch, M. Schacke, R. Heller, A. S. Mosig, M. T. Figge, C. Ehrhardt, B. Löffler, S. Deinhardt-EmmerStaphylococcus aureus lung infection results in down-regulation of surfactant protein-A mainly caused by pro-inflammatory macrophagesExterner Link Microorganisms 2020 , 8 , 577.
C. N. Serhan, S. K. Gupta, M. Perretti, C. Godson, E. Brennan, Y. Li, O. Soehnlein, T. Shimizu, O. Werz, V. Chiurchiù, A. Azzi, M. Dubourdeau, S. S. Gupta, P. Schopohl, M. Hoch, D. Gjorgevikj, F. M. Khan, D. Brauer, A. Tripathi, K. Cesnulevicius, D. Lescheid, M. Schultz, E. Särndahl, D. Repsilber, R. Kruse, A. Sala, J. Z. Haeggström, B. D. Levy, J. G. Filep, O. WolkenhauerThe atlas of inflammation resolution (AIR)Externer Link Mol. Asp. Med. 2020 , 74 , 100894.
L. V. Sigolaeva, T. V. Bulko, A. Y. Konyakhina, A. V. Kuzikov, R. A. Masamrekh, J. B. Max, M. Köhler, F. H. Schacher, D. V. Pergushov, V. V. ShumyantsevaRational design of amphiphilic diblock copolymer/MWCNT surface modifiers and their application for direct electrochemical sensing of DNAExterner Link Polymers 2020 , 12 , 1514.
O. Sommerfeld, A. Medyukhina, S. Neugebauer, M. Ghait, S. Ulferts, A. Lupp, R. König, R. Wetzker, S. Schulz, M. T. Figge, M. Bauer, A. T. PressTargeting complement C5a Receptor 1 for the treatment of immunosuppression in sepsisExterner Link Mol. Ther. 2020 , DOI: 10.1016/j.ymthe.2020.1009.1008.
R. Takahashi, S. Miwa, C. Rössel, S. Fujii, J. H. Lee, F. H. Schacher, K. SakuraiPolymersome formation induced by encapsulation of water-insoluble molecules within ABC triblock terpolymersExterner Link Polym. Chem. 2020 , 11 , 3446-3452.
J. Torralba, I. de la Arada, P. Carravilla, S. Insausti, E. Rujas, E. Largo, C. Eggeling, J. L. R. Arrondo, B. Apellániz, J. L. NievaCholesterol constrains the antigenic configuration of the membrane-proximal neutralizing HIV-1 epitopeExterner Link ACS Infect. Dis. 2020 , 6 , 2155-2168.
D. Waithe, J. M. Brown, K. Reglinski, I. Diez-Sevilla, D. Roberts, C. EggelingObject detection networks and augmented reality for cellular detection in fluorescence microscopyExterner Link J. Cell Biol. 2020 , 219 , e201903166.
M. Wallert, L. Börmel, S. LorkowskiInflammatory diseases and vitamin E—What do we know and where do we go?Externer Link Mol. Nutr. Food Res. 2020 , 2000097.
N. Arend, A. Pittner, A. Ramoji, A. S. Mondol, M. Dahms, J. Rüger, O. Kurzai, I. W. Schie, M. Bauer, J. Popp, U. NeugebauerDetection and differentiation of bacterial and fungal infection of neutrophils from peripheral blood using raman spectroscopyExterner Link Anal. Chem. 2020 , 92 , 10560-10568.
G. Cinar, C. Englert, U. S. Schubert, I. NischangSalient features of medical nanoparticles in biological fluids from an analytical ultracentrifugeExterner Link Nanoscale 2020 , DOI: 10.1039/D1030NR06153K.
A. Czapka, S. König, C. Pergola, C. Grune, K. Vougogiannopoulou, A.-L. Skaltsounis, D. Fischer, O. WerzThe indirubin derivative 6-bromoindirubin-3’-glycerol-oxime ether (6BIGOE) potently modulates inflammatory cytokine and prostaglandin release from human monocytes through GSK-3 interferenceExterner Link Biochem. Pharmacol. 2020 , 180 , 114170.
C. P. Dinh, A. Ville, K. Neukirch, G. Viault, V. Temml, A. Koeberle, O. Werz, D. Schuster, H. Stuppner, P. Richomme, J.-J. Helesbeux, D. SéraphinStructure-based design, semi-synthesis and anti-inflammatory activity of tocotrienolic amides as 5-lipoxygenase inhibitorsExterner Link Eur. J. Med. Chem. 2020 , 202 , 112518.
P. Ernst, A. T. Press, M. Fischer, V. Günther, C. Gräfe, J. H. Clement, T. Ernst, U. S. Schubert, J. Wotschadlo, M. Lehmann, C. Enzensperger, M. Bauer, A. HochhausPolymethine dye-functionalized nanoparticles for targeting CML stem cellsExterner Link Mol. Ther. Oncolytics 2020 , 18 , 372-381.
T. Götz, M. Dahms, J. Kirchhoff, C. Beleites, U. Glaser, J. A. Bohnert, M. W. Pletz, J. Popp, P. Schlattmann, U. NeugebauerAutomated and rapid identification of multidrug resistant Escherichia coli against the lead drugs of acylureidopenicillins, cephalosporins, and fluoroquinolones using specific Raman marker bandsExterner Link J. Biophotonics 2020 , 13 , e202000149.
M. Grube, V. Dinu, H. Lindemann, F. Pielenz, G. Festag, U. S. Schubert, T. Heinze, S. Harding, I. NischangPolysaccharide valproates: Structure - property relationships in solutionExterner Link Carbohydr. Polym. 2020 , 246 , 116652.
E. Jäger, S. Murthy, C. Schmidt, M. Hahn, S. Strobel, A. Peters, C. Stäubert, P. Sungur, T. Venus, M. Geisler, V. Radusheva, S. Raps, K. Rothe, R. Scholz, S. Jung, S. Wagner, M. Pierer, O. Seifert, W. Chang, I. Estrela-Lopis, N. Raulien, K. Krohn, N. Sträter, S. Hoeppener, T. Schöneberg, M. Rossol, U. WagnerCalcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritisExterner Link Nat. Commun. 2020 , 11 , 4243.
P. M. Jordan, J. Gerstmeier, S. Pace, R. Bilancia, Z. Rao, F. Börner, L. Miek, Ó. Gutiérrez-Gutiérrez, V. Arakandy, A. Rossi, A. Ialenti, C. González-Estévez, B. Löffler, L. Tuchscherr, C. N. Serhan, O. WerzStaphylococcus aureus-derived α-hemolysin evokes generation of specialized pro-resolving mediators promoting inflammation resolutionExterner Link Cell Reports 2020 , 33 , 108247.
M. Kühne, H. Lindemann, C. Grune, D. Schröder, Z. Cseresnyés, M. Godmann, A. Koschella, M. T. Figge, C. Eggeling, D. Fischer, T. Heinze, T. HeinzelBiocompatible sulfated valproic acid-coupled polysaccharide-based nanocarriers with HDAC inhibitory activityExterner Link J. Control. Release 2020 , DOI: 10.1016/j.jconrel.2020.1010.1006.
A. Lezov, A. Gubarev, T. Kaiser, W. Tobaschus, N. Tsvetkov, I. Nischang, U. S. Schubert, H. Frey, I. Perevyazko“Hard” sphere behavior of “soft”, globular-like, hyperbranched polyglycerols – Extensive molecular hydrodynamic and light scattering studiesExterner Link Macromolecules 2020 , DOI: 10.1021/acs.macromol.1020c01340.
S. Pace, O. WerzImpact of androgens on inflammation-related lipid mediator biosynthesis in innate immune cellsExterner Link Front. Immunol. 2020 , 11 , DOI: 10.3389/fimmu.2020.01356.
S. Rahimi, S. Stumpf, O. Grimm, F. H. Schacher, U. S. Schubert, S. SchubertDual photo- and pH-responsive spirooxazine-functionalized dextran nanoparticlesExterner Link Biomacromolecules 2020 , 21 , 3620-3630.
T. Ritschel, K. Lehmann, M. Brunzel, J. Vitz, I. Nischang, U. S. Schubert, K. U. TotscheWell-defined poly(ethylene glycol) polymers as non-conventional reactive tracers of colloidal transport in porous mediaExterner Link J. Colloid Interface Sci. 2020 , DOI: 10.1016/j.jcis.2020.1009.1056.
K. Scheuer, D. Bandelli, C. Helbing, C. Weber, J. Alex, J. B. Max, A. Hocken, O. Stranik, L. Seiler, F. Gladigau, U. Neugebauer, F. H. Schacher, U. S. Schubert, K. D. JandtSelf-assembly of copolyesters into stereocomplex crystallites tunes the properties of polyester nanoparticlesExterner Link Macromolecules 2020 , 53 , 8340-8351.
F. Schmidt, A. Thywißen, M. Goldmann, C. Cunha, Z. Cseresnyés, H. Schmidt, M. Rafiq, S. Galiani, M. H. Gräler, G. Chamilos, J. F. Lacerda, A. Campos, C. Eggeling, M. T. Figge, T. Heinekamp, S. G. Filler, A. Carvalho, A. A. BrakhageFlotillin-dependent membrane microdomains are required for functional phagolysosomes against fungal infectionsExterner Link Cell Reports 2020 , 32 , 108017.
T. Schuett, J. Kimmig, S. Zechel, U. S. SchubertAutomated polymer purification using dialysisExterner Link Polymers 2020 , 12 , 2095.
M. Sittig, J. C. Tom, J. Elter, F. H. Schacher, B. DietzekQuinoline photobasicity – Investigation within water-soluble light-responsive copolymersExterner Link Chem. Eur. J. 2020 , DOI: 10.1002/chem.202003815.
J. Zhang, B. Farias-Mancilla, I. Kulai, S. Hoeppener, B. Lonetti, S. Prévost, J. Ulbrich, M. Destarac, O. Colombani, U. S. Schubert, C. Guerrero-Sanchez, S. HarrissonEffect of hydrophilic monomer distribution on self-assembly of a pH-responsive copolymer: Spheres, worms and vesicles from a single copolymer compositionExterner Link Angew. Chem. Int. Ed. 2020 , DOI: 10.1002/anie.202010501.
D. Bandelli, I. Muljajew, K. Scheuer, J. B. Max, C. Weber, F. H. Schacher, K. D. Jandt, U. S. SchubertCopolymerization of caprolactone isomers to obtain nanoparticles with constant hydrophobicity and tunable crystallinityExterner Link Macromolecules 2020 , DOI: 10.1021/acs.macromol.0c00486.
B. Böttcher, B. Hoffmann, E. Garbe, T. Weise, Z. Cseresnyés, P. Brandt, S. Dietrich, D. Driesch, M. T. Figge, S. VylkovaThe transcription factor Stp2 is important for Candida albicans biofilm establishment and sustainabilityExterner Link Front. Microbiol. 2020 , 11 , 794.
G. Cinar, C. Englert, M. Lehmann, I. NischangIn situ, quantitative assessment of multifunctional nanoscale drug delivery systems in human serumExterner Link Anal. Chem. 2020 , 92 , 7932-7939.
Z. Cseresnyes, M. I. A. Hassan, H.-M. Dahse, K. Voigt, M. T. FiggeQuantitative impact of cell membrane fluorescence labeling on phagocytosis measurements in confrontation assaysExterner Link Front. Microbiol. 2020 , DOI: 10.3389/fmicb.2020.01193.
M. A. De Jesús-Téllez, D. M. Sánchez-Cerrillo, P. Quintana-Owen, U. S. Schubert, D. Contreras-López, C. Guerrero-SánchezKinetic investigations of quaternization reactions of poly[2-(dimethylamino)ethyl methacrylate] with diverse alkyl halidesExterner Link Macromol. Chem. Phys. 2020 , 221 , 1900543.
A. Medyukhina, M. Blickensdorf, Z. Cseresnyés, N. Ruef, J. V. Stein, M. T. Figge Dynamic spherical harmonics approach for shape classification of migrating cells Sci. Rep. 2020, 10, 6072.
P. Wei, G. Gangapurwala, D. Pretzel, L. Wang, S. Schubert, J. C. Brendel, U. S. SchubertTunable nanogels by host–guest interaction with carboxylate pillar[5]arene for controlled encapsulation and release of doxorubicinExterner Link Nanoscale 2020 , 12 , 13595-13605.
A. Barbotin, I. Urbančič, S. Galiani, C. Eggeling, M. Booth, E. Sezginz-STED imaging and spectroscopy to investigate nanoscale membrane structure and dynamicsExterner Link Biophys. J. 2020 , 118 , 2448-2457.
A. A. Womiloju, C. Höppener, U. S. Schubert, S. HoeppenerMicrowave-assisted synthesis of core–shell nanoparticles - Insights into the growth of different geometriesExterner Link Part. Part. Syst. Charact. 2020 , 2000019.
T. A. Stanly, M. Fritzsche, S. Banerji, D. Shrestha, F. Schneider, C. Eggeling, D. G. JacksonThe cortical actin network regulates avidity-dependent binding of hyaluronan by the Lymphatic Vessel Endothelial receptor LYVE-1Externer Link J. Biol. Chem. 2020 , DOI: 10.1074/jbc.RA1119.011992.
B. Shkodra-Pula, A. Vollrath, U. S. Schubert, S. SchubertPolymer-based nanoparticles for biomedical applicationsExterner Link in Frontiers of Nanoscience , Vol. 16 (Eds.: W. J. Parak, N. Feliu), Elsevier, 2020 , pp. 233-252.
B. Shkodra-Pula, C. Kretzer, P. Jordan, P. Klemm, A. Koeberle, D. Pretzel, E. Banoglu, S. Lorkowski, M. Wallert, S. Hoeppener, S. Stumpf, A. Vollrath, S. Schubert, O. Werz, U. S. SchubertEncapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivityExterner Link J. Nanobiotechnol. 2020 , DOI: 10.21203/rs.21203.rs-15745/v21201.
E. Sezgin, D. Carugo, I. Levental, E. Stride, C. EggelingCreating supported plasma membrane bilayers using acoustic pressureExterner Link bioRxiv 2020 , DOI: 10.1101/2020.1101.1120.912840.
F. Schneider, P. Hernandez-Varas, C. Lagerholm, D. Shrestha, E. Sezgin, J. Roberti, G. Ossato, F. Hecht, C. Eggeling, I. UrbančičHigh photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopyExterner Link J. Phys. D: Appl. Phys. 2020 , 53 , 64003.
F. Richter, L. Martin, K. Leer, E. Moek, F. Hausig, J. C. Brendel, A. TraegerTuning of endosomal escape and gene expression by functional groups, molecular weight and transfection medium: a structure–activity relationship studyExterner Link J. Mater. Chem. B 2020 , DOI: 10.1039/d1030tb00340a.
T. Hanke, S.-Y. Cheung, W. Kilu, J. Heering, X. Ni, V. Planz, S. Schierle, G. Faudone, M. Friedrich, M. Wanior, O. Werz, M. Windbergs, E. Proschak, M. Schubert-Zsilavecz, A. Chaikuad, S. Knapp, D. MerkA selective modulator of peroxisome proliferator-activated receptor γ with an unprecedented binding modeExterner Link J. Med. Chem. 2020 , Doi: 10.1021/acs.jmedchem.1029b01786.
M. Dirauf, C. Grune, C. Weber, U. S. Schubert, D. FischerPoly(ethylene glycol) or poly(2-ethyl-2-oxazoline) – A systematic comparison of PLGA nanoparticles from the bottom upExterner Link Eur. Polym. J. 2020 , 134 , 109801.
M. Dirauf, A. Erlebach, C. Weber, S. Hoeppener, J. R. Buchheim, M. Sierka, U. S. SchubertBlock copolymers composed of PEtOx and polyesteramides based on glycolic acid, L-valine, and L-isoleucineExterner Link Macromolecules 2020 , DOI: 10.1021/acs.macromol.1020c00282.
M. G. Chini, A. Giordano, M. Potenza, S. Terracciano, K. Fischer, M. C. Vaccaro, E. Colarusso, I. Bruno, R. Riccio, A. Koeberle, O. Werz, G. BifulcoTargeting mPGES-1 by a combinatorial approach: Identification of the aminobenzothiazole scaffold to suppress PGE2 levelsExterner Link ACS Med. Chem. Lett. 2020 , DOI: 10.1021/acsmedchemlett.1029b00618.
P. Carravilla, J. L. Nieva, C. EggelingFluorescence microscopy of the HIV-1 envelopeExterner Link Viruses 2020 , 12 , 348.
A. Barbotin, I. Urbančič, S. Galiani, C. Eggeling, M. BoothBackground reduction in STED-FCS using coherent-hybrid STEDExterner Link bioRxiv 2020 , DOI: 10.1101/2020.1101.1106.895243.
J. Alex, K. González, T. Kindel, P. Bellstedt, C. Weber, T. Heinekamp, T. Orasch, C. Guerrero-Sanchez, U. S. Schubert, A. A. BrakhageCaspofungin functionalized polymethacrylates with antifungal propertiesExterner Link Biomacromolecules 2020 , DOI: 10.1021/acs.biomac.0c00096.
H. Lindemann, M. Kühne, C. Grune, P. Warncke, S. Hofmann, A. Koschella, M. Godmann, D. Fischer, T. Heinzel, T. HeinzePolysaccharide nanoparticles bearing HDAC inhibitor as nontoxic nanocarrier for drug deliveryExterner Link Macromol. Biosci. 2020 , 2000039.
M. Grube, I. Perevyazko, T. Heinze, U. S. Schubert, I. Nischang,Revisiting very disperse macromolecule populations in hydrodynamic and light scattering studies of sodium carboxymethyl cellulosesExterner Link Carbohydr. Polym. 2020 , 229 , 115452.
S. C. Koeberle, A. Gollowitzer, J. Laoukili, O. Kranenburg, O. Werz, A. Koeberle, A. P. KippDistinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanismsExterner Link Redox Biology 2020 , 28 , 101388.
I. Muljajew, A. Erlebach, C. Weber, J. R. Buchheim, M. Sierka, U. S. SchubertA polyesteramide library from dicarboxylic acids and 2,2′-bis(2-oxazoline): synthesis, characterization, nanoparticle formulation and molecular dynamics simulationsExterner Link Polym. Chem. 2020 , 11 , 112-124.
M. Werner, S. Pace, A. Czapka, P. M. Jordan, J. Gerstmeier, A. Koeberle, O. WerzCommunication between human macrophages and epithelial cancer cell lines dictates lipid mediator biosynthesisExterner Link Cell. Mol. Life Sci. 2020 , DOI: 10.1007/s00018-00019-03413-w.
T. Wloka, S. Czich, M. Kleinsteuber, E. Moek, C. Weber, M. Gottschaldt, K. Liefeith, U. S. SchubertMicrofabrication of 3D-hydrogels via two-photon polymerization of poly(2-ethyl-2-oxazoline) diacrylatesExterner Link Eur. Polym. J. 2020 , 122 , 109295.
A. M. Ali, T. Deckert-Gaudig, M. Egiza, V. Deckert, T. YoshitakeNear- and far-field Raman spectroscopic studies of nanodiamond composite films deposited by coaxial arc plasmaExterner Link Appl. Phys. Lett. 2020 , 116 , 041601.
C. Chen, F. Richter, C. Guerrero-Sanchez, A. Traeger, U. S. Schubert, A. Feng, S. H. ThangCell-penetrating, peptide-based RAFT agent for constructing penetration enhancersExterner Link ACS Macro Letters 2020 , 9 , 260-265.
C. Cokca, L. Zartner, I. Tabujew, D. Fischer, K. PenevaIncorporation of indole significantly improves the transfection efficiency of guanidinium-containing poly(methacrylamide)sExterner Link Macromol. Rapid Commun. 2020 , 41 , 2070012.
J. A. Czaplewska, G. Gangapurwala, A. Vollrath, M. Pröhl, T. Majdanski, D. Pretzel, S. Hoeppener, U. S. Schubert, M. GottschaldtSynthesis of a fructose decorated PAGE-b-PEG-b-PLGA polymer with subsequent formulation of nanoparticlesExterner Link Colloids Surf. A Physicochem. Eng. Asp. 2020 , 124701.
S. Deinhardt-Emmer, K. Rennert, E. Schicke, Z. Cseresnyés, M. Windolph, S. Nietzsche, R. Heller, F. Siwczak, K. F. Haupt, S. Carlstedt, M. Schacke, M. T. Figge, C. Ehrhardt, B. Löffler, A. S. MosigCo-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip modelExterner Link Biofabrication 2020 , 12 , 025012.
A. Erlebach, I. Muljajew, M. Chi, C. Bückmann, C. Weber, U. S. Schubert, M. SierkaPredicting solubility of small molecules in macromolecular compounds for nanomedicine application from atomistic simulationsExterner Link Adv. Theory Simul. 2020 , DOI: 10.1002/adts.202000001.
E. Gardey, F. H. Sobotta, S. Hoeppener, T. Bruns, A. Stallmach, J. C. BrendelInfluence of core cross-linking and shell composition of polymeric micelles on immune response and their interaction with human monocytesExterner Link Biomacromolecules 2020 , DOI: 10.1021/acs.biomac.9b01656.
M. Gericke, P. Schulze, T. HeinzeNanoparticles based on hydrophobic polysaccharide derivatives—formation principles, characterization techniques, and biomedical applicationsExterner Link Macromol. Biosci. 2020 , 1900415.
M. Grube, G. Cinar, U. S. Schubert, I. NischangIncentives of using the hydrodynamic invariant and sedimentation parameter for the study of naturally- and synthetically-based macromolecules in solutionExterner Link Polymers 2020 , 12 , 277.
K. Hiesinger, A. Schott, J. S. Kramer, R. Blöcher, F. Witt, S. K. Wittmann, D. Steinhilber, D. Pogoryelov, J. Gerstmeier, O. Werz, E. ProschakDesign of dual inhibitors of soluble epoxide hydrolase and LTA4 hydrolaseExterner Link ACS Med. Chem. Lett. 2020 , 11 , 298-302.
C. Höppener, F. H. Schacher, V. DeckertMultimodal characterization of resin embedded and sliced polymer nanoparticles by means of tip-enhanced raman spectroscopy and force–distance curve based atomic force microscopyExterner Link Small 2020 , 1907418.
J. Hübner, T. Deckert-Gaudig, J. Glorian, V. K. Deckert, D. SpitzerSurface characterization of nanoscale co-crystals enabled through tip enhanced raman spectroscopyExterner Link Nanoscale 2020 , DOI: 10.1039/D1030NR00397B.
S. M. A. S. Keshk, A. A. El-Zahhar, Q. A. Alsulami, M. Jaremko, S. Bondock, T. HeinzeSynthesis, characterization and ampyrone drug release behavior of magnetite nanoparticle/2,3-dialdehyde cellulose-6-phosphate compositeExterner Link Cellulose 2020 , 27 , 1603-1618.
A. Koschella, C.-Y. Chien, T. Iwata, M. S. Thonhofer, T. M. Wrodnigg, T. HeinzeAll sugar based cellulose derivatives synthesized by azide–alkyne click chemistryExterner Link Macromol. Chem. Phys. 2020 , 221 , 1900343.
G. Lauro, S. Terracciano, V. Cantone, D. Ruggiero, K. Fischer, S. Pace, O. Werz, I. Bruno, G. BifulcoA combinatorial virtual screening approach driving the synthesis of 2,4-thiazolidinedione-based molecules as new dual mPGES-1/5-LO inhibitorsExterner Link ChemMedChem 2020 , 15 , 481-489.
V. D. Lechuga-Islas, G. Festag, M. Rosales-Guzmán, O. E. Vega-Becerra, R. Guerrero-Santos, U. S. Schubert, C. Guerrero-SánchezQuasi-block copolymer design of quaternized derivatives of poly(2-(dimethylamino)ethyl methacrylate): Investigations on thermo-induced self-assemblyExterner Link Eur. Polym. J. 2020 , 124 , 109457.
E. Matuszyk, E. Sierka, M. Rodewald, H. Bae, T. Meyer, E. Kus, S. Chlopicki, M. Schmitt, J. Popp, M. BaranskaDifferential response of liver sinusoidal endothelial cells and hepatocytes to oleic and palmitic acid revealed by Raman and CARS imagingExterner Link Biochim. Biophys. Acta Mol. Basis Disease 2020 , 1866 , 165763.
J. B. Max, P. J. Mons, J. C. Tom, F. H. SchacherDouble hydrophilic poly(ethylene oxide)-block-poly(dehydroalanine) block copolymers: Comparison of two different synthetic routesExterner Link Macromol. Chem. Phys. 2020 , 221 , 1900383.
A. Olgac, A. Carotti, C. Kretzer, S. Zergiebel, A. Seeling, U. Garscha, O. Werz, A. Macchiarulo, E. BanogluDiscovery of novel 5-lipoxygenase-activating protein (FLAP) inhibitors by exploiting a multistep virtual screening protocolExterner Link J. Chem. Inf. Model. 2020 , 60 , 1737-1748.
Z. Rao, P. M. Jordan, Y. Wang, D. Menche, S. Pace, J. Gerstmeier, O. WerzDifferential role of vacuolar (H+)-ATPase in the expression and activity of cyclooxygenase-2 in human monocytesExterner Link Biochem. Pharmacol. 2020 , 175 , 113858.
V. V. Shumyantseva, T. V. Bulko, A. V. Kuzikov, R. A. Masamrekh, A. Y. Konyakhina, I. Romanenko, J. B. Max, M. Köhler, A. A. Gilep, S. A. Usanov, D. V. Pergushov, F. H. Schacher, L. V. SigolaevaAll-electrochemical nanocomposite two-electrode setup for quantification of drugs and study of their electrocatalytical conversion by cytochromes P450Externer Link Electrochimica Acta 2020 , 336 , 135579.
P. Singh, T. Deckert-Gaudig, Z. Zhang, V. DeckertPlasmon induced deprotonation of 2-mercaptopyridineExterner Link Analyst 2020 , 145 , 2106-2110.
M. Sittig, B. Schmidt, H. Görls, T. Bocklitz, M. Wächtler, S. Zechel, M. D. Hager, B. DietzekFluorescence upconversion by triplet-triplet annihilation in all-organic poly(methacrylate)-terpolymersExterner Link Phys. Chem. Chem. Phys. 2020 , 22 , 4072-4079.
R. Takahashi, S. Miwa, F. H. Sobotta, J. H. Lee, S. Fujii, N. Ohta, J. C. Brendel, K. SakuraiUnraveling the kinetics of the structural development during polymerization-induced self-assembly: decoupling the polymerization and the micelle structureExterner Link Polym. Chem. 2020 , 11 , 1514-1524.
A. Traeger, S. Voelker, B. Shkodra-Pula, C. Kretzer, S. Schubert, M. Gottschaldt, U. S. Schubert, O. WerzImproved bioactivity of the natural product 5-lipoxygenase inhibitor hyperforin by encapsulation into polymeric nanoparticlesExterner Link Mol. Pharm. 2020 , 17 , 810-816.
P. Wei, J. A. Czaplewska, L. Wang, S. Schubert, J. C. Brendel, U. S. SchubertStraightforward access to glycosylated, acid sensitive nanogels by host–guest interactions with sugar-modified pillar[5]arenesExterner Link ACS Macro Letters 2020 , 9 , 540-545.
P. Wei, F. H. Sobotta, C. Kellner, D. Bandelli, S. Hoeppener, S. Schubert, J. C. Brendel, U. S. SchubertDegradable polycaprolactone nanoparticles stabilized via supramolecular host–guest interactions with pH-responsive polymer-pillar[5]arene conjugatesExterner Link Polym. Chem. 2020 , 11 , 1985-1997.
F. Wendler, J. C. Tom, M. Sittig, P. Biehl, B. Dietzek, F. H. SchacherBlock copolymers featuring highly photostable photoacids based on vinylnaphthol: Synthesis and self-assemblyExterner Link Macromol. Rapid Commun. 2020 , 41 , 1900607.
2019
N. Köse-Vogel, S. Stengel, E. Gardey, T. Kirchberger-Tolstik, P. A. Reuken, A. Stallmach, T. BrunsTranscriptional suppression of the NLRP3 inflammasome and cytokine release in primary macrophages by low-dose anthracyclinesExterner Link Cells 2019 , 9 , 79.
G. Creusen, A. Roshanasan, J. Garcia Lopez, K. Peneva, A. WaltherBottom-up design of model network elastomers and hydrogels from precise star polymersExterner Link Polym. Chem. 2019 , 10 , 3740-3750.
F. Wendler, J. C. Tom, F. H. SchacherSynthesis and self-assembly of photoacid-containing block copolymers based on 1-naphtholExterner Link Polym. Chem. 2019 , 10 , 5602-5616.
D. Bandelli, J. Alex, C. Weber, U. S. SchubertPolyester stereocomplexes beyond PLA: Could synthetic opportunities revolutionize established material blending?Externer Link Macromol. Rapid Commun. 2019 , 1900560.
T. Chakraborty, M. K. Driscoll, E. Jeffery, M. M. Murphy, P. Roudot, B.-J. Chang, S. Vora, W. M. Wong, C. D. Nielson, H. Zhang, V. Zhemkov, C. Hiremath, E. D. De La Cruz, Y. Yi, I. Bezprozvanny, H. Zhao, R. Tomer, R. Heintzmann, J. P. Meeks, D. K. Marciano, S. J. Morrison, G. Danuser, K. M. Dean, R. FiolkaLight-sheet microscopy of cleared tissues with isotropic, subcellular resolutionExterner Link Nat. Meth. 2019 , 16 , 1109-1113.
C. Favard, J. Chojnacki, P. Merida, N. Yandrapalli, J. Mak, C. Eggeling, D. MuriauxHIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assemblyExterner Link Sci. Adv. 2019 , 5 , eaaw8651.
E. Romp, V. Arakandy, J. Fischer, C. Wolz, A. Siegmund, B. Löffler, L. Tuchscherr, O. Werz, U. GarschaExotoxins from Staphylococcus aureus activate 5-lipoxygenase and induce leukotriene biosynthesisExterner Link Cell. Mol. Life Sci. 2019 , DOI: 10.1007/s00018-00019-03393-x.
M. Rosales-Guzmán, O. Pérez-Camacho, C. Guerrero-Sánchez, S. Harrisson, R. Torres-Lubián, J. Vitz, U. S. Schubert, E. Saldívar-GuerraSemiautomated parallel RAFT copolymerization of isoprene with glycidyl methacrylateExterner Link ACS Comb. Sci. 2019 , 21 , 771-781.
F. Wendler, M. Sittig, J. C. Tom, B. Dietzek, F. H. SchacherPolymeric photoacids based on naphthols - Design criteria, photostability, and light-mediated releaseExterner Link Chem. Eur. J. 2019 , DOI: 10.1002/chem.201903819.
R. Meyer, S. Trautmann, K. Rezaei, A. George, A. Turchanin, V. DeckertSynergy of photoinduced force microscopy and tip-enhanced Raman spectroscopy—A correlative study on MoS2Externer Link ACS Photonics 2019 , 6 , 1191-1198.
J. B. Max, D. V. Pergushov, L. V. Sigolaeva, F. H. SchacherPolyampholytic graft copolymers based on polydehydroalanine (PDha) – synthesis, solution behavior and application as dispersants for carbon nanotubesExterner Link Polym. Chem. 2019 , 10 , 3006-3019.
J. Langer, D. Jimenez de Aberasturi, J. Aizpurua, R. A. Alvarez-Puebla, B. Auguié, J. J. Baumberg, G. C. Bazan, S. E. J. Bell, A. Boisen, A. G. Brolo, J. Choo, D. Cialla-May, V. Deckert, L. Fabris, K. Faulds, F. J. García de Abajo, R. Goodacre, D. Graham, A. J. Haes, C. L. Haynes, C. Huck, T. Itoh, M. Käll, J. Kneipp, N. A. Kotov, H. Kuang, E. C. Le Ru, H. K. Lee, J.-F. Li, X. Y. Ling, S. Maier, T. Mayerhoefer, M. Moskovits, K. Murakoshi, J.-M. Nam, S. Nie, Y. Ozaki, I. Pastoriza-Santos, J. Perez-Juste, J. Popp, A. Pucci, S. Reich, B. Ren, G. C. Schatz, T. Shegai, S. Schlücker, T. Li-Lin, K. G. Thomas, Z.-Q. Tian, R. P. Van Duyne, T. Vo-Dinh, Y. Wang, K. A. Willets, C. Xu, H. Xu, Y. Xu, Y. S. Yamamoto, B. Zhao, L. M. Liz-MarzánPresent and future of surface enhanced Raman scatteringExterner Link ACS Nano 2019 , DOI: 10.1021/acsnano.1029b04224.
J. Ernst, M. Klinger-Strobel, J. Thamm, O. Makarewicz, M. Pletz, D. Fischer Breaking the biofilm barrier: The role of stabilizers in biofilm penetration and pulmonary antibiotic delivery by polymer nanoparticlesPharmazeutische Industrie 2019 , 81 , 248-255.
J. K. Elter, P. Biehl, M. Gottschaldt, F. H. SchacherCore-crosslinked worm-like micelles from polyether-based diblock terpolymersExterner Link Polym. Chem. 2019 , DOI: 10.1039/C1039PY01054H.
V. H. Bac, B. S. Paulsen, L. V. Truong, A. Koschella, T. C. Trinh, C. W. Wold, S. Yogarajah, T. HeinzeNeutral polysaccharide from the leaves of pseuderanthemum carruthersii: Presence of 3-O-methyl galactose and anti-inflammatory activity in LPS-stimulated RAW 264.7 cellsExterner Link Polymers 2019 , 11 , 1219.
L. Applová, J. Karlíčková, P. Warncke, K. Macáková, M. Hrubša, M. Macháček, V. Tvrdý, D. Fischer, P. Mladěnka4-Methylcatechol, a flavonoid metabolite with potent antiplatelet effectsExterner Link Mol. Nutr. Food Res. 2019 , 63 , 1900261.
I. Perevyazko, A. Lezov, A. S. Gubarev, E. Lebedeva, G. Festag, C. Guerrero-Sanchez, N. Tsvetkov, U. S. SchubertStructure-property relationships via complementary hydrodynamic approaches: Poly(2-(dimethylamino)ethyl methacrylate)sExterner Link Polymer 2019 , 182 , 121828.
L. V. Sigolaeva, T. V. Bulko, M. S. Kozin, W. Zhang, M. Köhler, I. Romanenko, J. Yuan, F. H. Schacher, D. V. Pergushov, V. V. ShumyantsevaLong-term stable poly(ionic liquid)/MWCNTs inks enable enhanced surface modification for electrooxidative detection and quantification of dsDNAExterner Link Polymer 2019 , 168 , 95-103.
C. St Thomas, C. N. Muñoz López, E. J. Jiménez Regalado, M. A. de Jesús Tellez, G. Festag, U. S. Schubert, C. Guerrero-SánchezPreparation of hydrophobically modified associating multiblock copolymers via a one-pot aqueous RAFT polymerizationExterner Link Polym. Chem. 2019 , DOI: 10.1039/C1039PY01311C.
M. Wang, J. Zhang, C. Guerrero-Sanchez, U. S. Schubert, A. Feng, S. H. ThangEnzyme degassing for oxygen-sensitive reactions in open vessels of an automated parallel synthesizer: RAFT polymerizationsExterner Link ACS Comb. Sci. 2019 , 21 , 643-649.
M. Wallert, M. Ziegler, X. Wang, A. Maluenda, X. Xu, M. L. Yap, R. Witt, C. Giles, S. Kluge, M. Hortmann, J. Zhang, P. Meikle, S. Lorkowski, K. Peterα-Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injuryExterner Link Redox Biology 2019 , 26 , 101292.
H. L. Cao, X. Y. Liu, K. D. JandtThe action-network of nanomaterialsExterner Link in "On the issue of transparency and reproducibility in nanomedicine"Externer Link Nat. Nanotechn. 2019 , 14 , 629-635.
D. Bandelli, C. Weber, U. S. SchubertStrontium isopropoxide: A highly active catalyst for the ring-opening polymerization of lactide and various lactonesExterner Link Macromol. Rapid Commun. 2019 , 1900306.
Z. Rao, S. Pace, P. M. Jordan, R. Bilancia, F. Troisi, F. Börner, N. Andreas, T. Kamradt, D. Menche, A. Rossi, C. N. Serhan, J. Gerstmeier, O. WerzVacuolar (H+)-ATPase critically regulates specialized proresolving mediator pathways in human M2-like monocyte-derived macrophages and has a crucial role in resolution of inflammationExterner Link J. Immunol. 2019 , 203 , 1031-1043.
H. Würfel, M. Kayser, T. HeinzeNon-aqueous solvent for efficient dissolution of polygalacturonic acidExterner Link Carbohydr. Polym. 2019 , 207 , 791-795.
H. Würfel, M. Kayser, T. HeinzeTrimethylsilylation of Polygalacturonic AcidExterner Link Macromol. Chem. Phys. 2019 , 220 , 1900002.
M. Kostag, M. Gericke, T. Heinze, O. A. El SeoudTwenty-five years of cellulose chemistry: innovations in the dissolution of the biopolymer and its transformation into esters and ethersExterner Link Cellulose 2019 , 26 , 139-184.
C. Pinon-Balderrama, C. Leyva-Porras, R. Olayo-Valles, J. Revilla-Vazquez, U. S. Schubert, C. Guerrero-Sanchez, J. Bonilla-CruzSelf-assembly investigations of sulfonated poly(methyl methacrylate-block-styrene) diblock copolymer thin filmsExterner Link Adv. Polym. Technol. 2019 , 2019 , 11.
A. Sierra-Fernandez, S. C. De la Rosa-García, R. Yañez-Macías, C. Guerrero-Sanchez, L. S. Gomez-Villalba, S. Gómez-Cornelio, M. E. Rabanal, U. S. Schubert, R. Fort, P. QuintanaSol–gel synthesis of Mg(OH)2 and Ca(OH)2 nanoparticles: a comparative study of their antifungal activity in partially quaternized p(DMAEMA) nanocomposite filmsExterner Link J. Sol-Gel Sci. Technol. 2019 , 89 , 310-321.
M. Zink, K. Hotzel, U. S. Schubert, T. Heinze, D. FischerAmino Acid–Substituted Dextran-Based Non-Viral Vectors for Gene DeliveryExterner Link Macromol. Biosci. 2019 , 19 , 1900085.
J. Gerstmeier, C. Kretzer, S. Di Micco, L. Miek, H. Butschek, V. Cantone, R. Bilancia, R. Rizza, F. Troisi, N. Cardullo, C. Tringali, A. Ialenti, A. Rossi, G. Bifulco, O. Werz, S. PaceNovel benzoxanthene lignans that favorably modulate lipid mediator biosynthesis: A promising pharmacological strategy for anti-inflammatory therapyExterner Link Biochem. Pharmacol. 2019 , 165 , 263-274.
J. Gerstmeier, J. Seegers, F. Witt, B. Waltenberger, V. Temml, J. M. Rollinger, H. Stuppner, A. Koeberle, D. Schuster, O. WerzGinkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator BiosynthesisExterner Link Frontiers in Pharmacology 2019 , 10.
S. Shekfeh, B. Çalışkan, K. Fischer, T. Yalçın, U. Garscha, O. Werz, E. BanogluA Multi‐step Virtual Screening Protocol for the Identification of Novel Non‐acidic Microsomal Prostaglandin EExterner Link 2 Synthase‐1 (mPGES‐1) InhibitorsExterner Link ChemMedChem 2019 , 14 , 273-281.
M. Wallert, J. Bauer, S. Kluge, L. Schmölz, Y.-C. Chen, M. Ziegler, A. K. Searle, A. Maxones, M. Schubert, M. Thürmer, H. Pein, A. Koeberle, O. Werz, M. Birringer, K. Peter, S. LorkowskiThe vitamin E derivative garcinoic acid fromExterner Link Garcinia kola nut seeds attenuates the inflammatory responseExterner Link Redox Biology 2019 , 24 , 101166.
M. Reifarth, W. Müller, B. Shkodra-Pula, H. Görls, U. S. Schubert, R. Heintzmann, S. HoeppenerElectron density of polymeric nanoparticles determined by image processing of transmission electron micrographs: Insights into heavy metal staining processesExterner Link Particle & Particle Systems Characterization 2019 , 1800324.
M. Sahn, C. Weber, U. S. SchubertPoly(2-oxazoline)-containing triblock copolymers: Synthesis and applicationsExterner Link Polym. Rev. 2019 , doi: 10.1080/15583724.2018.1496930.
P. Wei, G. Gangapurwala, D. Pretzel, M. N. Leiske, L. Wang, S. Hoeppener, S. Schubert, J. C. Brendel, U. S. SchubertSmart pH-sensitive nanogels for controlled release in an acidic environmentExterner Link Biomacromolecules 2019 , 20 , 130-140.
M. Werner, P. M. Jordan, E. Romp, A. Czapka, Z. Rao, C. Kretzer, A. Koeberle, U. Garscha, S. Pace, H.-E. Claesson, C. N. Serhan, O. Werz, J. GerstmeierTargeting biosynthetic networks of the proinflammatory and proresolving lipid metabolomeExterner Link The FASEB Journal 2019 , doi: 10.1096/fj.201802509R.
L. Wondraczek, G. Pohnert, F. H. Schacher, A. Köhler, M. Gottschaldt, U. S. Schubert, K. Küsel, A. A. BrakhageArtificial microbial arenas: Materials for observing and manipulating microbial consortiaExterner Link Adv. Mater. 2019 , 31 , 1900284.
B. Shkodra-Pula, C. Grune, A. Traeger, A. Vollrath, S. Schubert, D. Fischer, U. S. SchubertEffect of surfactant on the size and stability of PLGA nanoparticles encapsulating a protein kinase C inhibitorExterner Link Int. J. Pharm. 2019 , 566 , 756-764.
C. Reichardt, S. Monro, F. H. Sobotta, K. L. Colón, T. Sainuddin, M. Stephenson, E. Sampson, J. Roque, H. Yin, J. C. Brendel, C. G. Cameron, S. McFarland, B. DietzekPredictive strength of photophysical measurements for in vitro photobiological activity in a series of Ru(II) polypyridyl complexes derived from π-extended ligandsExterner Link Inorg. Chem. 2019 , 58 , 3156-3166.
H. Qiu, Z. Yang, M. Köhler, J. Ling, F. H. SchacherSynthesis and solution self-assembly of poly(1,3-dioxolane)Externer Link Macromolecules 2019 , 52 , 3359-3366.
N. Engel, M. Dirauf, S. Seupel, M. N. Leiske, S. Schubert, U. S. SchubertUtilization of 4-(trifluoromethyl)benzenesulfonates as counter ions tunes the initiator efficiency of sophisticated initiators for the preparation of well-defined poly(2-oxazoline)sExterner Link Macromol. Rapid Commun. 2019 , 40 , 1900094.
N. Al Nakeeb, I. Nischang, B. V. K. J. SchmidtTannic acid-mediated aggregate stabilization of poly(N-vinylpyrrolidone)-b-poly(oligo (ethylene glycol) methyl ether methacrylate) double hydrophilic block copolymersExterner Link Nanomaterials 2019 , 9 , 662.
M. Maurer, M. S. Gresnigt, A. Last, T. Wollny, F. Berlinghof, R. Pospich, Z. Cseresnyes, A. Medyukhina, K. Graf, M. Gröger, M. Raasch, F. Siwczak, S. Nietzsche, I. D. Jacobsen, M. T. Figge, B. Hube, O. Huber, A. S. MosigA three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studiesExterner Link Biomaterials 2019 , 220 , 119396.
M. I. A. Hassan, Z. Cseresnyes, N. Al-Zaben, H.-M. Dahse, R. J. Vilela de Oliveira, G. Walther, K. Voigt, M. T. FiggeThe geographical region of origin determines the phagocytic vulnerability of Lichtheimia strainsExterner Link Environ. Microbiol. , DOI: 10.1111/1462-2920.14752.
D. Bandelli, J. Alex, C. Helbing, N. Ueberschaar, H. Görls, P. Bellstedt, C. Weber, K. D. Jandt, U. S. SchubertPoly(ethylglycolide): A well-defined polyester matching the hydrophilic hydrophobic balance of PLAExterner Link Polym. Chem. 2019 , DOI: 10.1039/c1039py00875f.
I. Tabujew, C. Cokca, L. Zartner, U. S. Schubert, I. Nischang, D. Fischer, K. PenevaThe influence of gradient and statistical arrangements of guanidinium or primary amine groups in poly(methacrylate) copolymers on their DNA binding affinityExterner Link Journal of Materials Chemistry B 2019, DOI: 10.1039/c9tb01269a.
A. Barbotin, S. Galiani, I. Urbančič, C. Eggeling, M. J. BoothAdaptive optics allows STED-FCS measurements in the cytoplasm of living cellsExterner Link Optics Express 2019 , 27 , 23378-23395.
T. Klein, F. V. Gruschwitz, S. Rogers, S. Hoeppener, I. Nischang, J. C. BrendelThe influence of directed hydrogen bonds on the self-assembly of amphiphilic polymers in waterExterner Link J. Colloid Interface Sci. 2019 , 557 , 488-497.
M. E. Mikhailova, A. S. Senchukova, A. A. Lezov, A. S. Gubarev, A.-K. Trützschler, U. S. Schubert, N. V. TsvetkovStabilization of Silver Nanoparticles by Cationic Aminoethyl Methacrylate Copolymers in Aqueous Media—Effects of Component Ratios and Molar Masses of CopolymersExterner Link Polymers 2019 , 11 , 1647.
M. Raasch, E. Fritsche, A. Kurtz, M. Bauer, A. S. MosigMicrophysiological systems meet hiPSC technology - New tools for disease modeling of liver infections in basic research and drug developmentExterner Link Adv. Drug Delivery Rev. 2019 , 140 , 51-67.
E. Rossegger, F. Pirolt, S. Hoeppener, U. S. Schubert, O. Glatter, F. WiesbrockCrosslinkable/functionalizable poly(2-oxazoline)based micellesExterner Link Eur. Polym. J. 2019 , 121 , 109305.
I. Tabujew, M. Heidari, C. Freidel, M. Helm, L. Tebbe, U. Wolfrum, K. Nagel-Wolfrum, K. Koynov, P. Biehl, F. H. Schacher, R. Potestio, K. PenevaTackling the limitations of copolymeric small interfering RNA delivery agents by a combined experimental–computational approachExterner Link Biomacromolecules 2019 , 20 , 4389-4406.
I. Tabujew, M. Willig, N. Leber, C. Freidel, I. Negwer, K. Koynov, M. Helm, K. Landfester, R. Zentel, K. Peneva, V. MailänderOvercoming the barrier of CD8+ T cells: Two types of nano-sized carriers for siRNA transportExterner Link Acta Biomaterialia 2019 , 100 , 338-351.
R. Yañez-Macías, A. Muñoz-Bonilla, M. A. De Jesús-Tellez, H. Maldonado-Textle, C. Guerrero-Sánchez, U. S. Schubert, R. Guerrero-SantosCombinations of antimicrobial polymers with nanomaterials and bioactives to improve biocidal therapiesExterner Link Polymers 2019 , 11 , 1789.
M. Yarbakht, P. Pradhan, N. Köse-Vogel, H. Bae, S. Stengel, T. Meyer, M. Schmitt, A. Stallmach, J. Popp, T. W. Bocklitz, T. BrunsNonlinear multimodal imaging characteristics of early septic liver injury in a mouse model of peritonitisExterner Link Anal. Chem. 2019 , 91 , 11116-11121.
2018
F. L. Kriegel, R. Köhler, J. Bayat-Sarmadi, S. Bayerl, A. E. Hauser, R. Niesner, A. Luch, Z. CseresnyesMorphology-based distinction between healthy and pathological cells utilizing fourier transforms and self-organizing mapsExterner Link JoVE 2018 , e58543.
N. Teich, T. Bruns, A. StallmachLetter: predicting azathioprine-associated pancreatitis in IBD—phenotype or genotype?Externer Link Aliment. Pharmacol. Ther. 2018 , 47 , 1042-1043.
C. Englert, J. C. Brendel, T. C. Majdanski, T. Yildirim, S. Schubert, M. Gottschaldt, N. Windhab, U. S. Schubert, "Pharmapolymers in the 21st Century: Synthetic Polymers in Drug Delivery ApplicationsExterner Link ", Prog. Polym. Sci. 2018 , DOI: 10.1016/j.progpolymsci.2018.1007.1005.
P. Dasari, I. A. Shopova, M. Stroe, D. Wartenberg, H. Martin-Dahse, N. Beyersdorf, P. Hortschansky, S. Dietrich, Z. Cseresnyés, M. T. Figge, M. Westermann, C. Skerka, A. A. Brakhage, P. F. Zipfel, "Aspf2 from Aspergillus fumigatus recruits human immune regulators for immune evasion and cell damageExterner Link ", Front. Immunol. 2018 , 9 , 1635.
L. Vieider, E. Romp, V. Temml, J. Fischer, C. Kretzer, M. Schoenthaler, A. Taha, V. Hernández-Olmos, S. Sturm, D. Schuster, O. Werz, U. Garscha, B. Matuszczak, "Synthesis, biological evaluation and structureactivity relationships of diflapolin analogues as dual sEH/FLAP inhibitorsExterner Link ", ACS Med. Chem. Lett. 2018 , DOI: 10.1021/acsmedchemlett.8b00415.
M. Brunzel, T. Majdanski, J. Vitz, I. Nischang, U. Schubert, "Fast screening of diol impurities in methoxy poly(ethylene glycol)s (mPEG)s by liquid chromatography on monolithic silica rodsExterner Link ", Polymers 2018 , 10 , 1395.
T. C. Majdanski, J. Vitz, A. Meier, M. Brunzel, S. Schubert, I. Nischang, U. S. Schubert, "Green ethers as solvent alternatives for anionic ring-opening polymerizations of ethylene oxide (EO): In-situ kinetic and advanced characterization studiesExterner Link ", Polymer 2018 , 159 , 86-94.
M. Dirauf, D. Bandelli, C. Weber, H. Görls, M. Gottschaldt, U. S. Schubert, "TBD-catalyzed ring-opening polymerization of alkyl-substituted morpholine-2,5-dione derivativesExterner Link ", Macromol. Rapid Commun. 2018 , 39 , 1800433.
H. Pein, A. Ville, S. Pace, V. Temml, U. Garscha, M. Raasch, K. Alsabil, G. Viault, C.-P. Dinh, D. Guilet, F. Troisi, K. Neukirch, S. König, R. Bilancia, B. Waltenberger, H. Stuppner, M. Wallert, S. Lorkowski, C. Weinigel, S. Rummler, M. Birringer, F. Roviezzo, L. Sautebin, J.-J. Helesbeux, D. Séraphin, A. Mosig, D. Schuster, A. Rossi, P. Richomme, O. Werz, A. Koeberle, "Endogenous metabolites of vitamin E limit inflammation by targeting 5 lipoxygenaseExterner Link ", Nat. Commun. 2018 , 9 , 3834.
H. Würfel, M. Kayser, T. Heinze, "Efficient and catalyst-free synthesis of cellulose acetoacetatesExterner Link ", Cellulose 2018 , 25 , 4919-4928.
K. Ganske, T. Heinze, "Evaluation of the synthesis of soluble aromatic cellulose carbonates of low degree of substitutionExterner Link ",Macromol. Chem. Phys. 2018 , 219 , 1800152.
T. Bus, A. Traeger, U. S. Schubert, "The great escape: how cationic polyplexes overcome the endosomal barrierExterner Link ", J. Mater. Chem. B 2018 , 6 , 6904-6918.
M. Bauer, L. Tauhardt, H. M. L. Lambermont-Thijs, K. Kempe, R. Hoogenboom, U. S. Schubert, D. Fischer, "Rethinking the impact of the protonable amine density on cationic polymers for gene delivery: A comparative study of partially hydrolyzed poly(2-ethyl-2-oxazoline)s and linear poly(ethylene imine)sExterner Link ", Eur. J. Pharm. Biopharm. 2018 , 133 , 112-121.
J. F. Herrmann, C. Höppener, "Dumbbell gold nanoparticle dimer antennas with advanced optical propertiesExterner Link ", Beilst. J. Nanotechnol. 2018 , 9 , 2188-2197.
R. Meyer, X. Yao, V. Deckert, "Latest instrumental developments and bioanalytical applications in tip-enhanced Raman spectroscopyExterner Link ", Trends Anal. Chem. 2018 , 102 , 250-258.
D. Bandelli, C. Helbing, C. Weber, M. Seifert, I. Muljajew, K. D. Jandt, U. S. Schubert, "Maintaining the hydrophilichydrophobic balance of polyesters with adjustable crystallinity for tailor-made nanoparticlesExterner Link ", Macromolecules 2018 , 51 , 5567-5576.
S.-Y. Cheung, M. Werner, L. Esposito, F. Troisi, V. Cantone, S. Liening, S. König, J. Gerstmeier, A. Koeberle, R. Bilancia, R. Rizza, A. Rossi, F. Roviezzo, V. Temml, D. Schuster, H. Stuppner, M. Schubert-Zsilavecz, O. Werz, T. Hanke, S. Pace, "Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammationExterner Link ", Eur. J. Med. Chem. 2018 , 156 , 815-830.
A. Koeberle, A. Henkel, M. Verhoff, L. Tausch, S. König, D. Fischer, N. Kather, S. Seitz, M. Paul, J. Jauch, O. Werz, "Triterpene acids from Frankincense and semi-synthetic derivatives that inhibit 5-lipoxygenase and cathepsin GExterner Link ", Molecules 2018 , 23 , 506.
A.-K. Trützschler, T. Bus, M. Sahn, A. Traeger, C. Weber, U. S. Schubert, "The power of shielding: Low toxicity and high transfection performance of cationic graft copolymers containing poly(2-oxazoline) side chainsExterner Link ", Biomacromolecules 2018 , 19 , 2759-2771.
M. Grube, M. N. Leiske, U. S. Schubert, I. Nischang, "POx as an alternative to PEG? A hydrodynamic and light scattering studyExterner Link ", Macromolecules 2018 , 51 , 1905-1916.
Z. T. Gür, B. Çalışkan, U. Garscha, A. Olgaç, U. S. Schubert, J. Gerstmeier, O. Werz, E. Banoglu, "Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7Externer Link ", Eur. J. Med. Chem. 2018 , 150 , 876-899.
D. Hertz, M. N. Leiske, T. Wloka, A. Traeger, M. Hartlieb, M. M. Kessels, S. Schubert, B. Qualmann, U. S. Schubert, "Comparison of random and gradient amino functionalized poly(2-oxazoline)s: Can the transfection efficiency be tuned by the macromolecular structure?Externer Link ", J. Polym. Sci., Part A: Polym. Chem. 2018 , DOI: 10.1002/pola.29000.
M. N. Leiske, F. H. Sobotta, F. Richter, S. Hoeppener, J. C. Brendel, A. Traeger, U. S. Schubert, "How to tune the gene delivery and biocompatibility of poly(2-(4-aminobutyl)-2-oxazoline) by self- and coassemblyExterner Link ", Biomacromolecules 2018 , 19 , 748-760.
I. Muljajew, C. Weber, I. Nischang, U. Schubert, "PMMA-g-OEtOx graft copolymers: Influence of grafting degree and side chain length on the conformation in aqueous solutionExterner Link ", Materials 2018 , 11 , 528.
M. Reifarth, S. Hoeppener, U. S. Schubert, "Uptake and intracellular fate of engineered nanoparticles in mammalian cells: Capabilities and limitations of transmission electron microscopypolymerbased nanoparticlesExterner Link ", Adv. Mater. 2018 , 30 , 1703704.
W. S. Zhang, X. Q. Yu, Y. Li, Z. Q. Su, K. D. Jandt, G. Wei, "Protein-mimetic peptide nanofibers: Motif design, self-assembly synthesis, and sequence-specific biomedical applicationsExterner Link ", Prog. Polym. Sci. 2018 , 80 , 94-124.
M. Reifarth, U. S. Schubert, S. Hoeppener, "Considerations for the uptake characteristic of inorgainc nanoparticles into mammalian cells - Insights gained by TEM investigationsExterner Link ", Adv. Biosys. 2018 , DOI: 10.1002/adbi.201700254.
M. Sahn, L. M. Stafast, M. Dirauf, D. Bandelli, C. Weber, U. S. Schubert, "LCST behavior of poly(2-ethyl-2-oxazoline) containing diblock and triblock copolymersExterner Link ", Eur. Polym. J. 2018 , 100 , 57-66.
F. H. Sobotta, F. Hausig, D. O. Harz, S. Hoeppener, U. S. Schubert, J. C. Brendel, "Oxidation-responsive micelles by a one-pot polymerization-induced self-assembly approachExterner Link ", Polym. Chem. 2018 , 9 , 1593-1602.
P. Wei, S. Götz, S. Schubert, J. C. Brendel, U. S. Schubert, "Accelerating the acidic degradation of a novel thermoresponsive polymer by host-guest interactionExterner Link ", Polym. Chem. 2018 , 9 , 2634-2642.
A.-K. Trützschler, T. Bus, M. Reifarth, J. C. Brendel, S. Hoeppener, A. Traeger, U. S. Schubert, "Beyond gene transfection with methacrylate-based polyplexesthe influence of the amino substitution patternExterner Link ", Bioconjugate Chem. 2018 , 29 , 2181-2194.
A. Koeberle, O. Werz, "Natural products as inhibitors of prostaglandin E2 and pro-inflammatory 5-lipoxygenase-derived lipid mediator biosynthesisExterner Link ", Biotechnol. Adv. 2018 , 36 , 1709-1723.
L. Volkmann, M. Köhler, F. H. Sobotta, M. T. Enke, J. C. Brendel, F. H. Schacher, "Poly(2-acrylamidoglycolic acid) (PAGA): Controlled polymerization using RAFT and chelation of metal cationsExterner Link ", Macromolecules 2018 , DOI: 10.1021/acs.macromol.1028b01260.
J. Zhang, B. Farias-Mancilla, M. Destarac, U. S. Schubert, D. J. Keddie, C. Guerrero-Sanchez, S. Harrisson, "Asymmetric copolymers: Synthesis, properties, and applications of gradient and other partially segregated copolymersExterner Link ", Macromol. Rapid Commun. 2018 , 39 , 1800357.
S. Miwa, R. Takahashi, C. Rössel, S. Matsumoto, S. Fujii, J. H. Lee, F. H. Schacher, K. SakuraiCore–shell–corona micelles from a polyether-based triblock terpolymer: Investigation of the pH-dependent micellar structureExterner Link Langmuir 2018 , 34 , 7813-7820.
C. Guerrero‐Sanchez, J. Zhang, J. Vitz, U. S. SchubertHigh-throughput synthesis of polymersExterner Link in Encyclopedia of Polymer Science and Technology , 2018 , doi:10.1002/0471440264.pst0471440668.
2017
A. T. Press, A. Ramoji, M. vd Lühe, A. C. Rinkenauer, J. Hoff, M. Butans, C. Rössel, C. Pietsch, U. Neugebauer, F. H. Schacher, M. BauerCargocarrier interactions significantly contribute to micellar conformation and biodistributionExterner Link NPG Asia Materials 2017 , 9 , e444.
M. Pröhl, S. Seupel, P. Sungur, S. Höppener, M. Gottschaldt, J. C. Brendel, U. S. SchubertThe influence of the grafting density of glycopolymers on the lectin binding affinity of block copolymer micellesExterner Link Polymer 2017 , 133 , 205-212.
I. Perevyazko, A. S. Gubarev, L. Tauhardt, A. Dobrodumov, G. M. Pavlov, U. S. SchubertLinear poly(ethylene imine)s: true molar masses, solution properties and conformationExterner Link Polym. Chem. 2017 , 8 , 7169-7179.
R. Heintzmann, T. HuserSuper-resolution structured illumination microscopyExterner Link Chem. Rev. 2017 , 117 , 13890-13908.