Publikationen

2019 Inhalt einblenden
  1. Gerstmeier, C. Kretzer, S. Di Micco, L. Miek, H. Butschek, V. Cantone, R. Bilancia, R. Rizza, F. Troisi, N. Cardullo, C. Tringali, A. Ialenti, A. Rossi, G. Bifulco, O. Werz, S. Pace,
    Novel benzoxanthene lignans that favorably modulate lipid mediator biosynthesis: A promising pharmacological strategy for anti-inflammatory therapy
    Biochem. Pharmacol. 2019, 165, 263-274.
  2. Gerstmeier, J. Seegers, F. Witt, B. Waltenberger, V. Temml, J. M. Rollinger, H. Stuppner, A. Koeberle, D. Schuster, O. Werz,
    Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis
    Frontiers in Pharmacology 2019, 10.
  3. Shekfeh, B. Çalışkan, K. Fischer, T. Yalçın, U. Garscha, O. Werz, E. Banoglu,
    A Multi‐step Virtual Screening Protocol for the Identification of Novel Non‐acidic Microsomal Prostaglandin E2 Synthase‐1 (mPGES‐1) Inhibitors
    ChemMedChem 2019, 14, 273-281.
  4. Wallert, J. Bauer, S. Kluge, L. Schmölz, Y.-C. Chen, M. Ziegler, A. K. Searle, A. Maxones, M. Schubert, M. Thürmer, H. Pein, A. Koeberle, O. Werz, M. Birringer, K. Peter, S. Lorkowski,
    The vitamin E derivative garcinoic acid from Garcinia kola nut seeds attenuates the inflammatory response
    Redox Biology 2019, 24, 101166.
  5. M. Reifarth, W. Müller, B. Shkodra-Pula, H. Görls, U. S. Schubert, R. Heintzmann, S. Hoeppener,
    "Electron density of polymeric nanoparticles determined by image processing of transmission electron micrographs: Insights into heavy metal staining processes",
    Particle & Particle Systems Characterization 2019, 1800324.
  6. M. Sahn, C. Weber, U. S. Schubert,
    "Poly(2-oxazoline)-containing triblock copolymers: Synthesis and applications",
    Polym. Rev. 2019, doi: 10.1080/15583724.2018.1496930.

  7. P. Wei, G. Gangapurwala, D. Pretzel, M. N. Leiske, L. Wang, S. Hoeppener, S. Schubert, J. C. Brendel, U. S. Schubert,
    "Smart pH-sensitive nanogels for controlled release in an acidic environment",
    Biomacromolecules 2019, 20, 130-140.

  8. M. Werner, P. M. Jordan, E. Romp, A. Czapka, Z. Rao, C. Kretzer, A. Koeberle, U. Garscha, S. Pace, H.-E. Claesson, C. N. Serhan, O. Werz, J. Gerstmeier,
    "Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome",
    The FASEB Journal 2019, doi: 10.1096/fj.201802509R.

  9. L. Wondraczek, G. Pohnert, F. H. Schacher, A. Köhler, M. Gottschaldt, U. S. Schubert, K. Küsel, A. A. Brakhage,
    "Artificial microbial arenas: Materials for observing and manipulating microbial consortia",
    Adv. Mater. 2019, 31, 1900284.

  10. B. Shkodra-Pula, C. Grune, A. Traeger, A. Vollrath, S. Schubert, D. Fischer, U. S. Schubert,
    "Effect of surfactant on the size and stability of PLGA nanoparticles encapsulating a protein kinase C inhibitor",
    Int. J. Pharm. 2019, 566, 756-764.

  11. C. Reichardt, S. Monro, F. H. Sobotta, K. L. Colón, T. Sainuddin, M. Stephenson, E. Sampson, J. Roque, H. Yin, J. C. Brendel, C. G. Cameron, S. McFarland, B. Dietzek,
    "Predictive strength of photophysical measurements for in vitro photobiological activity in a series of Ru(II) polypyridyl complexes derived from π-extended ligands",
    Inorg. Chem. 2019, 58, 3156-3166.

  12. H. Qiu, Z. Yang, M. Köhler, J. Ling, F. H. Schacher,
    "Synthesis and solution self-assembly of poly(1,3-dioxolane)",
    Macromolecules 2019, 52, 3359-3366.

  13. N. Engel, M. Dirauf, S. Seupel, M. N. Leiske, S. Schubert, U. S. Schubert,
    "Utilization of 4-(trifluoromethyl)benzenesulfonates as counter ions tunes the initiator efficiency of sophisticated initiators for the preparation of well-defined poly(2-oxazoline)s",
    Macromol. Rapid Commun. 2019, 40, 1900094.

  14. N. Al Nakeeb, I. Nischang, B. V. K. J. Schmidt,
    "Tannic acid-mediated aggregate stabilization of poly(N-vinylpyrrolidone)-b-poly(oligo (ethylene glycol) methyl ether methacrylate) double hydrophilic block copolymers",
    Nanomaterials 2019, 9, 662.

2018 Inhalt einblenden
  1. C. Englert, J. C. Brendel, T. C. Majdanski, T. Yildirim, S. Schubert, M. Gottschaldt, N. Windhab, U. S. Schubert,
    "Pharmapolymers in the 21st Century: Synthetic Polymers in Drug Delivery Applications",
    Prog. Polym. Sci. 2018, DOI: 10.1016/j.progpolymsci.2018.1007.1005.

  2. P. Dasari, I. A. Shopova, M. Stroe, D. Wartenberg, H. Martin-Dahse, N. Beyersdorf, P. Hortschansky, S. Dietrich, Z. Cseresnyés, M. T. Figge, M. Westermann, C. Skerka, A. A. Brakhage, P. F. Zipfel,
    "Aspf2 from Aspergillus fumigatus recruits human immune regulators for immune evasion and cell damage",
    Front. Immunol. 2018, 9, 1635.

  3. S. Shekfeh, B. Çalışkan, K. Fischer, T. Yalçın, U. Garscha, O. Werz, E. Banoglu,
    "A multi-step virtual screening protocol for the identification of novel non-acidic microsomal prostaglandinE2 synthase-1 (mPGES-1) inhibitors",
    ChemMedChem, 2018, DOI: 10.1002/cmdc.201800701.

  4. L. Vieider, E. Romp, V. Temml, J. Fischer, C. Kretzer, M. Schoenthaler, A. Taha, V. Hernández-Olmos, S. Sturm, D. Schuster, O. Werz, U. Garscha, B. Matuszczak,
    "Synthesis, biological evaluation and structureactivity relationships of diflapolin analogues as dual sEH/FLAP inhibitors",
    ACS Med. Chem. Lett. 2018, DOI: 10.1021/acsmedchemlett.8b00415.

  5. M. Brunzel, T. Majdanski, J. Vitz, I. Nischang, U. Schubert,
    "Fast screening of diol impurities in methoxy poly(ethylene glycol)s (mPEG)s by liquid chromatography on monolithic silica rods",
    Polymers 2018, 10, 1395.

  6. T. C. Majdanski, J. Vitz, A. Meier, M. Brunzel, S. Schubert, I. Nischang, U. S. Schubert,
    "Green ethers as solvent alternatives for anionic ring-opening polymerizations of ethylene oxide (EO): In-situ kinetic and advanced characterization studies",
    Polymer 2018, 159, 86-94.

  7. M. Dirauf, D. Bandelli, C. Weber, H. Görls, M. Gottschaldt, U. S. Schubert,
    "TBD-catalyzed ring-opening polymerization of alkyl-substituted morpholine-2,5-dione derivatives",
    Macromol. Rapid Commun. 2018, 39, 1800433.

  8. A. Sierra-Fernandez, S. C. De la Rosa-García, R. Yañez-Macías, C. Guerrero-Sanchez, L. S. Gomez-Villalba, S. Gómez-Cornelio, M. E. Rabanal, U. S. Schubert, R. Fort, P. Quintana,
    "Solgel synthesis of Mg(OH)2 and Ca(OH)2 nanoparticles: a comparative study of their antifungal activity in partially quaternized p(DMAEMA) nanocomposite films",
    J. Sol-Gel Sci. Technol. 2018, DOI: 10.1007/s10971-10018-14890-10979.

  9. H. Pein, A. Ville, S. Pace, V. Temml, U. Garscha, M. Raasch, K. Alsabil, G. Viault, C.-P. Dinh, D. Guilet, F. Troisi, K. Neukirch, S. König, R. Bilancia, B. Waltenberger, H. Stuppner, M. Wallert, S. Lorkowski, C. Weinigel, S. Rummler, M. Birringer, F. Roviezzo, L. Sautebin, J.-J. Helesbeux, D. Séraphin, A. Mosig, D. Schuster, A. Rossi, P. Richomme, O. Werz, A. Koeberle,
    "Endogenous metabolites of vitamin E limit inflammation by targeting 5 lipoxygenase", 
    Nat. Commun. 2018, 9, 3834.

  10. H. Würfel, M. Kayser, T. Heinze,
    "Efficient and catalyst-free synthesis of cellulose acetoacetates",
    Cellulose 2018, 25, 4919-4928.

  11. K. Ganske, T. Heinze,
    "Evaluation of the synthesis of soluble aromatic cellulose carbonates of low degree of substitution",
    Macromol. Chem. Phys. 2018, 219, 1800152.

  12. T. Bus, A. Traeger, U. S. Schubert,
    "The great escape: how cationic polyplexes overcome the endosomal barrier",
    J. Mater. Chem. B 2018, 6, 6904-6918.

  13. M. Bauer, L. Tauhardt, H. M. L. Lambermont-Thijs, K. Kempe, R. Hoogenboom, U. S. Schubert, D. Fischer,
    "Rethinking the impact of the protonable amine density on cationic polymers for gene delivery: A comparative study of partially hydrolyzed poly(2-ethyl-2-oxazoline)s and linear poly(ethylene imine)s",
    Eur. J. Pharm. Biopharm.
    2018, 133, 112-121.

  14. J. F. Herrmann, C. Höppener,
    "Dumbbell gold nanoparticle dimer antennas with advanced optical properties",
    Beilst. J. Nanotechnol. 2018, 9, 2188-2197.

  15. R. Meyer, X. Yao, V. Deckert,
    "Latest instrumental developments and bioanalytical applications in tip-enhanced Raman spectroscopy",
    Trends Anal. Chem. 2018, 102, 250-258.

  16. D. Bandelli, C. Helbing, C. Weber, M. Seifert, I. Muljajew, K. D. Jandt, U. S. Schubert,
    "Maintaining the hydrophilichydrophobic balance of polyesters with adjustable crystallinity for tailor-made nanoparticles",
    Macromolecules 2018, 51, 5567-5576.

  17. S.-Y. Cheung, M. Werner, L. Esposito, F. Troisi, V. Cantone, S. Liening, S. König, J. Gerstmeier, A. Koeberle, R. Bilancia, R. Rizza, A. Rossi, F. Roviezzo, V. Temml, D. Schuster, H. Stuppner, M. Schubert-Zsilavecz, O. Werz, T. Hanke, S. Pace,
    "Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation",
    Eur. J. Med. Chem. 2018, 156, 815-830.

  18. A. Koeberle, A. Henkel, M. Verhoff, L. Tausch, S. König, D. Fischer, N. Kather, S. Seitz, M. Paul, J. Jauch, O. Werz,
    "Triterpene acids from Frankincense and semi-synthetic derivatives that inhibit 5-lipoxygenase and cathepsin G",
    Molecules 2018, 23, 506.

  19. A.-K. Trützschler, T. Bus, M. Sahn, A. Traeger, C. Weber, U. S. Schubert,
    "The power of shielding: Low toxicity and high transfection performance of cationic graft copolymers containing poly(2-oxazoline) side chains",
    Biomacromolecules 2018, 19, 2759-2771.

  20. M. Grube, M. N. Leiske, U. S. Schubert, I. Nischang,
    "POx as an alternative to PEG? A hydrodynamic and light scattering study",
    Macromolecules 2018, 51, 1905-1916.

  21. Z. T. Gür, B. Çalışkan, U. Garscha, A. Olgaç, U. S. Schubert, J. Gerstmeier, O. Werz, E. Banoglu,
    "Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7",
    Eur. J. Med. Chem. 2018, 150, 876-899.

  22. D. Hertz, M. N. Leiske, T. Wloka, A. Traeger, M. Hartlieb, M. M. Kessels, S. Schubert, B. Qualmann, U. S. Schubert,
    "Comparison of random and gradient amino functionalized poly(2-oxazoline)s: Can the transfection efficiency be tuned by the macromolecular structure?",
    J. Polym. Sci., Part A: Polym. Chem. 2018, DOI: 10.1002/pola.29000.

  23. M. N. Leiske, F. H. Sobotta, F. Richter, S. Hoeppener, J. C. Brendel, A. Traeger, U. S. Schubert,
    "How to tune the gene delivery and biocompatibility of poly(2-(4-aminobutyl)-2-oxazoline) by self- and coassembly",
    Biomacromolecules 2018, 19, 748-760.

  24. I. Muljajew, C. Weber, I. Nischang, U. Schubert,
    "PMMA-g-OEtOx graft copolymers: Influence of grafting degree and side chain length on the conformation in aqueous solution",
    Materials 2018, 11, 528.

  25. M. Reifarth, S. Hoeppener, U. S. Schubert,
    "Uptake and intracellular fate of engineered nanoparticles in mammalian cells: Capabilities and limitations of transmission electron microscopypolymerbased nanoparticles",
    Adv. Mater. 2018, 30, 1703704.

  26. W. S. Zhang, X. Q. Yu, Y. Li, Z. Q. Su, K. D. Jandt, G. Wei,
    "Protein-mimetic peptide nanofibers: Motif design, self-assembly synthesis, and sequence-specific biomedical applications",
    Prog. Polym. Sci. 2018, 80, 94-124.

  27. M. Reifarth, U. S. Schubert, S. Hoeppener,
    "Considerations for the uptake characteristic of inorgainc nanoparticles into mammalian cells - Insights gained by TEM investigations",
    Adv. Biosys. 2018, DOI: 10.1002/adbi.201700254.

  28. M. Sahn, L. M. Stafast, M. Dirauf, D. Bandelli, C. Weber, U. S. Schubert,
    "LCST behavior of poly(2-ethyl-2-oxazoline) containing diblock and triblock copolymers",
    Eur. Polym. J. 2018, 100, 57-66.

  29. F. H. Sobotta, F. Hausig, D. O. Harz, S. Hoeppener, U. S. Schubert, J. C. Brendel,
    "Oxidation-responsive micelles by a one-pot polymerization-induced self-assembly approach",
    Polym. Chem. 2018, 9, 1593-1602.

  30. P. Wei, S. Götz, S. Schubert, J. C. Brendel, U. S. Schubert,
    "Accelerating the acidic degradation of a novel thermoresponsive polymer by host-guest interaction",
    Polym. Chem.
    2018, 9, 2634-2642.

  31. A.-K. Trützschler, T. Bus, M. Reifarth, J. C. Brendel, S. Hoeppener, A. Traeger, U. S. Schubert,
    "Beyond gene transfection with methacrylate-based polyplexesthe influence of the amino substitution pattern",
    Bioconjugate Chem. 2018, 29, 2181-2194.

  32. A. Koeberle, O. Werz,
    "Natural products as inhibitors of prostaglandin E2 and pro-inflammatory 5-lipoxygenase-derived lipid mediator biosynthesis",
    Biotechnol. Adv. 2018, 36, 1709-1723.

  33. L. Volkmann, M. Köhler, F. H. Sobotta, M. T. Enke, J. C. Brendel, F. H. Schacher,
    "Poly(2-acrylamidoglycolic acid) (PAGA): Controlled polymerization using RAFT and chelation of metal cations",
    Macromolecules 2018, DOI: 10.1021/acs.macromol.1028b01260.

2017 Inhalt einblenden
  1. A. T. Press, A. Ramoji, M. vd Lühe, A. C. Rinkenauer, J. Hoff, M. Butans, C. Rössel, C. Pietsch, U. Neugebauer, F. H. Schacher, M. Bauer, "Cargocarrier interactions significantly contribute to micellar conformation and biodistribution", NPG Asia Materials 2017, 9, e444.

  2. M. Pröhl, S. Seupel, P. Sungur, S. Höppener, M. Gottschaldt, J. C. Brendel, U. S. Schubert, "The influence of the grafting density of glycopolymers on the lectin binding affinity of block copolymer micelles", Polymer 2017, 133, 205-212.
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