Publications

A woman in a library

2025
M. Streiber, N. E. Göppert, V. Bachmann, B. Schulze, R. Gläßer, I. Anufriev, P. Schädel, I. Nischang, C. Weber, O. Werz, U. S. Schubert, A. Traeger
Tailoring cationic poly(2-oxazoline)s: Minimizing toxicity and immunogenic response for biological applicationsExternal link
Mater. Today Chem. 2025, 44, 102549.

I. Anufriev, T. Klein, S. Hoeppener, J. C. Brendel, I. Nischang
Supramolecular polymer bottlebrushes: In situ assessment of noncovalent assemblies in human serum by analytical ultracentrifugation External link
Macromol. Rapid Commun. 2025, 46, 2400890.

V. H. P. Carrillo, J. J. Whittaker, C. Wiedemann, J. M. Harder, T. Lohr, A. K. Jamithireddy, M. Dajka, B. Goretzki, B. Joseph, A. Guskov, N. J. Harmer, U. Holzgrabe, U. A. Hellmich
Structure and dynamics of macrophage infectivity potentiator proteins from pathogenic bacteria and protozoans bound to fluorinated pipecolic acid inhibitorsExternal link
J. Med. Chem. 2025, 68, 5926-5941.

Y. F. Chen, F. Arendt, H. Bornhoeft, A. S. S. de Camargo, J. Deubener, A. Diegeler, S. Gogula, A. T. C. Jaimes, S. Kempf, M. Kilo, R. Limbach, R. Mueller, R. Niebergall, Z. W. Pan, F. Puppe, S. Reinsch, G. Schottner, S. Stier, T. Waurischk, L. Wondraczek, M. Sierka
Ontology-based digital infrastructure for data-driven glass developmentExternal link
Adv. Eng. Mat. 2025, 27, 2401560.

E. Colarusso, G. Lauro, M. Potenza, P. Galatello, M. L. D. Garigliota, M. G. Ferraro, M. Piccolo, M. G. Chini, C. Irace, P. Campiglia, R. K. Hoffstetter, O. Werz, A. Ramunno, G. Bifulco
5-methyl-2-carboxamidepyrrole-based novel dual mPGES-1/sEH inhibitors as promising anticancer candidatesExternal link
Arch. Pharm. (Weinheim) 2025, 358, e2400708.

A. Fruntke, J. Hulsmann, L. H. Skodda, B. Blumbott, M. Godmann, A. Koschella, T. Heinzel, T. Heinze, T. Wilke
Polysaccharide-based nanoparticles prepared by dialysis: Novel drug deliveryExternal link
J. Chem. Educ. 2025, 102, 1169-1178.

E. Gardey, J. C. Brendel, A. Stallmach
Pathophysiology of IBD as a key strategy for polymeric nanoparticle development External link
Adv. Therap. 2025, 8, 2400439.

S. Greiner, M. Ebrahimi, M. Rodewald, A. Urbanek, T. Meyer-Zedler, M. Schmitt, U. Neugebauer, J. Popp
Characterizing metabolic shifts in septic murine kidney tissue using 2P-FLIM for early sepsis detection External link
Bioengineering 2025, 12, 170.

H. Koceva, M. Amiratashani, P. Akbarimoghaddam, B. Hoffmann, G. Zhurgenbayeva, M. S. Gresnigt, V. R. Marcelino, C. Eggeling, M. T. Figge, M. J. Amorim, A. S. Mosig
Deciphering respiratory viral infections by harnessing organ-on-chip technology to explore the gut-lung axisExternal link
Open. Biol. 2025, 15, 240231.

L. S. Reichel, A. Kemmer, T. Heinze, A. Traeger
Design of pH-responsive and amphiphilic pullulan-based biological macromolecule for gene deliveryExternal link
Int. J. Biol. Macromol. 2025, 301, 140014.

L. Xiong, D. Beyer, N. Liu, T. Lehmann, S. Neugebauer, S. Schaeuble, O. Sommerfeld, P. Ernst, C. M. Svensson, S. Nietzsche, S. Scholl, T. Bruns, N. Gassler, M. H. Gräler, M. T. Figge, G. Panagiotou, M. Bauer, A. T. Press
Targeting protein kinase C-α prolongs survival and restores liver function in sepsis: Evidence from preclinical modelsExternal link
Pharmacol. Res. 2025, 212, 107581.

T. Yalçin, P. M. Jordan, A. Olgaç, P. Dahlke, T. G. Maz, E. Banoglu, O. Werz, B. Çaliskan
2-Phenylbenzothiazoles featuring heteroaryl sulfonamide end-capping substructures as developable mPGES-1 inhibitorsExternal link
Arch. Pharm. 2025, 358, e2400756.

J. Schroeder, J. Westhoff, I. Vilotijević, O. Werz, S. Hoeppener, B. Löffler, D. Fischer, C. Ehrhardt
Anti-influenza activity of 6BIGOE: Improved pharmacological profile after encapsulation in plga nanoparticles External link
Int. J. Mol. Sci. 2025, 26, 4235.

K. Mehmetaj, W. Foo, Z. Cseresnyés, J. Plitzko, T. A. Shaik, Q. Ain, A. Ramoji, S. Huschke, L. Xiong, A. Zipprich, J. Popp, M. T. Figge, V. Deckert, S. Schubert, N. Gassler, F. H. Schacher, M. Bauer, A. T. Press
Passively targeted polymeric nanocarrier delivering STAT1 siRNA to the liver ameliorates steatohepatitis and fibrosis in the thioacetamide mouse modelExternal link
Biomaterials 2025.

G. Lauro, M. Aliberti, M. De Nisco, S. Pedatella, G. Pepe, M. G. Basilicata, M. G. Chini, K. Fischer, R. K. Hofstetter, O. Werz, M. G. Ferraro, M. Piccolo, C. Irace, A. Saviano, P. Campiglia, A. Bertamino, C. Ostacolo, T. Ciaglia, M. Manfra, G. Bifulco
Furazanopyrazine-based novel promising anticancer agents interfering with the eicosanoid biosynthesis pathways by dual mPGES-1 and sEH inhibitionExternal link
Eur. J. Med. Chem. 2025, 289, 117402.

C. T. Holick, T. Klein, C. Mehnert, F. Adermann, I. Anufriev, M. Streiber, L. Harder, A. Traeger, S. Hoeppener, C. Franke, I. Nischang, S. Schubert, U. S. Schubert
Poly(2-ethyl-2-oxazoline) (POx) as poly(ethylene glycol) (PEG) lipid substitute for lipid nanoparticle formulationsExternal link
Small 2025, 21, 2411354.

S. Bekemeier, C. R. Caldeira Rêgo, H. L. Mai, U. Saikia, O. Waseda, M. Apel, F. Arendt, A. Aschemann, B. Bayerlein, R. Courant, G. Dziwis, F. Fuchs, U. Giese, K. Junghanns, M. Kamal, L. Koschmieder, S. Leineweber, M. Luger, M. Lukas, J. Maas, J. Mertens, B. Mieller, L. Overmeyer, N. Pirch, J. Reimann, S. Schröck, P. Schulze, J. Schuster, A. Seidel, O. Shchyglo, M. Sierka, F. Silze, S. Stier, M. Tegeler, J. F. Unger, M. Weber, T. Hickel, J. Schaarschmidt
Advancing digital transformation in material science: The role of workflows within the MaterialDigital initiativeExternal link
Adv. Eng. Mat. 2025, 27, 2402149.

C. Ventura-Hunter, D. Pretzel, C. Kellner, S. Hoeppener, N. C. Roesner, P. Quintana-Owen, U. S. Schubert, G. Ayora-Talavera, E. Saldívar-Guerra, S. Fedeli, C. Guerrero-Sanchez
Amphiphilic block copolymer conjugated with cell-penetrating-peptides derived from Influenza A H1N1 virus as a biocompatible scaffold for enhanced cell-uptakeExternal link
Eur. Polym. J. 2025, 229, 113876.

M. Kötzsche, J. Egger, A. Dzierza, S. Reichel, I. Nischang, A. Traeger, D. Fischer, K. Peneva
Making the negative positive – fluorination of indole as efficient strategy to improve guanidinium-containing gene carriersExternal link
J. Mater. Chem. B 2025.

S. Zhang, K. Schlabach, V. H. P. Carrillo, A. Ibrahim, A. Komor, R. Mukherji, S. Chowdhury, L. Reimer, F. Trottmann, C. Hertweck, U. A. Hellmich, P. Stallforth
A chemical radar allows bacteria to detect and kill predatorsExternal link
Cell 2025, 118, 2495-2504.e20.

S. Sunoqrot, S. Abusulieh, I. Anufriev, P. Dahlke, P. M. Jordan, E. Al-Shalabi, C. T. Holick, S. Hoeppener, I. Nischang, O. Werz, S. Schubert, U. S. Schubert
Mild oxidation of plant polyphenols yields modular nanoparticle-forming materials with drug loading capabilitiesExternal link
Macromol. Biosci. 2025, 2400529.

A. Wallbraun, T. Wilke
Vom erkrankten Organ zur gezielten Behandlung – Medikamenten-Taxis aus Nano-Kunststoffen im Unterricht untersuchen
Unterricht Chemie 2025, 207, 36-42.

I. Parchmann, H. Rautenstrauch, T. Wilke, P. Wlotzka
Medikamente und ihre Wirkstoffe - ein Thema auch für den Chemieunterricht
Unterricht Chemie 2025, 207, 2-8.

P. Wlotzka, T. Wilke
Wirkstoffeigenschaften optimieren dank Polyethylenglyco l– Struktur-Eigenschaftsbeziehungen von Kunststoffen
Unterricht Chemie 2025, 207, 30-34.

T. Koswig, J. Kimmig, A. Vollrath, A. Träger, S. Zechel, U. S. Schubert
Automatisierung, Robotik und künstliche Intelligenz - Auf dem digitalen Weg zu neuen Medikamenten
Unterricht Chemie 2025, 207, 9-11.

X. Wang, A. Stihl, C. Höppener, J. Vitz, F. H. Schacher, V. Deckert
Nanoscale investigation of elasticity changes and augmented rigidity of block copolymer micelles induced by reversible core-cross-linkingExternal link
ACS Appl. Mater. Int. 2025, 17, 27557-27567.

G. Perçin, K. Riege, J. Fröbel, J. Metz, S. Culemann, M. Lesche, S. Reinhardt, T. Höfer, S. Hoffmann, C. Waskow
Embryonic macrophages orchestrate niche cell homeostasis for the establishment of the definitive hematopoietic stem cell poolExternal link
Nat. Commun. 2025, 16, 4428.

L.-J. Jia, F. A. Bernal, J. Söhnlein, J. Sonnberger, I. Heineking, M. Rafiq, Z. Cseresnyés, F. Kage, F. Schmidt, R. Zaher, P. Hortschansky, S. Chaudhary, X. Gong, J. Schirawski, M. T. Figge, B. Hube, A. A. Brakhage
Convergent evolution of a fungal effector enabling phagosome membrane penetrationExternal link
bioRxiv 2025.
2024
L. M. Stafast, M. Swieczkowski, P. Poudel, N. Engel, C. Yin, K. Scheuer, C. Weber, F. H. Schacher, K. D. Jandt, U. S. Schubert
POxylated stereocomplexes from PEtOx-b-PLA Diblock copolymersExternal link
Eur. Polym. J. 2024, 221, 113545.

Y. Köster, J. Kimmig, S. Zechel, U. S. Schubert
Implementation of the Polymerfingerprint: A molecular structure representation into an artificial neural networkExternal link
STAR Protocols 2024, 5(2), 103055.

I. Lepori, Y. Oz, J. Im, N. Ghosh, M. Paul, U. S. Schubert, S. Fedeli
Bioorthogonal “Click” cycloadditions: A toolkit for modulating polymers and nanostructures in living systemsExternal link
Reactions 2024, 5(1), 231–245.

C. Yin, J. Hemstedt, K. Scheuer, M. Struczyńska, C. Weber, U. S. Schubert, J. Bossert, K. D. Jandt
The effect of stereocomplexation and crystallinity on the degradation of polylactide nanoparticlesExternal link
Nanomater. 2024, 14(5), 440.

M. Behnke, A. Vollrath, P. Dahlke, F. P. Larios, M. Chi, E. Tsarenko, P. M. Jordan, C. Weber, M. Dirauf, J. A. Czaplewska, B. Beringer-Siemers, S. Stumpf, C. Kellner, C. Kretzer, S. Hoeppener, I. Nischang, M. Sierka, C. Eggeling, O. Werz, U. S. Schubert,
PEtOxylated polyesteramide nanoparticles for the delivery of anti-inflammatory drugsExternal link
Mater. Today Chem. 2024, 35, 101848.

P. Zahel, V. Bruggink, J. Hülsmann, F. Steiniger, R. K. Hofstetter, T. Heinzel, U. Beekmann, O. Werz, D. Kralisch
Exploring microemulsion systems for the incorporation of glucocorticoids into bacterial cellulose: A novel approach for anti-inflammatory wound dressingsExternal link
Pharmaceutics, 2024, 16(4), 504.

X. Yao, S. Ehtesabi, C. Höppener, T. Deckert-Gaudig, H. Schneidewind, S. Kupfer, S. Gräfe, V. Deckert
Mechanism of plasmon-induced catalysis of thiolates and the impact of reaction conditionsExternal link
J. Am. Chem. Soc. 2024, 146(5), 3031-3042.

T. Wilke, M. Petersen, A. Fruntke
Wissen aus dem Labor unterrichtsgerecht aufbereitenExternal link
NadC. 2024, 72(2), 8-11.

M. Valentine, P. Rudolph, A. Dietschmann, A. Tsavou, S. Mogavero, S. Lee, E. L. Priest, G. Zhurgenbayeva, N. Jablonowski, S. Timme, C. Eggeling, S. Allert, E. Dolk, J. R. Naglik, M. T. Figge, M. S. Gresnigt, B.Hube
Nanobody-mediated neutralization of candidalysin prevents epithelial damage and inflammatory responses that drive vulvovaginal candidiasis pathogenesisExternal link
MBio. 2024, 15(3), e03409-23.

A.Seltmann, P. Carravilla, K. Reglinski, C. Eggeling, D. Waithe
Neural network informed photon filtering reduces fluorescence correlation spectroscopy artifactsExternal link
Biophys. J. 2024, 123(6), 745-755.

K. K.Schwickert, M. Glitscher, D. Bender, R. Murra, K. Schwickert, S. Pfalzgraf, T. Schirmeister, U. A. Hellmich, E. Hildt
Late stages of the Zika virus life cycle are impaired by a selective TRPML2 agonistExternal link
bioRxiv 2024, 578205.

S. Mikutis, S. Lawrinowitz, C. Kretzer, L. Dunsmore, L. Sketeris, T. Rodrigues, O. Werz, G. J. L. Bernardes
Machine learning uncovers natural product modulators of the 5-lipoxygenase pathway and facilitates the elucidation of their biological mechanismsExternal link
ACS Chem. Biol. 2024, 19(1), 217-229.

P. P. Mapfumo, J. I. Solomun, F. Becker, E. Moek, M. N. Leiske, L. K. Rudolph, J. C. Brendel, A. Traeger
Vitamin B3 containing polymers for nanodeliveryExternal link
Macromol. Biosci. 2024, 24, 2400002.

P. P. Mapfumo, L. S. Reichel, S. Hoeppener, A. Traeger
Improving gene delivery: Synergy between alkyl chain length and lipoic acid for PDMAEMA hydrophobic copolymersExternal link
Macromol. Rapid Commun. 2024, 45(7), 2300649.

P. Manhas, C. Cokca, R. Sharma, K. Peneva, N. Wangoo, D. Sharma, R. K. Sharma
Chitosan functionalized doxorubicin loaded poly(methacrylamide) based copolymeric nanoparticles for enhanced cellular internalization and in vitro anticancer evaluationExternal link
Int. J. Biol. Macromol. 2024, 259, 129242.

K. Leer, L. S. Reichel, M. Wilhelmi, J. C. Brendel, A. Traeger
Tailoring gene transfer efficacy through the arrangement of cationic and anionic blocks in triblock copolymer micellesExternal link
ACS Macro Lett. 2024, 13(2), 158-165.

K. Leer, L. S. Reichel, J. Kimmig, F. Richter, S. Hoeppener, J. C. Brendel, S. Zechel, U. S. Schubert, A. Traeger
Optimization of mixed micelles based on oppositely charged block copolymers by machine learning for application in gene deliveryExternal link
Small 2024, 20(6), 2306116.

K. Kowalczuk, A. Dasgupta, F. Páez Larios, H. F. Ulrich, V. Wegner, J. C. Brendel, C. Eggeling, A. S. Mosig, F. H. Schacher
Self-degrading multifunctional PEG-based hydrogels—Tailormade substrates for cell cultureExternal link
Macromol. Biosci. 2024, 24(5), 2300383.

S. König, J. Schroeder, S. Nietzsche, T. Heinekamp, A. A. Brakhage, R. Zell, B. Löffler, C. Ehrhardt
The influenza A virus promotes fungal growth of Aspergillus fumigatus via direct interaction in vitroExternal link
Microbes Infect. 2024, 26(3), 105264.

J. Joseph, L. Spantzel, M. Ali, J. D. Moonnukandathil , S. Unger, K. Reglinski, C. Krafft, A.-D. Müller, C. Eggeling, R. Heintzmann, M. Börsch, A. T. Press, D. Täuber
Nanoscale chemical characterization of secondary protein structure of F-Actin using mid-infrared photoinduced force microscopy (PiF-IR)External link
Spectrochim Acta. A. Mol. Biomol. Spectrosc. 2024, 306, 123612.

P. M. Jordan, K. Günther, V. Nischang, Y. Ning, S. Deinhardt-Emmer, C. Ehrhardt, O. Werz
Influenza A virus selectively elevates prostaglandin E(2) formation in pro-resolving macrophagesExternal link
Iscience 2024, 27(1), 108775.

J. Ismail, L. C. Klepsch, P. Dahlke, E. Tsarenko, A. Vollrath, D. Pretzel, P. M. Jordan, K. Rezaei, J. A. Czaplewska, S. Stumpf, B. Beringer-Siemers, I. Nischang, S. Hoeppener, O. Werz, U. S. Schubert
PEG-Lipid-PLGA hybrid particles for targeted delivery of anti-inflammatory drugsExternal link
Pharmaceutics 2024, 16(2), 187.

E. Gardey, Z. Cseresnyes, F. H. Sobotta, J. Eberhardt, D. Haziri, P. C. Grunert, M. T. Kuchenbrod, F. V. Gruschwitz, S. Hoeppener, M. Schumann, N. Gaßler, M. T. Figge, A. Stallmach, J. C. Brendel
Selective uptake into inflamed human intestinal tissue and immune cell targeting by wormlike polymer micellesExternal link
Small 2024, 20 (21), e2306482.

B. Farias-Mancilla, A. Balestri, J. Zhang, H. Frielinghaus, D. Berti, C. Montis, M. Destarac, U. S. Schubert, C. Guerrero-Sanchez, S. Harrisson, B. Lonetti
Morphology and thermal transitions of self-assembled NIPAM-DMA copolymers in aqueous media depend on copolymer composition profileExternal link
J. Colloid Interface Sci. 2024, 662, 99-108.

C. Ehle, A. Iyer-Bierhoff, Y. Wu, S. Xing, M. Kiehntopf, A. S. Mosig, M. Godmann, T. Heinzel
Downregulation of HNF4A enables transcriptomic reprogramming during the hepatic acute-phase responseExternal link
Commun. Biol. 2024, 7(1), 589.

C. Cerchia, L. Küfner, O. Werz, A. Lavecchia
Identification of selective 5-LOX and FLAP inhibitors as novel anti-inflammatory agents by ligand-based virtual screeningExternal link
Eur. J. Med. Chem. 2024, 263, 115932.

M. Behnke, C. T. Holick, A. Vollrath, S. Schubert, U. S. Schubert
Knowledge-based design of multifunctional polymeric nanoparticlesExternal link
Handb. Exp. Pharmacol. 2024, 284, 3-26.

J. De Breuck, M. Streiber, M. Ringleb, D. Schröder, N. Herzog, U. S. Schubert, S. Zechel, A. Traeger, M. N. Leiske
Amino-acid-derived anionic polyacrylamides with tailored hydrophobicity–physicochemical properties and cellular interactionsExternal link
ACS Polym. 2024, 4(3), 222–234.

R. Kampes, A. Chettri, M. Sittig, G. Yang, S. Zechel, S. Kupfer, M. D. Hager, B. Dietzek-Ivanšić, U. S. Schubert
An iridium complex as bidentate halogen bond-based anion receptor featuring an increased optical responseExternal link
Chem. Open 2024, 13, e202300183.

R. Pérez-Isidoro, A. G. Valdez-Lara, A. J. Díaz-Salazar, S. Hoeppener, C. Guerrero-Sánchez, P. Quintana-Owen, J. C. Ruiz-Suárez, U. S. Schubert, G. Ayora-Talavera, M. A. De Jesús-Téllez, E. Saldívar-Guerra
Biophysical investigation of liposome systems decorated with bioconjugated copolymers in the presence of amantadineExternal link
J. Mater. Chem. B 2024, 12, 5823–5837.

T. Schuett, P. Endres, J. Kimmig, R. Lorenz, Y. Köster, S. Stumpf, S. Zechel, U. S. Schubert
Automated screening of precipitation polymerizations and evaluation using image recognition for divinylbenzene and methacrylic acidExternal link
J. Appl. Polym. Sci. 2024, 141 (38), e55985.

L. Simon, L. S. Reichel, B. T. Benkhaled, J.-M. Devoisselle, S. Catrouillet, J. Eberhardt, S. Hoeppener, U. S. Schubert, J. C. Brendel, M. Morille, V. Lapinte, A. Traeger
Polyoxazolines with cholesterol lipid anchor for fast intracellular deliveryExternal link
Macromol. Biosci. 2024, 24, 2400148.

J. Alex, C. Weber, C. Guerrero-Sanchez, U. S. Schubert
Recent developments in synthetic approaches for macromolecular prodrugsExternal link
Progr. Polym. Sci. 2024, 155, 101855.

E. Tsarenko, N. E. Goeppert, P. Dahlke, M. Behnke, G. Gangapurwala, B. Beringer-Siemers, L. Jaepel, C. Kellner, D. Pretzel, J. A. Czaplewska, A. Vollrath, P. M. Jordan, C. Weber, O. Werz, U. S. Schubert, I. Nischang
Unveiling the power of liquid chromatography in examining a library of degradable poly(2-oxazoline)s in nanomedicine applicationsExternal link
J. Mater. Chem. B 2024, 12, 11926-11938.

R. Alonso-Roman, A. S. Mosig, M. T. Figge, K. Papenfort, C. Eggeling, F. H. Schacher, B. Hube, M. S. Gresnigt
Organ-on-chip models for infectious disease researchExternal link
Nat. Microbiol 2024, 9, 891-904.

I. Anufriev, J. Debbeler, A. Traeger, I. Nischang
Analysis of Macromolecular Systems as Enabler for Energy and Life Science ApplicationsExternal link
Macromol. Chem. Phys. 2024, 225, 17.

V. Bachmann, P. Schädel, J. Westhoff, M. Peric, F. Schömberg, A. L. Skaltsounis, S. Höppener, T. Pantsar, D. Fischer, I. Vilotijevic, O. Werzae
Bromo-substituted indirubins for inhibition of protein kinase-mediated signalling involved in inflammatory mediator release in human monocyteExternal links
Bioorg. Chem. 2024, 149, 107470.

A. Chettri, L. I. Kaberov, N. Klosterhalfen, S. Perera, M. Jamshied, F. H. Schacher, B. Dietzek-Ivansic
Poly(2-Oxazoline) amphiphilicity tunes the excited-state proton transfer of pyrenol-based polyphotoacids External links
Chem. Eur. J. 2024, 30, e202401047.

A. Dasgupta, A. Koerfer, B. Kokot, I. Urbancic, C. Eggeling, P. Carravilla
Effects and avoidance of photoconversion-induced artifacts in confocal and STED microscopyExternal link
Nat. Methods 2024, 21, 1171–1174.

A. Feile, V. D. Wegner, M. Raasch, A. S. Mosig
Immunocompetent intestine-on-chip model for analyzing gut mucosal immune responses External link
J. Vis. Exp. 2024, 207, e66603.

E. Gardey, J. Eberhardt, S. Hoeppener, F. H. Sobotta, J. C. Brendel, A. Stallmach
Anti-inflammatory potential of beclometasone-loaded filomicelles on activated human monocytes External link
Macromol. Biosci. 2024, 24, 2400179.

A. P. Grimm, M. Plank, A. Stihl, C. W. Schmitt, D. Voll, F. H. Schacher, J. Lahann, P. Théato
Inverse vulcanization of activated norbornenyl esters-a versatile platform for functional sulfur polymers External link
Angew. Chem. Int. Ed. 2024, 63, e202411010.

K. Günther, C. Ehrhardt, O. Werz, P. M. Jordan
Protocol for lipid mediator profiling and phenotyping of human M1- and M2-monocyte-derived macrophages during host-pathogen interactionsExternal link
STAR Protoc. 2024, 5(3), 103142.

C. Höppener, J. Aizpurua, H. Chen, S. Gräfe, A. Jorio, S. Kupfer, Z. L. Zhang, V. Deckert
Tip-enhanced Raman scatteringExternal link
Nat. Rev. Method. Prim. 2024, 4, 47.

L. J. Jia, K. González, T. Orasch, F. Schmidt, A. A. Brakhage
Manipulation of host phagocytosis by fungal pathogens and therapeutic opportunitiesExternal link
Nat. Microbiol 2024, 9, 2216-2231.

R. Kampes, A. Chettri, M. Sittig, G. J. Yang, S. Zechel, S. Kupfer, M. D. Hager, B. Dietzek-Ivansic, U. S. Schubert
An iridium complex as bidentate halogen bond-based anion receptor featuring an increasedoptical response External link
ChemistryOpen 2024, 13, e202300183.

Y. Köster, J. Kimmig, S. Zechel, U. S. Schubert
Protocol for creating representations of molecular structures using a polymer-specific decoderExternal link
STAR Protoc. 2024, 5(2), 103055.

S. Kröller, J. Schober, N. Krieg, S. Dennhardt, W. Pirschel, M. Kiehntopf, E. M. Conway, S. M. Coldewey
The role of the n-terminal domain of thrombomodulin and the potential of recombinant human thrombomodulin as a therapeutic intervention for shiga toxin-induced hemolytic-uremic syndromeExternal link
Toxins 2024, 16 (9), 409.

N. Liu, M. Sonawane, O. Sommerfeld, C. M. Svensson, M. T. Figge, R. Bauer, S. J. Bischoff, M. Bauer, M. F. Osuchowski, A. T. Press
Metamizole outperforms meloxicam in sepsis: insights on analgesics, survival and immunomodulation in the peritoneal contamination and infection sepsis modelExternal link
Front. Immunol. 2024, 15, 1432307.

K. Majzner, T. Deckert-Gaudig, M. Baranska, V. Deckert
DOX-DNA interactions on the nanoscale: In situ studies using tip-enhanced raman scatteringExternal link
Anal. Chem. 2024, 96(22), 8905-8913.

P. P. Mapfumo, L. S. Reichel, T. André, S. Hoeppener, L. K. Rudolph, A. Traeger
Optimizing biocompatibility and gene delivery with DMAEA and DMAEAm: A niacin-derived copolymer approach External link
Biomacromolecules 2024, 25 (8), 4749-4761.

P. P. Mapfumo, L. S. Reichel, K. Leer, J. Egger, A. Dzierza, K. Peneva, D. Fischer, A. Traeger
Harnessing guanidinium and imidazole functional groups: A dual-charged polymer strategy for enhanced gene delivery External link
ACS Macro Lett. 2024, 13(8), 1000-1007.

T. G. Maz, P. Dahlke, A. G. Ergül, A. Olgaç, P. M. Jordan, B. Çaliskan, O. Werz, E. Banoglu
Novel 1,3,4-oxadiazole derivatives as highly potent microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitorsExternal link
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H. F. Ulrich, F. V. Gruschwitz, T. Klein, N. Ziegenbalg, D. T. N. Anh, S. Fujii, S. Hoeppener, K. Sakurai, J. C. Brendel
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J. Plitzko, T. Köhler, T. Meyer-Zedler, S. Schubert, M. Schmitt, J. Popp
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N. Engel, M. Dirauf, J. A. Czaplewska, I. Nischang, M. Gottschaldt, U. S. Schubert
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N. t. Horst, J. Dietrich, T. Wilke
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G. De Angelis, J. Abramo, M. Miasnikova, M. Taubert, C. Eggeling, F. Reina
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A. G. Ergul, P. M. Jordan, P. Dahlke, N. B. Bal, A. Olgac, O. Uludag, O. Werz, B. Caliskan, E. Banoglu
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C. Haring, J. Schroeder, J. Jungwirth, B. Loffler, A. Henke, B. Engert, C. Ehrhardt
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L.-J. Jia, M. Rafiq, L. Radosa, P. Hortschansky, C. Cunha, Z. Cseresnyés, T. Krüger, F. Schmidt, T. Heinekamp, M. Straßburger, B. Löffler, T. Doenst, J. F. Lacerda, A. Campos, M. T. Figge, A. Carvalho, O. Kniemeyer, A. A. Brakhage
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F. Borner, S. Pace, P. M. Jordan, J. Gerstmeier, M. Gomez, A. Rossi, N. C. Gilbert, M. E. Newcomer, O. Werz
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M. Behnke, P. Klemm, P. Dahlke, B. Shkodra, B. Beringer-Siemers, J. A. Czaplewska, S. Stumpf, P. M. Jordan, S. Schubert, S. Hoeppener, A. Vollrath, O. Werz, U. S. Schubert
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M. Kühne, S. Hofmann, H. Lindemann, Z. Cseresnyés, A. Dzierza, D. Schröder, M. Godmann, A. Koschella, C. Eggeling, D. Fischer, M. T. Figge, T. Heinze, T. Heinzel
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W. Foo, Z. Cseresnyes, C. Rossel, Y. F. Teng, A. Ramoji, M. Z. Chi, W. Hauswald, S. Huschke, S. Hoeppener, J. Popp, F. H. Schacher, M. Sierka, M. T. Figge, A. T. Press, M. Bauer
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A. T. Frawley, K. G. Leslie, V. Wycisk, S. Galiani, D. Shrestha, C. Eggeling, H. L. Anderson
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A. Fruntke, M. Behnke, L. M. Stafast, T. Trader, E. Dietel, A. Vollrath, C. Weber, U. S. Schubert, T. Wilke
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S. Galiani, C. Eggeling, K. Reglinski
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M. Goldmann, F. Schmidt, Z. Cseresnyes, T. Orasch, S. Jahreis, S. Hartung, M. T. Figge, M. von Lilienfeld-Toal, T. Heinekamp, A. A. Brakhage
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K. Gonzalez, G. Gangapurwala, J. Alex, A. Vollrath, Z. Cseresnyes, C. Weber, J. A. Czaplewska, S. Hoeppener, C. M. Svensson, T. Orasch, T. Heinekamp, C. Guerrero-Sanchez, M. T. Figge, U. S. Schubert, A. A. Brakhage
Targeting of phagolysosomes containing conidia of the fungus Aspergillus fumigatus with polymeric particlesExternal link
Appl. Microbiol. Biotechnol. 2023, 107, 819-834.

F. Hausig-Punke, G. Dekevic, F. H. Sobotta, J. I. Solomun, F. Richter, D. Salzig, A. Traeger, J. C. Brendel
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C. Hoppener, J. K. Elter, F. H. Schacher, V. Deckert
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V. Krauth, F. Bruno, S. Pace, P. M. Jordan, V. Temml, M. P. Romano, H. Khan, D. Schuster, A. Rossi, R. Filosa, O. Werz
Highly potent and selective 5-lipoxygenase inhibition by new, simple heteroaryl-substituted catechols for treatment of inflammationExternal link
Biochem. Pharmacol. 2023, 208, 115385.

V. D. Lechuga-Islas, D. M. Sanchez-Cerrillo, S. Stumpf, R. Guerrero-Santos, U. S. Schubert, C. Guerrero-Sanchez
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V. D. Lechuga-Islas, M. Trejo-Maldonado, I. Anufriev, I. Nischang, I. Terzioglu, J. Ulbrich, R. Guerrero-Santos, L. E. Elizalde-Herrera, U. S. Schubert, C. Guerrero-Sanchez
All-aqueous, surfactant-free, and pH-driven nanoformulation methods of dual-responsive polymer nanoparticles and their potential use as nanocarriers of pH-sensitive drugsExternal link
Macromol. Biosci. 2023, 23, 2200262.

X. Liu, D. Wenisch, P. Dahlke, P. M. Jordan, M. A. Jakupec, C. R. Kowol, P. Liebing, O. Werz, B. K. Keppler, W. Weigand
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F. J. Ma, R. Kaufmann, J. Sedzicki, Z. Cseresnyes, C. Dehio, S. Hoeppener, M. T. Figge, R. Heintzmann
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PLoS One 2023, 18, e0282803.

T. G. Maz, B. Koc, P. M. Jordan, K. Ibis, B. Caliskan, O. Werz, E. Banoglu
Benzoxazolone-5-urea derivatives as human soluble epoxide hydrolase (sEH) inhibitorsExternal link
ACS Omega 2023, 8 (2), 2445-2454.

M. Naumann, N. Arend, R. R. Guliev, C. Kretzer, I. Rubio, O. Werz, U. Neugebauer
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T. Orasch, G. Gangapurwala, A. Vollrath, K. Gonzalez, J. Alex, A. D. Luis, C. Weber, S. Hoeppener, Z. Cseresnyes, M. T. Figge, C. Guerrero-Sanchez, U. S. Schubert, A. A. Brakhage
Polymer-based particles against pathogenic fungi: A non-uptake delivery of compoundsExternal link
Biomater. Adv. 2023, 146, 213300.

R. Perez-Isidoro, F. J. Guevara-Pantoja, C. Ventura-Hunter, C. Guerrero-Sanchez, J. C. Ruiz-Suarez, U. S. Schubert, E. Saldivar-Guerra
Fluidized or not fluidized? Biophysical characterization of biohybrid lipid/protein/polymer liposomes and their interaction with tetracaineExternal link
Biochim. Et Biophys. Acta - General Subjects 2023, 1867 (2), 130287.

M. Potenza, A. Giordano, M. G. Chini, A. Saviano, C. Kretzer, F. Raucci, M. Russo, G. Lauro, S. Terracciano, I. Bruno, M. Iorizzi, R. K. Hofstetter, S. Pace, F. Maione, O. Werz, G. Bifulco
Identification of 2-aminoacyl-1,3,4-thiadiazoles as prostaglandin E2 and leukotriene biosynthesis inhibitorsExternal link
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L. M. Stafast, N. Engel, H. Gorls, C. Weber, U. S. Schubert
End-functionalized diblock copolymers by mix and match of poly (2-oxazoline) and polyester building blocksExternal link
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E. Tsarenko, U. S. Schubert, I. Nischang
Nanoparticle formulation composition analysis by liquid chromatography on reversed-phase monolithic silicaExternal link
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S. Wang, P. Poudel, F. H. Schacher, L. I. Kaberov
Straightforward access to block and gradient light-responsive poly(2-oxazoline)s via cationic ring opening polymerization of 2-azobenzenyl-2-oxazolineExternal link
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T. Wloka, S. Czich, F. Chalupa-Gantner, M. Sittig, M. Dirauf, C. Weber, M. Gottschaldt, K. Liefeith, A. Ovsianikov, B. Dietzek-Ivanšić, U. S. Schubert
New water-soluble photo-initiators for two-photon polymerization based on benzylidene cyclopentanonesExternal link
J. Photochem. Photobiol. A: Chem. 2023, 442, 114743.

T. X. Yang, A. Valavalkar, A. Romero-Arenas, A. Dasgupta, P. Then, A. Chettri, C. Eggeling, A. Ros, U. Pischel, B. Dietzek-Ivansic
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Chem. Eur. J. 2023, 29, e202203468.

D. Zahn, J. Landers, M. Diegel, S. Salamon, A. Stihl, F. H. Schacher, H. Wende, J. Dellith, S. Dutz
Optimization of magnetic cobalt ferrite nanoparticles for magnetic heating applications in biomedical technologyExternal link
Nanomaterials 2023, 13 (10), 1673.

N. E. Göppert, A. Vollrath, L. M. Stafast, S. Stumpf, B. Schulze, S. Hoeppener, C. Weber, U. S. Schubert
How introduction of hydrolyzable moieties in pox influences particle formation – A Library approach based on block copolymers comprising polyestersExternal link
RSC Appl. Polym. 2023, 2, 184-195.

Y. Köster, J. Kimmig, S. Zechel, U. S. Schubert
Fingerprint Applicable for Machine Learning Tested on LCST Behavior of PolymersExternal link
Cell Reports Phys. Sci. 2023, 4 (9), 101553.

J. M. Peschel, L. S. Reichel, T. Hoffmann, C. Enzensperger, U. S. Schubert, A. Traeger, M. Gottschaldt
Modification of Branched Poly(ethylene imine) with Fructose for Selective Delivery of siRNA into Human Breast Cancer CellsExternal link
Macromol. Bioscience 2023, 23, 2300135.

V. Ebrahimi, T. Stephan, J. Kim, P. Carravilla, C. Eggeling, S. Jakobs & K. Y. Han
Author Correction: Deep learning enables fast, gentle STED microscopyExternal link
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M. Ringleb, T. Schuett, S. Zechelab, U. S. Schubert
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Lukas K. Peltner, L. G., F. Boerner, N. C. Gilbert, O. Werz, P. M. Jordan,
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V. Ebrahimi, T. Stephan, J. Kim, P. Carravilla, C. Eggeling, S. Jakobs, K. Y. Han
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I. Urbančič, C. Eggeling, E. Sezgin
Do lipids tune B cell signaling?External link
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F. Behrendt, Z. Cseresnyés, R. Gerst, M. Gottschaldt, M. T. Figge, U. S. Schubert,
Evaluation of reproducible cryogel preparation based on automated image analysis using deep learningExternal link
J. Biomed. Mater. Res., Part A 2023, 111 (11), 1734-1749.

N. E. Göppert, S. Quader, J. F. R. Van Guyse, C. Weber, K. Kataoka, U. S. Schubert
Amphiphilic poly(2-oxazoline)s with glycine-containing hydrophobic blocks tailored for panobinostat- and imatinib-loaded micellesExternal link
Biomacromolecules 2023, 24 (12), 5915-5925.

N. E. Göppert, A. Vollrath, L. M. Stafast, S. Stumpf, B. Schulze, S. Hoeppener, C. Weber, U. S. Schubert
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C. Neu, B. Wissuwa, C. Thiemermann, S. M. Coldewey
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H. Bae, M. Rodewald, T. Meyer-Zedler, T. W. Bocklitz, G. Matz, B. Messerschmidt, A. T. Press, M. Bauer, O. Guntinas-Lichius, A. Stallmach, M. Schmitt, J. Popp
Feasibility studies of multimodal nonlinear endoscopy using multicore fiber bundles for remote scanning from tissue sections to bulk organsExternal link
Sci. Rep. 2023, 13 (1), 13779.

P. Dahlke, L. K. Peltner, P. M. Jordan, O. Werz
Differential impact of 5-lipoxygenase-activating protein antagonists on the biosynthesis of leukotrienes and of specialized pro-resolving mediatorsExternal link
Front. Pharmacol. 2023, 14, 1219160.

F. Dellbrügge, L. D. Jesse, A. Medyukhina, N. Liu, S. Neugebauer, M. Freißmuth, S. Höppener, M. T. Figge, H. Morrison, L. B. Riecken, A. T. Press
Contribution of radixin and ezrin to the maintenance of hepatocytes' excretory function in health and diseaseExternal link
Heliyon 2023, 9(11), e21009.

A. Fruntke, M. Behnke, E. Dietel, A. Vollrath, U. S. Schubert, T. Wilke
Nanomedizin im Chemieunterricht: Zielgerichteter Wirkstofftransport mit polymeren NanopartikelnExternal link
CHEMKON 2023, 31(6), 207-214.

G. B. Garside, M. Sandoval, S. Beronja, K. L. Rudolph
Lentiviral in situ targeting of stem cells in unperturbed intestinal epitheliumExternal link
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F. Guzmán-Lagunes, P. Wongsirichot, J. Winterburn, C. Guerrero Sanchez, C. Montiel
Polyhydroxyalkanoates production: A challenge for the plastic industryExternal link
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C. Häring, J. Jungwirth, J. Schroeder, B. Löffler, B. Engert, C. Ehrhardt
The local anaesthetic procaine prodrugs ProcCluster(®) and procaine hydrochloride impair SARS-CoV-2 replication and egress in vitroExternal link
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R. Heintzmann, L. Loetgering, F. Wechsler
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Optica 2023, 10(11), 1407-1416.

C. Höppener, J. K. Elter, F. H. Schacher, V. Deckert
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Small 2023, 19(20), 2206451.

J. Hülsmann, H. Lindemann, J. Wegener, M. Kühne, M. Godmann, A. Koschella, S. M. Coldewey, T. Heinze, T. Heinzel
Dually modified cellulose as a non-viral vector for the delivery and uptake of HDAC3 siRNAExternal link
Pharmaceutics, 2023, 15(12), 2659.

L. Klement, J. Drube
The interplay of FLT3 and CXCR4 in acute myeloid leukemia: an ongoing debateExternal link
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A. Koerfer, F. Reina, C. Eggeling
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V. Nischang, F. M. Witt, F. Börner, M. Gomez, P. M. Jordan, O. Werz
Frankincense preparation promotes formation of inflammation-resolving lipid mediators by manipulating lipoxygenases in human innate immune cellsExternal link
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A. Olğaç, İ. Çapan, P. Dahlke, P. M. Jordan, O. Werz, E. Banoglu
Substituted 1,2,4-triazoles as novel and selective inhibitors of leukotriene biosynthesis targeting 5-lipoxygenase-activating proteinExternal link
Acs Omega 2023, 8(34), 31293-31304.

I. E. Osadare, L. Xiong, I. Rubio, U. Neugebauer, A. T. Press, A. Ramoji, J. Popp
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E. Quansah, T. A. Shaik, E. Çevik, X. Wang, C. Höppener, T. Meyer-Zedler, V. Deckert, M. Schmitt, J. Popp, C. Krafft
Investigating biochemical and structural changes of glycated collagen using multimodal multiphoton imaging, Raman spectroscopy, and atomic force microscopyExternal link
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Z. Rao, E. Brunner, B. Giszas, A. Iyer-Bierhoff, J. Gerstmeier, F. Börner, P. M. Jordan, S. Pace, K. P. L. Meyer, R. K. Hofstetter, D. Merk, C. Paulenz, T. Heinzel, P. C. Grunert, A. Stallmach, C. N. Serhan, M. Werner, O. Werz
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Proc. Natl. Acad. Sci. U. S. A. 2023, 120(35), e2302070120.

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Quantitative analysis of peroxisome tracks using a Hidden Markov ModelExternal link
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A. Fruntke, N. Horst, C. Bley, B. Blümbott, M. Behnke, L. M. Stafast, A. Vollrath, U.S. Schubert, T. Wilke
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World J. Chem. Educ. 2023, 11, 97 – 103.

F. Behrendt, D. Pretzel, Z. Cseresnyés, M. Kleinsteuber, T. Wloka, L. Radosa, M. T. Figge, M. Gottschaldt, A. Brakhage, U. S. Schubert
Hydrophilic cryogels as potential 3D cell culture materials: Synthesis and characterization of 2-(methacrylamido) glucopyranose-based polymer scaffoldsExternal link
J. Polym. Sci. 2023, 61, 3039-3054.
2022
V. D. Lechuga-Islas, C. Guerrero-Sanchez, R. Guerrero-Santos, J. Vitz, U. S. Schubert
High-throughput/high-output experimentation in polymer researchExternal link
in Macromolecular Engineering (Eds.: N. Hadjichristidis, Y. Gnanou, K. Matyjaszewski, M. Muthukumar), 2022, pp. 1-26.

M. Trejo-Maldonado, A. Womiloju, S. Stumpf, S. Hoeppener, U. S. Schubert, L. E. Elizalde, C. Guerrero-Sanchez
Triazole-functionalized mesoporous materials based on poly(styrene-block-lactic acid): A morphology study of thin filmsExternal link
Polymers 2022, 14, 2231.

P. Klemm, J. I. Solomun, M. Rodewald, M. T. Kuchenbrod, V. G. Hänsch, F. Richter, J. Popp, C. Hertweck, S. Hoeppener, C. Bonduelle, S. Lecommandoux, A. Traeger, S. Schubert
Efficient gene delivery of tailored amphiphilic polypeptides by polyplex surfingExternal link
Biomacromolecules 2022, 23, 4718-4733.

T. Schuett, M. Wejner, J. Kimmig, S. Zechel, T. Wilke, U. S. Schubert
Improvement of high-throughput experimentation using synthesis robots by the implementation of tailor-made sensorsExternal link
Polymers 2022, 14, 361.

A. Balestri, B. Lonetti, S. Harrisson, B. Farias-Mancilla, J. L. Zhang, H. Amenitsch, U. S. Schubert, C. Guerrero-Sanchez, C. Montis, D. Berti
Thermo-responsive lipophilic NIPAM-based block copolymers as stabilizers for lipid-based cubic nanoparticlesExternal link
Colloid Surf. B-Biointerfaces 2022, 220, 9.

D. Beyer, J. Hoff, O. Sommerfeld, A. Zipprich, N. Gassler, A. T. Press
The liver in sepsis: molecular mechanism of liver failure and their potential for clinical translationExternal link
Mol. Med. 2022, 28, 15.

I. Capan, P. M. Jordan, A. Olgac, B. Caliskan, C. Kretzer, O. Werz, E. Banoglu
Discovery and optimization of piperazine urea derivatives as soluble epoxide hydrolase (sEH) inhibitorsExternal link
ChemMedChem 2022, 17, 9.

M. Z. Chi, R. Gargouri, T. Schrader, K. Damak, R. Maalej, M. Sierka
Atomistic descriptors for machine learning models of solubility parameters for small molecules and polymersExternal link
Polymers 2022, 14, 11.

G. Cinar, J. I. Solomun, P. Mapfumo, A. Traeger, I. Nischang
Nanoparticle sizing in the field of nanomedicine: Power of an analytical ultracentrifugeExternal link
Anal. Chim. Acta 2022, 1205, 13.

A. Czapka, C. Grune, P. Schadel, V. Bachmann, K. Scheuer, M. Dirauf, C. Weber, A. L. Skaltsounis, K. D. Jandt, U. S. Schubert, D. Fischer, O. Werz
Drug delivery of 6-bromoindirubin-3 '-glycerol-oxime ether employing poly(D,L-lactide-co-glycolide)-based nanoencapsulation techniques with sustainable solventsExternal link
J. Nanobiotechnol. 2022, 20, 21.

A. De San Luis, M. Kleinsteuber, T. Schuett, S. Schubert, U. S. Schubert
Miniemulsion polymerization at low temperature: A strategy for one-pot encapsulation of hydrophobic anti-inflammatory drugs into polyester-containing nanoparticlesExternal link
J. Colloid Interface Sci. 2022, 612, 628-638.

N. Devi, C. Cokca, R. Sharma, M. Kumar, K. Peneva, R. K. Sharma, N. Wangoo
Fabrication of cell penetrating peptide labelled biodegradable poly (methacrylamide) nanoparticles for delivery of doxorubicin in HeLa cellsExternal link
Mater. Today Commun. 2022, 33, 11.

M. Dirauf, I. Muljajew, C. Weber, U. S. Schubert
Recent advances in degradable synthetic polymers for biomedical applications-Beyond polyestersExternal link
Prog. Polym. Sci. 2022, 129, 40.

J. Drube, R. S. Haider, E. S. F. Matthees, M. Reichel, J. Zeiner, S. Fritzwanker, C. Ziegler, S. Barz, L. Klement, J. Filor, V. Weitzel, A. Kliewer, E. Miess-Tanneberg, E. Kostenis, S. Schulz, C. Hoffmann
GPCR kinase knockout cells reveal the impact of individual GRKs on arrestin binding and GPCR regulationExternal link
Nat. Commun. 2022, 13, 18.

R. Eckenstaler, A. Ripperger, M. Hauke, M. Petermann, S. A. Hemkemeyer, E. Schwedhelm, S. Ergun, M. Frye, O. Werz, A. Koeberle, H. Braun, R. A. Benndorf
A thromboxane A(2) receptor-driven COX-2-dependent feedback loop that affects endothelial homeostasis and angiogenesisExternal link
Arterioscler. Thromb. Vasc. Biol. 2022, 42, 444-461.

A. G. Ergul, T. G. Maz, C. Kretzer, A. Olgac, P. M. Jordan, B. Caliskan, O. Werz, E. Banoglu
Novel potent benzimidazole-based microsomal prostaglandin E-2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C-4 synthaseExternal link
Eur. J. Med. Chem. 2022, 231, 13.

W. Foo, A. Wiede, S. Bierwirth, R. Heintzmann, A. T. Press, W. Hauswald
Automated multicolor mesoscopic imaging for the 3-dimensional reconstruction of fluorescent biomarker distribution in large tissue specimensExternal link
Biomed. Opt. Express 2022, 13, 3723-3742.

M. Gabel, A. Knauss, D. Fischer, M. F. Neurath, B. Weigmann
Surface Design Options in Polymer- and Lipid-Based siRNA Nanoparticles Using AntibodiesExternal link
Int. J. Mol. Sci. 2022, 23, 22.

E. Gardey, F. H. Sobotta, S. Quickert, T. Bruns, J. C. Brendel, A. Stallmach
ROS-sensitive polymer micelles for selective degradation in primary human monocytes from patients with active IBDExternal link
Macromol. Biosci. 2022, 22, 6.

C. Grune, C. Kretzer, S. Zergiebel, S. Kattner, J. Thamm, S. Hoeppener, O. Werz, D. Fischer
Encapsulation of the anti-inflammatory dual FLAP/sEH inhibitor diflapolin improves the efficiency in human whole bloodExternal link
J. Pharm. Sci. 2022, 111, 1843-1850.

F. Hausig-Punke, F. Richter, M. Hoernke, J. C. Brendel, A. Traeger
Tracking the endosomal escape: A closer look at calcein and related reportersExternal link
Macromol. Biosci. 2022, 22, 26.

T. N. M. Hoang, Z. Cseresnyes, S. Hartung, M. Blickensdorf, C. Saffer, K. Rennert, A. S. Mosig, M. Von Lilienfeld-Toal, M. T. Figge
Invasive aspergillosis-on-chip: A quantitative treatment study of human Aspergillus fumigatus infectionExternal link
Biomaterials 2022, 283, 14.

B. Hoffmann, R. Gerst, Z. Cseresnyes, W. Foo, O. Sommerfeld, A. T. Press, M. Bauer, M. T. Figge
Spatial quantification of clinical biomarker pharmacokinetics through deep learning-based segmentation and signal-oriented analysis of MSOT dataExternal link
Photoacoustics 2022, 26, 12.

A. Jimenez-Victoria, R. D. Peralta-Rodriguez, E. Saldivar-Guerra, G. Y. Cortez-Mazatan, L. D. A. Soriano-Melgar, C. Guerrero-Sanchez
Emulsion polymerization using an amphiphilic oligoether ionic liquid as a surfactantExternal link
Polymers 2022, 14, 19.

C. Kretzer, P. M. Jordan, R. Bilancia, A. Rossi, T. G. Maz, E. Banoglu, U. S. Schubert, O. Werz
Shifting the biosynthesis of leukotrienes toward specialized pro-resolving mediators by the 5-lipoxygenase-activating protein (FLAP) antagonist BRP-201External link
J. Inflamm. Res. 2022, 15, 911-925.

H. Lindemann, T. Heinze
Cellulose allylcarbamate with high content of reactive double bonds for thiol-ene reactionExternal link
React. Funct. Polym. 2022, 176, 5.

N. Liu, M. Bauer, A. T. Press
The immunological function of CXCR2 in the liver during sepsisExternal link
J. Inflamm. 2022, 19, 13.

L. Miek, P. M. Jordan, K. Gunther, S. Pace, T. Beyer, D. Kowalak, V. Hoerr, B. Loffler, L. Tuchscherr, C. N. Serhan, J. Gerstmeier, O. Werz
Staphylococcus aureus controls eicosanoid and specialized pro-resolving mediator production via lipoteichoic acidExternal link
Immunology 2022, 166, 47-67.

F. L. Portwich, Y. Carstensen, A. Dasgupta, S. Kupfer, R. Wyrwa, H. Gorls, C. Eggeling, B. Dietzek, S. Grafe, M. Wachtler, R. Kretschmer
A highly fluorescent dinuclear aluminium complex with near-unity quantum yieldExternal link
Angew. Chem. Int. Ed. 2022, 61, 5.

M. Potenza, A. Giordano, M. G. Chini, A. Saviano, C. Kretzer, F. Raucci, M. Russo, G. Lauro, S. Terracciano, I. Bruno, M. Iorizzi, R. K. Hofstetter, S. Pace, F. Maione, O. Werz, G. Bifulco
Identification of 2-aminoacyl-1,3,4-thiadiazoles as prostaglandin E-2 and leukotriene biosynthesis inhibitorsExternal link
ACS Med. Chem. Lett. 2022, 14, 26-34.

Z. G. Rao, D. Caprioglio, A. Gollowitzer, C. Kretzer, D. Imperio, J. A. Collado, L. Waltl, S. Lackner, G. Appendino, E. Munoz, V. Temml, O. Werz, A. Minassi, A. Koeberle
Rotational constriction of curcuminoids impacts 5-lipoxygenase and mPGES-1 inhibition and evokes a lipid mediator class switch in macrophagesExternal link
Biochem. Pharmacol. 2022, 203, 16.

M. Reichel, V. Weitzel, L. Klement, C. Hoffmann, J. Drube
Suitability of GRK antibodies for individual detection and quantification of GRK isoforms in western blotsExternal link
Int. J. Mol. Sci. 2022, 23, 1195.

I. Richter, S. Radosa, Z. Cseresnyes, I. Ferling, H. Buttner, S. P. Niehs, R. Gerst, K. Scherlach, M. T. Figge, F. Hillmann, C. Hertweck
Toxin-producing endosymbionts shield pathogenic fungus against micropredatorsExternal link
mBio 2022, 13, 16.

A. Saviano, S. De Vita, M. G. Chini, N. Marigliano, G. Lauro, G. M. Casillo, F. Raucci, M. Iorizzi, R. K. Hofstetter, K. Fischer, A. Koeberle, O. Werz, F. Maione, G. Bifulco
In silico, in vitro and in vivo analysis of tanshinone IIA and cryptotanshinone from salvia miltiorrhiza as modulators of cyclooxygenase-2/mPGES-1/endothelial prostaglandin EP3 pathwayExternal link
Biomolecules 2022, 12, 26.

F. Siwczak, Z. Cseresnyes, M. I. A. Hassan, K. O. Aina, S. Carlstedt, A. Sigmund, M. Groger, B. G. J. Surewaard, O. Werz, M. T. Figge, L. Tuchscherr, B. Loffler, A. S. Mosig
Human macrophage polarization determines bacterial persistence of Staphylococcus aureus in a liver-on-chip-based infection modelExternal link
Biomaterials 2022, 287, 12.

J. I. Solomun, L. Martin, P. Mapfumo, E. Moek, E. Amro, F. Becker, S. Tuempel, S. Hoeppener, K. L. Rudolph, A. Traeger
pH-sensitive packaging of cationic particles by an anionic block copolymer shellExternal link
J. Nanobiotechnol. 2022, 20, 17.

G. K. Soni, N. Wangoo, C. Cokca, K. Peneva, R. K. Sharma
Ultrasensitive aptasensor for arsenic detection using quantum dots and guanylated poly(methacrylamide)External link
Anal. Chim. Acta 2022, 1209, 10.

L. M. Stafast, C. Weber, M. T. Kuchenbrod, S. Hoeppener, M. Behnke, S. Schubert, K. Mehmetaj, A. T. Press, M. Bauer, U. S. Schubert
Poly(2-oxazoline) homopolymers and diblock copolymers containing retinoate omega-end groupsExternal link
ACS Appl. Polym. Mater. 2022, 4, 3417-3425.

M. M. Suo, M. K. Rommelfanger, Y. L. Chen, E. M. Amro, B. Han, Z. Y. Chen, K. Szafranski, S. R. Chakkarappan, B. O. Boehm, A. L. MacLean, K. L. Rudolph
Age-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in miceExternal link
Blood 2022, 139, 2653-2665.

I. Terzioglu, C. Ventura-Hunter, J. Ulbrich, E. Saldivar-Guerra, U. S. Schubert, C. Guerrero-Sanchez
Automated parallel dialysis for purification of polymersExternal link
Polymers 2022, 14, 12.

S. Turanli, A. G. Ergul, P. M. Jordan, A. Olgac, B. Caliskan, O. Werz, E. Banoglu
Quinazoline-4(3H)-one-7-carboxamide derivatives as human soluble epoxide hydrolase inhibitors with developable 5-lipoxygenase activating protein inhibitionExternal link
ACS Omega 2022, 7, 36354–36365.

C. Ventura-Hunter, V. D. Lechuga-Islas, J. Ulbrich, C. Kellner, U. S. Schubert, E. Saldivar-Guerra, M. Rosales-Guzman, C. Guerrero-Sanchez
Glycerol methacrylate-based copolymers: Reactivity ratios, physicochemical characterization and cytotoxicityExternal link
Eur. Polym. J. 2022, 178, 111478.

L. Vieider, E. Zoeller, E. Romp, M. Schoenthaler, V. Hernandez-Olmos, V. Temml, T. Hasenoehrl, D. Schuster, O. Werz, U. Garscha, B. Matuszczak
Synthesis and structure-activity relationships for some novel diflapolin derivatives with benzimidazole subunitExternal link
J. Enzym. Inhib. Med. Chem. 2022, 37, 1752-1764.

M. Wejner, T. Wilke
LabPi: A digital measuring station for STEM education 4.0External link
J. Chem. Educ. 2022, 99, 819-827.

X. B. Yao, C. Hoppener, H. Schneidewind, S. Hoeppener, Z. A. Tang, A. Buchholz, A. Konig, S. Mogavero, M. Diegel, J. Dellith, A. Turchanin, W. Plass, B. Hube, V. Deckert
Targeted suppression of peptide degradation in Ag-based surface-enhanced Raman spectra by depletion of hot carriersExternal link
Small 2022, 18, 2205080.

K. H. Zhang, P. M. Jordan, S. Pace, R. K. Hofstetter, M. Werner, X. C. Chen, O. Werz
Modulation of inflammation-related lipid mediator pathways by celastrol during human macrophage polarizationExternal link
J. Inflamm. Res. 2022, 15, 3285-3304.

Z. Wallace, J. Kopycinski, H. Yang, M. L. McCully, C. Eggeling, J. Chojnacki, L. Dorrell
Immune mobilising T cell receptors redirect polyclonal CD8+ T cells in chronic HIV infection to form immunological synapsesExternal link
Sci. Rep. 2022, (12), 13.

S. Insausti, M. Garcia-Porras, J. Torralba, I. Morillo, A. Ramos-Caballero, I. de la Arada, B. Apellaniz, J. M. M. Caaveiro, P. Carravilla, C. Eggeling, E. Rujas, J. L. Nieva
Functional delineation of a protein–membrane interaction hotspot site on the HIV-1 neutralizing antibody 10E8External link
Int. J. Mol. Sci. 2022, 23 (18), 17.

S. Galiani, K. Reglinski, P. Carravilla, A. Barbotin, I. Urbancic, J. Ott, J. Sehr, E. Sezgin, F. Schneider, D. Waithe, P. Hublitz, W. Schliebs, R. Erdmann, C. Eggeling
Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5External link
Biophys. Rep. 2022, (2), 15.

H. Lindemann, T. Heinze,
Cellulose allylcarbamate with high content of reactive double bonds for thiol-ene reactionExternal link
React. Funct. Polym. 2022, 176, 105306.

N. E. Goppert, M. Dirauf, P. Liebing, C. Weber, U. S. Schubert
Organocatalyzed ring-opening polymerization of (S)-3-benzylmorpholine-2,5-dioneExternal link
Macromol. Rapid Commun. 2022, 44, 6.
2021
C. Kretzer, B. Shkodra, P. Klemm, P. M. Jordan, D. Schröder, G. Cinar, A. Vollrath, S. Schubert, I. Nischang, S. Hoeppener, S. Stumpf, E. Banoglu, F. Gladigau, R. Bilancia, A. Rossi, C. Eggeling, U. Neugebauer, U. S. Schubert, O. Werz
Ethoxy acetalated dextran-based nanocarriers accomplish efficient inhibition of leukotriene formation by a novel FLAP antagonist in human leukocytes and bloodExternal link
Cell. Mol. Life Sci. 2021, 79, 40.

A. M. Ali, M. Egiza, K. Murasawa, H. Sugita, T. Deckert-Gaudig, V. Deckert, T. Yoshitake
Effects of substrate temperature and intermediate layer on adhesion, structural and mechanical properties of coaxial arc plasma deposition grown nanodiamond composite films on Si substratesExternal link
Surf. Coat. Technol. 2021, 417, 127185.

T. T. V. Anh, A. Mostafa, Z. G. Rao, S. Pace, S. Schwaiger, C. Kretzer, V. Temml, C. Giesel, P. M. Jordan, R. Bilancia, C. Weinigel, S. Rummler, B. Waltenberger, T. Hung, A. Rossi, H. Stuppner, O. Werz, A. Koeberle
From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolutionExternal link
Acta Pharmaceutica Sinica B 2021, 11, 1629-1647.

M. Brunzel, M. Dirauf, M. Sahn, J. A. Czaplewska, N. Fritz, C. Weber, I. Nischang, U. S. Schubert
On the identification and quantification of proton-initiated species in the synthesis of poly(2-alkyl-2-oxazoline)s by high resolution liquid chromatographyExternal link
J. Chromatogr. A 2021, 1653, 462364.

H. Büttner, S. P. Niehs, K. Vandelannoote, Z. Cseresnyés, B. Dose, I. Richter, R. Gerst, M. T. Figge, T. P. Stinear, S. J. Pidot, C. Hertweck
Bacterial endosymbionts protect beneficial soil fungus from nematode attackExternal link
PNAS 2021, 118, e2110669118.

C. Chen, F. Richter, J. L. Zhang, C. Guerrero-Sanchez, A. Traeger, U. S. Schubert, A. C. Feng, S. H. Thang
Synthesis of functional miktoarm star polymers in an automated parallel synthesizerExternal link
Eur. Polym. J. 2021, 160, 110777.

Y. L. Chen, K. L. Rudolph
Granulocyte colony-stimulating factor acts on lymphoid-biased, short-term hematopoietic stem cellsExternal link
Haematologica 2021, 106, 1516-1518.

C. Cokca, F. J. Hack, D. Costabel, K. Herwig, J. Hulsmann, P. Then, R. Heintzmann, D. Fischer, K. Peneva
PEGylation of guanidinium and indole bearing poly(methacrylamide)s - Biocompatible terpolymers for pDNA deliveryExternal link
Macromol. Biosci. 2021, 21, 2100146.

E. Y. Darussalam, O. Peterfi, T. Deckert-Gaudig, L. Roussille, V. Deckert
pH-dependent disintegration of insulin amyloid fibrils monitored with atomic force microscopy and surface-enhanced Raman spectroscopyExternal link
Spectrochim. Acta A Mol. Biomol. Spect. 2021, 256, 119672.

M. A. De Jesus-Tellez, S. De la Rosa-Garcia, I. Medrano-Galindo, I. Rosales-Penafiel, S. Gomez-Cornelio, C. Guerrero-Sanchez, U. S. Schubert, P. Quintana-Owen
Antifungal properties of poly 2-(dimethylamino)ethyl methacrylate (PDMAEMA) and quaternized derivativesExternal link
React. Funct. Polym. 2021, 163, 104887.

S. Deb, D. A. Felix, P. Koch, M. K. Deb, K. Szafranski, K. Buder, M. Sannai, M. Groth, J. Kirkpatrick, S. Pietsch, A. Gollowitzer, A. Gross, P. Riemenschneider, A. Koeberle, C. Gonzalez-Estevez, K. L. Rudolph
Tnfaip2/exoc3-driven lipid metabolism is essential for stem cell differentiation and organ homeostasisExternal link
EMBO Rep. 2021, 22, e49328.

S. Deinhardt-Emmer, S. Bottcher, C. Haring, L. Giebeler, A. Henke, R. Zell, J. Jungwirth, P. M. Jordan, O. Werz, F. Hornung, C. Brandt, M. Marquet, A. S. Mosig, M. W. Pletz, M. Schacke, J. Rodel, R. Heller, S. Nietzsche, B. Loffler, C. Ehrhardt
SARS-CoV-2 causes severe epithelial inflammation and barrier dysfunctionExternal link
J. Virol. 2021, 95, e00110-21.

M. Dirauf, N. Fritz, M. Gottschaldt, C. Weber, U. S. Schubert
Poly(2-ethyl-2-oxazoline) featuring a central amino moietyExternal link
Macromol. Rapid Commun. 2021, 42, 2100132.

D. Fischer, N. Dusek, K. Hotzel, T. Heinze
The role of formamidine groups in dextran based nonviral vectors for gene delivery on their physicochemical and biological characteristicsExternal link
Macromol. Biosci. 2021, 21, 2000220.

L. Friedrich, G. Cingolani, Y. H. Ko, M. Iaselli, M. Miciaccia, M. G. Perrone, K. Neukirch, V. Bobinger, D. Merk, R. K. Hofstetter, O. Werz, A. Koeberle, A. Scilimati, G. Schneider
Learning from nature: From a marine natural product to synthetic cyclooxygenase-1 inhibitors by automated de novo designExternal link
Adv. Sci. 2021, 8, 2100832.

A. N. Garcia-Sanchez, R. Yanez-Macias, J. L. Hernandez-Flores, A. Alvarez-Morales, J. H. Valenzuela-Soto, C. Guerrero-Sanchez, R. Guerrero-Santos
Exogenous application of polycationic nanobactericide on tomato plants reduces the candidatus liberibacter solanacearum infectionExternal link
Plants 2021, 10, 2096.

N. C. Gilbert, M. E. Newcomer, O. Werz
Untangling the web of 5-lipoxygenase-derived products from a molecular and structural perspective: The battle between pro- and anti-inflammatory lipid mediatorsExternal link
Biochem. Pharmacol. 2021, 193, 114759.

N. E. Göppert, M. Dirauf, C. Weber, U. S. Schubert
Block copolymers comprising degradable poly(2-ethyl-2-oxazoline) analogues via copper-free click chemistryExternal link
Polym. Chem. 2021, 12, 5426–5437.

C. Grune, C. Zens, A. Czapka, K. Scheuer, J. Thamm, S. Hoeppener, K. D. Jandt, O. Werz, U. Neugebauer, D. Fischer
Sustainable preparation of anti-inflammatory atorvastatin PLGA nanoparticlesExternal link
Int. J. Pharm. 2021, 599, 120404.

F. V. Gruschwitz, T. Klein, M. T. Kuchenbrod, N. Moriyama, S. Fujii, I. Nischang, S. Hoeppener, K. Sakurai, U. S. Schubert, J. C. Brendel
Kinetically controlling the length of self-assembled polymer nanofibers formed by intermolecular hydrogen bondsExternal link
ACS Macro Lett. 2021, 10, 837-843.

T. Gürses, A. Olğaç, U. Garscha, T. Gür Maz, N. B. Bal, O. Uludağ, B. Çalışkan, U. S. Schubert, O. Werz, E. Banoglu
Simple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacyExternal link
Bioorg. Chem. 2021, 112, 104861.

O. Gutierrez-Gutierrez, D. A. Felix, A. Salvetti, E. M. Amro, A. Thems, S. Pietsch, A. Koeberle, K. L. Rudolph, C. Gonzalez-Estevez
Regeneration in starved planarians depends on TRiC/CCT subunits modulating the unfolded protein responseExternal link
EMBO Rep. 2021, 22, e52905.

S. Hanio, J. Schlauersbach, B. Lenz, F. Spiegel, R. A. Böckmann, R. Schweins, I. Nischang, U. S. Schubert, S. Endres, A.-C. Pöppler, F. P. Brandl, T. M. Smit, K. Kolter, L. Meinel
Drug-induced dynamics of bile colloidsExternal link
Langmuir 2021, 37, 2543-2551.

M. I. A. Hassan, M. Keller, M. Hillger, U. Binder, S. Reuter, K. Herold, A. Telagathoti, H.-M. Dahse, S. Wicht, N. Trinks, S. Nietzsche, T. Deckert-Gaudig, V. Deckert, R. Mrowka, U. Terpitz, H. Peter Saluz, K. Voigt
The impact of episporic modification of Lichtheimia corymbifera on virulence and interaction with phagocytesExternal link
Comput. Struct. Biotechnol. J. 2021, 19, 880-896.

F. Hausig, F. H. Sobotta, F. Richter, D. O. Harz, A. Traeger, J. C. Brendel
Correlation between protonation of tailor-made polypiperazines and endosomal escape for cytosolic protein deliveryExternal link
ACS Appl. Mater. Interfaces 2021, 13, 35233-35247.

R. Heintzmann
Answers to fundamental questions in superresolution microscopyExternal link
Philos. Trans. A Math. Phys. Eng. Sci. 2021, 379.

P. M. Jordan, N. Andreas, M. Groth, P. Wegner, F. Weber, U. Jager, C. Kuchler, O. Werz, E. Serfling, T. Kamradt, A. Dudeck, S. Drube
ATP/IL-33-triggered hyperactivation of mast cells results in an amplified production of pro-inflammatory cytokines and eicosanoidsExternal link
Immunology 2021, 164, 541-554.

P. M. Jordan, O. Werz
Specialized pro-resolving mediators: Biosynthesis and biological role in bacterial infectionsExternal link
FEBS J. 2021, DOI: 10.1111/febs.16266

T. Kammann, J. Hoff, I. Yildirim, B. Shkodra, T. Müller, C. Weber, M. H. Gräler, U. A. Maus, J. C. Paton, M. Singer, A. Traeger, U. S. Schubert, M. Bauer, A. T. Press
Intracellularly released cholesterol from polymer-based delivery systems alters cellular responses to pneumolysin and promotes cell survivalExternal link
Metabolites 2021, 11, 821.

J. Kimmig, T. Schuett, A. Vollrath, S. Zechel, U. S. Schubert
Prediction of nanoparticle sizes for arbitrary methacrylates using artificial neuronal networksExternal link
Adv. Sci. 2021, 8, 2102429.

J. Kimmig, S. Zechel, U. S. Schubert
Digital transformation in materials science: A paradigm change in material's developmentExternal link
Adv. Mater. 2021, 33, 2004940.

T. Klein, F. V. Gruschwitz, M. T. Kuchenbrod, I. Nischang, S. Hoeppener, J. C. Brendel
Adjusting the length of supramolecular polymer bottlebrushes by top-down approachesExternal link
Beilst. J. Org. Chem. 2021, 17, 2621-2628.

T. Klein, H. F. Ulrich, F. V. Gruschwitz, M. T. Kuchenbrod, R. Takahashi, S. Hoeppener, I. Nischang, K. Sakurai, J. C. Brendel
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Macromol. Rapid Commun. 2021, 42, 2000585.

P. Klemm, M. Behnke, J. I. Solomun, C. Bonduelle, S. Lecommandoux, A. Traeger, S. Schubert
Self-assembled PEGylated amphiphilic polypeptides for gene transfectionExternal link
J. Mater. Chem. B 2021, 9, 8149-8356.

S. Kluge, M. Schubert, L. Bormel, S. Lorkowski
The vitamin E long-chain metabolite alpha-13 '-COOH affects macrophage foam cell formation via modulation of the lipoprotein lipase systemExternal link
Biochim. Biophys. Acta - Mol. Cell Biol. Lipids 2021, 1866, 158875.

M. Kohler, P. Rinke, K. Fiederling, H. Gorls, N. Ueberschaar, F. H. Schacher, R. Kretschmer
Catalytic activity of various beta-diketiminate zinc complexes toward the ring-opening polymerization of caprolactone and derivativesExternal link
Macromol. Chem. Phys. 2021, 222, 2100187.

B. Kokot, H. Kokot, P. Umek, K. P. van Midden, S. Pajk, M. Garvas, C. Eggeling, T. Koklic, I. Urbancic, J. Strancar
How to control fluorescent labeling of metal oxide nanoparticles for artefact-free live cell microscopyExternal link
Nanotoxicology 2021, 15, 1102-1123.

M. Kuhne, C. Kretzer, H. Lindemann, M. Godmann, T. Heinze, O. Werz, T. Heinzel
Biocompatible valproic acid-coupled nanoparticles attenuate lipopolysaccharide-induced inflammationExternal link
Int. J. Pharm. 2021, 601, 120567.

M. Kuhne, H. Lindemann, C. Grune, D. Schroder, Z. Cseresnyes, M. Godmann, A. Koschella, M. T. Figge, C. Eggeling, D. Fischer, T. Heinze, T. Heinzel
Biocompatible sulfated valproic acid-coupled polysaccharide-based nanocarriers with HDAC inhibitory activityExternal link
J. Control. Release 2021, 329, 717-730.

V. D. Lechuga-Islas, M. Trejo-Maldonado, S. Stumpf, R. Guerrero-Santos, L. Elizalde-Herrera, U. S. Schubert, C. Guerrero-Sanchez
Separation of volatile compounds from polymers by physisorptionExternal link
Eur. Polym. J. 2021, 159, 110748.

K. Leer, G. Cinar, J. I. Solomun, L. Martin, I. Nischang, A. Traeger
Core-crosslinked, temperature- and pH-responsive micelles: design, physicochemical characterization, and gene delivery applicationExternal link
Nanoscale 2021, 13, 19412-19429.

B. Loffler, L. Tuchscherr
Staphylococcus aureus toxins: Promoter or handicap during infection?External link
Toxins 2021, 13, 287.

I. Muljajew, M. Chi, A. Vollrath, C. Weber, B. Beringer-Siemers, S. Stumpf, S. Hoeppener, M. Sierka, U. S. Schubert
A combined experimental and in silico approach to determine the compatibility of poly(ester amide)s and indomethacin in polymer nanoparticlesExternal link
Eur. Polym. J. 2021, 156, 110606.

I. Muljajew, S. Huschke, A. Ramoji, Z. Cseresnyés, S. Hoeppener, I. Nischang, W. Foo, J. Popp, M. T. Figge, C. Weber, M. Bauer, U. S. Schubert, A. T. Press
Stealth effect of short polyoxazolines in graft copolymers: Minor changes of backbone end group determine liver cell-type specificityExternal link
ACS Nano 2021, 15, 12298–12313

K. Neukirch, K. Alsabil, C. P. Dinh, R. Bilancia, M. Raasch, A. Ville, I. Cerqua, G. Viault, D. Breard, S. Pace, V. Temml, E. Brunner, P. M. Jordan, M. C. Marques, K. Loeser, A. Gollowitzer, S. Permann, J. Gerstmeier, S. Lorkowski, H. Stuppner, U. Garscha, T. Rodrigues, G. J. L. Bernardes, D. Schuster, D. Seraphin, P. Richomme, A. Rossi, A. S. Mosig, F. Roviezzo, O. Werz, J. J. Helesbeux, A. Koeberle
Exploration of long-chain vitamin E metabolites for the discovery of a highly potent, orally effective, and metabolically stable 5-LOX Inhibitor that limits inflammationExternal link
J. Med. Chem. 2021, 64, 11496-11526.

M. F. Osuchowski, M. S. Winkler, T. Skirecki, S. Cajander, M. Shankar-Hari, G. Lachmann, G. Monneret, F. Venet, M. Bauer, F. M. Brunkhorst, S. Weis, A. Garcia-Salido, M. Kox, J.-M. Cavaillon, F. Uhle, M. A. Weigand, S. B. Flohé, W. J. Wiersinga, R. Almansa, A. de la Fuente, I. Martin-Loeches, C. Meisel, T. Spinetti, J. C. Schefold, C. Cilloniz, A. Torres, E. J. Giamarellos-Bourboulis, R. Ferrer, M. Girardis, A. Cossarizza, M. G. Netea, T. van der Poll, J. F. Bermejo-Martín, I. Rubio
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entityExternal link
The Lancet Respiratory Medicine 2021, 9, 622-642.

S. Pace, K. Zhang, P. M. Jordan, R. Bilancia, W. Wang, F. Börner, R. K. Hofstetter, M. Potenza, C. Kretzer, J. Gerstmeier, D. Fischer, S. Lorkowski, N. C. Gilbert, M. E. Newcomer, A. Rossi, X. Chen, O. Werz
Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediatorsExternal link
Pharmacol. Res. 2021, 167, 105556.

H. Penkert, A. Bertrand, V. Tiwari, S. Breimann, S. A. Muller, P. M. Jordan, M. J. Gerl, C. Klose, L. Cantuti-Castelvetri, M. Bosch-Queralt, I. Levental, S. F. Lichtenthaler, O. Werz, M. Simons
Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recoveryExternal link
Cell Reports 2021, 37, 109898.

M. Potenza, M. Sciarretta, M. G. Chini, A. Saviano, F. Maione, M. V. D'Auria, S. De Marino, A. Giordano, R. K. Hofstetter, C. Festa, O. Werz, G. Bifulco
Structure-based screening for the discovery of 1,2,4-oxadiazoles as promising hits for the development of new anti-inflammatory agents interfering with eicosanoid biosynthesis pathwaysExternal link
Eur. J. Med. Chem. 2021, 224, 113693.

A. T. Press, P. Babic, B. Hoffmann, T. Müller, W. Foo, W. Hauswald, J. Benecke, M. Beretta, Z. Cseresnyés, S. Hoeppener, I. Nischang, S. M. Coldewey, M. H. Gräler, R. Bauer, F. Gonnert, N. Gaßler, R. Wetzker, M. T. Figge, U. S. Schubert, M. Bauer
Targeted delivery of a phosphoinositide 3-kinase γ inhibitor to restore organ function in sepsisExternal link
EMBO Mol. Med. 2021, 13, e14436.

L. Pusch, R. Brox, K. Scheuer, T. Yokosawa, M. Wu, B. A. Zubiri, E. Spiecker, K. D. Jandt, D. Fischer, H. Hackstein
Distinct endocytosis and immune activation of poly(lactic-co-glycolic) acid nanoparticles prepared by single- and double-emulsion evaporationExternal link
Nanomedicine 2021, 16, 2075-2094.

F. Richter, K. Leer, L. Martin, P. Mapfumo, J. I. Solomun, M. T. Kuchenbrod, S. Hoeppener, J. C. Brendel, A. Traeger
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J. Nanobiotechnol. 2021, 19, 292.

F. Richter, P. Mapfumo, L. Martin, J. I. Solomun, F. Hausig, J. J. Frietsch, T. Ernst, S. Hoeppener, J. C. Brendel, A. Traeger
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T. Ritschel, K. Lehmann, M. Brunzel, J. Vitz, I. Nischang, U. S. Schubert, K. U. Totsche
Well-defined poly(ethylene glycol) polymers as non-conventional reactive tracers of colloidal transport in porous mediaExternal link
J. Colloid Interface Sci. 2021, 584, 592-601.

M. Rodewald, H. Bae, S. Huschke, T. Meyer-Zedler, M. Schmitt, A. T. Press, S. Schubert, M. Bauer, J. Popp
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J. Biophotonics 2021, 14, e202100040.

E. Rujas, D. P. Leaman, S. Insausti, P. Carravilla, M. Garcia-Porras, E. Largo, I. Morillo, R. Sanchez-Eugenia, L. Zhang, H. Cui, I. Iloro, F. Elortza, J. P. Julien, C. Eggeling, M. B. Zwick, J. M. M. Caaveiro, J. L. Nieva
Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profileExternal link
Iscience 2021, 24, 102987.

P. Schädel, F. Troisi, A. Czapka, N. Gebert, S. Pace, A. Ori, O. Werz
Aging drives organ-specific alterations of the inflammatory microenvironment guided by immunomodulatory mediators in miceExternal link
The FASEB Journal 2021, 35, e21558.

F. Schneider, T. Sych, C. Eggeling, E. Sezgin
Influence of nanobody binding on fluorescence emission, mobility, and organization of GFP-tagged proteinsExternal link
Iscience 2021, 24, 101891.

M. Sittig, J. C. Tom, J. K. Elter, F. H. Schacher, B. Dietzek
Quinoline photobasicity: Investigation within water-soluble light-responsive copolymersExternal link
Chem. Eur. J. 2021, 27, 1072-1079.

F. H. Sobotta, M. T. Kuchenbrod, C. Grune, D. Fischer, S. Hoeppener, J. C. Brendel
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Polym. Chem. 2021, 12, 1668-1680.

F. H. Sobotta, M. T. Kuchenbrod, F. V. Gruschwitz, G. Festag, P. Bellstedt, S. Hoeppener, J. C. Brendel
Tuneable time delay in the burst release from oxidation-sensitive polymersomes made by PISAExternal link
Angew. Chem. Int. Ed. 2021, 60, 24716-24723.

O. Sommerfeld, A. Medyukhina, S. Neugebauer, M. Ghait, S. Ulferts, A. Lupp, R. König, R. Wetzker, S. Schulz, M. T. Figge, M. Bauer, A. T. Press
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Mol. Ther. 2021, 29, 338-346.

F. A. Stanford, N. Matthies, Z. Cseresnyés, M. T. Figge, M. I. A. Hassan, K. Voigt
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Journal of Fungi 2021, 7, 272.

B. H. Stumpf, P. Nowakowski, C. Eggeling, A. Maciolek, A. S. Smith
Protein induced lipid demixing in homogeneous membranesExternal link
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A. Tannert, J. G. Lopez, N. Petkov, A. Ivanova, K. Peneva, U. Neugebauer
Lysosome-targeting pH indicator based on peri-fused naphthalene monoimide with superior stability for long term live cell imagingExternal link
J. Mater. Chem. B 2021, 9, 112-124.

I. Urbancic, L. Schiffelers, E. Jenkins, W. J. Gong, A. M. Santos, F. Schneider, C. O'Brien-Ball, M. T. Vuong, N. Ashman, E. Sezgin, C. Eggeling
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FEBS Lett. 2021, 595, 2127-2146.

A. Vollrath, C. Kretzer, B. Beringer-Siemers, B. Shkodra, J. A. Czaplewska, D. Bandelli, S. Stumpf, S. Hoeppener, C. Weber, O. Werz, U. S. Schubert
Effect of crystallinity on the properties of polycaprolactone nanoparticles containing the dual FLAP/mPEGS-1 inhibitor BRP-187External link
Polymers 2021, 13, 2557.

L. Wang, U. S. Schubert, S. Hoeppener
Surface chemical reactions on self-assembled silane based monolayersExternal link
Chem. Soc. Rev. 2021, 50, 6507-6540.

L. Wang, A. A. Womiloju, C. Höppener, U. S. Schubert, S. Hoeppener
On the stability of microwave-fabricated SERS substrates – chemical and morphological considerationsExternal link
Beilst. J. Nanotechnol. 2021, 12, 541-551.

S. Willems, L. Gellrich, A. Chaikuad, S. Kluge, O. Werz, J. Heering, S. Knapp, S. Lorkowski, M. Schubert-Zsilavecz, D. Merk
Endogenous vitamin E metabolites mediate allosteric PPARγ activation with unprecedented co-regulatory interactionsExternal link
Cell Chem. Biol. 2021, 28, 1489-1500.

K. Zhang, S. Pace, P. M. Jordan, L. K. Peltner, A. Weber, D. Fischer, R. K. Hofstetter, X. Chen, O. Werz
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Biomolecules 2021, 11, 746.

J. Alex, J. Ulbrich, M. Rosales-Guzmán, C. Weber, U. S. Schubert, C. Guerrero-Sanchez
Kinetic investigations on homo- and co-polymerizations of pentafluorophenyl (meth)acrylatesExternal link
Eur. Polym. J. 2021, 143, 110175.

F. Becker, K. L. Rudolph
Targeting enzyme agingExternal link
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C. Grune, J. Thamm, O. Werz, D. Fischer
Cyrene™ as an alternative sustainable solvent for the preparation of poly(lactic-co-glycolic acid) nanoparticlesExternal link
J. Pharm. Sci. 2021, 110, 959-964.

P. Klemm, S. Huschke, M. Rodewald, N. Ehteshamzad, M. Behnke, X. Wang, G. Cinar, I. Nischang, S. Hoeppener, C. Weber, A. Press, C. Höppener, T. Meyer, V. K. Deckert, M. Schmitt, J. Popp, M. Bauer, S. Schubert
Characterization of a library of vitamin A-functionalized polymethacrylate-based nanoparticles for siRNA deliveryExternal link
Polym. Chem. 2021, DOI: 10.1039/D1030PY01626H.

K. L. Rudolph
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Mech. Ageing Dev. 2021, 193, 111394.

J. I. Solomun, G. Cinar, P. Mapfumo, F. Richter, E. Moek, F. Hausig, L. Martin, S. Hoeppener, I. Nischang, A. Traeger
Solely aqueous formulation of hydrophobic cationic polymers for efficient gene deliveryExternal link
Int. J. Pharm. 2021, 593, 120080.

C. St Thomas, L. E. Elizalde, E. J. Regalado, M. A. De Jesús-Téllez, G. Festag, U. S. Schubert, C. Guerrero-Sánchez
Understanding the influence of chemical structure and length of hydrophobic blocks on the rheological properties of associative copolymersExternal link
Eur. Polym. J. 2021, 143, 110190.

H. Wang, R. Heintzmann, B. Diederich
The power in your pocket – uncover smartphones for use as cutting-edge microscopic instruments in science and researchExternal link
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C. Guerrero-Sanchez, R. Yañez-Macias, M. Rosales-Guzmán, M. A. De Jesus-Tellez, C. Piñon-Balderrama, J. J. Haven, G. Moad, T. Junkers, U. S. Schubert
High-throughput/high-output experimentation in RAFT POLYMER synthesisExternal link
In RAFT Polymerization, 2021; pp 1051-1076.

P. Carravilla, A. Dasgupta, G. Zhurgenbayeva, D. I. Danylchuk, A. S. Klymchenko, E. Sezgin, C. Eggeling
Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyesExternal link
Biophys. Rep. 2021, 1 (2), 100023
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Optimized encapsulation of the FLAP/PGES-1 Inhibitor BRP-187 in PVA-stabilized PLGA nanoparticles using microfluidicsExternal link
Polymers 2020, 12, 2751.

S. Deb, D. A. Felix, P. Koch, M. K. Deb, K. Szafranski, K. Buder, M. Sannai, M. Groth, J. Kirkpatrick, S. Pietsch, A. Gollowitzer, A. Groß, P. Riemenschneider, A. Koeberle, C. Gonzalez-Estevez, K. L. Rudolph
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B. Diederich, R. Lachmann, S. Carlstedt, B. Marsikova, H. Wang, X. Uwurukundo, A. Mosig, R. Heintzmann
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B. Farias-Mancilla, J. Zhang, I. Kulai, M. Destarac, U. S. Schubert, C. Guerrero Sanchez, S. Harrisson, O. Colombani
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Polym. Chem. 2020, DOI: 10.1039/d1030py01059f.

N. E. Goeppert, M. Kleinsteuber, C. Weber, U. S. Schubert
Degradable poly(2-oxazoline) analogues from partially oxidized poly(ethylene imine)External link
Macromolecules 2020, 53, 10837-10846.

F. J. Hack, C. Cokca, S. Städter, J. Hülsmann, K. Peneva, D. Fischer
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C. Helbing, K. D. Jandt
Novel protein and peptide nanofibrous structures via supramolecular co-assemblyExternal link
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T. Klein, H. F. Ulrich, F. V. Gruschwitz, M. T. Kuchenbrod, R. Takahashi, S. Fujii, S. Hoeppener, I. Nischang, K. Sakurai, J. C. Brendel
Impact of amino acids on the aqueous self-assembly of benzenetrispeptides into supramolecular polymer bottlebrushesExternal link
Polym. Chem. 2020, 11, 6763-6771.

T. Klein, H. F. Ulrich, F. V. Gruschwitz, M. T. Kuchenbrod, R. Takahashi, S. Hoeppener, I. Nischang, K. Sakurai, J. C. Brendel
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Macromol. Rapid Commun. 2020, DOI: 10.1002/marc.202000585.

M. T. Kuchenbrod, R. Heintzmann, U. S. Schubert, S. Hoeppener
Revisiting staining of biological samples for electron microscopy: Perspectives for recent researchExternal link
Mater. Horiz. 2020, DOI: 10.1039/D1030MH01579B.

J. J. Lühr, N. Alex, L. Amon, M. Kräter, M. Kubánková, E. Sezgin, C. H. K. Lehmann, L. Heger, G. F. Heidkamp, A.-S. Smith, V. Zaburdaev, R. A. Böckmann, I. Levental, M. L. Dustin, C. Eggeling, J. Guck, D. Dudziak
Maturation of monocyte-derived DCs leads to increased cellular stiffness, higher membrane fluidity, and changed lipid compositionExternal link
Front. Immunol. 2020, 11, 590121.

B. Shkodra, A. T. Press, A. Vollrath, I. Nischang, S. Schubert, S. Hoeppener, D. Haas, C. Enzensperger, M. Lehmann, P. Babic, K. J. Benecke, A. Traeger, M. Bauer, U. S. Schubert
Formulation of liver-specific PLGA-DY-635 nanoparticles loaded with the protein kinase C inhibitor bisindolylmaleimide IExternal link
Pharmaceutics 2020, 12, 1110.

F. H. Sobotta, M. Kuchenbrod, S. Hoeppener, J. C. Brendel
One polymer composition, various morphologies: the decisive influence of conditions on the polymerization-induced self-assembly (PISA) of N-acryloyl thiomorpholineExternal link
Nanoscale 2020, 12, 20171-20176.

A. Tannert, J. Garcia Lopez, N. Petkov, A. Ivanova, K. Peneva, U. Neugebauer
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M. A. Ali, M. Egiza, K. Murasawa, H. Sugita, T. Deckert-gaudig, V. Deckert, T. Yoshitake
Influence of adhesion intermediate layers on the stability of nanodiamond composite films deposited on Si substrates by coaxial arc plasmaExternal link
Appl. Phys. Exp. 2020, DOI: 10.35848/31882-30786/ab35891d35841.

A. J. Beer, D. Hertz, E. Seemann, M. Beretta, M. Westermann, R. Bauer, M. Bauer, M. M. Kessels, B. Qualmann
Reduced Mrp2 surface availability as PI3Kγ-mediated hepatocytic dysfunction reflecting a hallmark of cholestasis in sepsisExternal link
Sci. Rep. 2020, 10, 13110.

S. Czich, T. Wloka, H. Rothe, J. Rost, F. Penzold, M. Kleinsteuber, M. Gottschaldt, U. S. Schubert, K. Liefeith
Two-photon polymerized poly(2-ethyl-2-oxazoline) hydrogel 3D microstructures with tunable mechanical properties for tissue engineeringExternal link
Molecules 2020, 25, 5066.

A. Dorosz, M. Grosicki, J. Dybas, E. Matuszyk, M. Rodewald, T. Meyer, J. Popp, K. Malek, M. Baranska
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Cells 2020, 9, 2041.

D. Fischer, N. Dusek, K. Hotzel, T. Heinze
The role of formamidine groups in dextran based nonviral vectors for gene delivery on their physicochemical and biological characteristicsExternal link
Macromol. Biosci. 2020, 2000220.

A. T. Frawley, V. Wycisk, Y. Xiong, S. Galiani, E. Sezgin, I. Urbančič, A. Vargas Jentzsch, K. G. Leslie, C. Eggeling, H. L. Anderson
Super-resolution RESOLFT microscopy of lipid bilayers using a fluorophore-switch dyadExternal link
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N. Gebert, C.-W. Cheng, J. M. Kirkpatrick, D. Di Fraia, J. Yun, P. Schädel, S. Pace, G. B. Garside, O. Werz, K. L. Rudolph, H. Jasper, Ö. H. Yilmaz, A. Ori
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N. C. Gilbert, J. Gerstmeier, E. E. Schexnaydre, F. Börner, U. Garscha, D. B. Neau, O. Werz, M. E. Newcomer
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F. V. Gruschwitz, M.-C. Fu, T. Klein, R. Takahashi, T. Higashihara, S. Hoeppener, I. Nischang, K. Sakurai, J. C. Brendel
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F. V. Gruschwitz, T. Klein, S. Catrouillet, J. C. Brendel
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D. Gutowska-Owsiak, E. I. Podobas, C. Eggeling, G. S. Ogg, J. Bernardino de la Serna
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P. Hummel, A. M. Lechner, K. Herrmann, P. Biehl, C. Rössel, L. Wiedenhöft, F. H. Schacher, M. Retsch
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J. B. Max, K. Kowalczuk, M. Köhler, C. Neumann, F. Pielenz, L. V. Sigolaeva, D. V. Pergushov, A. Turchanin, F. Langenhorst, F. H. Schacher
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K. Reglinski, L. Steinfort-Effelsberg, E. Sezgin, C. Klose, H. W. Platta, W. Girzalsky, C. Eggeling, R. Erdmann
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E. Rujas, S. Insausti, D. P. Leaman, P. Carravilla, S. González-Resines, V. Monceaux, R. Sánchez-Eugenia, M. García-Porras, I. Iloro, L. Zhang, F. Elortza, J.-P. Julien, A. Saéz-Cirión, M. B. Zwick, C. Eggeling, A. Ojida, C. Domene, J. M. M. Caaveiro, J. L. Nieva
Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane EnvironmentsExternal link
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E. Schicke, Z. Cseresnyés, K. Rennert, V. Vau, K. F. Haupt, F. Hornung, S. Nietzsche, F. Swiczak, M. Schmidtke, B. Glück, M. Koch, M. Schacke, R. Heller, A. S. Mosig, M. T. Figge, C. Ehrhardt, B. Löffler, S. Deinhardt-Emmer
Staphylococcus aureus lung infection results in down-regulation of surfactant protein-A mainly caused by pro-inflammatory macrophagesExternal link
Microorganisms 2020, 8, 577.

C. N. Serhan, S. K. Gupta, M. Perretti, C. Godson, E. Brennan, Y. Li, O. Soehnlein, T. Shimizu, O. Werz, V. Chiurchiù, A. Azzi, M. Dubourdeau, S. S. Gupta, P. Schopohl, M. Hoch, D. Gjorgevikj, F. M. Khan, D. Brauer, A. Tripathi, K. Cesnulevicius, D. Lescheid, M. Schultz, E. Särndahl, D. Repsilber, R. Kruse, A. Sala, J. Z. Haeggström, B. D. Levy, J. G. Filep, O. Wolkenhauer
The atlas of inflammation resolution (AIR)External link
Mol. Asp. Med. 2020, 74, 100894.

L. V. Sigolaeva, T. V. Bulko, A. Y. Konyakhina, A. V. Kuzikov, R. A. Masamrekh, J. B. Max, M. Köhler, F. H. Schacher, D. V. Pergushov, V. V. Shumyantseva
Rational design of amphiphilic diblock copolymer/MWCNT surface modifiers and their application for direct electrochemical sensing of DNAExternal link
Polymers 2020, 12, 1514.

O. Sommerfeld, A. Medyukhina, S. Neugebauer, M. Ghait, S. Ulferts, A. Lupp, R. König, R. Wetzker, S. Schulz, M. T. Figge, M. Bauer, A. T. Press
Targeting complement C5a Receptor 1 for the treatment of immunosuppression in sepsisExternal link
Mol. Ther. 2020, DOI: 10.1016/j.ymthe.2020.1009.1008.

R. Takahashi, S. Miwa, C. Rössel, S. Fujii, J. H. Lee, F. H. Schacher, K. Sakurai
Polymersome formation induced by encapsulation of water-insoluble molecules within ABC triblock terpolymersExternal link
Polym. Chem. 2020, 11, 3446-3452.

J. Torralba, I. de la Arada, P. Carravilla, S. Insausti, E. Rujas, E. Largo, C. Eggeling, J. L. R. Arrondo, B. Apellániz, J. L. Nieva
Cholesterol constrains the antigenic configuration of the membrane-proximal neutralizing HIV-1 epitopeExternal link
ACS Infect. Dis. 2020, 6, 2155-2168.

D. Waithe, J. M. Brown, K. Reglinski, I. Diez-Sevilla, D. Roberts, C. Eggeling
Object detection networks and augmented reality for cellular detection in fluorescence microscopyExternal link
J. Cell Biol. 2020, 219, e201903166.

M. Wallert, L. Börmel, S. Lorkowski
Inflammatory diseases and vitamin E—What do we know and where do we go?External link
Mol. Nutr. Food Res. 2020, 2000097.

N. Arend, A. Pittner, A. Ramoji, A. S. Mondol, M. Dahms, J. Rüger, O. Kurzai, I. W. Schie, M. Bauer, J. Popp, U. Neugebauer
Detection and differentiation of bacterial and fungal infection of neutrophils from peripheral blood using raman spectroscopyExternal link
Anal. Chem. 2020, 92, 10560-10568.

G. Cinar, C. Englert, U. S. Schubert, I. Nischang
Salient features of medical nanoparticles in biological fluids from an analytical ultracentrifugeExternal link
Nanoscale 2020, DOI: 10.1039/D1030NR06153K.

A. Czapka, S. König, C. Pergola, C. Grune, K. Vougogiannopoulou, A.-L. Skaltsounis, D. Fischer, O. Werz
The indirubin derivative 6-bromoindirubin-3’-glycerol-oxime ether (6BIGOE) potently modulates inflammatory cytokine and prostaglandin release from human monocytes through GSK-3 interferenceExternal link
Biochem. Pharmacol. 2020, 180, 114170.

C. P. Dinh, A. Ville, K. Neukirch, G. Viault, V. Temml, A. Koeberle, O. Werz, D. Schuster, H. Stuppner, P. Richomme, J.-J. Helesbeux, D. Séraphin
Structure-based design, semi-synthesis and anti-inflammatory activity of tocotrienolic amides as 5-lipoxygenase inhibitorsExternal link
Eur. J. Med. Chem. 2020, 202, 112518.

P. Ernst, A. T. Press, M. Fischer, V. Günther, C. Gräfe, J. H. Clement, T. Ernst, U. S. Schubert, J. Wotschadlo, M. Lehmann, C. Enzensperger, M. Bauer, A. Hochhaus
Polymethine dye-functionalized nanoparticles for targeting CML stem cellsExternal link
Mol. Ther. Oncolytics 2020, 18, 372-381.

T. Götz, M. Dahms, J. Kirchhoff, C. Beleites, U. Glaser, J. A. Bohnert, M. W. Pletz, J. Popp, P. Schlattmann, U. Neugebauer
Automated and rapid identification of multidrug resistant Escherichia coli against the lead drugs of acylureidopenicillins, cephalosporins, and fluoroquinolones using specific Raman marker bandsExternal link
J. Biophotonics 2020, 13, e202000149.

M. Grube, V. Dinu, H. Lindemann, F. Pielenz, G. Festag, U. S. Schubert, T. Heinze, S. Harding, I. Nischang
Polysaccharide valproates: Structure - property relationships in solutionExternal link
Carbohydr. Polym. 2020, 246, 116652.

E. Jäger, S. Murthy, C. Schmidt, M. Hahn, S. Strobel, A. Peters, C. Stäubert, P. Sungur, T. Venus, M. Geisler, V. Radusheva, S. Raps, K. Rothe, R. Scholz, S. Jung, S. Wagner, M. Pierer, O. Seifert, W. Chang, I. Estrela-Lopis, N. Raulien, K. Krohn, N. Sträter, S. Hoeppener, T. Schöneberg, M. Rossol, U. Wagner
Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritisExternal link
Nat. Commun. 2020, 11, 4243.

P. M. Jordan, J. Gerstmeier, S. Pace, R. Bilancia, Z. Rao, F. Börner, L. Miek, Ó. Gutiérrez-Gutiérrez, V. Arakandy, A. Rossi, A. Ialenti, C. González-Estévez, B. Löffler, L. Tuchscherr, C. N. Serhan, O. Werz
Staphylococcus aureus-derived α-hemolysin evokes generation of specialized pro-resolving mediators promoting inflammation resolutionExternal link
Cell Reports 2020, 33, 108247.

M. Kühne, H. Lindemann, C. Grune, D. Schröder, Z. Cseresnyés, M. Godmann, A. Koschella, M. T. Figge, C. Eggeling, D. Fischer, T. Heinze, T. Heinzel
Biocompatible sulfated valproic acid-coupled polysaccharide-based nanocarriers with HDAC inhibitory activityExternal link
J. Control. Release 2020, DOI: 10.1016/j.jconrel.2020.1010.1006.

A. Lezov, A. Gubarev, T. Kaiser, W. Tobaschus, N. Tsvetkov, I. Nischang, U. S. Schubert, H. Frey, I. Perevyazko
“Hard” sphere behavior of “soft”, globular-like, hyperbranched polyglycerols – Extensive molecular hydrodynamic and light scattering studiesExternal link
Macromolecules 2020, DOI: 10.1021/acs.macromol.1020c01340.

S. Pace, O. Werz
Impact of androgens on inflammation-related lipid mediator biosynthesis in innate immune cellsExternal link
Front. Immunol. 2020, 11, DOI: 10.3389/fimmu.2020.01356.

S. Rahimi, S. Stumpf, O. Grimm, F. H. Schacher, U. S. Schubert, S. Schubert
Dual photo- and pH-responsive spirooxazine-functionalized dextran nanoparticlesExternal link
Biomacromolecules 2020, 21, 3620-3630.

T. Ritschel, K. Lehmann, M. Brunzel, J. Vitz, I. Nischang, U. S. Schubert, K. U. Totsche
Well-defined poly(ethylene glycol) polymers as non-conventional reactive tracers of colloidal transport in porous mediaExternal link
J. Colloid Interface Sci. 2020, DOI: 10.1016/j.jcis.2020.1009.1056.

K. Scheuer, D. Bandelli, C. Helbing, C. Weber, J. Alex, J. B. Max, A. Hocken, O. Stranik, L. Seiler, F. Gladigau, U. Neugebauer, F. H. Schacher, U. S. Schubert, K. D. Jandt
Self-assembly of copolyesters into stereocomplex crystallites tunes the properties of polyester nanoparticlesExternal link
Macromolecules 2020, 53, 8340-8351.

F. Schmidt, A. Thywißen, M. Goldmann, C. Cunha, Z. Cseresnyés, H. Schmidt, M. Rafiq, S. Galiani, M. H. Gräler, G. Chamilos, J. F. Lacerda, A. Campos, C. Eggeling, M. T. Figge, T. Heinekamp, S. G. Filler, A. Carvalho, A. A. Brakhage
Flotillin-dependent membrane microdomains are required for functional phagolysosomes against fungal infectionsExternal link
Cell Reports 2020, 32, 108017.

T. Schuett, J. Kimmig, S. Zechel, U. S. Schubert
Automated polymer purification using dialysisExternal link
Polymers 2020, 12, 2095.

M. Sittig, J. C. Tom, J. Elter, F. H. Schacher, B. Dietzek
Quinoline photobasicity – Investigation within water-soluble light-responsive copolymersExternal link
Chem. Eur. J. 2020, DOI: 10.1002/chem.202003815.

J. Zhang, B. Farias-Mancilla, I. Kulai, S. Hoeppener, B. Lonetti, S. Prévost, J. Ulbrich, M. Destarac, O. Colombani, U. S. Schubert, C. Guerrero-Sanchez, S. Harrisson
Effect of hydrophilic monomer distribution on self-assembly of a pH-responsive copolymer: Spheres, worms and vesicles from a single copolymer compositionExternal link
Angew. Chem. Int. Ed. 2020, DOI: 10.1002/anie.202010501.

D. Bandelli, I. Muljajew, K. Scheuer, J. B. Max, C. Weber, F. H. Schacher, K. D. Jandt, U. S. Schubert
Copolymerization of caprolactone isomers to obtain nanoparticles with constant hydrophobicity and tunable crystallinityExternal link
Macromolecules 2020, DOI: 10.1021/acs.macromol.0c00486.

B. Böttcher, B. Hoffmann, E. Garbe, T. Weise, Z. Cseresnyés, P. Brandt, S. Dietrich, D. Driesch, M. T. Figge, S. Vylkova
The transcription factor Stp2 is important for Candida albicans biofilm establishment and sustainabilityExternal link
Front. Microbiol. 2020, 11, 794.

G. Cinar, C. Englert, M. Lehmann, I. Nischang
In situ, quantitative assessment of multifunctional nanoscale drug delivery systems in human serumExternal link
Anal. Chem. 2020, 92, 7932-7939.

Z. Cseresnyes, M. I. A. Hassan, H.-M. Dahse, K. Voigt, M. T. Figge
Quantitative impact of cell membrane fluorescence labeling on phagocytosis measurements in confrontation assaysExternal link
Front. Microbiol. 2020, DOI: 10.3389/fmicb.2020.01193.

M. A. De Jesús-Téllez, D. M. Sánchez-Cerrillo, P. Quintana-Owen, U. S. Schubert, D. Contreras-López, C. Guerrero-Sánchez
Kinetic investigations of quaternization reactions of poly[2-(dimethylamino)ethyl methacrylate] with diverse alkyl halidesExternal link
Macromol. Chem. Phys. 2020, 221, 1900543.

A. Medyukhina, M. Blickensdorf, Z. Cseresnyés, N. Ruef, J. V. Stein, M. T. Figge
Dynamic spherical harmonics approach for shape classification of migrating cells
Sci. Rep. 2020, 10, 6072.

P. Wei, G. Gangapurwala, D. Pretzel, L. Wang, S. Schubert, J. C. Brendel, U. S. Schubert
Tunable nanogels by host–guest interaction with carboxylate pillar[5]arene for controlled encapsulation and release of doxorubicinExternal link
Nanoscale 2020, 12, 13595-13605.

A. Barbotin, I. Urbančič, S. Galiani, C. Eggeling, M. Booth, E. Sezgin
z-STED imaging and spectroscopy to investigate nanoscale membrane structure and dynamicsExternal link
Biophys. J. 2020, 118, 2448-2457.

A. A. Womiloju, C. Höppener, U. S. Schubert, S. Hoeppener
Microwave-assisted synthesis of core–shell nanoparticles - Insights into the growth of different geometriesExternal link
Part. Part. Syst. Charact. 2020, 2000019.

T. A. Stanly, M. Fritzsche, S. Banerji, D. Shrestha, F. Schneider, C. Eggeling, D. G. Jackson
The cortical actin network regulates avidity-dependent binding of hyaluronan by the Lymphatic Vessel Endothelial receptor LYVE-1External link
J. Biol. Chem. 2020, DOI: 10.1074/jbc.RA1119.011992.

B. Shkodra-Pula, A. Vollrath, U. S. Schubert, S. Schubert
Polymer-based nanoparticles for biomedical applicationsExternal link
in Frontiers of Nanoscience, Vol. 16 (Eds.: W. J. Parak, N. Feliu), Elsevier, 2020, pp. 233-252.

B. Shkodra-Pula, C. Kretzer, P. Jordan, P. Klemm, A. Koeberle, D. Pretzel, E. Banoglu, S. Lorkowski, M. Wallert, S. Hoeppener, S. Stumpf, A. Vollrath, S. Schubert, O. Werz, U. S. Schubert
Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivityExternal link
J. Nanobiotechnol. 2020, DOI: 10.21203/rs.21203.rs-15745/v21201.

E. Sezgin, D. Carugo, I. Levental, E. Stride, C. Eggeling
Creating supported plasma membrane bilayers using acoustic pressureExternal link
bioRxiv 2020, DOI: 10.1101/2020.1101.1120.912840.

F. Schneider, P. Hernandez-Varas, C. Lagerholm, D. Shrestha, E. Sezgin, J. Roberti, G. Ossato, F. Hecht, C. Eggeling, I. Urbančič
High photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopyExternal link
J. Phys. D: Appl. Phys. 2020, 53, 64003.

F. Richter, L. Martin, K. Leer, E. Moek, F. Hausig, J. C. Brendel, A. Traeger
Tuning of endosomal escape and gene expression by functional groups, molecular weight and transfection medium: a structure–activity relationship studyExternal link
J. Mater. Chem. B 2020, DOI: 10.1039/d1030tb00340a.

T. Hanke, S.-Y. Cheung, W. Kilu, J. Heering, X. Ni, V. Planz, S. Schierle, G. Faudone, M. Friedrich, M. Wanior, O. Werz, M. Windbergs, E. Proschak, M. Schubert-Zsilavecz, A. Chaikuad, S. Knapp, D. Merk
A selective modulator of peroxisome proliferator-activated receptor γ with an unprecedented binding modeExternal link
J. Med. Chem. 2020, Doi: 10.1021/acs.jmedchem.1029b01786.

M. Dirauf, C. Grune, C. Weber, U. S. Schubert, D. Fischer
Poly(ethylene glycol) or poly(2-ethyl-2-oxazoline) – A systematic comparison of PLGA nanoparticles from the bottom upExternal link
Eur. Polym. J. 2020, 134, 109801.

M. Dirauf, A. Erlebach, C. Weber, S. Hoeppener, J. R. Buchheim, M. Sierka, U. S. Schubert
Block copolymers composed of PEtOx and polyesteramides based on glycolic acid, L-valine, and L-isoleucineExternal link
Macromolecules 2020, DOI: 10.1021/acs.macromol.1020c00282.

M. G. Chini, A. Giordano, M. Potenza, S. Terracciano, K. Fischer, M. C. Vaccaro, E. Colarusso, I. Bruno, R. Riccio, A. Koeberle, O. Werz, G. Bifulco
Targeting mPGES-1 by a combinatorial approach: Identification of the aminobenzothiazole scaffold to suppress PGE2 levelsExternal link
ACS Med. Chem. Lett. 2020, DOI: 10.1021/acsmedchemlett.1029b00618.

P. Carravilla, J. L. Nieva, C. Eggeling
Fluorescence microscopy of the HIV-1 envelopeExternal link
Viruses 2020, 12, 348.

A. Barbotin, I. Urbančič, S. Galiani, C. Eggeling, M. Booth
Background reduction in STED-FCS using coherent-hybrid STEDExternal link
bioRxiv 2020, DOI: 10.1101/2020.1101.1106.895243.

J. Alex, K. González, T. Kindel, P. Bellstedt, C. Weber, T. Heinekamp, T. Orasch, C. Guerrero-Sanchez, U. S. Schubert, A. A. Brakhage
Caspofungin functionalized polymethacrylates with antifungal propertiesExternal link
Biomacromolecules 2020, DOI: 10.1021/acs.biomac.0c00096.

H. Lindemann, M. Kühne, C. Grune, P. Warncke, S. Hofmann, A. Koschella, M. Godmann, D. Fischer, T. Heinzel, T. Heinze
Polysaccharide nanoparticles bearing HDAC inhibitor as nontoxic nanocarrier for drug deliveryExternal link
Macromol. Biosci. 2020, 2000039.

M. Grube, I. Perevyazko, T. Heinze, U. S. Schubert, I. Nischang,
Revisiting very disperse macromolecule populations in hydrodynamic and light scattering studies of sodium carboxymethyl cellulosesExternal link
Carbohydr. Polym. 2020, 229, 115452.

S. C. Koeberle, A. Gollowitzer, J. Laoukili, O. Kranenburg, O. Werz, A. Koeberle, A. P. Kipp
Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanismsExternal link
Redox Biology 2020, 28, 101388.

I. Muljajew, A. Erlebach, C. Weber, J. R. Buchheim, M. Sierka, U. S. Schubert
A polyesteramide library from dicarboxylic acids and 2,2′-bis(2-oxazoline): synthesis, characterization, nanoparticle formulation and molecular dynamics simulationsExternal link
Polym. Chem. 2020, 11, 112-124.

M. Werner, S. Pace, A. Czapka, P. M. Jordan, J. Gerstmeier, A. Koeberle, O. Werz
Communication between human macrophages and epithelial cancer cell lines dictates lipid mediator biosynthesisExternal link
Cell. Mol. Life Sci. 2020, DOI: 10.1007/s00018-00019-03413-w.

T. Wloka, S. Czich, M. Kleinsteuber, E. Moek, C. Weber, M. Gottschaldt, K. Liefeith, U. S. Schubert
Microfabrication of 3D-hydrogels via two-photon polymerization of poly(2-ethyl-2-oxazoline) diacrylatesExternal link
Eur. Polym. J. 2020, 122, 109295.

A. M. Ali, T. Deckert-Gaudig, M. Egiza, V. Deckert, T. Yoshitake
Near- and far-field Raman spectroscopic studies of nanodiamond composite films deposited by coaxial arc plasmaExternal link
Appl. Phys. Lett. 2020, 116, 041601.

C. Chen, F. Richter, C. Guerrero-Sanchez, A. Traeger, U. S. Schubert, A. Feng, S. H. Thang
Cell-penetrating, peptide-based RAFT agent for constructing penetration enhancersExternal link
ACS Macro Letters 2020, 9, 260-265.

C. Cokca, L. Zartner, I. Tabujew, D. Fischer, K. Peneva
Incorporation of indole significantly improves the transfection efficiency of guanidinium-containing poly(methacrylamide)sExternal link
Macromol. Rapid Commun. 2020, 41, 2070012.

J. A. Czaplewska, G. Gangapurwala, A. Vollrath, M. Pröhl, T. Majdanski, D. Pretzel, S. Hoeppener, U. S. Schubert, M. Gottschaldt
Synthesis of a fructose decorated PAGE-b-PEG-b-PLGA polymer with subsequent formulation of nanoparticlesExternal link
Colloids Surf. A Physicochem. Eng. Asp. 2020, 124701.

S. Deinhardt-Emmer, K. Rennert, E. Schicke, Z. Cseresnyés, M. Windolph, S. Nietzsche, R. Heller, F. Siwczak, K. F. Haupt, S. Carlstedt, M. Schacke, M. T. Figge, C. Ehrhardt, B. Löffler, A. S. Mosig
Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip modelExternal link
Biofabrication 2020, 12, 025012.

A. Erlebach, I. Muljajew, M. Chi, C. Bückmann, C. Weber, U. S. Schubert, M. Sierka
Predicting solubility of small molecules in macromolecular compounds for nanomedicine application from atomistic simulationsExternal link
Adv. Theory Simul. 2020, DOI: 10.1002/adts.202000001.

E. Gardey, F. H. Sobotta, S. Hoeppener, T. Bruns, A. Stallmach, J. C. Brendel
Influence of core cross-linking and shell composition of polymeric micelles on immune response and their interaction with human monocytesExternal link
Biomacromolecules 2020, DOI: 10.1021/acs.biomac.9b01656.

M. Gericke, P. Schulze, T. Heinze
Nanoparticles based on hydrophobic polysaccharide derivatives—formation principles, characterization techniques, and biomedical applicationsExternal link
Macromol. Biosci. 2020, 1900415.

M. Grube, G. Cinar, U. S. Schubert, I. Nischang
Incentives of using the hydrodynamic invariant and sedimentation parameter for the study of naturally- and synthetically-based macromolecules in solutionExternal link
Polymers 2020, 12, 277.

K. Hiesinger, A. Schott, J. S. Kramer, R. Blöcher, F. Witt, S. K. Wittmann, D. Steinhilber, D. Pogoryelov, J. Gerstmeier, O. Werz, E. Proschak
Design of dual inhibitors of soluble epoxide hydrolase and LTA4 hydrolaseExternal link
ACS Med. Chem. Lett. 2020, 11, 298-302.

C. Höppener, F. H. Schacher, V. Deckert
Multimodal characterization of resin embedded and sliced polymer nanoparticles by means of tip-enhanced raman spectroscopy and force–distance curve based atomic force microscopyExternal link
Small 2020, 1907418.

J. Hübner, T. Deckert-Gaudig, J. Glorian, V. K. Deckert, D. Spitzer
Surface characterization of nanoscale co-crystals enabled through tip enhanced raman spectroscopyExternal link
Nanoscale 2020, DOI: 10.1039/D1030NR00397B.

S. M. A. S. Keshk, A. A. El-Zahhar, Q. A. Alsulami, M. Jaremko, S. Bondock, T. Heinze
Synthesis, characterization and ampyrone drug release behavior of magnetite nanoparticle/2,3-dialdehyde cellulose-6-phosphate compositeExternal link
Cellulose 2020, 27, 1603-1618.

A. Koschella, C.-Y. Chien, T. Iwata, M. S. Thonhofer, T. M. Wrodnigg, T. Heinze
All sugar based cellulose derivatives synthesized by azide–alkyne click chemistryExternal link
Macromol. Chem. Phys. 2020, 221, 1900343.

G. Lauro, S. Terracciano, V. Cantone, D. Ruggiero, K. Fischer, S. Pace, O. Werz, I. Bruno, G. Bifulco
A combinatorial virtual screening approach driving the synthesis of 2,4-thiazolidinedione-based molecules as new dual mPGES-1/5-LO inhibitorsExternal link
ChemMedChem 2020, 15, 481-489.

V. D. Lechuga-Islas, G. Festag, M. Rosales-Guzmán, O. E. Vega-Becerra, R. Guerrero-Santos, U. S. Schubert, C. Guerrero-Sánchez
Quasi-block copolymer design of quaternized derivatives of poly(2-(dimethylamino)ethyl methacrylate): Investigations on thermo-induced self-assemblyExternal link
Eur. Polym. J. 2020, 124, 109457.

E. Matuszyk, E. Sierka, M. Rodewald, H. Bae, T. Meyer, E. Kus, S. Chlopicki, M. Schmitt, J. Popp, M. Baranska
Differential response of liver sinusoidal endothelial cells and hepatocytes to oleic and palmitic acid revealed by Raman and CARS imagingExternal link
Biochim. Biophys. Acta Mol. Basis Disease 2020, 1866, 165763.

J. B. Max, P. J. Mons, J. C. Tom, F. H. Schacher
Double hydrophilic poly(ethylene oxide)-block-poly(dehydroalanine) block copolymers: Comparison of two different synthetic routesExternal link
Macromol. Chem. Phys. 2020, 221, 1900383.

A. Olgac, A. Carotti, C. Kretzer, S. Zergiebel, A. Seeling, U. Garscha, O. Werz, A. Macchiarulo, E. Banoglu
Discovery of novel 5-lipoxygenase-activating protein (FLAP) inhibitors by exploiting a multistep virtual screening protocolExternal link
J. Chem. Inf. Model. 2020, 60, 1737-1748.

Z. Rao, P. M. Jordan, Y. Wang, D. Menche, S. Pace, J. Gerstmeier, O. Werz
Differential role of vacuolar (H+)-ATPase in the expression and activity of cyclooxygenase-2 in human monocytesExternal link
Biochem. Pharmacol. 2020, 175, 113858.

V. V. Shumyantseva, T. V. Bulko, A. V. Kuzikov, R. A. Masamrekh, A. Y. Konyakhina, I. Romanenko, J. B. Max, M. Köhler, A. A. Gilep, S. A. Usanov, D. V. Pergushov, F. H. Schacher, L. V. Sigolaeva
All-electrochemical nanocomposite two-electrode setup for quantification of drugs and study of their electrocatalytical conversion by cytochromes P450External link
Electrochimica Acta 2020, 336, 135579.

P. Singh, T. Deckert-Gaudig, Z. Zhang, V. Deckert
Plasmon induced deprotonation of 2-mercaptopyridineExternal link
Analyst 2020, 145, 2106-2110.

M. Sittig, B. Schmidt, H. Görls, T. Bocklitz, M. Wächtler, S. Zechel, M. D. Hager, B. Dietzek
Fluorescence upconversion by triplet-triplet annihilation in all-organic poly(methacrylate)-terpolymersExternal link
Phys. Chem. Chem. Phys. 2020, 22, 4072-4079.

R. Takahashi, S. Miwa, F. H. Sobotta, J. H. Lee, S. Fujii, N. Ohta, J. C. Brendel, K. Sakurai
Unraveling the kinetics of the structural development during polymerization-induced self-assembly: decoupling the polymerization and the micelle structureExternal link
Polym. Chem. 2020, 11, 1514-1524.

A. Traeger, S. Voelker, B. Shkodra-Pula, C. Kretzer, S. Schubert, M. Gottschaldt, U. S. Schubert, O. Werz
Improved bioactivity of the natural product 5-lipoxygenase inhibitor hyperforin by encapsulation into polymeric nanoparticlesExternal link
Mol. Pharm. 2020, 17, 810-816.

P. Wei, J. A. Czaplewska, L. Wang, S. Schubert, J. C. Brendel, U. S. Schubert
Straightforward access to glycosylated, acid sensitive nanogels by host–guest interactions with sugar-modified pillar[5]arenesExternal link
ACS Macro Letters 2020, 9, 540-545.

P. Wei, F. H. Sobotta, C. Kellner, D. Bandelli, S. Hoeppener, S. Schubert, J. C. Brendel, U. S. Schubert
Degradable polycaprolactone nanoparticles stabilized via supramolecular host–guest interactions with pH-responsive polymer-pillar[5]arene conjugatesExternal link
Polym. Chem. 2020, 11, 1985-1997.

F. Wendler, J. C. Tom, M. Sittig, P. Biehl, B. Dietzek, F. H. Schacher
Block copolymers featuring highly photostable photoacids based on vinylnaphthol: Synthesis and self-assemblyExternal link
Macromol. Rapid Commun. 2020, 41, 1900607.
2019
N. Köse-Vogel, S. Stengel, E. Gardey, T. Kirchberger-Tolstik, P. A. Reuken, A. Stallmach, T. Bruns
Transcriptional suppression of the NLRP3 inflammasome and cytokine release in primary macrophages by low-dose anthracyclinesExternal link
Cells 2019, 9, 79.

G. Creusen, A. Roshanasan, J. Garcia Lopez, K. Peneva, A. Walther
Bottom-up design of model network elastomers and hydrogels from precise star polymersExternal link
Polym. Chem. 2019, 10, 3740-3750.

F. Wendler, J. C. Tom, F. H. Schacher
Synthesis and self-assembly of photoacid-containing block copolymers based on 1-naphtholExternal link
Polym. Chem. 2019, 10, 5602-5616.

D. Bandelli, J. Alex, C. Weber, U. S. Schubert
Polyester stereocomplexes beyond PLA: Could synthetic opportunities revolutionize established material blending?External link
Macromol. Rapid Commun. 2019, 1900560.

T. Chakraborty, M. K. Driscoll, E. Jeffery, M. M. Murphy, P. Roudot, B.-J. Chang, S. Vora, W. M. Wong, C. D. Nielson, H. Zhang, V. Zhemkov, C. Hiremath, E. D. De La Cruz, Y. Yi, I. Bezprozvanny, H. Zhao, R. Tomer, R. Heintzmann, J. P. Meeks, D. K. Marciano, S. J. Morrison, G. Danuser, K. M. Dean, R. FiolkaLight-sheet microscopy of cleared tissues with isotropic, subcellular resolutionExternal link
Nat. Meth. 2019, 16, 1109-1113.

C. Favard, J. Chojnacki, P. Merida, N. Yandrapalli, J. Mak, C. Eggeling, D. Muriaux
HIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assemblyExternal link
Sci. Adv. 2019, 5, eaaw8651.

E. Romp, V. Arakandy, J. Fischer, C. Wolz, A. Siegmund, B. Löffler, L. Tuchscherr, O. Werz, U. Garscha
Exotoxins from Staphylococcus aureus activate 5-lipoxygenase and induce leukotriene biosynthesisExternal link
Cell. Mol. Life Sci. 2019, DOI: 10.1007/s00018-00019-03393-x.

M. Rosales-Guzmán, O. Pérez-Camacho, C. Guerrero-Sánchez, S. Harrisson, R. Torres-Lubián, J. Vitz, U. S. Schubert, E. Saldívar-Guerra
Semiautomated parallel RAFT copolymerization of isoprene with glycidyl methacrylateExternal link
ACS Comb. Sci. 2019, 21, 771-781.

F. Wendler, M. Sittig, J. C. Tom, B. Dietzek, F. H. Schacher
Polymeric photoacids based on naphthols - Design criteria, photostability, and light-mediated releaseExternal link
Chem. Eur. J. 2019, DOI: 10.1002/chem.201903819.

R. Meyer, S. Trautmann, K. Rezaei, A. George, A. Turchanin, V. Deckert
Synergy of photoinduced force microscopy and tip-enhanced Raman spectroscopy—A correlative study on MoS2External link
ACS Photonics 2019, 6, 1191-1198.

J. B. Max, D. V. Pergushov, L. V. Sigolaeva, F. H. Schacher
Polyampholytic graft copolymers based on polydehydroalanine (PDha) – synthesis, solution behavior and application as dispersants for carbon nanotubesExternal link
Polym. Chem. 2019, 10, 3006-3019.

J. Langer, D. Jimenez de Aberasturi, J. Aizpurua, R. A. Alvarez-Puebla, B. Auguié, J. J. Baumberg, G. C. Bazan, S. E. J. Bell, A. Boisen, A. G. Brolo, J. Choo, D. Cialla-May, V. Deckert, L. Fabris, K. Faulds, F. J. García de Abajo, R. Goodacre, D. Graham, A. J. Haes, C. L. Haynes, C. Huck, T. Itoh, M. Käll, J. Kneipp, N. A. Kotov, H. Kuang, E. C. Le Ru, H. K. Lee, J.-F. Li, X. Y. Ling, S. Maier, T. Mayerhoefer, M. Moskovits, K. Murakoshi, J.-M. Nam, S. Nie, Y. Ozaki, I. Pastoriza-Santos, J. Perez-Juste, J. Popp, A. Pucci, S. Reich, B. Ren, G. C. Schatz, T. Shegai, S. Schlücker, T. Li-Lin, K. G. Thomas, Z.-Q. Tian, R. P. Van Duyne, T. Vo-Dinh, Y. Wang, K. A. Willets, C. Xu, H. Xu, Y. Xu, Y. S. Yamamoto, B. Zhao, L. M. Liz-MarzánPresent and future of surface enhanced Raman scatteringExternal link
ACS Nano 2019, DOI: 10.1021/acsnano.1029b04224.

J. Ernst, M. Klinger-Strobel, J. Thamm, O. Makarewicz, M. Pletz, D. Fischer
Breaking the biofilm barrier: The role of stabilizers in biofilm penetration and pulmonary antibiotic delivery by polymer nanoparticles
Pharmazeutische Industrie 2019, 81, 248-255.

J. K. Elter, P. Biehl, M. Gottschaldt, F. H. Schacher
Core-crosslinked worm-like micelles from polyether-based diblock terpolymersExternal link
Polym. Chem. 2019, DOI: 10.1039/C1039PY01054H.

V. H. Bac, B. S. Paulsen, L. V. Truong, A. Koschella, T. C. Trinh, C. W. Wold, S. Yogarajah, T. Heinze
Neutral polysaccharide from the leaves of pseuderanthemum carruthersii: Presence of 3-O-methyl galactose and anti-inflammatory activity in LPS-stimulated RAW 264.7 cellsExternal link
Polymers 2019, 11, 1219.

L. Applová, J. Karlíčková, P. Warncke, K. Macáková, M. Hrubša, M. Macháček, V. Tvrdý, D. Fischer, P. Mladěnka
4-Methylcatechol, a flavonoid metabolite with potent antiplatelet effectsExternal link
Mol. Nutr. Food Res. 2019, 63, 1900261.

I. Perevyazko, A. Lezov, A. S. Gubarev, E. Lebedeva, G. Festag, C. Guerrero-Sanchez, N. Tsvetkov, U. S. Schubert
Structure-property relationships via complementary hydrodynamic approaches: Poly(2-(dimethylamino)ethyl methacrylate)sExternal link
Polymer 2019, 182, 121828.

L. V. Sigolaeva, T. V. Bulko, M. S. Kozin, W. Zhang, M. Köhler, I. Romanenko, J. Yuan, F. H. Schacher, D. V. Pergushov, V. V. Shumyantseva
Long-term stable poly(ionic liquid)/MWCNTs inks enable enhanced surface modification for electrooxidative detection and quantification of dsDNAExternal link
Polymer 2019, 168, 95-103.

C. St Thomas, C. N. Muñoz López, E. J. Jiménez Regalado, M. A. de Jesús Tellez, G. Festag, U. S. Schubert, C. Guerrero-Sánchez
Preparation of hydrophobically modified associating multiblock copolymers via a one-pot aqueous RAFT polymerizationExternal link
Polym. Chem. 2019, DOI: 10.1039/C1039PY01311C.

M. Wang, J. Zhang, C. Guerrero-Sanchez, U. S. Schubert, A. Feng, S. H. Thang
Enzyme degassing for oxygen-sensitive reactions in open vessels of an automated parallel synthesizer: RAFT polymerizationsExternal link
ACS Comb. Sci. 2019, 21, 643-649.

M. Wallert, M. Ziegler, X. Wang, A. Maluenda, X. Xu, M. L. Yap, R. Witt, C. Giles, S. Kluge, M. Hortmann, J. Zhang, P. Meikle, S. Lorkowski, K. Peterα-Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injuryExternal link
Redox Biology 2019, 26, 101292.

H. L. Cao, X. Y. Liu, K. D. Jandt
The action-network of nanomaterials External linkin "On the issue of transparency and reproducibility in nanomedicine"External link
Nat. Nanotechn. 2019, 14, 629-635.

D. Bandelli, C. Weber, U. S. Schubert
Strontium isopropoxide: A highly active catalyst for the ring-opening polymerization of lactide and various lactonesExternal link
Macromol. Rapid Commun. 2019, 1900306.

Z. Rao, S. Pace, P. M. Jordan, R. Bilancia, F. Troisi, F. Börner, N. Andreas, T. Kamradt, D. Menche, A. Rossi, C. N. Serhan, J. Gerstmeier, O. WerzVacuolar (H+)-ATPase critically regulates specialized proresolving mediator pathways in human M2-like monocyte-derived macrophages and has a crucial role in resolution of inflammationExternal link
J. Immunol. 2019, 203, 1031-1043.

H. Würfel, M. Kayser, T. HeinzeNon-aqueous solvent for efficient dissolution of polygalacturonic acidExternal link
Carbohydr. Polym. 2019, 207, 791-795.

H. Würfel, M. Kayser, T. HeinzeTrimethylsilylation of Polygalacturonic AcidExternal link
Macromol. Chem. Phys. 2019, 220, 1900002.

M. Kostag, M. Gericke, T. Heinze, O. A. El Seoud
Twenty-five years of cellulose chemistry: innovations in the dissolution of the biopolymer and its transformation into esters and ethersExternal link
Cellulose 2019, 26, 139-184.

C. Pinon-Balderrama, C. Leyva-Porras, R. Olayo-Valles, J. Revilla-Vazquez, U. S. Schubert, C. Guerrero-Sanchez, J. Bonilla-CruzSelf-assembly investigations of sulfonated poly(methyl methacrylate-block-styrene) diblock copolymer thin filmsExternal link
Adv. Polym. Technol. 2019, 2019, 11.

A. Sierra-Fernandez, S. C. De la Rosa-García, R. Yañez-Macías, C. Guerrero-Sanchez, L. S. Gomez-Villalba, S. Gómez-Cornelio, M. E. Rabanal, U. S. Schubert, R. Fort, P. QuintanaSol–gel synthesis of Mg(OH)2 and Ca(OH)2 nanoparticles: a comparative study of their antifungal activity in partially quaternized p(DMAEMA) nanocomposite filmsExternal link
J. Sol-Gel Sci. Technol. 2019, 89, 310-321.

M. Zink, K. Hotzel, U. S. Schubert, T. Heinze, D. FischerAmino Acid–Substituted Dextran-Based Non-Viral Vectors for Gene DeliveryExternal link
Macromol. Biosci. 2019, 19, 1900085.

J. Gerstmeier, C. Kretzer, S. Di Micco, L. Miek, H. Butschek, V. Cantone, R. Bilancia, R. Rizza, F. Troisi, N. Cardullo, C. Tringali, A. Ialenti, A. Rossi, G. Bifulco, O. Werz, S. PaceNovel benzoxanthene lignans that favorably modulate lipid mediator biosynthesis: A promising pharmacological strategy for anti-inflammatory therapyExternal link
Biochem. Pharmacol. 2019, 165, 263-274.

J. Gerstmeier, J. Seegers, F. Witt, B. Waltenberger, V. Temml, J. M. Rollinger, H. Stuppner, A. Koeberle, D. Schuster, O. Werz
Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator BiosynthesisExternal link
Frontiers in Pharmacology 2019, 10.

S. Shekfeh, B. Çalışkan, K. Fischer, T. Yalçın, U. Garscha, O. Werz, E. BanogluA Multi‐step Virtual Screening Protocol for the Identification of Novel Non‐acidic Microsomal Prostaglandin EExternal link₂ Synthase‐1 (mPGES‐1) InhibitorsExternal link
ChemMedChem 2019, 14, 273-281.

M. Wallert, J. Bauer, S. Kluge, L. Schmölz, Y.-C. Chen, M. Ziegler, A. K. Searle, A. Maxones, M. Schubert, M. Thürmer, H. Pein, A. Koeberle, O. Werz, M. Birringer, K. Peter, S. LorkowskiThe vitamin E derivative garcinoic acid from External linkGarcinia kola nut seeds attenuates the inflammatory responseExternal link
Redox Biology 2019, 24, 101166.

M. Reifarth, W. Müller, B. Shkodra-Pula, H. Görls, U. S. Schubert, R. Heintzmann, S. HoeppenerElectron density of polymeric nanoparticles determined by image processing of transmission electron micrographs: Insights into heavy metal staining processesExternal link
Particle & Particle Systems Characterization 2019, 1800324.

M. Sahn, C. Weber, U. S. Schubert
Poly(2-oxazoline)-containing triblock copolymers: Synthesis and applicationsExternal link
Polym. Rev. 2019, doi: 10.1080/15583724.2018.1496930.

P. Wei, G. Gangapurwala, D. Pretzel, M. N. Leiske, L. Wang, S. Hoeppener, S. Schubert, J. C. Brendel, U. S. Schubert
Smart pH-sensitive nanogels for controlled release in an acidic environmentExternal link
Biomacromolecules 2019, 20, 130-140.

M. Werner, P. M. Jordan, E. Romp, A. Czapka, Z. Rao, C. Kretzer, A. Koeberle, U. Garscha, S. Pace, H.-E. Claesson, C. N. Serhan, O. Werz, J. Gerstmeier
Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolomeExternal link
The FASEB Journal 2019, doi: 10.1096/fj.201802509R.

L. Wondraczek, G. Pohnert, F. H. Schacher, A. Köhler, M. Gottschaldt, U. S. Schubert, K. Küsel, A. A. Brakhage
Artificial microbial arenas: Materials for observing and manipulating microbial consortiaExternal link
Adv. Mater. 2019, 31, 1900284.

B. Shkodra-Pula, C. Grune, A. Traeger, A. Vollrath, S. Schubert, D. Fischer, U. S. Schubert
Effect of surfactant on the size and stability of PLGA nanoparticles encapsulating a protein kinase C inhibitorExternal link
Int. J. Pharm. 2019, 566, 756-764.

C. Reichardt, S. Monro, F. H. Sobotta, K. L. Colón, T. Sainuddin, M. Stephenson, E. Sampson, J. Roque, H. Yin, J. C. Brendel, C. G. Cameron, S. McFarland, B. Dietzek
Predictive strength of photophysical measurements for in vitro photobiological activity in a series of Ru(II) polypyridyl complexes derived from π-extended ligandsExternal link
Inorg. Chem. 2019, 58, 3156-3166.

H. Qiu, Z. Yang, M. Köhler, J. Ling, F. H. Schacher
Synthesis and solution self-assembly of poly(1,3-dioxolane)External link
Macromolecules 2019, 52, 3359-3366.

N. Engel, M. Dirauf, S. Seupel, M. N. Leiske, S. Schubert, U. S. Schubert
Utilization of 4-(trifluoromethyl)benzenesulfonates as counter ions tunes the initiator efficiency of sophisticated initiators for the preparation of well-defined poly(2-oxazoline)sExternal link
Macromol. Rapid Commun. 2019, 40, 1900094.

N. Al Nakeeb, I. Nischang, B. V. K. J. Schmidt
Tannic acid-mediated aggregate stabilization of poly(N-vinylpyrrolidone)-b-poly(oligo (ethylene glycol) methyl ether methacrylate) double hydrophilic block copolymersExternal link
Nanomaterials 2019, 9, 662.

M. Maurer, M. S. Gresnigt, A. Last, T. Wollny, F. Berlinghof, R. Pospich, Z. Cseresnyes, A. Medyukhina, K. Graf, M. Gröger, M. Raasch, F. Siwczak, S. Nietzsche, I. D. Jacobsen, M. T. Figge, B. Hube, O. Huber, A. S. Mosig
A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studiesExternal link
Biomaterials 2019, 220, 119396.

M. I. A. Hassan, Z. Cseresnyes, N. Al-Zaben, H.-M. Dahse, R. J. Vilela de Oliveira, G. Walther, K. Voigt, M. T. Figge
The geographical region of origin determines the phagocytic vulnerability of Lichtheimia strainsExternal link
Environ. Microbiol., DOI: 10.1111/1462-2920.14752.

D. Bandelli, J. Alex, C. Helbing, N. Ueberschaar, H. Görls, P. Bellstedt, C. Weber, K. D. Jandt, U. S. Schubert
Poly(ethylglycolide): A well-defined polyester matching the hydrophilic hydrophobic balance of PLAExternal link
Polym. Chem. 2019, DOI: 10.1039/c1039py00875f.

I. Tabujew, C. Cokca, L. Zartner, U. S. Schubert, I. Nischang, D. Fischer, K. Peneva
The influence of gradient and statistical arrangements of guanidinium or primary amine groups in poly(methacrylate) copolymers on their DNA binding affinityExternal link
Journal of Materials Chemistry B 2019, DOI: 10.1039/c9tb01269a.

A. Barbotin, S. Galiani, I. Urbančič, C. Eggeling, M. J. Booth
Adaptive optics allows STED-FCS measurements in the cytoplasm of living cellsExternal link
Optics Express 2019, 27, 23378-23395.

T. Klein, F. V. Gruschwitz, S. Rogers, S. Hoeppener, I. Nischang, J. C. Brendel
The influence of directed hydrogen bonds on the self-assembly of amphiphilic polymers in waterExternal link
J. Colloid Interface Sci. 2019, 557, 488-497.

M. E. Mikhailova, A. S. Senchukova, A. A. Lezov, A. S. Gubarev, A.-K. Trützschler, U. S. Schubert, N. V. Tsvetkov
Stabilization of Silver Nanoparticles by Cationic Aminoethyl Methacrylate Copolymers in Aqueous Media—Effects of Component Ratios and Molar Masses of CopolymersExternal link
Polymers 2019, 11, 1647.

M. Raasch, E. Fritsche, A. Kurtz, M. Bauer, A. S. Mosig
Microphysiological systems meet hiPSC technology - New tools for disease modeling of liver infections in basic research and drug developmentExternal link
Adv. Drug Delivery Rev. 2019, 140, 51-67.

E. Rossegger, F. Pirolt, S. Hoeppener, U. S. Schubert, O. Glatter, F. Wiesbrock
Crosslinkable/functionalizable poly(2-oxazoline)based micellesExternal link
Eur. Polym. J. 2019, 121, 109305.

I. Tabujew, M. Heidari, C. Freidel, M. Helm, L. Tebbe, U. Wolfrum, K. Nagel-Wolfrum, K. Koynov, P. Biehl, F. H. Schacher, R. Potestio, K. Peneva
Tackling the limitations of copolymeric small interfering RNA delivery agents by a combined experimental–computational approachExternal link
Biomacromolecules 2019, 20, 4389-4406.

I. Tabujew, M. Willig, N. Leber, C. Freidel, I. Negwer, K. Koynov, M. Helm, K. Landfester, R. Zentel, K. Peneva, V. Mailänder
Overcoming the barrier of CD8+ T cells: Two types of nano-sized carriers for siRNA transportExternal link
Acta Biomaterialia 2019, 100, 338-351.

R. Yañez-Macías, A. Muñoz-Bonilla, M. A. De Jesús-Tellez, H. Maldonado-Textle, C. Guerrero-Sánchez, U. S. Schubert, R. Guerrero-Santos
Combinations of antimicrobial polymers with nanomaterials and bioactives to improve biocidal therapiesExternal link
Polymers 2019, 11, 1789.

M. Yarbakht, P. Pradhan, N. Köse-Vogel, H. Bae, S. Stengel, T. Meyer, M. Schmitt, A. Stallmach, J. Popp, T. W. Bocklitz, T. Bruns
Nonlinear multimodal imaging characteristics of early septic liver injury in a mouse model of peritonitisExternal link
Anal. Chem. 2019, 91, 11116-11121.
2018
F. L. Kriegel, R. Köhler, J. Bayat-Sarmadi, S. Bayerl, A. E. Hauser, R. Niesner, A. Luch, Z. Cseresnyes
Morphology-based distinction between healthy and pathological cells utilizing fourier transforms and self-organizing mapsExternal link
JoVE 2018, e58543.

N. Teich, T. Bruns, A. Stallmach
Letter: predicting azathioprine-associated pancreatitis in IBD—phenotype or genotype?External link
Aliment. Pharmacol. Ther. 2018, 47, 1042-1043.

C. Englert, J. C. Brendel, T. C. Majdanski, T. Yildirim, S. Schubert, M. Gottschaldt, N. Windhab, U. S. Schubert,
"Pharmapolymers in the 21st Century: Synthetic Polymers in Drug Delivery ApplicationsExternal link",
Prog. Polym. Sci. 2018, DOI: 10.1016/j.progpolymsci.2018.1007.1005.

P. Dasari, I. A. Shopova, M. Stroe, D. Wartenberg, H. Martin-Dahse, N. Beyersdorf, P. Hortschansky, S. Dietrich, Z. Cseresnyés, M. T. Figge, M. Westermann, C. Skerka, A. A. Brakhage, P. F. Zipfel,
"Aspf2 from Aspergillus fumigatus recruits human immune regulators for immune evasion and cell damageExternal link",
Front. Immunol. 2018, 9, 1635.

L. Vieider, E. Romp, V. Temml, J. Fischer, C. Kretzer, M. Schoenthaler, A. Taha, V. Hernández-Olmos, S. Sturm, D. Schuster, O. Werz, U. Garscha, B. Matuszczak,
"Synthesis, biological evaluation and structureactivity relationships of diflapolin analogues as dual sEH/FLAP inhibitorsExternal link",
ACS Med. Chem. Lett. 2018, DOI: 10.1021/acsmedchemlett.8b00415.

M. Brunzel, T. Majdanski, J. Vitz, I. Nischang, U. Schubert,
"Fast screening of diol impurities in methoxy poly(ethylene glycol)s (mPEG)s by liquid chromatography on monolithic silica rodsExternal link",
Polymers 2018, 10, 1395.

T. C. Majdanski, J. Vitz, A. Meier, M. Brunzel, S. Schubert, I. Nischang, U. S. Schubert,
"Green ethers as solvent alternatives for anionic ring-opening polymerizations of ethylene oxide (EO): In-situ kinetic and advanced characterization studiesExternal link",
Polymer 2018, 159, 86-94.

M. Dirauf, D. Bandelli, C. Weber, H. Görls, M. Gottschaldt, U. S. Schubert,
"TBD-catalyzed ring-opening polymerization of alkyl-substituted morpholine-2,5-dione derivativesExternal link",
Macromol. Rapid Commun. 2018, 39, 1800433.

H. Pein, A. Ville, S. Pace, V. Temml, U. Garscha, M. Raasch, K. Alsabil, G. Viault, C.-P. Dinh, D. Guilet, F. Troisi, K. Neukirch, S. König, R. Bilancia, B. Waltenberger, H. Stuppner, M. Wallert, S. Lorkowski, C. Weinigel, S. Rummler, M. Birringer, F. Roviezzo, L. Sautebin, J.-J. Helesbeux, D. Séraphin, A. Mosig, D. Schuster, A. Rossi, P. Richomme, O. Werz, A. Koeberle,
"Endogenous metabolites of vitamin E limit inflammation by targeting 5 lipoxygenaseExternal link",
Nat. Commun. 2018, 9, 3834.

H. Würfel, M. Kayser, T. Heinze,
"Efficient and catalyst-free synthesis of cellulose acetoacetatesExternal link",
Cellulose 2018, 25, 4919-4928.

K. Ganske, T. Heinze,
"Evaluation of the synthesis of soluble aromatic cellulose carbonates of low degree of substitutionExternal link",
Macromol. Chem. Phys. 2018, 219, 1800152.

T. Bus, A. Traeger, U. S. Schubert,
"The great escape: how cationic polyplexes overcome the endosomal barrierExternal link",
J. Mater. Chem. B 2018, 6, 6904-6918.

M. Bauer, L. Tauhardt, H. M. L. Lambermont-Thijs, K. Kempe, R. Hoogenboom, U. S. Schubert, D. Fischer,
"Rethinking the impact of the protonable amine density on cationic polymers for gene delivery: A comparative study of partially hydrolyzed poly(2-ethyl-2-oxazoline)s and linear poly(ethylene imine)sExternal link",
Eur. J. Pharm. Biopharm. 2018, 133, 112-121.

J. F. Herrmann, C. Höppener,
"Dumbbell gold nanoparticle dimer antennas with advanced optical propertiesExternal link",
Beilst. J. Nanotechnol. 2018, 9, 2188-2197.

R. Meyer, X. Yao, V. Deckert,
"Latest instrumental developments and bioanalytical applications in tip-enhanced Raman spectroscopyExternal link",
Trends Anal. Chem. 2018, 102, 250-258.

D. Bandelli, C. Helbing, C. Weber, M. Seifert, I. Muljajew, K. D. Jandt, U. S. Schubert,
"Maintaining the hydrophilichydrophobic balance of polyesters with adjustable crystallinity for tailor-made nanoparticlesExternal link",
Macromolecules 2018, 51, 5567-5576.

S.-Y. Cheung, M. Werner, L. Esposito, F. Troisi, V. Cantone, S. Liening, S. König, J. Gerstmeier, A. Koeberle, R. Bilancia, R. Rizza, A. Rossi, F. Roviezzo, V. Temml, D. Schuster, H. Stuppner, M. Schubert-Zsilavecz, O. Werz, T. Hanke, S. Pace,
"Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammationExternal link",
Eur. J. Med. Chem. 2018, 156, 815-830.

A. Koeberle, A. Henkel, M. Verhoff, L. Tausch, S. König, D. Fischer, N. Kather, S. Seitz, M. Paul, J. Jauch, O. Werz,
"Triterpene acids from Frankincense and semi-synthetic derivatives that inhibit 5-lipoxygenase and cathepsin GExternal link",
Molecules 2018, 23, 506.

A.-K. Trützschler, T. Bus, M. Sahn, A. Traeger, C. Weber, U. S. Schubert,
"The power of shielding: Low toxicity and high transfection performance of cationic graft copolymers containing poly(2-oxazoline) side chainsExternal link",
Biomacromolecules 2018, 19, 2759-2771.

M. Grube, M. N. Leiske, U. S. Schubert, I. Nischang,
"POx as an alternative to PEG? A hydrodynamic and light scattering studyExternal link",
Macromolecules 2018, 51, 1905-1916.

Z. T. Gür, B. Çalışkan, U. Garscha, A. Olgaç, U. S. Schubert, J. Gerstmeier, O. Werz, E. Banoglu,
"Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7External link",
Eur. J. Med. Chem. 2018, 150, 876-899.

D. Hertz, M. N. Leiske, T. Wloka, A. Traeger, M. Hartlieb, M. M. Kessels, S. Schubert, B. Qualmann, U. S. Schubert,
"Comparison of random and gradient amino functionalized poly(2-oxazoline)s: Can the transfection efficiency be tuned by the macromolecular structure?External link",
J. Polym. Sci., Part A: Polym. Chem. 2018, DOI: 10.1002/pola.29000.

M. N. Leiske, F. H. Sobotta, F. Richter, S. Hoeppener, J. C. Brendel, A. Traeger, U. S. Schubert,
"How to tune the gene delivery and biocompatibility of poly(2-(4-aminobutyl)-2-oxazoline) by self- and coassemblyExternal link",
Biomacromolecules 2018, 19, 748-760.

I. Muljajew, C. Weber, I. Nischang, U. Schubert,
"PMMA-g-OEtOx graft copolymers: Influence of grafting degree and side chain length on the conformation in aqueous solutionExternal link",
Materials 2018, 11, 528.

M. Reifarth, S. Hoeppener, U. S. Schubert,
"Uptake and intracellular fate of engineered nanoparticles in mammalian cells: Capabilities and limitations of transmission electron microscopypolymerbased nanoparticlesExternal link",
Adv. Mater. 2018, 30, 1703704.

W. S. Zhang, X. Q. Yu, Y. Li, Z. Q. Su, K. D. Jandt, G. Wei,
"Protein-mimetic peptide nanofibers: Motif design, self-assembly synthesis, and sequence-specific biomedical applicationsExternal link",
Prog. Polym. Sci. 2018, 80, 94-124.

M. Reifarth, U. S. Schubert, S. Hoeppener,
"Considerations for the uptake characteristic of inorgainc nanoparticles into mammalian cells - Insights gained by TEM investigationsExternal link",
Adv. Biosys. 2018, DOI: 10.1002/adbi.201700254.

M. Sahn, L. M. Stafast, M. Dirauf, D. Bandelli, C. Weber, U. S. Schubert,
"LCST behavior of poly(2-ethyl-2-oxazoline) containing diblock and triblock copolymersExternal link",
Eur. Polym. J. 2018, 100, 57-66.

F. H. Sobotta, F. Hausig, D. O. Harz, S. Hoeppener, U. S. Schubert, J. C. Brendel,
"Oxidation-responsive micelles by a one-pot polymerization-induced self-assembly approachExternal link",
Polym. Chem. 2018, 9, 1593-1602.

P. Wei, S. Götz, S. Schubert, J. C. Brendel, U. S. Schubert,
"Accelerating the acidic degradation of a novel thermoresponsive polymer by host-guest interactionExternal link",
Polym. Chem. 2018, 9, 2634-2642.

A.-K. Trützschler, T. Bus, M. Reifarth, J. C. Brendel, S. Hoeppener, A. Traeger, U. S. Schubert,
"Beyond gene transfection with methacrylate-based polyplexesthe influence of the amino substitution patternExternal link",
Bioconjugate Chem. 2018, 29, 2181-2194.

A. Koeberle, O. Werz,
"Natural products as inhibitors of prostaglandin E2 and pro-inflammatory 5-lipoxygenase-derived lipid mediator biosynthesisExternal link",
Biotechnol. Adv. 2018, 36, 1709-1723.

L. Volkmann, M. Köhler, F. H. Sobotta, M. T. Enke, J. C. Brendel, F. H. Schacher,
"Poly(2-acrylamidoglycolic acid) (PAGA): Controlled polymerization using RAFT and chelation of metal cationsExternal link",
Macromolecules 2018, DOI: 10.1021/acs.macromol.1028b01260.

J. Zhang, B. Farias-Mancilla, M. Destarac, U. S. Schubert, D. J. Keddie, C. Guerrero-Sanchez, S. Harrisson,"Asymmetric copolymers: Synthesis, properties, and applications of gradient and other partially segregated copolymersExternal link",
Macromol. Rapid Commun. 2018, 39, 1800357.

S. Miwa, R. Takahashi, C. Rössel, S. Matsumoto, S. Fujii, J. H. Lee, F. H. Schacher, K. Sakurai
Core–shell–corona micelles from a polyether-based triblock terpolymer: Investigation of the pH-dependent micellar structureExternal link
Langmuir 2018, 34, 7813-7820.

C. Guerrero‐Sanchez, J. Zhang, J. Vitz, U. S. Schubert
High-throughput synthesis of polymersExternal link
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2017
A. T. Press, A. Ramoji, M. vd Lühe, A. C. Rinkenauer, J. Hoff, M. Butans, C. Rössel, C. Pietsch, U. Neugebauer, F. H. Schacher, M. Bauer
Cargocarrier interactions significantly contribute to micellar conformation and biodistributionExternal link
NPG Asia Materials 2017, 9, e444.

M. Pröhl, S. Seupel, P. Sungur, S. Höppener, M. Gottschaldt, J. C. Brendel, U. S. Schubert
The influence of the grafting density of glycopolymers on the lectin binding affinity of block copolymer micellesExternal link
Polymer 2017, 133, 205-212.

I. Perevyazko, A. S. Gubarev, L. Tauhardt, A. Dobrodumov, G. M. Pavlov, U. S. Schubert
Linear poly(ethylene imine)s: true molar masses, solution properties and conformationExternal link
Polym. Chem. 2017, 8, 7169-7179.

R. Heintzmann, T. Huser
Super-resolution structured illumination microscopyExternal link
Chem. Rev. 2017, 117, 13890-13908.