
Publications
A woman in a library
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2022
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Further information will follow soon.
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2021
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- A. M. Ali, M. Egiza, K. Murasawa, H. Sugita, T. Deckert-Gaudig, V. Deckert, T. Yoshitake
Effects of substrate temperature and intermediate layer on adhesion, structural and mechanical properties of coaxial arc plasma deposition grown nanodiamond composite films on Si substrates
Surf. Coat. Technol. 2021, 417, 127185. - T. T. V. Anh, A. Mostafa, Z. G. Rao, S. Pace, S. Schwaiger, C. Kretzer, V. Temml, C. Giesel, P. M. Jordan, R. Bilancia, C. Weinigel, S. Rummler, B. Waltenberger, T. Hung, A. Rossi, H. Stuppner, O. Werz, A. Koeberle
From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution
Acta Pharmaceutica Sinica B 2021, 11, 1629-1647. - M. Brunzel, M. Dirauf, M. Sahn, J. A. Czaplewska, N. Fritz, C. Weber, I. Nischang, U. S. Schubert
On the identification and quantification of proton-initiated species in the synthesis of poly(2-alkyl-2-oxazoline)s by high resolution liquid chromatography
J. Chromatogr. A 2021, 1653, 462364. - H. Büttner, S. P. Niehs, K. Vandelannoote, Z. Cseresnyés, B. Dose, I. Richter, R. Gerst, M. T. Figge, T. P. Stinear, S. J. Pidot, C. Hertweck
Bacterial endosymbionts protect beneficial soil fungus from nematode attack
PNAS 2021, 118, e2110669118. - C. Chen, F. Richter, J. L. Zhang, C. Guerrero-Sanchez, A. Traeger, U. S. Schubert, A. C. Feng, S. H. Thang
Synthesis of functional miktoarm star polymers in an automated parallel synthesizer
Eur. Polym. J. 2021, 160, 110777. - Y. L. Chen, K. L. Rudolph
Granulocyte colony-stimulating factor acts on lymphoid-biased, short-term hematopoietic stem cells
Haematologica 2021, 106, 1516-1518. - C. Cokca, F. J. Hack, D. Costabel, K. Herwig, J. Hulsmann, P. Then, R. Heintzmann, D. Fischer, K. Peneva
PEGylation of guanidinium and indole bearing poly(methacrylamide)s - Biocompatible terpolymers for pDNA delivery
Macromol. Biosci. 2021, 21, 2100146. - E. Y. Darussalam, O. Peterfi, T. Deckert-Gaudig, L. Roussille, V. Deckert
pH-dependent disintegration of insulin amyloid fibrils monitored with atomic force microscopy and surface-enhanced Raman spectroscopy
Spectrochim. Acta A Mol. Biomol. Spect. 2021, 256, 119672. - M. A. De Jesus-Tellez, S. De la Rosa-Garcia, I. Medrano-Galindo, I. Rosales-Penafiel, S. Gomez-Cornelio, C. Guerrero-Sanchez, U. S. Schubert, P. Quintana-Owen
Antifungal properties of poly 2-(dimethylamino)ethyl methacrylate (PDMAEMA) and quaternized derivatives
React. Funct. Polym. 2021, 163, 104887. - S. Deb, D. A. Felix, P. Koch, M. K. Deb, K. Szafranski, K. Buder, M. Sannai, M. Groth, J. Kirkpatrick, S. Pietsch, A. Gollowitzer, A. Gross, P. Riemenschneider, A. Koeberle, C. Gonzalez-Estevez, K. L. Rudolph
Tnfaip2/exoc3-driven lipid metabolism is essential for stem cell differentiation and organ homeostasis
EMBO Rep. 2021, 22, e49328. - S. Deinhardt-Emmer, S. Bottcher, C. Haring, L. Giebeler, A. Henke, R. Zell, J. Jungwirth, P. M. Jordan, O. Werz, F. Hornung, C. Brandt, M. Marquet, A. S. Mosig, M. W. Pletz, M. Schacke, J. Rodel, R. Heller, S. Nietzsche, B. Loffler, C. Ehrhardt
SARS-CoV-2 causes severe epithelial inflammation and barrier dysfunction
J. Virol. 2021, 95, e00110-21. - M. Dirauf, N. Fritz, M. Gottschaldt, C. Weber, U. S. Schubert
Poly(2-ethyl-2-oxazoline) featuring a central amino moiety
Macromol. Rapid Commun. 2021, 42, 2100132. - D. Fischer, N. Dusek, K. Hotzel, T. Heinze
The role of formamidine groups in dextran based nonviral vectors for gene delivery on their physicochemical and biological characteristics
Macromol. Biosci. 2021, 21, 2000220. - L. Friedrich, G. Cingolani, Y. H. Ko, M. Iaselli, M. Miciaccia, M. G. Perrone, K. Neukirch, V. Bobinger, D. Merk, R. K. Hofstetter, O. Werz, A. Koeberle, A. Scilimati, G. Schneider
Learning from nature: From a marine natural product to synthetic cyclooxygenase-1 inhibitors by automated de novo design
Adv. Sci. 2021, 8, 2100832. - A. N. Garcia-Sanchez, R. Yanez-Macias, J. L. Hernandez-Flores, A. Alvarez-Morales, J. H. Valenzuela-Soto, C. Guerrero-Sanchez, R. Guerrero-Santos
Exogenous application of polycationic nanobactericide on tomato plants reduces the candidatus liberibacter solanacearum infection
Plants 2021, 10, 2096. - N. C. Gilbert, M. E. Newcomer, O. Werz
Untangling the web of 5-lipoxygenase-derived products from a molecular and structural perspective: The battle between pro- and anti-inflammatory lipid mediators
Biochem. Pharmacol. 2021, 193, 114759. - N. E. Göppert, M. Dirauf, C. Weber, U. S. Schubert
Block copolymers comprising degradable poly(2-ethyl-2-oxazoline) analogues via copper-free click chemistry
Polym. Chem. 2021, 12, 5426–5437. - C. Grune, C. Kretzer, S. Zergiebel, S. Kattner, J. Thamm, S. Hoeppener, O. Werz, D. Fischer
Encapsulation of the anti-inflammatory dual FLAP/sEH inhibitor diflapolin improves the efficiency in human whole blood
J. Pharm. Sci. 2021, DOI: 10.1016/j.xphs.2021.10.030 - C. Grune, C. Zens, A. Czapka, K. Scheuer, J. Thamm, S. Hoeppener, K. D. Jandt, O. Werz, U. Neugebauer, D. Fischer
Sustainable preparation of anti-inflammatory atorvastatin PLGA nanoparticles
Int. J. Pharm. 2021, 599, 120404. - F. V. Gruschwitz, T. Klein, M. T. Kuchenbrod, N. Moriyama, S. Fujii, I. Nischang, S. Hoeppener, K. Sakurai, U. S. Schubert, J. C. Brendel
Kinetically controlling the length of self-assembled polymer nanofibers formed by intermolecular hydrogen bonds
ACS Macro Lett. 2021, 10, 837-843. - T. Gürses, A. Olğaç, U. Garscha, T. Gür Maz, N. B. Bal, O. Uludağ, B. Çalışkan, U. S. Schubert, O. Werz, E. Banoglu
Simple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacy
Bioorg. Chem. 2021, 112, 104861. - O. Gutierrez-Gutierrez, D. A. Felix, A. Salvetti, E. M. Amro, A. Thems, S. Pietsch, A. Koeberle, K. L. Rudolph, C. Gonzalez-Estevez
Regeneration in starved planarians depends on TRiC/CCT subunits modulating the unfolded protein response
EMBO Rep. 2021, 22, e52905. - S. Hanio, J. Schlauersbach, B. Lenz, F. Spiegel, R. A. Böckmann, R. Schweins, I. Nischang, U. S. Schubert, S. Endres, A.-C. Pöppler, F. P. Brandl, T. M. Smit, K. Kolter, L. Meinel
Drug-induced dynamics of bile colloids
Langmuir 2021, 37, 2543-2551. - M. I. A. Hassan, M. Keller, M. Hillger, U. Binder, S. Reuter, K. Herold, A. Telagathoti, H.-M. Dahse, S. Wicht, N. Trinks, S. Nietzsche, T. Deckert-Gaudig, V. Deckert, R. Mrowka, U. Terpitz, H. Peter Saluz, K. Voigt
The impact of episporic modification of Lichtheimia corymbifera on virulence and interaction with phagocytes
Comput. Struct. Biotechnol. J. 2021, 19, 880-896. - F. Hausig, F. H. Sobotta, F. Richter, D. O. Harz, A. Traeger, J. C. Brendel
Correlation between protonation of tailor-made polypiperazines and endosomal escape for cytosolic protein delivery
ACS Appl. Mater. Interfaces 2021, 13, 35233-35247. - R. Heintzmann
Answers to fundamental questions in superresolution microscopy
Philos. Trans. A Math. Phys. Eng. Sci. 2021, 379. - P. M. Jordan, N. Andreas, M. Groth, P. Wegner, F. Weber, U. Jager, C. Kuchler, O. Werz, E. Serfling, T. Kamradt, A. Dudeck, S. Drube
ATP/IL-33-triggered hyperactivation of mast cells results in an amplified production of pro-inflammatory cytokines and eicosanoids
Immunology 2021, 164, 541-554. - P. M. Jordan, O. Werz
Specialized pro-resolving mediators: Biosynthesis and biological role in bacterial infections
FEBS J. 2021, DOI: 10.1111/febs.16266 - T. Kammann, J. Hoff, I. Yildirim, B. Shkodra, T. Müller, C. Weber, M. H. Gräler, U. A. Maus, J. C. Paton, M. Singer, A. Traeger, U. S. Schubert, M. Bauer, A. T. Press
Intracellularly released cholesterol from polymer-based delivery systems alters cellular responses to pneumolysin and promotes cell survival
Metabolites 2021, 11, 821. - J. Kimmig, T. Schuett, A. Vollrath, S. Zechel, U. S. Schubert
Prediction of nanoparticle sizes for arbitrary methacrylates using artificial neuronal networks
Adv. Sci. 2021, 8, 2102429. - J. Kimmig, S. Zechel, U. S. Schubert
Digital transformation in materials science: A paradigm change in material's development
Adv. Mater. 2021, 33, 2004940. - T. Klein, F. V. Gruschwitz, M. T. Kuchenbrod, I. Nischang, S. Hoeppener, J. C. Brendel
Adjusting the length of supramolecular polymer bottlebrushes by top-down approaches
Beilst. J. Org. Chem. 2021, 17, 2621-2628. - T. Klein, H. F. Ulrich, F. V. Gruschwitz, M. T. Kuchenbrod, R. Takahashi, S. Hoeppener, I. Nischang, K. Sakurai, J. C. Brendel
Overcoming the necessity of a lateral aggregation in the formation of supramolecular polymer bottlebrushes in water
Macromol. Rapid Commun. 2021, 42, 2000585. - P. Klemm, M. Behnke, J. I. Solomun, C. Bonduelle, S. Lecommandoux, A. Traeger, S. Schubert
Self-assembled PEGylated amphiphilic polypeptides for gene transfection
J. Mater. Chem. B 2021, 9, 8149-8356. - S. Kluge, M. Schubert, L. Bormel, S. Lorkowski
The vitamin E long-chain metabolite alpha-13 '-COOH affects macrophage foam cell formation via modulation of the lipoprotein lipase system
Biochim. Biophys. Acta - Mol. Cell Biol. Lipids 2021, 1866, 158875. - M. Kohler, P. Rinke, K. Fiederling, H. Gorls, N. Ueberschaar, F. H. Schacher, R. Kretschmer
Catalytic activity of various beta-diketiminate zinc complexes toward the ring-opening polymerization of caprolactone and derivatives
Macromol. Chem. Phys. 2021, 222, 2100187. - B. Kokot, H. Kokot, P. Umek, K. P. van Midden, S. Pajk, M. Garvas, C. Eggeling, T. Koklic, I. Urbancic, J. Strancar
How to control fluorescent labeling of metal oxide nanoparticles for artefact-free live cell microscopy
Nanotoxicology 2021, 15, 1102-1123. - M. T. Kuchenbrod, U. S. Schubert, R. Heintzmann, S. Hoeppener
Revisiting staining of biological samples for electron microscopy: perspectives for recent research
Mater. Horiz. 2021, 8, 685-699. - M. Kuhne, C. Kretzer, H. Lindemann, M. Godmann, T. Heinze, O. Werz, T. Heinzel
Biocompatible valproic acid-coupled nanoparticles attenuate lipopolysaccharide-induced inflammation
Int. J. Pharm. 2021, 601, 120567. - M. Kuhne, H. Lindemann, C. Grune, D. Schroder, Z. Cseresnyes, M. Godmann, A. Koschella, M. T. Figge, C. Eggeling, D. Fischer, T. Heinze, T. Heinzel
Biocompatible sulfated valproic acid-coupled polysaccharide-based nanocarriers with HDAC inhibitory activity
J. Control. Release 2021, 329, 717-730. - V. D. Lechuga-Islas, M. Trejo-Maldonado, S. Stumpf, R. Guerrero-Santos, L. Elizalde-Herrera, U. S. Schubert, C. Guerrero-Sanchez
Separation of volatile compounds from polymers by physisorption
Eur. Polym. J. 2021, 159, 110748. - K. Leer, G. Cinar, J. I. Solomun, L. Martin, I. Nischang, A. Traeger
Core-crosslinked, temperature- and pH-responsive micelles: design, physicochemical characterization, and gene delivery application
Nanoscale 2021, 13, 19412-19429. - B. Loffler, L. Tuchscherr
Staphylococcus aureus toxins: Promoter or handicap during infection?
Toxins 2021, 13, 287. - I. Muljajew, M. Chi, A. Vollrath, C. Weber, B. Beringer-Siemers, S. Stumpf, S. Hoeppener, M. Sierka, U. S. Schubert
A combined experimental and in silico approach to determine the compatibility of poly(ester amide)s and indomethacin in polymer nanoparticles
Eur. Polym. J. 2021, 156, 110606. - I. Muljajew, S. Huschke, A. Ramoji, Z. Cseresnyés, S. Hoeppener, I. Nischang, W. Foo, J. Popp, M. T. Figge, C. Weber, M. Bauer, U. S. Schubert, A. T. Press
Stealth effect of short polyoxazolines in graft copolymers: Minor changes of backbone end group determine liver cell-type specificity
ACS Nano 2021, 15, 12298–12313 - K. Neukirch, K. Alsabil, C. P. Dinh, R. Bilancia, M. Raasch, A. Ville, I. Cerqua, G. Viault, D. Breard, S. Pace, V. Temml, E. Brunner, P. M. Jordan, M. C. Marques, K. Loeser, A. Gollowitzer, S. Permann, J. Gerstmeier, S. Lorkowski, H. Stuppner, U. Garscha, T. Rodrigues, G. J. L. Bernardes, D. Schuster, D. Seraphin, P. Richomme, A. Rossi, A. S. Mosig, F. Roviezzo, O. Werz, J. J. Helesbeux, A. Koeberle
Exploration of long-chain vitamin E metabolites for the discovery of a highly potent, orally effective, and metabolically stable 5-LOX Inhibitor that limits inflammation
J. Med. Chem. 2021, 64, 11496-11526. - M. F. Osuchowski, M. S. Winkler, T. Skirecki, S. Cajander, M. Shankar-Hari, G. Lachmann, G. Monneret, F. Venet, M. Bauer, F. M. Brunkhorst, S. Weis, A. Garcia-Salido, M. Kox, J.-M. Cavaillon, F. Uhle, M. A. Weigand, S. B. Flohé, W. J. Wiersinga, R. Almansa, A. de la Fuente, I. Martin-Loeches, C. Meisel, T. Spinetti, J. C. Schefold, C. Cilloniz, A. Torres, E. J. Giamarellos-Bourboulis, R. Ferrer, M. Girardis, A. Cossarizza, M. G. Netea, T. van der Poll, J. F. Bermejo-Martín, I. Rubio
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
The Lancet Respiratory Medicine 2021, 9, 622-642. - S. Pace, K. Zhang, P. M. Jordan, R. Bilancia, W. Wang, F. Börner, R. K. Hofstetter, M. Potenza, C. Kretzer, J. Gerstmeier, D. Fischer, S. Lorkowski, N. C. Gilbert, M. E. Newcomer, A. Rossi, X. Chen, O. Werz
Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators
Pharmacol. Res. 2021, 167, 105556. - H. Penkert, A. Bertrand, V. Tiwari, S. Breimann, S. A. Muller, P. M. Jordan, M. J. Gerl, C. Klose, L. Cantuti-Castelvetri, M. Bosch-Queralt, I. Levental, S. F. Lichtenthaler, O. Werz, M. Simons
Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recovery
Cell Reports 2021, 37, 109898. - M. Potenza, M. Sciarretta, M. G. Chini, A. Saviano, F. Maione, M. V. D'Auria, S. De Marino, A. Giordano, R. K. Hofstetter, C. Festa, O. Werz, G. Bifulco
Structure-based screening for the discovery of 1,2,4-oxadiazoles as promising hits for the development of new anti-inflammatory agents interfering with eicosanoid biosynthesis pathways
Eur. J. Med. Chem. 2021, 224, 113693. - A. T. Press, P. Babic, B. Hoffmann, T. Müller, W. Foo, W. Hauswald, J. Benecke, M. Beretta, Z. Cseresnyés, S. Hoeppener, I. Nischang, S. M. Coldewey, M. H. Gräler, R. Bauer, F. Gonnert, N. Gaßler, R. Wetzker, M. T. Figge, U. S. Schubert, M. Bauer
Targeted delivery of a phosphoinositide 3-kinase γ inhibitor to restore organ function in sepsis
EMBO Mol. Med. 2021, 13, e14436. - L. Pusch, R. Brox, K. Scheuer, T. Yokosawa, M. Wu, B. A. Zubiri, E. Spiecker, K. D. Jandt, D. Fischer, H. Hackstein
Distinct endocytosis and immune activation of poly(lactic-co-glycolic) acid nanoparticles prepared by single- and double-emulsion evaporation
Nanomedicine 2021, 16, 2075-2094. - F. Richter, K. Leer, L. Martin, P. Mapfumo, J. I. Solomun, M. T. Kuchenbrod, S. Hoeppener, J. C. Brendel, A. Traeger
The impact of anionic polymers on gene delivery: how composition and assembly help evading the toxicity-efficiency dilemma
J. Nanobiotechnol. 2021, 19, 292. - F. Richter, P. Mapfumo, L. Martin, J. I. Solomun, F. Hausig, J. J. Frietsch, T. Ernst, S. Hoeppener, J. C. Brendel, A. Traeger
Improved gene delivery to K-562 leukemia cells by lipoic acid modified block copolymer micelles
J. Nanobiotechnol. 2021, 19, 70. - T. Ritschel, K. Lehmann, M. Brunzel, J. Vitz, I. Nischang, U. S. Schubert, K. U. Totsche
Well-defined poly(ethylene glycol) polymers as non-conventional reactive tracers of colloidal transport in porous media
J. Colloid Interface Sci. 2021, 584, 592-601. - M. Rodewald, H. Bae, S. Huschke, T. Meyer-Zedler, M. Schmitt, A. T. Press, S. Schubert, M. Bauer, J. Popp
In vivo coherent anti-Stokes Raman scattering microscopy reveals vitamin A distribution in the liver
J. Biophotonics 2021, 14, e202100040. - E. Rujas, D. P. Leaman, S. Insausti, P. Carravilla, M. Garcia-Porras, E. Largo, I. Morillo, R. Sanchez-Eugenia, L. Zhang, H. Cui, I. Iloro, F. Elortza, J. P. Julien, C. Eggeling, M. B. Zwick, J. M. M. Caaveiro, J. L. Nieva
Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile
Iscience 2021, 24, 102987. - P. Schädel, F. Troisi, A. Czapka, N. Gebert, S. Pace, A. Ori, O. Werz
Aging drives organ-specific alterations of the inflammatory microenvironment guided by immunomodulatory mediators in mice
The FASEB Journal 2021, 35, e21558. - F. Schneider, T. Sych, C. Eggeling, E. Sezgin
Influence of nanobody binding on fluorescence emission, mobility, and organization of GFP-tagged proteins
Iscience 2021, 24, 101891. - M. Sittig, J. C. Tom, J. K. Elter, F. H. Schacher, B. Dietzek
Quinoline photobasicity: Investigation within water-soluble light-responsive copolymers
Chem. Eur. J. 2021, 27, 1072-1079. - F. H. Sobotta, M. T. Kuchenbrod, C. Grune, D. Fischer, S. Hoeppener, J. C. Brendel
Elucidating preparation-structure relationships for the morphology evolution during the RAFT dispersion polymerization of N-acryloyl thiomorpholine
Polym. Chem. 2021, 12, 1668-1680. - F. H. Sobotta, M. T. Kuchenbrod, F. V. Gruschwitz, G. Festag, P. Bellstedt, S. Hoeppener, J. C. Brendel
Tuneable time delay in the burst release from oxidation-sensitive polymersomes made by PISA
Angew. Chem. Int. Ed. 2021, 60, 24716-24723. - O. Sommerfeld, A. Medyukhina, S. Neugebauer, M. Ghait, S. Ulferts, A. Lupp, R. König, R. Wetzker, S. Schulz, M. T. Figge, M. Bauer, A. T. Press
Targeting complement C5a receptor 1 for the treatment of immunosuppression in sepsis
Mol. Ther. 2021, 29, 338-346. - F. A. Stanford, N. Matthies, Z. Cseresnyés, M. T. Figge, M. I. A. Hassan, K. Voigt
Expression patterns in reductive iron assimilation and functional consequences during phagocytosis of Lichtheimia corymbifera, an emerging cause of mucormycosis
Journal of Fungi 2021, 7, 272. - B. H. Stumpf, P. Nowakowski, C. Eggeling, A. Maciolek, A. S. Smith
Protein induced lipid demixing in homogeneous membranes
Phys. Rev. Res. 2021, 3, L042013. - A. Tannert, J. G. Lopez, N. Petkov, A. Ivanova, K. Peneva, U. Neugebauer
Lysosome-targeting pH indicator based on peri-fused naphthalene monoimide with superior stability for long term live cell imaging
J. Mater. Chem. B 2021, 9, 112-124. - I. Urbancic, L. Schiffelers, E. Jenkins, W. J. Gong, A. M. Santos, F. Schneider, C. O'Brien-Ball, M. T. Vuong, N. Ashman, E. Sezgin, C. Eggeling
Aggregation and mobility of membrane proteins interplay with local lipid order in the plasma membrane of T cells
FEBS Lett. 2021, 595, 2127-2146. - A. Vollrath, C. Kretzer, B. Beringer-Siemers, B. Shkodra, J. A. Czaplewska, D. Bandelli, S. Stumpf, S. Hoeppener, C. Weber, O. Werz, U. S. Schubert
Effect of crystallinity on the properties of polycaprolactone nanoparticles containing the dual FLAP/mPEGS-1 inhibitor BRP-187
Polymers 2021, 13, 2557. - L. Wang, U. S. Schubert, S. Hoeppener
Surface chemical reactions on self-assembled silane based monolayers
Chem. Soc. Rev. 2021, 50, 6507-6540. - L. Wang, A. A. Womiloju, C. Höppener, U. S. Schubert, S. Hoeppener
On the stability of microwave-fabricated SERS substrates – chemical and morphological considerations
Beilst. J. Nanotechnol. 2021, 12, 541-551. - S. Willems, L. Gellrich, A. Chaikuad, S. Kluge, O. Werz, J. Heering, S. Knapp, S. Lorkowski, M. Schubert-Zsilavecz, D. Merk
Endogenous vitamin E metabolites mediate allosteric PPARγ activation with unprecedented co-regulatory interactions
Cell Chem. Biol. 2021, 28, 1489-1500. - J. L. Zhang, B. Farias-Mancilla, I. Kulai, S. Hoeppener, B. Lonetti, S. Prevost, J. Ulbrich, M. Destarac, O. Colombani, U. S. Schubert, C. Guerrero-Sanchez, S. Harrisson
Effect of hydrophilic monomer distribution on self-assembly of a pH-responsive copolymer: Spheres, worms and vesicles from a single copolymer composition
Angew. Chem. Int. Ed. 2021, 60, 4925-4930. - K. Zhang, S. Pace, P. M. Jordan, L. K. Peltner, A. Weber, D. Fischer, R. K. Hofstetter, X. Chen, O. Werz
Beneficial modulation of lipid mediator biosynthesis in innate immune cells by antirheumatic tripterygium wilfordii glycosides
Biomolecules 2021, 11, 746. - J. Alex, J. Ulbrich, M. Rosales-Guzmán, C. Weber, U. S. Schubert, C. Guerrero-Sanchez
Kinetic investigations on homo- and co-polymerizations of pentafluorophenyl (meth)acrylates
Eur. Polym. J. 2021, 143, 110175. - F. Becker, K. L. Rudolph
Targeting enzyme aging
Science 2021, DOI: 10.1126/science.abf9566. - C. Grune, J. Thamm, O. Werz, D. Fischer
Cyrene™ as an alternative sustainable solvent for the preparation of poly(lactic-co-glycolic acid) nanoparticles
J. Pharm. Sci. 2021, 110, 959-964. - P. Klemm, S. Huschke, M. Rodewald, N. Ehteshamzad, M. Behnke, X. Wang, G. Cinar, I. Nischang, S. Hoeppener, C. Weber, A. Press, C. Höppener, T. Meyer, V. K. Deckert, M. Schmitt, J. Popp, M. Bauer, S. Schubert
Characterization of a library of vitamin A-functionalized polymethacrylate-based nanoparticles for siRNA delivery
Polym. Chem. 2021, DOI: 10.1039/D1030PY01626H. - K. L. Rudolph
Stem cell aging
Mech. Ageing Dev. 2021, 193, 111394. - J. I. Solomun, G. Cinar, P. Mapfumo, F. Richter, E. Moek, F. Hausig, L. Martin, S. Hoeppener, I. Nischang, A. Traeger
Solely aqueous formulation of hydrophobic cationic polymers for efficient gene delivery
Int. J. Pharm. 2021, 593, 120080. - C. St Thomas, L. E. Elizalde, E. J. Regalado, M. A. De Jesús-Téllez, G. Festag, U. S. Schubert, C. Guerrero-Sánchez
Understanding the influence of chemical structure and length of hydrophobic blocks on the rheological properties of associative copolymers
Eur. Polym. J. 2021, 143, 110190.
- A. M. Ali, M. Egiza, K. Murasawa, H. Sugita, T. Deckert-Gaudig, V. Deckert, T. Yoshitake
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2020
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- M. Behnke, A. Vollrath, L. Klepsch, B. Beringer-Siemers, S. Stumpf, J. A. A. Czaplewska, S. Hoeppener, O. Werz, U. S. Schubert
Optimized encapsulation of the FLAP/PGES-1 Inhibitor BRP-187 in PVA-stabilized PLGA nanoparticles using microfluidics
Polymers 2020, 12, 2751. - S. Deb, D. A. Felix, P. Koch, M. K. Deb, K. Szafranski, K. Buder, M. Sannai, M. Groth, J. Kirkpatrick, S. Pietsch, A. Gollowitzer, A. Groß, P. Riemenschneider, A. Koeberle, C. Gonzalez-Estevez, K. L. Rudolph
Tnfaip2/Exoc3-driven lipid metabolism is essential for stem cell differentiation and organ homeostasis
EMBO Rep. 2020, DOI: 10.15252/embr.201949328. - B. Diederich, R. Lachmann, S. Carlstedt, B. Marsikova, H. Wang, X. Uwurukundo, A. Mosig, R. Heintzmann
A versatile and customizable low-cost 3D-printed open standard for microscopic imaging
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Tunable nanogels by host–guest interaction with carboxylate pillar[5]arene for controlled encapsulation and release of doxorubicin
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Microwave-assisted synthesis of core–shell nanoparticles - Insights into the growth of different geometries
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The cortical actin network regulates avidity-dependent binding of hyaluronan by the Lymphatic Vessel Endothelial receptor LYVE-1
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Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity
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Creating supported plasma membrane bilayers using acoustic pressure
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Tuning of endosomal escape and gene expression by functional groups, molecular weight and transfection medium: a structure–activity relationship study
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Block copolymers composed of PEtOx and polyesteramides based on glycolic acid, L-valine, and L-isoleucine
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Targeting mPGES-1 by a combinatorial approach: Identification of the aminobenzothiazole scaffold to suppress PGE2 levels
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Fluorescence microscopy of the HIV-1 envelope
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Polysaccharide nanoparticles bearing HDAC inhibitor as nontoxic nanocarrier for drug delivery
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Revisiting very disperse macromolecule populations in hydrodynamic and light scattering studies of sodium carboxymethyl celluloses
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A polyesteramide library from dicarboxylic acids and 2,2′-bis(2-oxazoline): synthesis, characterization, nanoparticle formulation and molecular dynamics simulations
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Near- and far-field Raman spectroscopic studies of nanodiamond composite films deposited by coaxial arc plasma
Appl. Phys. Lett. 2020, 116, 041601. - C. Chen, F. Richter, C. Guerrero-Sanchez, A. Traeger, U. S. Schubert, A. Feng, S. H. Thang
Cell-penetrating, peptide-based RAFT agent for constructing penetration enhancers
ACS Macro Letters 2020, 9, 260-265. - C. Cokca, L. Zartner, I. Tabujew, D. Fischer, K. Peneva
Incorporation of indole significantly improves the transfection efficiency of guanidinium-containing poly(methacrylamide)s
Macromol. Rapid Commun. 2020, 41, 2070012. - J. A. Czaplewska, G. Gangapurwala, A. Vollrath, M. Pröhl, T. Majdanski, D. Pretzel, S. Hoeppener, U. S. Schubert, M. Gottschaldt
Synthesis of a fructose decorated PAGE-b-PEG-b-PLGA polymer with subsequent formulation of nanoparticles
Colloids Surf. A Physicochem. Eng. Asp. 2020, 124701. - S. Deinhardt-Emmer, K. Rennert, E. Schicke, Z. Cseresnyés, M. Windolph, S. Nietzsche, R. Heller, F. Siwczak, K. F. Haupt, S. Carlstedt, M. Schacke, M. T. Figge, C. Ehrhardt, B. Löffler, A. S. Mosig
Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model
Biofabrication 2020, 12, 025012. - A. Erlebach, I. Muljajew, M. Chi, C. Bückmann, C. Weber, U. S. Schubert, M. Sierka
Predicting solubility of small molecules in macromolecular compounds for nanomedicine application from atomistic simulations
Adv. Theory Simul. 2020, DOI: 10.1002/adts.202000001. - E. Gardey, F. H. Sobotta, S. Hoeppener, T. Bruns, A. Stallmach, J. C. Brendel
Influence of core cross-linking and shell composition of polymeric micelles on immune response and their interaction with human monocytes
Biomacromolecules 2020, DOI: 10.1021/acs.biomac.9b01656. - M. Gericke, P. Schulze, T. Heinze
Nanoparticles based on hydrophobic polysaccharide derivatives—formation principles, characterization techniques, and biomedical applications
Macromol. Biosci. 2020, 1900415. - M. Grube, G. Cinar, U. S. Schubert, I. Nischang
Incentives of using the hydrodynamic invariant and sedimentation parameter for the study of naturally- and synthetically-based macromolecules in solution
Polymers 2020, 12, 277. - K. Hiesinger, A. Schott, J. S. Kramer, R. Blöcher, F. Witt, S. K. Wittmann, D. Steinhilber, D. Pogoryelov, J. Gerstmeier, O. Werz, E. Proschak
Design of dual inhibitors of soluble epoxide hydrolase and LTA4 hydrolase
ACS Med. Chem. Lett. 2020, 11, 298-302. - C. Höppener, F. H. Schacher, V. Deckert
Multimodal characterization of resin embedded and sliced polymer nanoparticles by means of tip-enhanced raman spectroscopy and force–distance curve based atomic force microscopy
Small 2020, 1907418. - J. Hübner, T. Deckert-Gaudig, J. Glorian, V. K. Deckert, D. Spitzer
Surface characterization of nanoscale co-crystals enabled through tip enhanced raman spectroscopy
Nanoscale 2020, DOI: 10.1039/D1030NR00397B. - S. M. A. S. Keshk, A. A. El-Zahhar, Q. A. Alsulami, M. Jaremko, S. Bondock, T. Heinze
Synthesis, characterization and ampyrone drug release behavior of magnetite nanoparticle/2,3-dialdehyde cellulose-6-phosphate composite
Cellulose 2020, 27, 1603-1618. - A. Koschella, C.-Y. Chien, T. Iwata, M. S. Thonhofer, T. M. Wrodnigg, T. Heinze
All sugar based cellulose derivatives synthesized by azide–alkyne click chemistry
Macromol. Chem. Phys. 2020, 221, 1900343. - G. Lauro, S. Terracciano, V. Cantone, D. Ruggiero, K. Fischer, S. Pace, O. Werz, I. Bruno, G. Bifulco
A combinatorial virtual screening approach driving the synthesis of 2,4-thiazolidinedione-based molecules as new dual mPGES-1/5-LO inhibitors
ChemMedChem 2020, 15, 481-489. - V. D. Lechuga-Islas, G. Festag, M. Rosales-Guzmán, O. E. Vega-Becerra, R. Guerrero-Santos, U. S. Schubert, C. Guerrero-Sánchez
Quasi-block copolymer design of quaternized derivatives of poly(2-(dimethylamino)ethyl methacrylate): Investigations on thermo-induced self-assembly
Eur. Polym. J. 2020, 124, 109457. - E. Matuszyk, E. Sierka, M. Rodewald, H. Bae, T. Meyer, E. Kus, S. Chlopicki, M. Schmitt, J. Popp, M. Baranska
Differential response of liver sinusoidal endothelial cells and hepatocytes to oleic and palmitic acid revealed by Raman and CARS imaging
Biochim. Biophys. Acta Mol. Basis Disease 2020, 1866, 165763. - J. B. Max, P. J. Mons, J. C. Tom, F. H. Schacher
Double hydrophilic poly(ethylene oxide)-block-poly(dehydroalanine) block copolymers: Comparison of two different synthetic routes
Macromol. Chem. Phys. 2020, 221, 1900383. - A. Olgac, A. Carotti, C. Kretzer, S. Zergiebel, A. Seeling, U. Garscha, O. Werz, A. Macchiarulo, E. Banoglu
Discovery of novel 5-lipoxygenase-activating protein (FLAP) inhibitors by exploiting a multistep virtual screening protocol
J. Chem. Inf. Model. 2020, 60, 1737-1748. - Z. Rao, P. M. Jordan, Y. Wang, D. Menche, S. Pace, J. Gerstmeier, O. Werz
Differential role of vacuolar (H+)-ATPase in the expression and activity of cyclooxygenase-2 in human monocytes
Biochem. Pharmacol. 2020, 175, 113858. - V. V. Shumyantseva, T. V. Bulko, A. V. Kuzikov, R. A. Masamrekh, A. Y. Konyakhina, I. Romanenko, J. B. Max, M. Köhler, A. A. Gilep, S. A. Usanov, D. V. Pergushov, F. H. Schacher, L. V. Sigolaeva
All-electrochemical nanocomposite two-electrode setup for quantification of drugs and study of their electrocatalytical conversion by cytochromes P450
Electrochimica Acta 2020, 336, 135579. - P. Singh, T. Deckert-Gaudig, Z. Zhang, V. Deckert
Plasmon induced deprotonation of 2-mercaptopyridine
Analyst 2020, 145, 2106-2110. - M. Sittig, B. Schmidt, H. Görls, T. Bocklitz, M. Wächtler, S. Zechel, M. D. Hager, B. Dietzek
Fluorescence upconversion by triplet-triplet annihilation in all-organic poly(methacrylate)-terpolymers
Phys. Chem. Chem. Phys. 2020, 22, 4072-4079. - R. Takahashi, S. Miwa, F. H. Sobotta, J. H. Lee, S. Fujii, N. Ohta, J. C. Brendel, K. Sakurai
Unraveling the kinetics of the structural development during polymerization-induced self-assembly: decoupling the polymerization and the micelle structure
Polym. Chem. 2020, 11, 1514-1524. - A. Traeger, S. Voelker, B. Shkodra-Pula, C. Kretzer, S. Schubert, M. Gottschaldt, U. S. Schubert, O. Werz
Improved bioactivity of the natural product 5-lipoxygenase inhibitor hyperforin by encapsulation into polymeric nanoparticles
Mol. Pharm. 2020, 17, 810-816. - P. Wei, J. A. Czaplewska, L. Wang, S. Schubert, J. C. Brendel, U. S. Schubert
Straightforward access to glycosylated, acid sensitive nanogels by host–guest interactions with sugar-modified pillar[5]arenes
ACS Macro Letters 2020, 9, 540-545. - P. Wei, F. H. Sobotta, C. Kellner, D. Bandelli, S. Hoeppener, S. Schubert, J. C. Brendel, U. S. Schubert
Degradable polycaprolactone nanoparticles stabilized via supramolecular host–guest interactions with pH-responsive polymer-pillar[5]arene conjugates
Polym. Chem. 2020, 11, 1985-1997. - F. Wendler, J. C. Tom, M. Sittig, P. Biehl, B. Dietzek, F. H. Schacher
Block copolymers featuring highly photostable photoacids based on vinylnaphthol: Synthesis and self-assembly
Macromol. Rapid Commun. 2020, 41, 1900607.
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Transcriptional suppression of the NLRP3 inflammasome and cytokine release in primary macrophages by low-dose anthracyclines
Cells 2019, 9, 79. - G. Creusen, A. Roshanasan, J. Garcia Lopez, K. Peneva, A. Walther
Bottom-up design of model network elastomers and hydrogels from precise star polymers
Polym. Chem. 2019, 10, 3740-3750. - F. Wendler, J. C. Tom, F. H. Schacher
Synthesis and self-assembly of photoacid-containing block copolymers based on 1-naphthol
Polym. Chem. 2019, 10, 5602-5616. - D. Bandelli, J. Alex, C. Weber, U. S. Schubert
Polyester stereocomplexes beyond PLA: Could synthetic opportunities revolutionize established material blending?
Macromol. Rapid Commun. 2019, 1900560. - T. Chakraborty, M. K. Driscoll, E. Jeffery, M. M. Murphy, P. Roudot, B.-J. Chang, S. Vora, W. M. Wong, C. D. Nielson, H. Zhang, V. Zhemkov, C. Hiremath, E. D. De La Cruz, Y. Yi, I. Bezprozvanny, H. Zhao, R. Tomer, R. Heintzmann, J. P. Meeks, D. K. Marciano, S. J. Morrison, G. Danuser, K. M. Dean, R. FiolkaLight-sheet microscopy of cleared tissues with isotropic, subcellular resolution
Nat. Meth. 2019, 16, 1109-1113. - C. Favard, J. Chojnacki, P. Merida, N. Yandrapalli, J. Mak, C. Eggeling, D. Muriaux
HIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly
Sci. Adv. 2019, 5, eaaw8651. - E. Romp, V. Arakandy, J. Fischer, C. Wolz, A. Siegmund, B. Löffler, L. Tuchscherr, O. Werz, U. Garscha
Exotoxins from Staphylococcus aureus activate 5-lipoxygenase and induce leukotriene biosynthesis
Cell. Mol. Life Sci. 2019, DOI: 10.1007/s00018-00019-03393-x. - M. Rosales-Guzmán, O. Pérez-Camacho, C. Guerrero-Sánchez, S. Harrisson, R. Torres-Lubián, J. Vitz, U. S. Schubert, E. Saldívar-Guerra
Semiautomated parallel RAFT copolymerization of isoprene with glycidyl methacrylate
ACS Comb. Sci. 2019, 21, 771-781. - F. Wendler, M. Sittig, J. C. Tom, B. Dietzek, F. H. Schacher
Polymeric photoacids based on naphthols - Design criteria, photostability, and light-mediated release
Chem. Eur. J. 2019, DOI: 10.1002/chem.201903819. - R. Meyer, S. Trautmann, K. Rezaei, A. George, A. Turchanin, V. Deckert
Synergy of photoinduced force microscopy and tip-enhanced Raman spectroscopy—A correlative study on MoS2
ACS Photonics 2019, 6, 1191-1198. - J. B. Max, D. V. Pergushov, L. V. Sigolaeva, F. H. Schacher
Polyampholytic graft copolymers based on polydehydroalanine (PDha) – synthesis, solution behavior and application as dispersants for carbon nanotubes
Polym. Chem. 2019, 10, 3006-3019. - J. Langer, D. Jimenez de Aberasturi, J. Aizpurua, R. A. Alvarez-Puebla, B. Auguié, J. J. Baumberg, G. C. Bazan, S. E. J. Bell, A. Boisen, A. G. Brolo, J. Choo, D. Cialla-May, V. Deckert, L. Fabris, K. Faulds, F. J. García de Abajo, R. Goodacre, D. Graham, A. J. Haes, C. L. Haynes, C. Huck, T. Itoh, M. Käll, J. Kneipp, N. A. Kotov, H. Kuang, E. C. Le Ru, H. K. Lee, J.-F. Li, X. Y. Ling, S. Maier, T. Mayerhoefer, M. Moskovits, K. Murakoshi, J.-M. Nam, S. Nie, Y. Ozaki, I. Pastoriza-Santos, J. Perez-Juste, J. Popp, A. Pucci, S. Reich, B. Ren, G. C. Schatz, T. Shegai, S. Schlücker, T. Li-Lin, K. G. Thomas, Z.-Q. Tian, R. P. Van Duyne, T. Vo-Dinh, Y. Wang, K. A. Willets, C. Xu, H. Xu, Y. Xu, Y. S. Yamamoto, B. Zhao, L. M. Liz-MarzánPresent and future of surface enhanced Raman scattering
ACS Nano 2019, DOI: 10.1021/acsnano.1029b04224. - J. Ernst, M. Klinger-Strobel, J. Thamm, O. Makarewicz, M. Pletz, D. Fischer
Breaking the biofilm barrier: The role of stabilizers in biofilm penetration and pulmonary antibiotic delivery by polymer nanoparticles
Pharmazeutische Industrie 2019, 81, 248-255. - J. K. Elter, P. Biehl, M. Gottschaldt, F. H. Schacher
Core-crosslinked worm-like micelles from polyether-based diblock terpolymers
Polym. Chem. 2019, DOI: 10.1039/C1039PY01054H. - V. H. Bac, B. S. Paulsen, L. V. Truong, A. Koschella, T. C. Trinh, C. W. Wold, S. Yogarajah, T. Heinze
Neutral polysaccharide from the leaves of pseuderanthemum carruthersii: Presence of 3-O-methyl galactose and anti-inflammatory activity in LPS-stimulated RAW 264.7 cells
Polymers 2019, 11, 1219. - L. Applová, J. Karlíčková, P. Warncke, K. Macáková, M. Hrubša, M. Macháček, V. Tvrdý, D. Fischer, P. Mladěnka
4-Methylcatechol, a flavonoid metabolite with potent antiplatelet effects
Mol. Nutr. Food Res. 2019, 63, 1900261. - I. Perevyazko, A. Lezov, A. S. Gubarev, E. Lebedeva, G. Festag, C. Guerrero-Sanchez, N. Tsvetkov, U. S. Schubert
Structure-property relationships via complementary hydrodynamic approaches: Poly(2-(dimethylamino)ethyl methacrylate)s
Polymer 2019, 182, 121828. - L. V. Sigolaeva, T. V. Bulko, M. S. Kozin, W. Zhang, M. Köhler, I. Romanenko, J. Yuan, F. H. Schacher, D. V. Pergushov, V. V. Shumyantseva
Long-term stable poly(ionic liquid)/MWCNTs inks enable enhanced surface modification for electrooxidative detection and quantification of dsDNA
Polymer 2019, 168, 95-103. - C. St Thomas, C. N. Muñoz López, E. J. Jiménez Regalado, M. A. de Jesús Tellez, G. Festag, U. S. Schubert, C. Guerrero-Sánchez
Preparation of hydrophobically modified associating multiblock copolymers via a one-pot aqueous RAFT polymerization
Polym. Chem. 2019, DOI: 10.1039/C1039PY01311C. - M. Wang, J. Zhang, C. Guerrero-Sanchez, U. S. Schubert, A. Feng, S. H. Thang
Enzyme degassing for oxygen-sensitive reactions in open vessels of an automated parallel synthesizer: RAFT polymerizations
ACS Comb. Sci. 2019, 21, 643-649. - M. Wallert, M. Ziegler, X. Wang, A. Maluenda, X. Xu, M. L. Yap, R. Witt, C. Giles, S. Kluge, M. Hortmann, J. Zhang, P. Meikle, S. Lorkowski, K. Peterα-Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injury
Redox Biology 2019, 26, 101292. - H. L. Cao, X. Y. Liu, K. D. Jandt
The action-network of nanomaterials in "On the issue of transparency and reproducibility in nanomedicine"
Nat. Nanotechn. 2019, 14, 629-635. - D. Bandelli, C. Weber, U. S. Schubert
Strontium isopropoxide: A highly active catalyst for the ring-opening polymerization of lactide and various lactones
Macromol. Rapid Commun. 2019, 1900306. - Z. Rao, S. Pace, P. M. Jordan, R. Bilancia, F. Troisi, F. Börner, N. Andreas, T. Kamradt, D. Menche, A. Rossi, C. N. Serhan, J. Gerstmeier, O. WerzVacuolar (H+)-ATPase critically regulates specialized proresolving mediator pathways in human M2-like monocyte-derived macrophages and has a crucial role in resolution of inflammation
J. Immunol. 2019, 203, 1031-1043. - H. Würfel, M. Kayser, T. HeinzeNon-aqueous solvent for efficient dissolution of polygalacturonic acid
Carbohydr. Polym. 2019, 207, 791-795. - H. Würfel, M. Kayser, T. HeinzeTrimethylsilylation of Polygalacturonic Acid
Macromol. Chem. Phys. 2019, 220, 1900002. - M. Kostag, M. Gericke, T. Heinze, O. A. El Seoud
Twenty-five years of cellulose chemistry: innovations in the dissolution of the biopolymer and its transformation into esters and ethers
Cellulose 2019, 26, 139-184. - C. Pinon-Balderrama, C. Leyva-Porras, R. Olayo-Valles, J. Revilla-Vazquez, U. S. Schubert, C. Guerrero-Sanchez, J. Bonilla-CruzSelf-assembly investigations of sulfonated poly(methyl methacrylate-block-styrene) diblock copolymer thin films
Adv. Polym. Technol. 2019, 2019, 11. - A. Sierra-Fernandez, S. C. De la Rosa-García, R. Yañez-Macías, C. Guerrero-Sanchez, L. S. Gomez-Villalba, S. Gómez-Cornelio, M. E. Rabanal, U. S. Schubert, R. Fort, P. QuintanaSol–gel synthesis of Mg(OH)2 and Ca(OH)2 nanoparticles: a comparative study of their antifungal activity in partially quaternized p(DMAEMA) nanocomposite films
J. Sol-Gel Sci. Technol. 2019, 89, 310-321. - M. Zink, K. Hotzel, U. S. Schubert, T. Heinze, D. FischerAmino Acid–Substituted Dextran-Based Non-Viral Vectors for Gene Delivery
Macromol. Biosci. 2019, 19, 1900085. - J. Gerstmeier, C. Kretzer, S. Di Micco, L. Miek, H. Butschek, V. Cantone, R. Bilancia, R. Rizza, F. Troisi, N. Cardullo, C. Tringali, A. Ialenti, A. Rossi, G. Bifulco, O. Werz, S. PaceNovel benzoxanthene lignans that favorably modulate lipid mediator biosynthesis: A promising pharmacological strategy for anti-inflammatory therapy
Biochem. Pharmacol. 2019, 165, 263-274. - J. Gerstmeier, J. Seegers, F. Witt, B. Waltenberger, V. Temml, J. M. Rollinger, H. Stuppner, A. Koeberle, D. Schuster, O. Werz
Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis
Frontiers in Pharmacology 2019, 10. - S. Shekfeh, B. Çalışkan, K. Fischer, T. Yalçın, U. Garscha, O. Werz, E. BanogluA Multi‐step Virtual Screening Protocol for the Identification of Novel Non‐acidic Microsomal Prostaglandin E2 Synthase‐1 (mPGES‐1) Inhibitors
ChemMedChem 2019, 14, 273-281. - M. Wallert, J. Bauer, S. Kluge, L. Schmölz, Y.-C. Chen, M. Ziegler, A. K. Searle, A. Maxones, M. Schubert, M. Thürmer, H. Pein, A. Koeberle, O. Werz, M. Birringer, K. Peter, S. LorkowskiThe vitamin E derivative garcinoic acid from Garcinia kola nut seeds attenuates the inflammatory response
Redox Biology 2019, 24, 101166. - M. Reifarth, W. Müller, B. Shkodra-Pula, H. Görls, U. S. Schubert, R. Heintzmann, S. HoeppenerElectron density of polymeric nanoparticles determined by image processing of transmission electron micrographs: Insights into heavy metal staining processes
Particle & Particle Systems Characterization 2019, 1800324. - M. Sahn, C. Weber, U. S. Schubert
Poly(2-oxazoline)-containing triblock copolymers: Synthesis and applications
Polym. Rev. 2019, doi: 10.1080/15583724.2018.1496930. - P. Wei, G. Gangapurwala, D. Pretzel, M. N. Leiske, L. Wang, S. Hoeppener, S. Schubert, J. C. Brendel, U. S. Schubert
Smart pH-sensitive nanogels for controlled release in an acidic environment
Biomacromolecules 2019, 20, 130-140. - M. Werner, P. M. Jordan, E. Romp, A. Czapka, Z. Rao, C. Kretzer, A. Koeberle, U. Garscha, S. Pace, H.-E. Claesson, C. N. Serhan, O. Werz, J. Gerstmeier
Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome
The FASEB Journal 2019, doi: 10.1096/fj.201802509R. - L. Wondraczek, G. Pohnert, F. H. Schacher, A. Köhler, M. Gottschaldt, U. S. Schubert, K. Küsel, A. A. Brakhage
Artificial microbial arenas: Materials for observing and manipulating microbial consortia
Adv. Mater. 2019, 31, 1900284. - B. Shkodra-Pula, C. Grune, A. Traeger, A. Vollrath, S. Schubert, D. Fischer, U. S. Schubert
Effect of surfactant on the size and stability of PLGA nanoparticles encapsulating a protein kinase C inhibitor
Int. J. Pharm. 2019, 566, 756-764. - C. Reichardt, S. Monro, F. H. Sobotta, K. L. Colón, T. Sainuddin, M. Stephenson, E. Sampson, J. Roque, H. Yin, J. C. Brendel, C. G. Cameron, S. McFarland, B. Dietzek
Predictive strength of photophysical measurements for in vitro photobiological activity in a series of Ru(II) polypyridyl complexes derived from π-extended ligands
Inorg. Chem. 2019, 58, 3156-3166. - H. Qiu, Z. Yang, M. Köhler, J. Ling, F. H. Schacher
Synthesis and solution self-assembly of poly(1,3-dioxolane)
Macromolecules 2019, 52, 3359-3366. - N. Engel, M. Dirauf, S. Seupel, M. N. Leiske, S. Schubert, U. S. Schubert
Utilization of 4-(trifluoromethyl)benzenesulfonates as counter ions tunes the initiator efficiency of sophisticated initiators for the preparation of well-defined poly(2-oxazoline)s
Macromol. Rapid Commun. 2019, 40, 1900094. - N. Al Nakeeb, I. Nischang, B. V. K. J. Schmidt
Tannic acid-mediated aggregate stabilization of poly(N-vinylpyrrolidone)-b-poly(oligo (ethylene glycol) methyl ether methacrylate) double hydrophilic block copolymers
Nanomaterials 2019, 9, 662. - M. Maurer, M. S. Gresnigt, A. Last, T. Wollny, F. Berlinghof, R. Pospich, Z. Cseresnyes, A. Medyukhina, K. Graf, M. Gröger, M. Raasch, F. Siwczak, S. Nietzsche, I. D. Jacobsen, M. T. Figge, B. Hube, O. Huber, A. S. Mosig
A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies
Biomaterials 2019, 220, 119396. - M. I. A. Hassan, Z. Cseresnyes, N. Al-Zaben, H.-M. Dahse, R. J. Vilela de Oliveira, G. Walther, K. Voigt, M. T. Figge
The geographical region of origin determines the phagocytic vulnerability of Lichtheimia strains
Environ. Microbiol., DOI: 10.1111/1462-2920.14752. - D. Bandelli, J. Alex, C. Helbing, N. Ueberschaar, H. Görls, P. Bellstedt, C. Weber, K. D. Jandt, U. S. Schubert
Poly(ethylglycolide): A well-defined polyester matching the hydrophilic hydrophobic balance of PLA
Polym. Chem. 2019, DOI: 10.1039/c1039py00875f. - I. Tabujew, C. Cokca, L. Zartner, U. S. Schubert, I. Nischang, D. Fischer, K. Peneva
The influence of gradient and statistical arrangements of guanidinium or primary amine groups in poly(methacrylate) copolymers on their DNA binding affinity
Journal of Materials Chemistry B 2019, DOI: 10.1039/c9tb01269a. - A. Barbotin, S. Galiani, I. Urbančič, C. Eggeling, M. J. Booth
Adaptive optics allows STED-FCS measurements in the cytoplasm of living cells
Optics Express 2019, 27, 23378-23395. - T. Klein, F. V. Gruschwitz, S. Rogers, S. Hoeppener, I. Nischang, J. C. Brendel
The influence of directed hydrogen bonds on the self-assembly of amphiphilic polymers in water
J. Colloid Interface Sci. 2019, 557, 488-497. - M. E. Mikhailova, A. S. Senchukova, A. A. Lezov, A. S. Gubarev, A.-K. Trützschler, U. S. Schubert, N. V. Tsvetkov
Stabilization of Silver Nanoparticles by Cationic Aminoethyl Methacrylate Copolymers in Aqueous Media—Effects of Component Ratios and Molar Masses of Copolymers
Polymers 2019, 11, 1647. - M. Raasch, E. Fritsche, A. Kurtz, M. Bauer, A. S. Mosig
Microphysiological systems meet hiPSC technology - New tools for disease modeling of liver infections in basic research and drug development
Adv. Drug Delivery Rev. 2019, 140, 51-67. - E. Rossegger, F. Pirolt, S. Hoeppener, U. S. Schubert, O. Glatter, F. Wiesbrock
Crosslinkable/functionalizable poly(2-oxazoline)based micelles
Eur. Polym. J. 2019, 121, 109305. - I. Tabujew, M. Heidari, C. Freidel, M. Helm, L. Tebbe, U. Wolfrum, K. Nagel-Wolfrum, K. Koynov, P. Biehl, F. H. Schacher, R. Potestio, K. Peneva
Tackling the limitations of copolymeric small interfering RNA delivery agents by a combined experimental–computational approach
Biomacromolecules 2019, 20, 4389-4406. - I. Tabujew, M. Willig, N. Leber, C. Freidel, I. Negwer, K. Koynov, M. Helm, K. Landfester, R. Zentel, K. Peneva, V. Mailänder
Overcoming the barrier of CD8+ T cells: Two types of nano-sized carriers for siRNA transport
Acta Biomaterialia 2019, 100, 338-351. - R. Yañez-Macías, A. Muñoz-Bonilla, M. A. De Jesús-Tellez, H. Maldonado-Textle, C. Guerrero-Sánchez, U. S. Schubert, R. Guerrero-Santos
Combinations of antimicrobial polymers with nanomaterials and bioactives to improve biocidal therapies
Polymers 2019, 11, 1789. - M. Yarbakht, P. Pradhan, N. Köse-Vogel, H. Bae, S. Stengel, T. Meyer, M. Schmitt, A. Stallmach, J. Popp, T. W. Bocklitz, T. Bruns
Nonlinear multimodal imaging characteristics of early septic liver injury in a mouse model of peritonitis
Anal. Chem. 2019, 91, 11116-11121.
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- F. L. Kriegel, R. Köhler, J. Bayat-Sarmadi, S. Bayerl, A. E. Hauser, R. Niesner, A. Luch, Z. Cseresnyes
Morphology-based distinction between healthy and pathological cells utilizing fourier transforms and self-organizing maps
JoVE 2018, e58543. - N. Teich, T. Bruns, A. Stallmach
Letter: predicting azathioprine-associated pancreatitis in IBD—phenotype or genotype?
Aliment. Pharmacol. Ther. 2018, 47, 1042-1043. - C. Englert, J. C. Brendel, T. C. Majdanski, T. Yildirim, S. Schubert, M. Gottschaldt, N. Windhab, U. S. Schubert,
"Pharmapolymers in the 21st Century: Synthetic Polymers in Drug Delivery Applications",
Prog. Polym. Sci. 2018, DOI: 10.1016/j.progpolymsci.2018.1007.1005. - P. Dasari, I. A. Shopova, M. Stroe, D. Wartenberg, H. Martin-Dahse, N. Beyersdorf, P. Hortschansky, S. Dietrich, Z. Cseresnyés, M. T. Figge, M. Westermann, C. Skerka, A. A. Brakhage, P. F. Zipfel,
"Aspf2 from Aspergillus fumigatus recruits human immune regulators for immune evasion and cell damage",
Front. Immunol. 2018, 9, 1635. - L. Vieider, E. Romp, V. Temml, J. Fischer, C. Kretzer, M. Schoenthaler, A. Taha, V. Hernández-Olmos, S. Sturm, D. Schuster, O. Werz, U. Garscha, B. Matuszczak,
"Synthesis, biological evaluation and structureactivity relationships of diflapolin analogues as dual sEH/FLAP inhibitors",
ACS Med. Chem. Lett. 2018, DOI: 10.1021/acsmedchemlett.8b00415. - M. Brunzel, T. Majdanski, J. Vitz, I. Nischang, U. Schubert,
"Fast screening of diol impurities in methoxy poly(ethylene glycol)s (mPEG)s by liquid chromatography on monolithic silica rods",
Polymers 2018, 10, 1395. - T. C. Majdanski, J. Vitz, A. Meier, M. Brunzel, S. Schubert, I. Nischang, U. S. Schubert,
"Green ethers as solvent alternatives for anionic ring-opening polymerizations of ethylene oxide (EO): In-situ kinetic and advanced characterization studies",
Polymer 2018, 159, 86-94. - M. Dirauf, D. Bandelli, C. Weber, H. Görls, M. Gottschaldt, U. S. Schubert,
"TBD-catalyzed ring-opening polymerization of alkyl-substituted morpholine-2,5-dione derivatives",
Macromol. Rapid Commun. 2018, 39, 1800433. - H. Pein, A. Ville, S. Pace, V. Temml, U. Garscha, M. Raasch, K. Alsabil, G. Viault, C.-P. Dinh, D. Guilet, F. Troisi, K. Neukirch, S. König, R. Bilancia, B. Waltenberger, H. Stuppner, M. Wallert, S. Lorkowski, C. Weinigel, S. Rummler, M. Birringer, F. Roviezzo, L. Sautebin, J.-J. Helesbeux, D. Séraphin, A. Mosig, D. Schuster, A. Rossi, P. Richomme, O. Werz, A. Koeberle,
"Endogenous metabolites of vitamin E limit inflammation by targeting 5 lipoxygenase",
Nat. Commun. 2018, 9, 3834. - H. Würfel, M. Kayser, T. Heinze,
"Efficient and catalyst-free synthesis of cellulose acetoacetates",
Cellulose 2018, 25, 4919-4928. - K. Ganske, T. Heinze,
"Evaluation of the synthesis of soluble aromatic cellulose carbonates of low degree of substitution",
Macromol. Chem. Phys. 2018, 219, 1800152. - T. Bus, A. Traeger, U. S. Schubert,
"The great escape: how cationic polyplexes overcome the endosomal barrier",
J. Mater. Chem. B 2018, 6, 6904-6918. - M. Bauer, L. Tauhardt, H. M. L. Lambermont-Thijs, K. Kempe, R. Hoogenboom, U. S. Schubert, D. Fischer,
"Rethinking the impact of the protonable amine density on cationic polymers for gene delivery: A comparative study of partially hydrolyzed poly(2-ethyl-2-oxazoline)s and linear poly(ethylene imine)s",
Eur. J. Pharm. Biopharm. 2018, 133, 112-121. - J. F. Herrmann, C. Höppener,
"Dumbbell gold nanoparticle dimer antennas with advanced optical properties",
Beilst. J. Nanotechnol. 2018, 9, 2188-2197. - R. Meyer, X. Yao, V. Deckert,
"Latest instrumental developments and bioanalytical applications in tip-enhanced Raman spectroscopy",
Trends Anal. Chem. 2018, 102, 250-258. - D. Bandelli, C. Helbing, C. Weber, M. Seifert, I. Muljajew, K. D. Jandt, U. S. Schubert,
"Maintaining the hydrophilichydrophobic balance of polyesters with adjustable crystallinity for tailor-made nanoparticles",
Macromolecules 2018, 51, 5567-5576. - S.-Y. Cheung, M. Werner, L. Esposito, F. Troisi, V. Cantone, S. Liening, S. König, J. Gerstmeier, A. Koeberle, R. Bilancia, R. Rizza, A. Rossi, F. Roviezzo, V. Temml, D. Schuster, H. Stuppner, M. Schubert-Zsilavecz, O. Werz, T. Hanke, S. Pace,
"Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation",
Eur. J. Med. Chem. 2018, 156, 815-830. - A. Koeberle, A. Henkel, M. Verhoff, L. Tausch, S. König, D. Fischer, N. Kather, S. Seitz, M. Paul, J. Jauch, O. Werz,
"Triterpene acids from Frankincense and semi-synthetic derivatives that inhibit 5-lipoxygenase and cathepsin G",
Molecules 2018, 23, 506. - A.-K. Trützschler, T. Bus, M. Sahn, A. Traeger, C. Weber, U. S. Schubert,
"The power of shielding: Low toxicity and high transfection performance of cationic graft copolymers containing poly(2-oxazoline) side chains",
Biomacromolecules 2018, 19, 2759-2771. - M. Grube, M. N. Leiske, U. S. Schubert, I. Nischang,
"POx as an alternative to PEG? A hydrodynamic and light scattering study",
Macromolecules 2018, 51, 1905-1916. - Z. T. Gür, B. Çalışkan, U. Garscha, A. Olgaç, U. S. Schubert, J. Gerstmeier, O. Werz, E. Banoglu,
"Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7",
Eur. J. Med. Chem. 2018, 150, 876-899. - D. Hertz, M. N. Leiske, T. Wloka, A. Traeger, M. Hartlieb, M. M. Kessels, S. Schubert, B. Qualmann, U. S. Schubert,
"Comparison of random and gradient amino functionalized poly(2-oxazoline)s: Can the transfection efficiency be tuned by the macromolecular structure?",
J. Polym. Sci., Part A: Polym. Chem. 2018, DOI: 10.1002/pola.29000. - M. N. Leiske, F. H. Sobotta, F. Richter, S. Hoeppener, J. C. Brendel, A. Traeger, U. S. Schubert,
"How to tune the gene delivery and biocompatibility of poly(2-(4-aminobutyl)-2-oxazoline) by self- and coassembly",
Biomacromolecules 2018, 19, 748-760. - I. Muljajew, C. Weber, I. Nischang, U. Schubert,
"PMMA-g-OEtOx graft copolymers: Influence of grafting degree and side chain length on the conformation in aqueous solution",
Materials 2018, 11, 528. - M. Reifarth, S. Hoeppener, U. S. Schubert,
"Uptake and intracellular fate of engineered nanoparticles in mammalian cells: Capabilities and limitations of transmission electron microscopypolymerbased nanoparticles",
Adv. Mater. 2018, 30, 1703704. - W. S. Zhang, X. Q. Yu, Y. Li, Z. Q. Su, K. D. Jandt, G. Wei,
"Protein-mimetic peptide nanofibers: Motif design, self-assembly synthesis, and sequence-specific biomedical applications",
Prog. Polym. Sci. 2018, 80, 94-124. - M. Reifarth, U. S. Schubert, S. Hoeppener,
"Considerations for the uptake characteristic of inorgainc nanoparticles into mammalian cells - Insights gained by TEM investigations",
Adv. Biosys. 2018, DOI: 10.1002/adbi.201700254. - M. Sahn, L. M. Stafast, M. Dirauf, D. Bandelli, C. Weber, U. S. Schubert,
"LCST behavior of poly(2-ethyl-2-oxazoline) containing diblock and triblock copolymers",
Eur. Polym. J. 2018, 100, 57-66. - F. H. Sobotta, F. Hausig, D. O. Harz, S. Hoeppener, U. S. Schubert, J. C. Brendel,
"Oxidation-responsive micelles by a one-pot polymerization-induced self-assembly approach",
Polym. Chem. 2018, 9, 1593-1602. - P. Wei, S. Götz, S. Schubert, J. C. Brendel, U. S. Schubert,
"Accelerating the acidic degradation of a novel thermoresponsive polymer by host-guest interaction",
Polym. Chem. 2018, 9, 2634-2642. - A.-K. Trützschler, T. Bus, M. Reifarth, J. C. Brendel, S. Hoeppener, A. Traeger, U. S. Schubert,
"Beyond gene transfection with methacrylate-based polyplexesthe influence of the amino substitution pattern",
Bioconjugate Chem. 2018, 29, 2181-2194. - A. Koeberle, O. Werz,
"Natural products as inhibitors of prostaglandin E2 and pro-inflammatory 5-lipoxygenase-derived lipid mediator biosynthesis",
Biotechnol. Adv. 2018, 36, 1709-1723. - L. Volkmann, M. Köhler, F. H. Sobotta, M. T. Enke, J. C. Brendel, F. H. Schacher,
"Poly(2-acrylamidoglycolic acid) (PAGA): Controlled polymerization using RAFT and chelation of metal cations",
Macromolecules 2018, DOI: 10.1021/acs.macromol.1028b01260. - J. Zhang, B. Farias-Mancilla, M. Destarac, U. S. Schubert, D. J. Keddie, C. Guerrero-Sanchez, S. Harrisson,"Asymmetric copolymers: Synthesis, properties, and applications of gradient and other partially segregated copolymers",
Macromol. Rapid Commun. 2018, 39, 1800357. - S. Miwa, R. Takahashi, C. Rössel, S. Matsumoto, S. Fujii, J. H. Lee, F. H. Schacher, K. Sakurai
Core–shell–corona micelles from a polyether-based triblock terpolymer: Investigation of the pH-dependent micellar structure
Langmuir 2018, 34, 7813-7820. - C. Guerrero‐Sanchez, J. Zhang, J. Vitz, U. S. Schubert
High-throughput synthesis of polymers
in Encyclopedia of Polymer Science and Technology, 2018, doi:10.1002/0471440264.pst0471440668.
- F. L. Kriegel, R. Köhler, J. Bayat-Sarmadi, S. Bayerl, A. E. Hauser, R. Niesner, A. Luch, Z. Cseresnyes
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2017
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- A. T. Press, A. Ramoji, M. vd Lühe, A. C. Rinkenauer, J. Hoff, M. Butans, C. Rössel, C. Pietsch, U. Neugebauer, F. H. Schacher, M. Bauer
Cargocarrier interactions significantly contribute to micellar conformation and biodistribution
NPG Asia Materials 2017, 9, e444. - M. Pröhl, S. Seupel, P. Sungur, S. Höppener, M. Gottschaldt, J. C. Brendel, U. S. Schubert
The influence of the grafting density of glycopolymers on the lectin binding affinity of block copolymer micelles
Polymer 2017, 133, 205-212. - I. Perevyazko, A. S. Gubarev, L. Tauhardt, A. Dobrodumov, G. M. Pavlov, U. S. Schubert
Linear poly(ethylene imine)s: true molar masses, solution properties and conformation
Polym. Chem. 2017, 8, 7169-7179. - R. Heintzmann, T. Huser
Super-resolution structured illumination microscopy
Chem. Rev. 2017, 117, 13890-13908.
- A. T. Press, A. Ramoji, M. vd Lühe, A. C. Rinkenauer, J. Hoff, M. Butans, C. Rössel, C. Pietsch, U. Neugebauer, F. H. Schacher, M. Bauer