Projekt B03

B03

Bioinspired guanidinium-containing nanoparticles for gene delivery
Projekt B03
Graphic: K. Peneva/D. Fischer

Project B03 will focus on the synthesis of high performing carriers like guanidinium containing terpolymers where systematic control of the hydrophilic-hydrophobic balance will be utilized to create safe and efficient carriers for nucleic acids. The terpolymers will be formulated with nucleic acids where the resulting polyplexes will be applied as anti-inflammatory treatment based on NF-kB knockdown which will be tested in cell culture systems like endothelial cells or epithelial intestinal models and M1/M2 macrophages.

Grafik Projekt B03 Grafik Projekt B03 Graphic: K. Peneva/D. Fischer

Principle investigators

Prof. Dr. Kalina Peneva Prof. Dr. Kalina Peneva Image: Prof. Dr. Kalina Peneva

Prof. Dr. Kalina Peneva

Laboratory of Organic and Macromolecular Chemistry (IOMC)
Friedrich Schiller University Jena
Lessingstraße 8
07743 Jena
Phone: +49 3641 9-48790
kalina.peneva@uni-jena.de

 

Prof. Dr. Dagmar Fischer Prof. Dr. Dagmar Fischer Image: Prof. Dr. Dagmar Fischer

Prof. Dr. Dagmar Fischer

Department of Chemistry and Pharmacy
Division of Pharmaceutical Technology
Friedrich-Alexander-Universität Erlangen-Nürnberg
Cauerstr. 6 (Haus 4)
91058 Erlangen
Phone: +49 9131 85-29552
dagmar.fischer@fau.de

Staff

Jan Egger Jan Egger Image: Jan Egger

Jan Egger

Department of Chemistry and Pharmacy
Division of Pharmaceutical Technology
Friedrich-Alexander-Universität Erlangen-Nürnberg
Cauerstr. 6 (Haus 4)
91058 Erlangen
jan.egger@fau.de 

Markus Kötzsche

Laboratory of Organic and Macromolecular Chemistry (IOMC)
Friedrich Schiller University Jena
Humboldtstraße 10
07743 Jena
markus.koetzsche@uni-jena.de

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