Controlling the degradation behavior of polymeric nanoparticles by structurally tailored thermal properties
A chemist works in the synthesis lab.
The project aims to understand the influence of the crystal structure, morphology, thermal and mechanical properties on the release mechanisms of encapsulated guest molecules. For this purpose, polyesters that vary in their degree of crystallinity and / or thermal transition temperatures will be designed while keeping the hydrophilicity constant. Detailed investigations on the thermal and mechanical properties of bare and loaded nanoparticles made from these polyesters will be directly performed in suspension to allow a direct comparison with the release kinetics of encapsulated drugs.
Image: C. Weber
Prof. Dr. Klaus D. Jandt
Otto Schott Institute of Materials Research (OSIM) Friedrich Schiller University of Jena Löbdergraben 32 07743 Jena Phone: +49 3641 9-47730 firstname.lastname@example.org
Prof. Dr. Ulrich S. Schubert
Laboratory of Organic and Macromolecular Chemistry (IOMC) Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Phone: +49 3641 9-48200 email@example.com
Karl Scheuer Otto Schott Institute of Materials Research (OSIM) Löbdergraben 32, 07743 Jena Phone: +49 3641 9-47742 firstname.lastname@example.org