/1619x911+@+0_169.jpeg?height=428&width=760)
Polysaccharide-based nanoparticles are suitable drug carriers, which can be widely modified in terms of structures and properties. These features will be exploited to prepare a matrix for deacetylase inhibitors (HDACi). Since protein acetylation significantly affects regulation of the immune system, HDACi could potentially be useful for the treatment of inflammation and septic shock. Consequently, our goal is to tailor a polysaccharide-based matrix as a controlled release system for HDACi by studying structure-property-relations of polysaccharide esters.
