A chemist works with liquid nitrogen.

A01

Tailor-made multifunctional polymers and nanoparticles with optimized compatibility between biodegradable core and encapsulated drug
A chemist works with liquid nitrogen.

By developing new degradable hydrophobic materials such as polyesterketals and polyesteramides, the project aims at designing these polymers to maximize the encapsulation efficiency for a given drug in a combined experimental and computational approach. Atomistic simulations, combined with machine learning approaches, will be used along with mesoscale simulations of real nanocarrier models for computationally efficient predictions of drug loading capacity, nanoparticle formation, encapsulation, and drug release.

Grafik Projekt A01 Grafik Projekt A01 Graphic: C. Weber/FSU Jena

Principle investigators

Prof. Dr. Ulrich S. Schubert Prof. Dr. Ulrich S. Schubert Image: Anne Günther (University of Jena)

Prof. Dr. Ulrich S. Schubert

Laboratory of Organic and Macromolecular Chemistry (IOMC)
Friedrich Schiller University Jena
Humboldtstraße 10
07743 Jena
Phone: +49 3641 9-48200
ulrich.schubert@uni-jena.de

Prof. Dr. Marek Sierka Prof. Dr. Marek Sierka Image: Prof. Dr. Marek Sierka

Prof. Dr. Marek Sierka

Otto Schott Institute of Materials Research (OSIM)
Friedrich Schiller University Jena
Löbdergraben 32
07743 Jena
Phone: +49 3641 9-47930
marek.sierka@uni-jena.de

Staff

Irina Muljajew Irina Muljajew Image: Irina Muljajew

Irina Muljajew

Laboratory of Organic and Macromolecular Chemistry (IOMC)
Friedrich Schiller University Jena
Humboldtstraße 10
07743 Jena
Phone: +49 3641 9-48581
irina.muljajew@uni-jena.de

Mingzhe Chi Mingzhe Chi Image: Mingzhe Chi

Mingzhe Chi

Otto Schott Institute of Materials Research (OSIM)
Friedrich Schiller University Jena
Löbdergraben 32
07743 Jena
Phone: +49 3641 9-47785
mingzhe.chi@uni-jena.de

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