C01

Dextran derivatives and polyesters are synthesized and used as carrier materials for inhibitors that target inflammatory pathways in hepatic stellate cells to slow down the development of liver fibrosis. Advanced biophotonic imaging is utilized to characterize the inhibitor-loaded nanoparticles in cells or directly in the liver. The nanoparticle induced modulation and activation of stellate cells are also analyzed through omics-methods. These joint efforts allow for novel approaches to therapeutically target hepatic stellate cells.

Grafik Projekt C01

Graphic: S. Schubert