Fluorescent solutions in the synthesis laboratory

A03

Photo-triggered swelling and release from core-shell-corona micelles
Fluorescent solutions in the synthesis laboratory

The goal of this project is to design and characterize (spectroscopically and mechanistically) core-shell-corona nanostructures for visible light-induced spatially and temporally selective delivery of medically active components. We utilize amphiphilic ABC triblock terpolymers for the formation of micelles where the core is capable of chemical up-conversion by triplet-triplet annihilation of low-intensity long-wavelength light to higher-energy photons, which then are capable of activating photoacids in the shell. This then induces swelling and, on a longer perspective, triggered release.

graphical abstract A03 Image: F. Schacher, B. Dietzek

Principle investigators:

Prof. Dr. Benjamin Dietzek

Leibniz Institute of Photonic Technology (IPHT)
Albert-Einstein-Straße 9
07745 Jena
Phone: +49 3641 206332
benjamin.dietzek@leibniz-ipht.de

Prof. Dr. Felix H. Schacher

Institute of Organic Chemistry and Macromolecular Chemistry (IOMC)
Friedrich Schiller University of Jena
Humboldtstraße 10
07743 Jena
Phone: +49 3641 9-48250
felix.schacher@uni-jena.de

Prof. Dr. Klaus D. Jandt

Otto  Schott Institute of Materials Research (OSIM)
Friedrich Schiller University of Jena
Löbdergraben 32
07743 Jena
Phone: +49 3641 9-47730
k.jandt@uni-jena.de

Staff:

Dr. Jessica Tom
Institute of Organic Chemistry and Macromolecular Chemistry (IOMC)
Humboldtstraße 10, 07743 Jena
Phone: +49 3641 9-48287
jessica.tom@uni-jena.de

Maria Sittig
Leibniz Institute of Photonic Technology (IPHT)
Albert-Einstein-Straße 9
07745 Jena
Telefon: +49 3641 9-48300
maria.sittig@leibniz-ipht.de

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